• Title/Summary/Keyword: 감마-선

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The effects of gamma irradiation on the survival and development of Clonorchis sinensis metacercariae (감마선 조사가 흰쥐에서의 간흡충 생존 및 발육에 미치는 영향)

  • 이순형;박양희
    • Parasites, Hosts and Diseases
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    • v.27 no.3
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    • pp.187-196
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    • 1989
  • The effects of gamma irradiation on the survival and development of C. sinensis metacercariae were studied to evaluate the feasibility of irradiation as a control measure for clonorchiasis. Pseudorasbora parve were collected at an endemic river of clonorchiasis and were used for irradiation of the fluke in three schemes. The first (Scheme 1) was irradiation of the isolated metacercariae from the fish followed by infection to experimental rats. The second (Scheme 2) was irradiation of the fish, and then the metacercariae were isolated and in(ected to rats. The third (Scheme 3) was irradiation on the rat livers after infection with normal metacercariae. Irradiation doses varied from 5 to 100 Gy for Schemes 1 and 2, and 10 to 25 Gy for Scheme 3. The rats were sacrificed 2 to 6 weeks after infection. In Scheme 1, the metacercariae irradiated at 50 Gy failed to survive in the rats after 2 or 6 weeks. However, 1 to 44% of the metacercariae irradiated at 5∼30 Gy survived. The estimated LD50 of Scheme 1 was 16.5 Gy. The flukes irradiated in Scheme 2 survived better than those in Scheme 1. The average worm recovery rate in 50 Gy was 28%(7∼39% individually). Increasing the dose up to 100 Gy brought a remarkably low survival rate of an average 1%(0∼3% individually). The LD50 of Scheme 2 was 47.5 Gy. Worm recovery rates in the 10 Gy group of Scheme 3 were 21∼39%, and those in the 25 Gy group were 2% and 34%. Although the metacercariae were irradiated, all of the recovered worms were morphologically normal. Only the worms irradiated with 10 Gy or 25 Gy after 9 days from infection in Scheme 3 showed underdeveloped testes and seminal receptacle. The present results suggest that irradiation of the fish by 100 Gy could be adopted as a control measure for clonorchiasis.

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Genotoxicological Safety of High-Dose Gamma-Irradiated Cereal Powders (고선량 감마선조사 곡류 분말의 유전독성학적 안전성평가)

  • Han Sag-Myung;Kim Hye-Mi;Jeung Seung-Kyoung;Lee Ju-Woon;Byun Myung-Woo;Kang Il-Jun
    • Food Science and Preservation
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    • v.13 no.4
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    • pp.524-529
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    • 2006
  • Gamma irradiation at 30 kGy was applied to cereal powders to evaluate their possible genotoxicity. The genotoxicity of 30 kGy-irradiated cereal powders was evaluated by Salmonella typhimurium reversion assay, chromosomal aberration test and in vivo micronucleus assay. The result were negative in the bacterial reversion assay with S. typhimurium TA98, IA100, TA1535 and TA1537. No mutagenicity was detected in the assay with and without metabolic activation. In chromosomal aberration tests with CHL cells and in vivo mouse micronucleus assay, no significant difference in the incidences of chromosomal aberration and micronuclei was observed between non-irradiated and 30 kGy-irradiated cereal powders. These result indicate that cereal powders irradiated at 30 kGy did not show any genotoxic effect under these experimental conditions.

Fabrication and Performance of Microcolumnar CsI:Tl onto Silicon Photomultiplier (실리콘광증배관 기반의 미세기둥 구조 CsI:Tl 제작 및 평가)

  • Park, Chan-Jong;Kim, Ki-Dam;Joo, Koan-Sik
    • Journal of IKEEE
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    • v.20 no.4
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    • pp.337-343
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    • 2016
  • This study conducted the gamma ray spectroscopic analysis of the microcolumnar CsI:Tl deposited onto the SiPMs using thermal evaporation deposition. The SEM measured thickness of microcolumnar CsI:Tl and of its individual columns. From the SEM observation, the measured thickness of CsI:Tl were $450{\mu}m$ and $600{\mu}m$. The gamma ray spectroscopic properties of microcolumnar CsI:Tl, $450{\mu}m$ and $600{\mu}m$ thick deposited onto the SiPMs were analyzed using standard gamma ray sources $^{133}Ba$ and $^{137}Cs$. The spectroscopic analysis of microcolumnar CsI:Tl deposited onto the SiPMs included the measurements of response linearity over the $^{137}Cs$ gamma ray intensity; and gamma ray energy spectrum. Furthermore from the gamma ray spectrum measurement of $^{133}Ba$ and $^{137}Cs$, $450{\mu}m$ thick CsI:Tl showed good efficiency when measured with $^{133}Ba$ and $600{\mu}m$ thick CsI:Tl was highly efficient when measured with $^{137}Cs$.

Changes of Microbiological and Physicochemical Characteristics of Doenjang Prepared with Low Salt Content and Gamma Irradiation (감마선 조사와 저염함량으로 제조한 된장의 미생물 및 품질특성 변화)

  • Park, Byoung-Jun;Jang, Kyu-Sub;Kim, Dong-Ho;Yook, Hong-Sun;Byun, Myung-Woo
    • Korean Journal of Food Science and Technology
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    • v.34 no.1
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    • pp.79-84
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    • 2002
  • Changes of microbiological and physicochemical characteristics of gamma irradiated Doenjang with low salt were studied. Samples were prepared by mixing the Doenjang and the Chungkukjang with 6% and 8% of salinity. The mixture was irradiated by gamma-ray with dose of 0, 5, 10, 20 kGy, and each sample was stored at $25^{\circ}C$ for 8 weeks. The results showed that the Bacillus cell was inactivated by $10^4-10^5\;cells/g$ with dose of 10 kGy, and yeast and Lactobacillus group were nearly eliminated by 10 kGy. The general quality of gamma irradiated low salt Doenjang, such as amino nitrogen, protease activity, and pH, were more stable than that of control during storage periods. The sensory evaluations showed that 8% (salt)-5 kGy and 6% (salt)-10 kGy irradiated samples were more acceptable than market purchased Doenjang. Therefore, it was considered that gamma irradiation was effective for maintaining better quality of low salt Doenjang and suitable radiation dose was 5 kGy in 8% salted, and 10 kGy in 6% salted sample.

Microbiological Safety of Minimally Processed White Radish in Modified Atmosphere Packaging Combined with Irradiation Treatment (가스치환포장과 감마선조사 병용 처리한 최소가공 무의 미생물학적 안전성)

  • Kim, Jae-Kyung;Jo, Cheo-Run;Kim, Hyun-Ju;Lee, Ju-Woon;Hwang, Han-Joon;Byun, Myung-Woo
    • Korean Journal of Food Science and Technology
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    • v.37 no.1
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    • pp.11-14
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    • 2005
  • White radish was minimally processed, packed with air, $CO_{2}$ (100%), and $CO_{2}/N_{2}$ (25/75%), and irradiated at 0, 1, and 2 kGy, and its microbiological quality and pH were investigated during storage for 2 weeks at $4^{\circ}C$. Irradiation significantly reduced total aerobic, coli-form, and lactic acid bacteria counts. Modified atmosphere packaging (MAP) enhanced microorganism control during storage. Acidity decreased by MAP but was restored during storage, Irradiation did not affect sample pH. Results show irradiation at 2 kGy combined with MAP can enhance microbiological safety and quality of minimally processed radish.

Evaluation of Heat Production in Deep Boreholes by Gamma-ray Logging (감마선 검층자료를 이용한 국내 대심도 시추공 암반의 열생산율 평가)

  • Jo, Yeonguk;Kim, Myung Sun;Lee, Keun-Soo;Park, In Hwa
    • Geophysics and Geophysical Exploration
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    • v.24 no.1
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    • pp.20-27
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    • 2021
  • Subsurface rock produces heat from the decay of radioactive isotopes in constituent minerals and gamma-ray emissions, of which the magnitude is dominated by the contents of the major radioactive isotopes (e.g., U, Th, and K). The heat production is generally calculated from the rock density and contents of major isotopes, which can be determined by mass spectrometry of drilled core samples or rock fragments. However, such methods are not easily applicable to deep boreholes because core samples recovered from depths of several hundred meters to a few kilometers are rarely available. A geophysical logging technique for boreholes is available where the U, Th, and K contents are measured from the gamma-ray spectrum. However, this technique requires the density to be measured separately, and the measurement depth of the equipment is still limited. As an alternative method, a normal gamma-ray logging tool was adopted to estimate the heat production from the total gamma activity, which is relatively easy to measure. This technical report introduces the development of the proposed method for evaluating the heat production of a granitic rock mass with domestic commercial borehole logging tools, as well as its application to a ~2 km deep borehole for verification.

A Study on Image Acquisition of Gamma Camera using Simulation LUT and MLPE (시뮬레이션 순람표와 최대우도함수를 이용한 감마카메라의 영상 획득 연구)

  • Lee, Seung-Jae
    • Journal of the Korean Society of Radiology
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    • v.15 no.4
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    • pp.409-414
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    • 2021
  • In order to acquire an image from a gamma camera, linearity correction must be performed. To this end, digital coordinates are acquired by using a linearity map to accurately specify the location where the scintillator and gamma rays interact. In this study, a method for acquiring undistorted images and digital coordinates was developed using a lookup table and maximum likelihood position estimation without using a linearity map. The proposed method was verified by configuring a small gamma camera through DETECT2000 simulation. A gamma camera was constructed using a GAGG scintillator and a SiPM optical sensor, and a gamma-ray interaction was generated at the center of the scintillator, and a lookup table was prepared using the ratio of the signals obtained from the SiPM. Through the prepared lookup table and the maximum likelihood position estimation, the position of the signal obtained by the gamma-ray interaction was acquired as digital coordinates to compose an image. As a result, the linearity was maintained compared to the generally acquired image, the accuracy of the location where the gamma-ray interaction was generated was excellent, and the distance between the locations was uniform. Since the lookup table obtained through simulation is created using the ratio of the signal, it can be directly used in the experiment, and the position of the signal can be conveniently obtained with digital coordinates with corrected linearity without creating a linearity map.

Comparative Measurement of Radioactivity with Standard Gamma-ray Ionization Chamber System (표준 감마선 전리함 장치에 의한 방사능 비교 측정)

  • Park, Tae-Soon;Woo, Dong-Ho;Oh, Pil-Jae;Hwang, Sun-Tae
    • Journal of Radiation Protection and Research
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    • v.9 no.1
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    • pp.11-18
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    • 1984
  • A Standard gamma-ray ionization chamber system was developed with a well type ionization chamber and micro current measuring circuit. Micro current was measured by the automatic Townsend balance with stepwise compensation method. For gamma emitting nuclides such as $^{241}Am,\;^{133}Ba,\;^{60}Co,\;^{134}Cs,\;^{137}Cs,\;and\;^{22}Na$ relative calibration factors to $^{226}Ra$ reference source were calculated and detection .efficiency curve was determined as a fudnction of gamma energy.

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Development of Two-dimensional Prompt-gamma Measurement System for Verification of Proton Dose Distribution (이차원 양성자 선량 분포 확인을 위한 즉발감마선 이차원분포 측정 장치 개발)

  • Park, Jong Hoon;Lee, Han Rim;Kim, Chan Hyeong;Kim, Sung Hun;Kim, Seonghoon;Lee, Se Byeong
    • Progress in Medical Physics
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    • v.26 no.1
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    • pp.42-51
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    • 2015
  • In proton therapy, verification of proton dose distribution is important to treat cancer precisely and to enhance patients' safety. To verify proton dose distribution, in a previous study, our team incorporated a vertically-aligned one-dimensional array detection system. We measured 2D prompt-gamma distribution moving the developed detection system in the longitudinal direction and verified similarity between 2D prompt-gamma distribution and 2D proton dose distribution. In the present, we have developed two-dimension prompt-gamma measurement system consisted of a 2D parallel-hole collimator, 2D array-type NaI(Tl) scintillators, and multi-anode PMT (MA-PMT) to measure 2D prompt-gamma distribution in real time. The developed measurement system was tested with $^{22}Na$ (0.511 and 1.275 MeV) and $^{137}Cs$ (0.662 MeV) gamma sources, and the energy resolutions of 0.511, 0.662 and 1.275 MeV were $10.9%{\pm}0.23p%$, $9.8%{\pm}0.18p%$ and $6.4%{\pm}0.24p%$, respectively. Further, the energy resolution of the high gamma energy (3.416 MeV) of double escape peak from Am-Be source was $11.4%{\pm}3.6p%$. To estimate the performance of the developed measurement system, we measured 2D prompt-gamma distribution generated by PMMA phantom irradiated with 45 MeV proton beam of 0.5 nA. As a result of comparing a EBT film result, 2D prompt-gamma distribution measured for $9{\times}10^9$ protons is similar to 2D proton dose distribution. In addition, the 45 MeV estimated beam range by profile distribution of 2D prompt gamma distribution was $17.0{\pm}0.4mm$ and was intimately related with the proton beam range of 17.4 mm.

Microbiological and Organoleptic Qualities of Boiled-Dried Anchovies during Post-Irradiation Period (감마선 조사 건멸치의 미생물학적 및 관능적 품질안정성)

  • 권중호;변명우;김정숙
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.2
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    • pp.283-287
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    • 1996
  • 건멸치의 품질안정성 연구를 위하여 접합필름(nylon $15\mu\textrm{m}/polyethylene$ $100\mu\textrm{m})으로$ 포장된 시료에 감마선을 조사한 다음 상온과 $저온(5~10^{\circ}C)에$ 1년간 저장하면서 미생물학적 및 관능적 품질을 평가하였다. 건멸치에 오염된 미생물의 방사선감수성은 위생지표 미생물>호염성세균>효모 및 곰팡이의 순으로 나타났으며, 5kGy 범위의 감마선 조사는 저온 및 상온에서도 미생물학적 품질을 1년 이상 유지할수 있었다. 관능적품질에 있어서 시료의 겉모양(갈변)과 맛 기호성은 10kGy의 고선량 조사시 대조군보다 유의적으로 저하되었다(p<0.05). 접합필름 포장시료를 5kGy 조사하여 상온과 저온에 1년간 저장하였을 때 관능적 품질은 저장온도별로 유의적인 차이가 나타났으며(p<0.01), 상온에서는 6개월 이상, 저온에서는 1년 이상 상품성 유지가 가능하였다.

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