• The Korean Journal of Pesticide Science
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• v.2 no.1
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• pp.46-52
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• 1998

The hydrolysis rate of insecticidal buprofezin(IUPAC : tert-butylimino-3-isopropyl-5-phenylperhydro-1,3,5-thiadiazin-4-one) in the range of pH 2.0 and 12.0 have been examined in 15%(v/v) aqueous dioxane at $45^{\circ}C$. The hydrolysis mechanism of buprofezin is proposed from the pH-effect, solvent effect(${\ell}{\gg}m$), thermodynamic parameter(${\Delta}H^{\neq}$=11.12 $Kcal{\cdot}mol^{-1}$ &, ${\Delta}S^{\neq}=5.0e.u.$), rate equation and hydrolysis product, l-isopropyl-3-phenyl urea. General acid catalyzed hydrolysis and specific acid catalyzed($k_{H3O+}$) hydrolysis through $A-S_{E}2$ and A-2(or $A_{AC}2$) reaction mechanism with orbital-control reaction proceed below pH 8.0 and above pH 9.0, the nucleophilic addition-elimination, $Ad_{N}-E$ mechanism via tetrahedral($sp^{3}$) intermediate is initiation by general base catalyzed($k_{H2O}$) reaction. Buprofezin was more stable in alkaline ($k=10^{-8}sec.^{-1}$) than acid solutions from the sigmoid pH-rate profile. And the half-life($t=\frac{1}{2}$) of hydrolysis reaction in neutral aqueous solution(pH 7.0) at $45^{\circ}C$ was about 3 months.

• Korean Journal of Organic Agriculture
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• v.21 no.4
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• pp.725-736
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• 2013

In order to acquire morphological characteristics and genetic characteristics of pathogen that causes anthrax to chestnut, anthrax was separate and identified in Gongju, chungnam chestnut plantation. Antagonistic microorganisms and plant extracts were selected for control of anthrax. Medium maturing variety treatment of 250 dilution fold in field was control at 71.2% and treatment of 500 dilution fold was control at 64.4% and treatment of 1000 dilution fold was control at 40.7%. Storage control value of Jabong in $25^{\circ}C$ after treatment in field is 61.7% at 250 dilution fold, 62.8% at 500 dilution fold, 40.9% at 1000 dilution fold treatment.

• The Korean Journal of Malacology
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• v.30 no.4
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• pp.409-413
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• 2014

Purple-colored shell individuals were discovered among normal green-colored shell individuals in artificial seed of Pacific abalone, Haliotis discus hannai, reared on an ordinary type of diatom and artificial diet. In the present study, factorial mating experiments were designed to clarify the genetic control of the variant (purple type) and normal (green type) of shell color. The parental population of purple type and green type individuals were derived from a single family between a female and male of each type of coloration. The all mating families were reared in same tank for the same breed environment. The individual of 4 type families were distinguished by paternity test using microsatellite DNA. In factorial mating experiments, all individuals offspring of GG (green type female and green type male), GP (green type female and purple type male) and PG (purple type female and green type male) mating types appeared to green type. In only PP (purple type female and purple type male) mating type, all individuals offspring appeared to purple type. The results suggested that the purple shell color is controlled by recessive purple type allele and a dominant green type allele at a single locus.

• Journal of the Korean earth science society
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• v.21 no.1
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• pp.51-58
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• 2000

This study was performed to accumulate database for natural sulfur emissions in the Yellow Sea region of Korea. The atmospheric concentrations of dimethylsulfide(DMS) were measured during two intensive field experiments (April and September 1999) from Duk-Juk Island located in the Yellow Sea. Ship-measurement of DMS was made additionally between Chungdo(China) and Inchun(Korea) across the Yellow Sea during June 1999. The mean(and ISD) of DMS concentrations in Duk-Juk Island during two field campaigns was $24.0{\pm}40.5$(n=40, April) and $61.1{\pm}37.9$ pptv(n=35, September), respectively. The atmospheric DMS measured from ship experiments was generally low and close to the background concentrations in the open sea area. The temporal distributions of DMS concentration were complicated in some sense but comparable to those of ambient meteorological parameters. On the basis of our measurements of atmospheric DMS(and evidence found from previous studies), the sea-to-air flux of DMS in the Yellow Sea is estimated to be about 4Gg S/yr. This amount of natural S emissions is relatively lower than the estimates derived for Cheju Island. Therefore, additional experiments may be desperate to derive more reliable figures for natural sulfur emissions in the Yellow Sea region.

• Herbal Formula Science
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• v.21 no.2
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• pp.144-157
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• 2013

Objectives : The aim of this study was to evaluate the efficacy of Hwangnyeonhaedok-tang (HH) and Geongangbuja-tang (GB) on the plasma hormone level in mice exposed to cold stress. HH and GB are the representative prescriptions of cold and hot property, respectively. Methods : We established cold condition by confining ICR mice to a $4^{\circ}C$ cage for 24 hours, ICR mice were given a HH (100, 300, 1000 mg/kg) or GB (100, 300, 1000 mg/kg) extract orally twice a day for three consecutive days. From the second day, they were given cold stress ($4^{\circ}C$) for twenty four hours. To measure the plasma corticosterone, insulin, thyroxine, epinephrine and norepinephrine levels of mice, their blood samples were collected from cardiac puncture, immediately centrifuged at $4^{\circ}C$. The protein level of HSP70 and JNK was examined using western blot analysis in cortex and hypothalamus. Results : Oral administration of GB more significantly reduced plasma corticosterone level raised by cold stress than HH. Gardeniae Fructus (CJ), the constituent of HH, significantly increased the thyroxine level. Western blot analysis showed that cold stress-induced Heat shock protein 70 (HSP70) expression was increased by HH and GB, HH decreased JNK expression and GB increased JNK expression dose-depently in hypothalamus. Scutellariae Radix (HG), Zingiberis Rhizoma (GG) and Aconiti Tuber (BJ) decreased HSP70 in hypothalamus and GG, BJ decreased HSP70 in cortex as well. Conclusions : These results suggest Geongangbuja-tang (GB) is more effective for ameliorating the stress response caused by cold stress.

• Animal cells and systems
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• v.1 no.2
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• pp.351-354
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• 1997

The distributions of G to A substitution ($G^{-75}{\rightarrow}A$) mutation in the human apolipoprotein A1 (APOAI) gene promoter region and glutathione S-tran-sferase Mu1 (GSTM1) gene deletion were examined in subjects with Korean population. The $G^{-75}{\rightarrow}A$ mutation of APOA1 was genotyped by the polymerase chain reaction (PCR) and subsequent digestion of the PCR product using either Mspl or Mval (n=206). The observed numbers of GG, GA and AA genotypes were 132, 63 and 11, respectively. The allele frequencies of G and A were 0.794 and 0.206, respectively. The GSTM1 gene deletion was simply examined by the PCR amplification (n=106). The observed numbers of null type ($GSTM1^*0/GSTM1^*0$) and positive type were 55 and 51, respectively. The allele frequency of $GSTM1^*0$ was 0.720.

• Journal of Korean Medical classics
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• v.13 no.1
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• pp.102-116
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• 2000

In Cheon Won Gi Dae Ron(天元紀大論), Cheon(大) means Nature, Won(元) means sources, Gi(紀) is Gang Gi(綱紀) that means rules or regulations, so Cheon Won Gi(天元紀) means sources and rules of change that make Nature phenomenons. This volume treats of cause that weather change of Nature caused by, and its general rules, and presents fundamental notions and systems of measuring of 'Five elements' evolutions and Six kinds of natural factors(五運六氣)'. So named Cheon Won Gi Dae Ron(天元紀大論). This article of the research on the Cheon Won Gi Dae Ron(天元紀大論) can be divided into 3 chapters. Chapter 1 presents a theory that the principle of changes of creations' birth, groth and extinction is complished by sympathizing with Hyeong(形) of Ji(地) and Gi(氣) of Cheon(大) by rules of movement of O Un Yum Yang(五運陰陽). Chapter 2 presents theories that Tae Heo(太虛) makes Won Gi(元氣), and this Won Gi(元氣) makes the change of creations' birth, groth and extinction, and movement of O Un(五運) controls creation of nature. And treats of that 'excessive and short(太過不及)' that is made by a quality of Gi(氣) and ups and dons of Hyeong(形) controls weather of year. In Chapter 3, Cheon O Ji Yuk(天五地六) regard six and five as Yong(用). And A Cycle that movment that sympathizing with O Un(五運) and Yuk Gi(六氣) is Il Gi(一氣) as 30 years, and Il Ju(一周) as 60 years. And presents that O Un(五運) and Yuk Gi(六氣) that Gan Ji(干支) control.

• Journal of Haehwa Medicine
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• v.10 no.1
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• pp.221-235
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• 2001

According to the literature study on Nae-gwan and Kongson, reviewing the oriental medical books from Hung-Ti-Nei-Ching $\ll$黃帝內經$\gg$ to recent books and other 35 kinds of literatures, the following results are obtained. 1. The location of Nae-gwan is the superior 2 cun Tae-nung point between Tendon of flexor carpiradials and Tendon of palmaris longus; the location of Kongson is the 1st Metatarsal, medial, dented and posterior 1 cun T'aebaek point. 2. The effects of Nae-gwan are relaxing mind, nutrition of heart, peaceful chest, invigorate vital energy, transmitting triple energy; the effects of Kongson are steadying spleen harmonious stomach clearing away dampness, controlling ch'ung-im, regulating blood. 3. Nae-gwan is often used for circulatory organs disease, digestive organs disease, neuropsychiatry disease; Kongson is often used for digestive organs disease, urinary organs disease, neuropsychiatry disease, therefore, these double points are used for internal disease wholly. 4. The Needle-steadying depth of Nae-gwan is 0.5-1 cun, Kongson is 0.3-2 cun; the Moxibustion dosage of Nae-gwan is 3-7 zhuang, Kongson is 3-5 zhuang. 5. Nae-gwan belongs to pericardium Merdian, Kongson belongs to Spleen Meridian, therefore, these double points are combined in yin Meridian upper and lower sides. These points can be used for treating front body part, such as heart, chest and stomach.

• Journal of Korean Medical classics
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• v.13 no.1
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• pp.233-252
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• 2000

The contents of Yuk Mee Jee Dae Ron(六微旨大論) are as follows. 1. The Yuk Mee Jee Dae Ron(六微旨大論) is one of the Wun Gi Chil Pean(運氣七篇) which are inserted in So Moon(素問) by Wang Bing(王氷) who compile the So Moon(素問) into 24 volume. Wun Gi Chil Pean(運氣七篇) are Chun Won Ki Dae Ron(天元紀大論), O Woon Heng Dae Ron(五運行大論), Yuk Mee Jee Dae Ron(六微旨大論), Gi kuoo Beun Dae Ron(氣交變大論), O Sang Jeong Dae Ron(五常政大論), Yuk Won Jeong KI Dae Ron(六元正紀大論), Gee Gean Yoo Dae Ron(至眞要大論). 2. It prescribe the Sa Chun(司天) Jae Chun(在泉) Jwa Gan Gi(左間氣) Woo Gan Gi(右間氣). 3. It prescribe the Pheo Gi(標氣) Bon Gi(本氣) Juoog Gi(中氣). 4. It prescribe the Youk BO(六步) and the Sheung Gi(承氣). 5. It prescribe the Hamg Hae Sheung Jae(亢害承制) which is feedback control system between each Yuk Gi(六氣). 6. It prescribe the Sae whae(歲會), the Chun Boo(天符) and the Tae Il Chun Boo(太一天符). 7. It prescribe the active time of Yuk gi(六氣) within a year and Sae gi Whae Dong(歲氣會同). 8. It prescribe the Gi Gieo(氣交) which human beings and all the creation are living on. 9. It prescribe the Bo(步) which are composed of Chun Gi(天氣) and Jee Gi(地氣). 10. It prescribe the Duk(德) Wha(化) Yooung(用) bean(變) which are created by quarrel of Yuk Gi(六氣). 11. It prescribe the outbreak of the Sa Gi(邪氣). 12. It prescribe the Sin Gi(神機) and Gi Rib(氣立). 13. It prescribe all the creations existence are up to the Seoung Gang Chul Ip(升降出入). Like the past, the Yuk Mee Jee Dae Ron(六微旨大論) is include very important concep of the medicine. So the study should be continued with minute attention.

• Journal of Korean Medical classics
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• v.13 no.1
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• pp.328-344
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• 2000

YoungChu NonYong(靈樞 論勇)seems to be named as such by its explanation in detail about the brave man who can and the coward who cannot stand pain respectively. In the first chapter, it is considered that the factors of diseases are dependent upon the state of skin and flash. In the second chapter, it is put about the problem of standing pain and not. In the third chapter, about the causes of resulting in brave or unbrave man. And in the fourth chapter, about drunken frenzy(酒悖). More concretely speaking, in the first chapter, it is explained that the factors of pathogenesis are related closely with the state of skin and flash, so to speak, though the outer factors which can arouse diseases should exist, the sensitivity of skin and flash which are the first defense tissue in human body, is more important factor. Undoubtedly, the environmental factors existing in physical nature which surrounds human life, have influenced upon human health, especially in ancient times. But, this chapter exhibits some reflections that ultimately the inner conditions of human body decide the attack of diseases. However, this chapter may have some corruptions for it reveals the contents which are not fit with the headline. In the second chapter, it is written that the sensitivity to pain is not only dependent upon the character of bravery but also upon the thickness of skin, the strength of flesh and the speed of response. In this we evidence that the ancient people had the idea that human pain-feeling is more dependent upon the degree of development of sensory neuron of physical body than one's character of bravery. In the third chapter, ti is described that the differences of physical development mainly influence the differences of the degree of mental bravery. In the fourth chapter, the drunken frenzy is explained. The implication is that as civilization has been growing, the drinking culture has made both in dividual and social health affair. The alcohol has the function of pleasing mind improving the quality of human life but it can also destroy both human body and mind when abused. About the harms like this, this part wams by the examples of drunken man's abnormal behaviors.