• Title/Summary/Keyword: 개발제형

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키토산 나노 입자를 이용한 약물전달시스템

  • 권익찬;김광명;김성원;정혜선;정서영
    • Polymer Science and Technology
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    • v.15 no.4
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    • pp.396-401
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    • 2004
  • 약물전달시스템 (DDS, drug delivery system)이란 기존 약물의 부작용을 최소화하고 약물이 가지고 있는 효능 및 효과를 최적화시켜 질병치유에 필요한 최소의 약물을 효과적으로 전달하기 위한 제형으로 정의될 수 있다. DDS 분야는 저비용과 짧은 개발기간으로 기존 약물의 새로운 제형개발을 가능하게 함으로써 차세대 바이오산업의 핵심으로 인식되고 있다.(중략)

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Controlled Release of Oxyfluorfen from the Variously Complexed Formulations IV. Effect of Water Level Depths on the Activity of Selected Formulations (수종(數種)의 결합제형(結合劑型)으로부터 Oxyfluorfen의 방출억제연구(放出抑制硏究) IV. 관개심(灌漑甚)에 따른 선발제형(選拔劑型) Oxyfluorfen의 약해(藥害).약효평가(藥效評價))

  • Guh, J.O.;Chon, S.U.;Kuk, Y.I.;Kwon, O.D.
    • Korean Journal of Weed Science
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    • v.11 no.3
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    • pp.159-166
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    • 1991
  • Seven oxyfluorfen formulations were tested for control of 8 weed species and rice injury under four different water depths with various ages of rice seedlings. Among formulations tested, rice injury was slight by formulations of Elvan, Coal Slag, Chitosan and Bentonite B under 0 cm or shallow water depths, and by those of Elvan and Coal Slag under deep water conditions. Weed control was high by Bentonite A and B, and Chitosan, and was low by Elvan. Coal Slag and Sand coated oxyfluorfen, if the target weeds of oxyfluorfen are annual species, further development of Elvan, coal slag, chitosan and Bentonite A would be controlled to increase control efficacy or to decrease rice injury.

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약물전달시스템 기술의 개발동향

  • 성하수;최연수
    • Fiber Technology and Industry
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    • v.8 no.2
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    • pp.183-191
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    • 2004
  • 의약품의 원재료인 약물은 사용 목적과 환자에 따라 정(tablet)이나 주사액과 같은 형태를 가지고 이를 제형(dosage form)이라 하고, 이런 형태의 물체를 제제(pharmaceutical preparations)라 한다. 신약이 대거 출현한 1950년대는 새로운 제형을 개발하는 물리약제학(physical pharmacy)이 활발히 연구되었다. 신약들은 당시의 기술로는 생체 내에서의 작용 등에 대한 명확한 자료와 근거 없이 약효가 있을 것으로 추정되었다. 그러나 분석기술과 기기의 발달로 약물의 체내 정량기술이 발달하면서 약물동태 학 (pharmacokinetics)이나 생물 약제학(biopharmaceutics)이 발달하여 약물의 체내 동태를 경시적으로 추적하는 일이 가능해졌다. (중략)

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Controlled Release of Oxyfluorfen from the Variously Complexed Formulations V. Effect of Water Leakage on Injury and Efficacy of Selected Formulations (수종(數種)의 결합제형(結合劑型)으로부터 Oxyfluorfen의 방출제어연구(放出制御硏究) V. 감수심(減水深)에 따른 선발제형(選拔劑型) Oxyfluorfen의 약해(藥害).약효평가(藥效評價))

  • Guh, J.O.;Kwon, O.D.;Kuk, Y.I.;Chon, S.U.
    • Korean Journal of Weed Science
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    • v.11 no.3
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    • pp.167-173
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    • 1991
  • Various formulations of oxyfluorfen were tested to evaluate effect of weed control efficacy and rice injury as affected by different degrees of water leakages. Rice injury was increased with increased water leakages. The formulations of Elvan, Coal slag and Chitosan gave slight injury to rice under all conditions included in terms of visual ratings, plant height and fresh weight production. However, weed control of most formulations was decreased and increased with increased water leakages for annual weeds and perennial weeds, respectively, Annual weeds were controlled greater than 90~ by all treatments, but perennial weed control was relatively low. Scirpus juncoides was the most tolerant annual weed to Oxyfluorfen. Elvan formulation showed somewhat decreased control of barnyardgrass with increased water leakages. The promising formulations of Oxyfluorfen were Chitosan, Coal slag, Bentonite B and Elvan (if the first releasing rate increased), which injured rice slightly and controlled annual weeds excellently regardless of degrees of water leakages.

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Development and Characterization of O/W Cosmetic Formulations Containing Nipa palm (Nypa fruticans Wurmb) and Finger root (Boesenbergia pandurate) Extracts (니파팜, 핑거루트 추출물을 함유한 O/W 화장품 제형 개발 및 분석)

  • Jun, Yue Jin;Kim, Jin-Hee;Jin, Byung Suk
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.4
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    • pp.922-930
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    • 2021
  • This study was attempted to investigate the availability of nipa palm (Nypa fruticans Wurmb.) and finger root (Boesenbergia pandurata) extracts as natural cosmetic ingredients. For this, O/W cosmetic formulations with different compositions were prepared. The appearance of the cosmetic formulations was compared, and brightness and color values were measured using a colorimeter. Also, the pH, viscosity, and texture of the cosmetic formulations with different compositions were measured, and the effects of the extracts on the properties of the cosmetic formulations were examined. Finally, the UV transmittance and sun protection factor (SPF) index were observed, and the results confirmed the availability of finger root extract as a natural ingredient for UV protection.

Convergence Formulation studies of Diagnostic Ultrasound Transmission Media:focusing on the manufacturing costs and rheology (초음파전파매개물의 융복합 제형 연구 :제조비용, 윤활성에 대하여)

  • Lee, Hye-Nam;Park, Mi-Soon;Park, Yeon-Hwa
    • Journal of Digital Convergence
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    • v.13 no.8
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    • pp.369-374
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    • 2015
  • In this study, by combining a unique purpose and additional aspects of ultrasonic transmission media, a development potential on a new ultrasonic transmission media was sought. The rheological characteristics and the manufacturing cost for each manufactured formulation were compared and analysed with ready-made. An ultrasonic transmission media is to have different functional characteristics according to the following formulation, it was the best in rheological value, low viscosity emulsion with the oil gel. Polymer hydro gel is can be manufactured at low cost compared to other formulations. Emulsion which shows a sharp viscosity difference according to the components of oil and water had a big difference in manufacturing cost. This study can be utilized as the fundamental data on the ultrasound transmission media equipped with expertise in various areas of ultrasound.

Formulation Studies for Surface Modification and Application to Cosmetics of Jadeite Powder (경옥 가루 표면 개질과 화장품에의 응용을 위한 제형 연구)

  • Kim, Yong Woo;Park, Soo Nam
    • Applied Chemistry for Engineering
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    • v.30 no.2
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    • pp.167-177
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    • 2019
  • The jadeite powder has a disadvantage affecting the stability of the formulation due to the agglomeration of the powder when applied to cosmetic formulations. To overcome this problem, a new composite powder was prepared by modifying the surface of jadeite powder and applied to foundation pact and sun stick. In this study, a triethoxycaprylylsilane among various surface modifiers was selected as an optimum component, and applied to each formulation by making the jadeite powder composite. As a result, the foundation pact maintained the clarity of the product color, and the sun stick gave about 30% higher UV blocking effect in the UVB area compared with that of the blank. In the user sensory evaluation, the formulation containing the jadeite powder composite showed a high score for the overall indicator. The stability evaluation of the formulation was also confirmed that it was stable against discoloration, detachment and hardness. In conclusion, the jadeite powder composite is stable as an inorganic pigment which is applicable to cosmetics as a multifunctional material while maintaining the color clarity of the product and acting as a booster for sunscreen agents.