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Genotoxicological Safety of High-Dose Gamma-Irradiated Cereal Powders  

Han Sag-Myung (Department of Food Science and Nutrition & The Korean Institute of Nutrition, Hallym University)
Kim Hye-Mi (Department of Food Science and Nutrition & The Korean Institute of Nutrition, Hallym University)
Jeung Seung-Kyoung (Department of Food Science and Nutrition & The Korean Institute of Nutrition, Hallym University)
Lee Ju-Woon (Division of Radiation Application Research, Korea Atomic Energy Research Institute)
Byun Myung-Woo (Division of Radiation Application Research, Korea Atomic Energy Research Institute)
Kang Il-Jun (Department of Food Science and Nutrition & The Korean Institute of Nutrition, Hallym University)
Publication Information
Food Science and Preservation / v.13, no.4, 2006 , pp. 524-529 More about this Journal
Abstract
Gamma irradiation at 30 kGy was applied to cereal powders to evaluate their possible genotoxicity. The genotoxicity of 30 kGy-irradiated cereal powders was evaluated by Salmonella typhimurium reversion assay, chromosomal aberration test and in vivo micronucleus assay. The result were negative in the bacterial reversion assay with S. typhimurium TA98, IA100, TA1535 and TA1537. No mutagenicity was detected in the assay with and without metabolic activation. In chromosomal aberration tests with CHL cells and in vivo mouse micronucleus assay, no significant difference in the incidences of chromosomal aberration and micronuclei was observed between non-irradiated and 30 kGy-irradiated cereal powders. These result indicate that cereal powders irradiated at 30 kGy did not show any genotoxic effect under these experimental conditions.
Keywords
cereal powders; gamma irradiation; genotoxicity;
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Times Cited By KSCI : 2  (Citation Analysis)
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