• Title/Summary/Keyword: 간헐주입

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The clinical Analysis of the Intermittent Warm Blood Cardioplegia by Admixing Potassium Only (포타슘만을 이용한 간헐적 온혈액 심정지술의 임상적 고찰)

  • Song, Hyun;Lim, Han-jung;Je, Hung-kon;Yu, Yang-gi;Sorkine, Vitality;Matsuda, Naruto;Choo, Suk-Jung;Lee, Jae-Won;Song, Myung-gun
    • Journal of Chest Surgery
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    • v.34 no.3
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    • pp.224-230
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    • 2001
  • 배경: 지속적인 온혈 심성지액을 이용한 심금 보호술이 소개된 이수, 이를 토대로 많은 임상결과가 발표되고 있다. 그러나 지속적 심정지액 주입에 따른 적정한 수술시야 확보와 역행성 관류법에 따른 우심실 보호에 대한 문제들이 제기 되고 있다. 이에 Antonio 등은 포타슘만을 이용한 간헐적 온혈액 심정지술을 이용하여 만족할 만한 임상결과를 보고 하였다. 본 임상연구는 포타슘만을 이용한 간헐적 온혈액 심정지술을 이용하여, 개심술을 시행 받은 70례의 환잔의 임상결과를 분석하여 그 유용성을 알아보고자 하였다. 대상 및 방법: 1998년 5월부터 1999년 1월까지 포타슘만을 이용한 간헐적 온혈액 심정지술을 이용하여 관상동맥 우회술 및 판막수술을 시행한 70명의 환자와 같은 기간 간헐적 냉혈액 심성지술을 이용하여 동일 술자에 의해 수술을 시행한 70명의 임상결과를 비교 분석하였다. 결과: 총 심폐기 사동 시간(98.7$\pm$6.0분, 114.3$\pm$7.5분, p=0.018),수술중 심정지를 위해 필요한 심정지액의 양(1463.0$\pm$68.0cc, 3584.0$\pm$179.0cc, p<0.001), 의식이 회복될 때까지의 시간(3.5$\pm$0.4시간, 4.9$\pm$0.8시간, p=0.044), 기관 삽관의 제거까지의 시간(10.8$\pm$0.8시간, 13.2$\pm$0.6시간, p=0.017), 부정액으로 리도케인(Lidocaine)의 도움이 필요한 경우(75.2$\pm$6.8mg, 114.5$\pm$7.2mg, p=0.006)등에 있어서는 포타슘만을 이용한 간헐적 온혈액 심정지술이 유의성의 있었고, 술수 심근효소의 상승, 사망률과 이환율에 있어서는 두군간의 유의성은 없었다. 결론: 관상동맥 우회술 및 판막수술에 있어 포타슘만을 이용한 간헐적 온혈액 심정지술은 적어도 간헐적 냉혈액 심정지술과 같은 정도의 심근 보호를 할 수 있었으며, 기존의 warm heart surgery의 장점인 심폐기 가동시간이 짧고, 의식회복이 빠른 점과 함께 용적과부학(volume loading)를 줄일 수 있는 장점이 있어 유용한 심근 보호술의 하나로 사료된다.

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Assessment of Optimum Hydraulic Retention Time (HRT) for Maximum Biogas Production and Total Volatile Solid (TVS) Removal Efficiency of Semi-Continuously Fed and Mixed Reactor (SCFMR) Fed with Dairy Cow Manure (젖소분뇨로부터 최대 바이오가스 생산과 유기물 제거효율을 달성하기 위한 반건식 간헐주입 연속혼합 혐기성반응조의 최적 수리학적 체류시간 도출을 위한 연구)

  • Kang, Ho;Kim, Sun-Woo;Jeong, Ji-Hyun;Ahn, Hee-Kwon;Jung, Kwang-Hwa
    • Journal of Korean Society of Environmental Engineers
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    • v.37 no.12
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    • pp.696-704
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    • 2015
  • This study was carried out to evaluate the optimum operational condition of Semi-continuously Fed and Mixed Reactor (SCFMR) to treat the dairy cow manure and saw dust mixture. Step-wise increase in organic loading rates (OLRs) or decrease in hydraulic retention times (HRTs) were utilized until the biogas volume became significantly decreased at mesophilic temperature ($35^{\circ}C$). The optimum operating condition of the SCFMR fed with TS 13% dairy cow manure and saw dust mixture was found to be an HRTs of 25 days and its corresponding OLRs of $4.45kg\;VS/m^3-day$. At this condition the biogas and methane production rates were 1.44 v/v-d and 1.12 v/v-d (volume of biogas per volume of reactor per day), respectively and the TVS removal efficiency of 37% was achieved. The successful operation with such a high OLR was due to the high reactor alkalinity concentration of 14,500~15,600 mg/L as $CaCO_3$ as a result of the characteristic of the original substrate, dairy cow manure and saw dust mixture whose alkalinity was more than 8,000 mg/L as $CaCO_3$. The parameters for the reactor stability, the ratios of volatile acids and alkalinity concentrations (V/A) and the ratio of propionic acid and acetic acid concentrations (P/A) appeared to be 0.11 and 0.43, respectively, that were greatly stable in operation. Free ammonia toxicity was not experienced due to the long term acclimation by the reactor TS content ranged 7.2~10.4% during the entire operational period.

Intelligent Controller for Optimal Coagulant Dosage Rate in Water Treatment Process (정수장 약품 최적 주입률 결정을 위한 지능형 제어기 개발)

  • Lee, Ho-Hyun;Shin, Gang-Wook;Hong, Sung-Taek;Chun, Myung-Geun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.25 no.4
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    • pp.369-376
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    • 2015
  • Chemicals are injected in order to remove a variety of organic substances contained in the water purification plant influent. It can be determined with measuring sedimentation turbidity 4~7 hours later, whether the chemical dosage rate is proper or not, which make the real-time feedback control impossible. In addition, manual operation in accordance with the Jar-Test carried out in the laboratory and the operator's experience may cause the experimental and human error by the changes of organic characteristics and water quality. Especially at night ad weekend, the rate have been determined only by the operator judgment owing to environment engineer's absence. Therefore, the decision of optimal chemical dosage rate using proposed intelligent control algorithm is expected to result in real-time injection and cost reduction.

A Study on the Improvement of Treatment Efficiency for Nitrogen and Phosphorus in Livestock Treatment System Using Constructed Wetlands (인공습지 축산폐수처리시스템에서 질소 및 인 처리효율 향상 방안)

  • Seo, Dong-Cheol;Park, Jong-Hwan;Kim, Ah-Reum;Kim, Sung-Hun;Lee, Seong-Tea;Jeong, Tae-Uk;Choi, Jeong-Ho;Lee, Sang-Won;Kim, Hyun-Ook;Cho, Ju-Sik;Heo, Jong-Soo
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.3
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    • pp.434-441
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    • 2011
  • To improve T-N and T-P removal efficiencies, removal efficiencies of pollutants in full-scale livestock wastewater treatment plant by natural purification method with water plant filtration and activated sludge beds were investigated under different re-injection rates and injection methods of livestock wastewater. The removal rates of COD, SS, T-N, and T-P in effluent in full-scale livestock wastewater treatment plant were in the order of 30% < 70% ${\leq}$ 100 % at different re-injection rates. The removal rates of pollutants in effluent in full-scale livestock wastewater treatment plant were higher as re-injection rate of livestock wastewater increased. Removal rates of COD, SS, T-N, and T-P by continuous injection were slightly higher than those by intermittent injection method in full-scale livestock wastewater treatment plant. Removal rates of COD, SS, T-N, and T-P by continuous injection method in full-scale livestock wastewater treatment plant with water plant filtration and activated sludge beds were 99.5, 99.8, 99.0 and 99.8%, respectively.

Exopolysaccharide Production in Fed-batch and Continuous Culture by Methylomonas mucosa (Methylomonas mnosa에 의한 Exopolysaccharide의 유가식 및 연속 생산)

  • 장호남;권선훈심상준
    • KSBB Journal
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    • v.8 no.2
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    • pp.164-171
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    • 1993
  • The production of extracellular polysaccharide by Methylomonas mucosa (NRRL B-5696) was investigated. The microorganism uses methanol as the carbon source for their growth and produces exopolysaccharides. The productivity of exopolysaccharides was investigated under various culture modes: batch, fed-batch and continuous culture. In flask culture the growth of cell mass and the production of polysaccharide were inhibited at above 1% (v/v) methanol. At 1%(v/v) methanol maximum specific growth rate was obtained. As C/N ratio (g methanol/g ammonium sulfate) increased, polysaccharide production increased and cells mass decreased. Magnesium ion was also found to be essential for the polysaccharide production. In batch culture the production of polysaccharides was more affected by the specific growth rate than the cell concentration. In fed-batch culture the concentration of polysaccharide was 4 times higher than that of batch culture, but the yield was lower. The productivity of fed-batch with continuous feeding was higher than that of batch or fed-batch with intermittent feeding. This is due to no methanol limitation or inhibition that used to occur in fed-batch culture with intermittent feeding. In continuous culture pure oxygen was supplied to avoid the oxygen limitation. As the dilution rate in- creased up to 0.21 h-1, the yield and productivity increased. The solution viscosity of the produced polysaccharide obtained from above increased exponentially with the concentration of polysaccharide.

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Horizontal Flow Zeolite-Filled Reed Bed with Intermittent Feeding for Sewage Treatment (수평 흐름 제올라이트 갈대 여과상에 의한 생활하수 처리)

  • Seo Jeoung-Yoon;Kim Ean-Ho
    • KSBB Journal
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    • v.21 no.1 s.96
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    • pp.28-33
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    • 2006
  • A sewage was treated using a horizontal flow zeolite-filled reed bed. The sewage from the student dormitory of Changwon National University was fed into the reed bed for 10 minutes every 6 hours at the hydraulic load of $314L/m^2$ day. The filtering height of the reed bed was 100 cm and the zeolite mixture was filled in the reed bed. The mixture consisted of the same volume of two types of zeolite : $0.5{\sim}1mm$ and $1{\sim}3mm$ in diameter. Annual average removal efficiency was SS $88.5%,\;COD_{cr},\;86.1%,\;COD_{Mn}\;81.0%,\;T-N\;48.6%,\;NH_4^+-N\;97.1%$ and T-P 42.8%. T-N of effluent was mostly $NO_3^--N$ and the concentration of $NO_2^--N$ in effluent was lower than 0.1 mg/L. All removal efficiencies did not show a remarkable seasonal change.

Enact of Ischemic Preconditioning on Myocardial Protection A Comparative Study between Normothermic and Moderate Hypothermic Ischemic Hearts Induced by Cardioplegia in Rats - (허혈 전처치가 심근보호에 미치는 영향 -적출 쥐 심장에서 상온에서의 심근허혈과 중등도 제체온하에서 심근정지액 사용 시의 비교 연구-)

  • 조성준;황재준;김학제
    • Journal of Chest Surgery
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    • v.36 no.4
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    • pp.242-254
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    • 2003
  • Most of the studies conducted have investigated the beneficial effects of ischemic preconditioning on normothermic myocardial ischemia. However, the effect of preconditioning could be attenuated through the use of multidose cold cardioplegia as practiced in contemporary clinical heart surgical procedures. The purpose of this study was to investigate whether preconditioning improves postischemic cardiac function in a model of 25℃ moderate hypothermic ischemic heart induced by cold cardioplegia in isolated rat hearts. Material and Method: The isolated Sprague-Dawley rat hearts were randomly assigned to four groups. All hearts were perfused at 37℃ for 20 minutes with Krebs-Henseleit solution before the baseline hemodynamic data were obtained. Group 1 consisted of preconditioned hearts that received 3 minutes of global ischemic preconditioning at 37℃, followed by 5 minutes of reperfusion before 120 minutes of cardioplegic arrest (n=6). Cold (4℃) St. Thomas Hospital cardioplegia solution was infused to induce cardioplegic arrest. Maintaining the heart at 25℃, infusion of the cardioplegia solution was repeated every 20 minutes throughout the 120 minutes of ischemic period. Group 2 consisted of control hearts that underwent no manipulations between the periods of equilibrium and 120 minutes of cardioplegic arrest (n=6). After 2 hours of cardioplegic arrest, Krebs solution was infused and hemodynamic data were obtained for 30 minutes (group 1, 2: cold cardioplegia group). Group 3 received two episodes of ischemic preconditioning before 30 min of 37℃ normothermic ischemia and 30 minutes of reperfusion (n=6). Group 4 served as ischemic controls for group 3 (group 3, 4: warm ischemia group). Result: Preconditioning did not influence parameters such as left ventricular systolic pressure (LVSP), left ventricular end-diastolic pressure (LVEDP), rate-pressure product (RPP) and left ventricular dp/dt (LV dp/dt) in the cold cardioplegia group. (p=NS) However, preconditioning before warm ischemia attenuated the ischemia induced cardiac dysfunction, improving the LVSP, LVEDP, RPP, and LVdp/dt. Less leakage of CPK and LDH were observed in the ischemic preconditioning group compared to the control group (p<0.05). Conclusion: Ischemic preconditioning improved postischemic cardiac function after warm ischemia, but did not protect cold cardioplegic hearts.

An Experimental Study on Surfactant Enhanced LNAPL Removal Behavior in Saturated Zone (계면활성제를 이용한 포화지층내 저비중 비수용성 유기용매의 제거거동에 관한 연구)

  • 이재원;박규홍;박준범;임경희
    • Journal of the Korean Geotechnical Society
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    • v.15 no.5
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    • pp.291-300
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    • 1999
  • Surfactant flushing for enhancing the removal of BTEX from contaminated sand/clay mixtures was investigated. Eight soil columns packed with relatively undisturbed BTEX contaminated soils, were leached with water, methyl alcohol and then flushed with surfactant with or without several additives. Initial concentrations of BTEX mixture range from 278mg/kg to 1975mg/kg. Initial BTEX removal efficiency was 98% when the contaminated soil was flushed with water of 850 pore volumes. Because of tailing effect, water flushing could not remove below 8mg/kg concentrations during the experimental period. Eventually, the most effective surfactant for flushing was turned out to be 4% SOFTANOL(equation omitted)-90 with 3% ethyl alcohol and 3% SXS. In interrupted flow conditions, the removal efficiency was 99.5% with the flushed water of 95 pore volumes. The BTEX mixture removed from the soil columns during the surfactant flushing ranges from 84.5% to 99.5% of the initial amount for both water leaching(850 pore volumes) and surfactant flushing(95-165 pore volumes), respectively. Test results indicated that surfactant flushing could enhance the removal of BTEX mixture from contaminated soils and could reduce the aqueous phase BTEX mixture concentration in leachate.

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Economic implications of optimal operating conditions in a full-scale continuous intermittent cycle extended aeration system (ICEAS) (실규모 연속유입간헐폭기 공정(ICEAS)에서 최적운전조건이 경제성에 미치는 영향)

  • Yong-jae Jeong;Yun-Seong Choi;Seung-Hwan Lee
    • Journal of Korean Society of Water and Wastewater
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    • v.38 no.1
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    • pp.29-38
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    • 2024
  • Wastewater management is increasingly emphasizing economic and environmental sustainability. Traditional methods in sewage treatment plants have significant implications for the environment and the economy due to power and chemical consumption, and sludge generation. To address these challenges, a study was conducted to develop the Intermittent Cycle Extended Aeration System (ICEAS). This approach was implemented as the primary technique in a full-scale wastewater treatment facility, utilizing key operational factors within the standard Sequencing Batch Reactor (SBR) process. The optimal operational approach, identified in this study, was put into practice at the research facility from January 2020 to December 2022. By implementing management strategies within the biological reactor, it was shown that maintaining and reducing chemical quantities, sludge generation, power consumption, and related costs could yield economic benefits. Moreover, adapting operations to influent characteristics and seasonal conditions allowed for efficient blower operation, reducing unnecessary electricity consumption and ensuring proper dissolved oxygen levels. Despite annual increases in influent flow rate and concentration, this study demonstrated the ability to maintain and reduce sludge production, electricity consumption, and chemical usage. Additionally, systematic responses to emergencies and abnormal situations significantly contributed to economic, technical, and environmental benefits.

Evaluation of Extraction Mode for SVE Process by On-Line Monitoring System (온라인 모니터링에 의한 디젤오염토양의 토양증기추출 공정시 추출모드 평가)

  • Park, Joon-Seok;Kim, Seung-Ho;Park, Young-Goo
    • Journal of the Korea Organic Resources Recycling Association
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    • v.11 no.4
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    • pp.90-96
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    • 2003
  • This study was performed to evaluate effect of extraction mode on SVE efficiency for fuel-contaminated soil. A gas station was selected for this study. As a result of pressure test in well head, soil texture of contaminated site under the gas station was very different from site to site. SVE system was operated in intermittent mode (1hr extraction / 3hr rest) or continuous mode. Capacity of air blower was $1m^3/min$. Extration mode test was conducted in two severe contaminated sites. In both two sites, cumulative TPHgas mass of intermittent extraction mode was higher than that of continuous mode. Considering long term operation of SVE in a field, in general, it was thought that intermittent extraction mode was effective in view of vaporized TPHgas mass and electrical cost.

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