• Title/Summary/Keyword: 丁時翰

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Comparison between Manifest Refraction and Cycloplegic Refractin for the First-time Spectacle Wearers (최초 안경착용자의 현성굴절검사(MR)와 조절마비굴절검사(CR)의 비교)

  • Kim, Hye-Ran;Choi, Sun-Mi
    • Journal of Korean Ophthalmic Optics Society
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    • v.13 no.4
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    • pp.145-149
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    • 2008
  • Purpose: To study the difference between refractive errors obtained from manifest refraction (MR) and cycloplegic refraction (CR) in first-time spectacle wearers. To study the difference between manifest refractive errors and cycloplegic refractive errors in first-time spectacle wearers. Methods: From January 2002 to December 2002, manifest and cycloplegic refractions were carried out on the patients who visited an ophthalmology clinic for a spectacle prescription for the first-time. The patients were 509 male and 499 female patients aged between from 3 to 15 years old. Results: The cycloplegic refraction showed a less myopia and a more hyperopia compared with the non-cycloplegic refraction. The differences were more in female patients. The CR showed a less myopic and a more hyperopic refractive errors than the MR. The differences were more in female patients. The average results from a pre- and a post-cycloplegic refraction showed a reduction of -0.22D in male, and -0.20D in female for the myopic group. For the myopic group, the myopic refractive errors by MR were -0.22D in male and -0.20D in female higher than the refractive errors by CR. Hyperopic group showed an increase of +0.37D in male, and +0.56D in female. For hyperopic group the hypropic refractive errors by CR were +0.37D in male and +0.56D in female higher than the refractive errors by CR. This difference between the results of a preand a post-cycloplegic refraction was more if the patients were younger. This difference between refractive errors by MR and by CR showed the younger the more and the proportions of pseudo-myopia and or latent hyperopia were also higher with younger patents age. The amounts of with-the-rule astigmatism and the oblique astigmatism were increased for the post-cycloplegic refraction in the CR refraction. Simple astigmatism reduced, but there was no difference found in the amount of astigmatism. The prevalence of simple astigmatism reduced, but there was no difference in the amount of astigmatism. Conclusions: The difference between manifest refraction and cycloplegic refraction was more in younger group. The difference of refrative error between by MR and CR increases with ageing decrease. Pseudo-myopia and latent hyperopia was also found in the younger group. Simple astigmatism reduced after cycloplegic refraction, there was no difference found in the amount of astigmatism. The prevalence of simple astigmatism reduced, but there was no difference in the amount of astigmatism.

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17 beta-Estradiol Increases Peak of $\textrm{Ca}^{2+}$ Current in Mouse Early Embryo (에스트로겐이 생쥐 초기배의 $\textrm{Ca}^{2+}$ 전류에 미치는 영향)

  • 강다원;신용원;김은심;홍성근;한재희
    • Journal of Embryo Transfer
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    • v.16 no.2
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    • pp.79-89
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    • 2001
  • Steroid hormones control the expression of many cellular regulators, and a role thor estrogen in mouse oocytes has been well documented. The preovulatory $E_2$increment is generally accepted as the endocrine process regulating induction of in vivo oocyte maturation To address whether the activity of the T-type $Ca^{2+}$ channel is altered by 17 beta-estradiol ( $E_2$), we examined the actions of $E_2$on the calcium channel of mouse oocytes and early embryos. Oocrtes were collected from the oviduct of mice treated with pregnant mare's serum gonadotropin (PMSG) and human choronic gonadotropin (hCG). Whole cell voltage clamp technique and confocal microscopy were used to examine that $E_2$increase intracellular $Ca^{2+}$ concentration ([C $a^{2+}$]$_{i}$ ) via voltage dependent $Ca^{2+}$ channel (VDC) and estrogen receptor (FSR), and $E_2$concentration by the use of radioimmunoassay (RIA) were examined in mouse. The results obtained were as follows: The peak of $Ca^{2+}$ current induced by $E_2$increased 122% to 1.50$\pm$0.03 nA from 1.23$\pm$0.21 nA (n=15) in the presence of 5 mM extracellular $Ca^{2+}$ concentration ([C $a^{2+}$]$_{o}$ ). The increased $Ca^{2+}$ current was temporally associated with $Ca^{2+}$ transients. The intracellular $Ca^{2+}$ level increased 207%~30 s following the addition of 1${\mu}{\textrm}{m}$ $E_2$(relative fluorescence intensity: 836.4$\pm$131.2 for control, n=10, 1736.4$\pm$192.0 in the presence of $E_2$, n=10). $E_2$increased amplitude of $Ca^{2+}$ current and [C $a^{2+}$]$_{i}$ . $E_2$-induced $Ca^{2+}$ current and $E_2$concentration in blood were showed difference on the stage of embryo. These results suggest that $E_2$modulate $Ca^{2+}$ channel to increase $Ca^{2+}$ influx.$Ca^{2+}$ influx.

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A Study of Adjustment for Beginning & Ending Points of Climbing Lanes (오르막차로 시.종점 위치의 보정에 관한 연구)

  • 김상윤;오흥운
    • Journal of Korean Society of Transportation
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    • v.24 no.5 s.91
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    • pp.35-44
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    • 2006
  • Acceleration and deceleration curves have been used for design purposes worldwide. The curve in design level has been regarded as an single deterministic curve to be used for design of climb lanes. It should be noted that the curve was originally made using ideal driving truck and that the curve is applied during design based on the assumption of no difference between ideal and real driving conditions. However. observations show that aged vehicles and lazy behavioring drivers nay make lower performance of vehicles than the ideal performance. The present paper provides the results of truck speeds at climbing lanes then probabilistic variation of acceleration and deceleration corves. For these purposes. a study about identification of vehicle makers, and weights for trucks at freeway toll gates and then observation of vehicle-following speed were performed. The 85%ile results obtained were compared with the deterministic performance curves of 180, 200, and 220 Ib/hp. It was identified that the performance of 85%ile results obtained from vehicle-following-speed observations were lower than one from deterministic performance curves. From these results, it may be concluded that at the beginning Point of climbing lanes additional $16.19{\sim}67.94m$ is necessary and that at the end point of climbing lanes $53.12{\sim}103.24m$ of extension is necessary.

Study on the Manufactures for the Korean Astronomical Instrument

  • Lee, Yong Sam
    • The Bulletin of The Korean Astronomical Society
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    • v.43 no.2
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    • pp.30.1-30.1
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    • 2018
  • 일제 강점기를 지난 후 광복을 맞았지만, 전란의 폐허 속에 개설된 대학의 천문학과의 관측 시설들은 전문한 상태였다. 필자가 학부 재학 중이던 6-70년대까지도 시 시공(時空)의 흐름은 필요한 것을 직접 만들어 사용할 수밖에 없는 시대로 몰아가고 있었다. 당시를 회고 하며 지금까지 걸어 온 "천문기기 제작 연구의 삶"을 회고하고자 한다. 대학 재학 시절 교수님의 도움으로 막스토브 망원경을 제작하고, 40cm 카세그레인 망원경 등 광학계의 원리와 특성연구를 통해 부품 조립을 수행할 수 있었다. 태양 흑점관측을 위한 10cm 굴절 망원경의 투영시설을 고안하여 6개월 동안 관측하였지만. 석사 논문을 위해 광전측광 관측시스템을 제작하여 식쌍성 관측을 수행하였다. 그 결과 한국의 시설로 UBV 광도곡선 완성하여 1975년 가을 천문학회에서 발표하였다. 1976년 2월 국립천문대 천문계산연구실에 발령 받고 역서편찬 업무를 담당하면서 소백산 60cm 망원경 최종 설치를 끝내고, 천문대(현 역삼동 과총회관 빌딩) 옥상에 2m 규모의 목재 돔을 설계 제작하고 일반인들을 위한 대중천문 활동을 시작하였다. 재직 중에 항상 한국의 열악한 천문시설의 상황을 실감하고 20대를 마감하면서 퇴직하여 "한국천문기기 연구소"라는 명칭으로 천체 돔을 설계하고, 돔 제작기계를 개발하였다. 망원경만 보관 중인 국내 4개 대학에 돔을 납품 한 후 연세대학교 천문대의 직경 6m 스텐레스 돔을 제작하였다. 아울러 연세대 천문대 60cm망원경을 설치하면서 이 곳에 입사하여 관측 장비개발 연구와 관측에 전념하게 되었다. 재직 기간 중 대학의 배려로 카나다 국립천문대(DAO) 방문연구원으로 1.8m 망원경으로 식쌍성들의 분광관측을 수행하여 시선속도곡선을 완성하였고, 체류 중에 스텝들과 국내에서 사용할 60cm용 첨단 분광기를 설계하였으나 대학에 재원이 없어 제작을 못한 아쉬움이 남는다. 1989년 2월 충북대학교 천문우주학과에 부임하면서 열악한 상황이지만 교육과 연구 장비로 20cm와 35cm 소형 망원경의 디지털 광전측광시스템으로 간이 천문대를 설치하여 운영하였다. 학과 설립 10 주년(1998년)을 맞아 40cm 망원경과 6m 돔을 설치하여 교내천문대가 완공되었다. 2000년이 되면서 대중 천문활동 을 위해 이동 천문대를 제작하여 4륜 자동차에 견인하여 여러 지역을 찾아 관측과 강연 활동 등 학과의 대중천문 활동의 특성을 살리는 계기를 만들게 되었다. 학과 설립 20주년(2008년)을 맞으면서 충북 진천에 16개 자동분할 개폐식 스릿의 9m 돔 안에 1m 망원경을 원격관측 시설을 완비하여 대학 본부의 기관으로 충북대학교천문대를 개관하고 관측시설을 완비하였다. 우리의 전통적인 세종시대 천문시설은 당대 최대의 시설이지만 당시 유물들이 모두 소실되어 현존하는 것이 하나도 없음은 실로 아쉬움이 큰 것이었다. 누군가는 그 구조, 형태, 원리, 기능, 사용방법 등을 밝히고 복원을 시도해야 할 시급함이 있었다. 문헌을 통해 1991년부터 학부졸업 논문으로 "고천문 의기(儀器) 복원연구" 분야의 발표를 시작하였다. 그 결과를 통해 세종탄신일에 영릉에서 숭모제 행사 후 그 곳에서 수년간 세종시대 고천문의기 한가지씩 작동모델을 복원하여 제막식을 거행하였다, 유물복원 회사 (주)옛기술과 문화 와 함께 팀을 이루어 매년 제작할 종목을 준비하게 되었다. 간의(簡儀)를 복원한 후에는 일성정시의, 소간의, 앙부일구, 정남일구, 석각천문도, 혼천의, 혼상, 각종 해시계 등 매년 지속적으로 복원되어 큰 규모의 야외 전시장이 완성되었다. 작동모델 설계연구팀의 자문과 제작팀과의 팀웍으로 이룬 성과인 것이다. 한번 시작품이 발표된 모델들은 국내 과학관과 박물관, 천문관에서 후속 모델을 설치하였다. 한국천문연구원과 부산 동래읍성 내에 장영실 과학 동산은 간의와 혼상을 비롯한 각종 해시계들을 설치한 큰 규모의 야외 전시장이다. 조선의 명망 높은 유학자들이 인격적인 하늘을 살펴보았던 혼천의와 일만원권에 그려 있는 국보 230호 자명종 혼천시계(일만원권의 그림)의 작동 모델을 제작하였다. 이와 같은 연구 결과들은 석사과정 박사과정을 통하여 더 심층적인 연구들이 발표되었고, 각종 조선(한국)의 천문의기(天文儀器) 연구 자료들은 연구팀들을 통해 중국과 일본 등 해외에서도 발표되었다. 지금까지 복원된 유물들이 완성되기까지는 참여한 많은 연구원들과 제작팀들이 합심하여 각자의 역할을 수행하여 최종 작동모델들이 하나 둘 완성되는 것이었다. 이것은 참으로 보람된 일이었고, 은퇴 후 지금은 재능기부자로서 즐거운 삶을 이어 갈수 있게 되었다.

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An Analysis of Investment Determinants of Korean Accelerators: From the Perspective of Business Model Innovation (국내 액셀러레이터 투자결정요인 중요도 분석: 비즈니스 모델 혁신 관점에서)

  • Jung, Mun-Su;Kim, Eun-Hee
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.5
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    • pp.1-16
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    • 2022
  • Although start-up is a key national strategy to increase national competitiveness and create employment, the survival rate of start-ups has not improved significantly. This is an important reason for the inability to provide timely and appropriate support to startups, which are in the early stages of start-up, due to the unique limitations of existing start-up support institutions and investors. The relatively recent accelerator is attracting attention as a subject of solving the above problems through professional incubation and investment. However, there are only a few empirical studies on investment determinants that affect the survival and success of accelerators, and there is a lack of theoretical evidence. Accordingly, in previous studies, 12 investment determinants were derived from a static, strategic, and dynamic perspective as accelerator investment determinants based on a business model innovation framework. This study subdivided the accelerator investment determinants derived through previous studies into 21 and analyzed the importance and priority of each factor using AHP (Analytic Hierarchy Process) analysis technique for domestic accelerator investment experts. As a result of the analysis, the top factors of importance of accelerator investment determinants were in the order of 'human resources', 'customer and market', 'intellectual resources', and 'entrepreneur's ability to realize opportunities'. It can be seen that the accelerator considers the core competencies of startups to implement solutions as the most important factor when making startup investment decisions. It was also confirmed that accelerators are strategic to create a clear value proposition and differentiated market position based on the core competitiveness of startups, and that the core value delivery method prefers a market-oriented business model and recognizes entrepreneurs's innovation capability is an important factor to realize a business model with limited resources in a rapidly changing market. This study is of academic significance in that it analyzes the importance and priority of accelerator investment determinants through demonstration as a follow-up study on accelerator investment determinants derived based on business model innovation theory that reflects the nature, goals, and major activities of accelerator investment. In addition, it is of practical value as it contributes to revitalizing the domestic startup investment ecosystem by providing accelerators with theoretical grounds for investment decisions and specific information on detailed investment determinants.