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A Clinical Study of Patent Ductus Arteriosus (동맥관 개존증의 임상적 고찰)

  • Jo, Jung-Gu;Park, Geon-Ju;Kim, Gong-Su
    • Journal of Chest Surgery
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    • v.18 no.4
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    • pp.574-581
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    • 1985
  • Surgical treatment for PDA has been pivotal in historical development of surgery for congenital heart disease. A clinical study on 36 cases of operated PDA were performed during period from Aug. 1981 to Jul. 1985 at the Department of Thoracic & Cardiovascular Surgery in Chonbuk University. The following results are obtained. 1. The 8 males and 28 females ranged in age from 2 yrs, to 24 yrs, [mean 11 yrs.] 2. Chief complaints of the patients were dyspnea on exertion in 61%, palpitation in 39%, frequent URI in 12%, and no subjective symptoms in 11%. 3. On auscultation, continuous machinery murmur heard in 94% and systolic in 14%. 4. Radiologic findings of chest P-A showed increased density of pulmonary vascularity in 94%, cardiomegaly in 69%, and within normal limits in 5% of the patients. 5. EKG findings of the patients revealed LVH in 69%, RVH in 6%, BVH in 6%, and within normal limits in 17%. 6. Of the 36 patients, cardiac catheterization was performed in 34 patients. The results showed mean Qp/Qs = 2.25, mean Pp/Ps=0.42, and mean systolic pulmonary arterial pressure=53mmHg. 7. Surgical methods were as followed: The 32 case of ductal ligation and one case of division & suture technique for PDA through the left posterolateral thoracotomy were done. And 2 cases of ductal ligation one suture closure through the pulmonary artery were performed under the cardiopulmonary bypass. 8. Intraoperative complication was ductal rupture with division 8< suture for PDA and transient hoarseness in 1, recanalization in 1, and urethral stricture in 1 case postoperatively. 9. One patient died due to ductal rupture intraoperatively and operative mortality was 2.8%.

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Optimizing the Plasma Deposition Process Parameters of Antistiction Layers Using a DOE (Design of Experiment) (실험 계획법을 이용한 점착방지막용 플라즈마 증착 공정변수의 최적화 연구)

  • Cha Nam-Goo;Park Chang-Hwa;Cho Min-Soo;Park Jin-Goo;Jeong Jun-Ho;Lee Eung-Sug
    • Korean Journal of Materials Research
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    • v.15 no.11
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    • pp.705-710
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    • 2005
  • NIL (nanoimprint lithography) technique has demonstrated a high potential for wafer size definition of nanometer as well as micrometer size patterns. During the replication process by NIL, the stiction between the stamp and the polymer is one of major problems. This stiction problem is moi·e important in small sized patterns. An antistiction layer prevents this stiction ana insures a clean demolding process. In this paper, we were using a TCP (transfer coupled plasma) equipment and $C_4F_8$ as a precursor to make a Teflon-like antistiction layer. This antistiction layer was deposited on a 6 inch silicon wafer to have nanometer scale thicknesses. The thickness of deposited antistiction layer was measured by ellipsometry. To optimize the process factor such as table height (TH), substrate temperature (ST), working pressure (WP) and plasma power (PP), we were using a design of experimental (DOE) method. The table of full factorial arrays was set by the 4 factors and 2 levels. Using this table, experiments were organized to achieve 2 responses such as deposition rate and non-uniformity. It was investigated that the main effects and interaction effects between parameters. Deposition rate was in proportion to table height, working pressure and plasma power. Non-uniformity was in proportion to substrate temperature and working pressure. Using a response optimization, we were able to get the optimized deposition condition at desired deposition rate and an experimental deposition rate showed similar results.

Inhibition of Nitric Oxide Production by Ethyl Digallates Isolated from Galla Rhois in RAW 264.7 Macrophages

  • Park, Pil-Hoon;Hur, Jin;Lee, Dong-Sung;Kim, Youn-Chul;Jeong, Gil-Saeng;Sohn, Dong-Hwan
    • Biomolecules & Therapeutics
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    • v.19 no.4
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    • pp.419-424
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    • 2011
  • Galla Rhois and its components are known to possess anti-infl ammatory properties. In the present study, we prepared equilibrium mixture of ethyl m-digallate and ethyl p-digallate isomers (EDG) from Galla Rhois and examined its effect on nitric oxide (NO) production in murine macrophage cell line. Treatment of RAW264.7 macrophages with EDG signifi cantly inhibited NO production and inducible nitric oxide synthase (iNOS) expression stimulated by LPS, as assessed by Western blot and quantitative RT-PCR analyses. We also demonstrated that EDG treatment led to an increase in heme oxygenase-1 (HO-1) mRNA and protein expression. EDG treatment also enhanced expression level of nuclear factor-erythroid 2-related factor 2 (Nrf2) in nucleus, which is critical for transcriptional induction of HO-1. Treatment with SnPP (tin protoporphyrin IX), a selective HO-1 inhibitor, reversed EDG-mediated inhibition of nitrite production, suggesting that HO-1 plays an important role in the suppression of NO production by EDG. Taken together, these results indicate that EDG isolated from Galla Rhois suppresses LPS-stimulated NO production in RAW 264.7 macrophages via HO-1 induction.

Study of Optimal Process Conditions of 3D Porous Polymer Printing for Personal Safety Products (개인안전 제품을 위한 3 차원 다공성 폴리머 프린팅의 최적화 공정조건에 대한 연구)

  • Yoo, Chan-Ju;Kim, Hyesu;Park, Jun-Han;Yun, Dan-Hee;Shin, Jong-Kuk;Shin, Bo-Sung
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.5
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    • pp.333-339
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    • 2016
  • In this paper, a fundamental experiment regarding the formation of porous 3D structures for personal safety products using 3D PPP (Porous Polymer Printing) was introduced for the first time. The filament was manufactured by mixing PP (Polypropylene) and CBA (Chemical Blowing Agent) with polymer extruder, and the diameter of the filament was approximately 1.75mm. The proposed 3D PPP method, combined with the conventional FDM (Fused Deposition Modeling) procedure, was influenced by process parameters, such as the nozzle temperature, printing speed and CBA density. In order to verify the best processing conditions, the depositing parameters were experimentally investigated for the porous polymer structure. These results provide parameters under which to form a multiple of 3D porous polymer structures, as well as various other 3D structures, and help to improve the mechanical shock absorption for personal safety products.

Capsaicin Ameliorates Cisplatin-Induced Renal Injury through Induction of Heme Oxygenase-1

  • Jung, Sung-Hyun;Kim, Hyung-Jin;Oh, Gi-Su;Shen, AiHua;Lee, Subin;Choe, Seong-Kyu;Park, Raekil;So, Hong-Seob
    • Molecules and Cells
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    • v.37 no.3
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    • pp.234-240
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    • 2014
  • Cisplatin is one of the most potent chemotherapy agents. However, its use is limited due to its toxicity in normal tissues, including the kidney and ear. In particular, nephrotoxicity induced by cisplatin is closely associated with oxidative stress and inflammation. Heme oxygenase-1(HO-1), the rate-limiting enzyme in the heme metabolism, has been implicated in a various cellular processes, such as inflammatory injury and anti-oxidant/oxidant homeostasis. Capsaicin is reported to have therapeutic potential in cisplatin-induced renal failures. However, the mechanisms underlying its protective effects on cisplatin-induced nephrotoxicity remain largely unknown. Herein, we demonstrated that administration of capsaicin ameliorates cisplatin-induced renal dysfunction by assessing the levels of serum creatinine and blood urea nitrogen (BUN) as well as tissue histology. In addition, capsaicin treatment attenuates the expression of inflammatory mediators and oxidative stress markers for renal damage. We also found that capsaicin induces HO-1 expression in kidney tissues and HK-2 cells. Notably, the protective effects of capsaicin were completely abrogated by treatment with either the HO inhibitor ZnPP IX or HO-1 knockdown in HK-2 cells. These results suggest that capsaicin has protective effects against cisplatin-induced renal dysfunction through induction of HO-1 as well as inhibition oxidative stress and inflammation.

A Study on Evaluation to Safety of Fire-proof Safety Helmet (소방 안전모의 안전도 평가에 관한 연구)

  • 한응교;엄기원;박준서;이성우
    • Fire Science and Engineering
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    • v.5 no.3
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    • pp.5-14
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    • 1991
  • Now a days, according that the occurrence of industrial disaster is on the increase, the necessity of protective goods is increasing. Specially estimate of safety helmet for protect of head is very important. On this, in this paper, amplification ratio and natural frequencies of fire safety helmet and general safety helmet are estimated by falling impect test and frequency analysis. Also. trend of damping is estimated by using these test results. And we know that the fire safety helmet is more safe than general safety helmet for protect of head.

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Gas Composition within Kimchi Package as Influenced by Temperature and Seasonal Factor (온도 및 계절요인에 따른 포장 김치의 기체조성 변화)

  • Hong, Seok-In;Lee, Myung-Ki;Park, Wan-Soo
    • Korean Journal of Food Science and Technology
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    • v.32 no.6
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    • pp.1326-1330
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    • 2000
  • Kimchi, made from seasonal baechu (Chinese cabbage), was sealed in PP trays with a Nylon/CPP lid film and stored at various temperatures (0, 10, $20^{\circ}C$) to investigate the feasibility of detecting its fermentation degree by measuring gas composition inside the packages. The gas composition inside the kimchi package continuously changed due to $CO_2$ evolution during fermentation. Regardless of temperature, the fermentative gas accumulation in the package caused $CO_2$ concentration to increase by two-stepwise pattern, but $O_2$ concentration to decrease exponentially. As $CO_2$ concentration increased secondarily, the pH values of kimchi decreased proportionally (r>0.968). The production of $CO_2$ during kimchi fermentation was stimulated at higher temperatures and affected by seasonal factor. Kimchi made from winter baechu produced more fermentative gas than that from summer baechu. It was suggested that the changes in $CO_2$ concentration could be used as a characteristic index for indicating the fermentation course of packaged kimchi products.

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SOME REMARKS ON PRIMAL IDEALS

  • Kim, Joong-Ho
    • Bulletin of the Korean Mathematical Society
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    • v.30 no.1
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    • pp.71-77
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    • 1993
  • Every ring considered in the paper will be assumed to be commutative and have a unit element. An ideal A of a ring R will be called primal if the elements of R which are zero divisors modulo A, form an ideal of R, say pp. If A is a primal ideal of R, P is called the adjoint ideal of A. The adjoint ideal of a primal ideal is prime [2]. The definition of primal ideals may also be formulated as follows: An ideal A of a ring R is primal if in the residue class ring R/A the zero divisors form an ideal of R/A. If Q is a primary idel of a ring R then every zero divisor of R/Q is nilpotent; therefore, Q is a primal ideal of R. That a primal ideal need not be primary, is shown by an example in [2]. Let R[X], and R[[X]] denote the polynomial ring and formal power series ring in an indeterminate X over a ring R, respectively. Let S be a multiplicative system in a ring R and S$^{-1}$ R the quotient ring of R. Let Q be a P-primary ideal of a ring R. Then Q[X] is a P[X]-primary ideal of R[X], and S$^{-1}$ Q is a S$^{-1}$ P-primary ideal of a ring S$^{-1}$ R if S.cap.P=.phi., and Q[[X]] is a P[[X]]-primary ideal of R[[X]] if R is Noetherian [1]. We search for analogous results when primary ideals are replaced with primal ideals. To show an ideal A of a ring R to be primal, it sufficies to show that a-b is a zero divisor modulo A whenever a and b are zero divisors modulo A.

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Overview and Recent Development of Recycling Waste Refrigerators (폐(廢) 냉장고(冷藏庫) 재활용(再活用) 현황(現況)과 기술(技術) 전망(展望))

  • Yang, Hyunseok;Kim, Geon-Hong;Kong, Man-Sik;Park, Kiejin;Lee, Gwang Weon;Kim, Bo Saeng
    • Resources Recycling
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    • v.22 no.4
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    • pp.70-80
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    • 2013
  • Waste refrigerator is the most large amount of item being recycled and the recycling process is the most complicated in WEEE (Waste Electrical and Electronic Equipment) because refrigerator is biggest product and consists of various parts and materials such as ferrous, non-ferrous, and plastics. Recently, recycling process of waste refrigerator has been being more complex since large capacity 2 door refrigerators and standing Kimchi refrigerators with various material are distributed on custom market. In addition, recycling of valuable resource from waste refrigerator is mandatory by WEEEs recycling legislation; therefore, high efficiency recycling enough for economic and environment-friendly recovery of valuable resource through present technical situation analysis and comparison of recycling technologies of waste refrigerator with advanced country.

Synthesis and Reaction Chemistry of Some Ferrocene-Containing Chelate Ligands with Dirhodium Acetate: X-ray Crystal Structure of $(\eta^1-(S,R)-CPFA)_2Rh_2(OAc)_4$

  • Kim, Eun-Jin;Kim, Tae-Jeong
    • Bulletin of the Korean Chemical Society
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    • v.15 no.11
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    • pp.990-996
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    • 1994
  • New ferrocene-based chelate amines, $Fe[C_5H_4CH(Me)NMe_2]_2\;(3), \;Fe[C_5H-3(CH(Me)NMe_2)(PPh_2)-1,2]_2\;(4),\;(C_5H_5)Fe(C_5H_3(CH_2NMe_2)(CH(CN)NMe_2-1,2)\;(6),\;and\;(C_5H_5)Fe(C_5H_3(CH_2NMe_2)(CH(Me)NMe_2-1,2)$ (7) have been prepared. The reaction and the coordination chemistry of 4 and other related compounds (S,R)-(1-N,N-dimethylaminoethyl)-2-dicyclohexylphosphino)ferrocene (CPFA) and 1,1'-bis-(diphenylphosphino)ferrocene (BPPF) with $Rh_2(OAc)_4(MeOH)_2$ were investigated. The reaction of the chiral ligand (S,R)-CPFA forms a complex of the type (${\eta}^1$-(S,R)-CPFA-P)$_2Rh_2(OAc)_4$ (8) in which the ligand is coordinated to both rhodium centers in a monodentate fashion through phosphorus. In contrast, the bisphosphine analogues such as BPPF and 4 afford chelate complexes of the type (${\eta}^2-PP)Rh_2(OAc)_4$ (9 & 10) where both ligands act as a chelate bidentate to a single rhodium atom. All these complexes were characterized by microanalytical and spectroscopic techniques. In one case, the structure of 8 was determined by X-ray crystallography. Crystals are monoclinic, space group C2 (No. 5), with a=26.389 (3), b=12.942 (1), c=11.825 (1) A, ${\beta}$=111.22(1)$^{\circ}$, V=3964.7 (8) $A^3$, Z=4, and $D_{calc}$=1.58 g $cm^{-3}$. Two Rh(II) centers are bridged by four $AcO^-$ groups in the ${\eta}^1$ : ${\eta}^1$ mode across a Rh-Rh single bond, and octahedral coordination at Rh(1) and Rh(1') is completed by axially coordinating (S,R)-CPFA and a briding $AcO^-$, respectively.