• Title/Summary/Keyword: [pp]

Search Result 2,654, Processing Time 0.027 seconds

Efficacy of Electroacupuncture using an Insulated Needle in Adults with Abdominal Obesity: A Pilot Study

  • Oh, Seo Young;Lee, Hyun;Yun, Gee Won;Kang, Jae Hui
    • Journal of Acupuncture Research
    • /
    • v.34 no.2
    • /
    • pp.49-59
    • /
    • 2017
  • Objectives : This study evaluated the efficacy of electroacupuncture therapy using an insulated needle in adults with abdominal obesity. Methods : This study was a randomized, double-blind, parallel-designed pilot trial. Sixteen participants eligible according to the inclusion and exclusion criteria were randomly divided into an insulated needle group and a control group. Insulated or common needles were inserted at acupoints located on the abdomen (CV12, CV6, ST25, ST27, SP15) and were electrically stimulated for 30 minutes (16 Hz, within tolerable strength). A total of 10 sessions of treatment were performed twice per week for 5 weeks. All participants were requested to maintain their usual diet and lifestyle. The outcome measures were waist circumference (WC), waist-to-hip ratio (WHR), and abdominal computed tomography (CT) of the total fat area (TFA), subcutaneous fat area (SFA), and visceral fat area (VFA). Results : A total of 12 participants divided into the insulated needle group (n = 5) and the control group (n = 7; common needle) were treated for 10 sessions and analyzed per-protocol (PP). WC decreased significantly after 10 sessions in both groups. The WC, TFA, SFA, and VFA of abdominal CT in the insulated needle group decreased more than in the control group; however, there were no significant differences in any parameter between the insulated needle group and the control group. Patients in the insulated needle group were more strongly stimulated with electrical stimulation than patients in the control group. Conclusion : Electroacupuncture using insulated needles in adults with abdominal obesity might be a more effective treatment than common needles. Additional studies are required to compensate for the limitations of this pilot study and to verify the results and efficacy.

Precise Orbit Estimation of GPS using GIPSY-OASIS (GIPSY-OASIS기반 GPS 정밀 궤도 추정)

  • Ha, Jihyun;Chun, Sebum;Park, Kwan-Dong
    • Journal of Advanced Navigation Technology
    • /
    • v.23 no.6
    • /
    • pp.535-541
    • /
    • 2019
  • In this paper, scripts for estimating the reference orbits of navigation satellites were developed and their performance was analyzed as a preliminary study for the development of the Korean GPS precise orbit determination technology. The JPL Flinn AC's data processing strategy was applied and Linux-based scripts were developed using GIPSY-OASIS. For the analysis of the accuracy of the estimated reference orbit, the precise orbit provided by the international GNSS data center was used as the truth. As a result, estimated satellite coordinates showed almost exactly same patterns and trends with the reference precise orbits, and their differences are in the range of ±2 cm. The average error between the two orbits was less than 1 cm in the 3D direction, while the standard deviation was also at 1 cm. From these, we found that the developed scripts have excellent performance in precise orbit determination.

A Method for Estimating Retransmission Fee for Terrestrial Broadcasting Channels between Terrestrial Television Systems and Cable TV System Operators (지상파방송과 케이블방송 간에 지상파채널 재송신 대가 산정방안)

  • Moon, Myung-Sok;Lee, Song-Hee;Choi, Seong-Jhin
    • Journal of Broadcast Engineering
    • /
    • v.21 no.5
    • /
    • pp.689-703
    • /
    • 2016
  • A dispute over price for retransmitting terrestrial channels between Terrestrial Television Systems and Cable TV System Operator(SO)s has been underway up to now since 2007 and expected to last unless there is a measure of extraordinary countermeasures. Thus, in this paper, we present a scheme for calculating the reasonable price on retransmitting terrestrial channels. Re-transmission price calculation scheme is presented in two ways. One is to calculate the price for the extent to which Terrestrial broadcasters and Cable broadcasters contribute, and the other is to calculate the price for terrestrial channels retransmitted by applying the method of Cable TV PP program fee basis. In addition, on profit-sharing scheme and criteria for program fee we present two ways of subscription, which are flat sum system and fixed rate system.

Identification, Characterization and Phylogenic Analysis of Conserved Genes within the p74 Gene Region of Choristoneura fumiferana Granulovirus Genome

  • Rashidan, Kianoush Khajeh;Nassoury, Nasha;Giannopoulos, Paresa N.;Mauffette, Yves;Guertin, Claude
    • BMB Reports
    • /
    • v.37 no.6
    • /
    • pp.700-708
    • /
    • 2004
  • The genes located within the p74 gene region of the Choristoneura fumiferana granulovirus (ChfuGV) were identified by sequencing an 8.9 kb BamHI restriction fragment on the ChfuGV genome. The global guanine-cytosine (GC) content of this region of the genome was 33.02%. This paper presents the ORFs within the p74 gene region along with their transcriptional orientations. This region contains a total of 15 open reading frames (ORFs). Among those, 8 ORFs were found to be homologues to the baculoviral ORFs: Cf-i-p , Cf-vi, Cf-vii, Cf-viii (ubiquitin), Cf-xi (pp31), Cf-xii (lef-11), Cf-xiii (sod) and Cf-xv-p (p74). To date, no specific function has been assigned to the ORFs: Cf-i, Cf-ii, Cf-iii, Cf-iv, Cf-v, Cf-vi, Cf-vii, Cf-ix and Cf-x. The most noticeable ORFs located in this region of the ChfuGV genome were ubiquitin, lef-11, sod, fibrillin and p74. The phylogenetic trees (constructed using conceptual products of major conserved ORFs) and gene arrangement in this region were used to further examine the classification of the members of the granulovirus genus. Comparative studies demonstrated that ChfuGV along with the Cydia pomonella granulovirus (CpGV), Phthorimaea operculella granulovirus (PhopGV), Adoxophyes orana granulovirus (AoGV) and Cryptophlebia leucotreta granulovirus (ClGV) share a high degree of amino acids sequence and gene arrangement preservation within the studied region. These results support a previous report, which classified a granuloviruses into 2 distinct groups: Group I: ChfuGV, CpGV, PhopGV and AoGV and Group II: Xestia c-nigrum granulovirus (XcGV) and Plutella xylostella granulovirus (PxGV). The phylogenetic and gene arrangement studies also placed ClGV as a novel member of the Group I granuloviruses.

Role of Retinoic Acid in Spontaneous Apoptosis of Human Neutrophils

  • Yang, Eun-Ju;Lee, Ji-Sook;Kim, Dong-Hee;Min, Bok-Kee;Hyun, Sung-Hee;Kim, In-Sik
    • Biomedical Science Letters
    • /
    • v.13 no.4
    • /
    • pp.279-285
    • /
    • 2007
  • Although retinoic acid has been known as either anti-inflammatory or pro-inflammatory molecule, depending on the cell type, its exact role in mature human neutrophils has not been fully explored. In this study, we investigate the effects of retinoic acid on neutrophil apoptosis and the associated mechanism and found that 9-cis retinoic acid (9CRA) significantly inhibits the spontaneous apoptosis of neutrophils. Its effect is increased by co-treatment with $TNF-\alpha$ (P<0.05). The 9CRA-induced inhibition is blocked by the following enzyme inhibitors: Ly 294002, phosphoinoside (PI)-3 kinase inhibitor, U73122, a phospholipase C (PLC) inhibitor, PP2, Src family protein inhibitor, SB202190, p38 MAPK inhibitor, and BAY-11-7085, NF-kB inhibitor. This study also demonstrates that all-trans retinoic acid suppresses spontaneous apoptosis, similar to the mechanism of inhibition exhibited by 9CRA. Phosphorylation of p38 MAPK decreases by 9CRA treatment. $Ik-B{\alpha}$ is degraded until 30 minutes after a time-dependent 9CRA treatment, but degradation can be inhibited by Ly 294002. These results indicate that 9CRA decreases p38 MAPK activation, induces NF-kB activation via PI-3 kinase, and also blocks cleavage of caspase 3. As these findings suggest, 9CRA has a molecular mechanism which may help pro-inflammatory response by blocking neutrophil apoptosis.

  • PDF

Curcumin ameliorates TNF-α-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells

  • Youn, Gi Soo;Kwon, Dong-Joo;Ju, Sung Mi;Choi, Soo Young;Park, Jinseu
    • BMB Reports
    • /
    • v.46 no.8
    • /
    • pp.410-415
    • /
    • 2013
  • Adhesion molecules such as ICAM-1 are important in the infiltration of leukocytes into the site of inflammation. In this study, we investigated the inhibitory effects of curcumin on ICAM-1 expression and monocyte adhesiveness as well as its underlying action mechanism in the TNF-${\alpha}$-stimulated keratinocytes. Curcumin induced expression of heme oxygenase-1 (HO-1) in the human keratinocyte cell line HaCaT. In addition, curcumin induced Nrf2 activation in dose- and time-dependent manners in the HaCaT cells. Curcumin suppressed TNF-${\alpha}$-induced ICAM-1 expression and subsequent monocyte adhesion, which were reversed by the addition of tin protoporphyrin IX (SnPP), a specific inhibitor of HO-1, or HO-1 knockdown using siRNA. Furthermore, Nrf2 knockdown using siRNA reversed the inhibitory effect of curcumin on the TNF-${\alpha}$-induced ICAM-1 expression and adhesion of monocytes to keratinocytes. These results suggest that curcumin may exert its anti-inflammatory activity by suppressing the TNF-${\alpha}$-induced ICAM-1 expression and subsequent monocyte adhesion via expression of HO-1 in the keratinocytes.

Culture Condition and Inoculum Volume of Liquid Spawn on the Bottled Cultivation of Agrocybe cylindracea (버들송이(Agrocybe cylindracea)의 액체종균 배양조건과 접종량)

  • Cheong, Jong-Chun;Hong, In-Pyo;Jang, Kab-Yeul;Park, Jeong-Sik
    • The Korean Journal of Mycology
    • /
    • v.31 no.2
    • /
    • pp.94-97
    • /
    • 2003
  • In order to shorten cultivation periods of Agrocybe cylindracea, liquid spawn was used in place of sawdust spawn. Optimum culture condition of liquid spawn was PSB (potato extract sugar broth) medium, $25^{\circ}C$ temperature and pH 7.0. And, optimum inoculum volume was $10{\sim}15ml$. Two grams per liter of dry weight of the fungal mycelia were obtained with 10l of culture bottle with liquid spawn after 10 days. In 850 ml-bottle of sawdust media, cultivation period using liquid spawn (30 days) was five days shorter compared with the cultivation period in sawdust spawn (35 days). Also, complete growth of sawdust media was increased to 92% (liquid spawn) from 75% (sawdust spawn) and yield of fruiting bodies was increased to about 10%.

Synthesis of Aminated Hollow PP-g-GMA Fibrous Ion-Exchanger for Separation of Urokinase (유로키나제 분리를 위한 아민화 HPP-g-GMA 중공사 이온교환체의 합성에 관한 연구)

  • 황택성;이진혁
    • Polymer(Korea)
    • /
    • v.26 no.2
    • /
    • pp.160-167
    • /
    • 2002
  • We synthesized HPP-g-GMA copolymer using pre-irradiation method by E-beam and aminated HPP-g-GMA using amination reaction. Degree of grafting increased with increasing GMA monomer concentration and showed the maximum value of 130% at 1.46 M of GMA. The degree of amination increased with increasing the degree of grafting. When the degree of grafting was 100%, degree of amination showed the maximum value of 37.4%. The ion exchange capacity of aminated HPP-g-GMA was about 3.78 meq/g, and it showed remarkable adsorption ability of hollow fiber ion exchanger. Through the BET analysis, the surface area of aminated HPP-g-GMA was 54.83 $\m^2/g$ and the mean pore size was $26\AA$. These showed the decrease of surface area and the slight increase of the mean pore size. SEM results show that the thickness of fiber increased after the step of reaction and there pore blocking phenomena was not observed. The aminated HPP-g-GMA was synthesized successfully and found to be suitable for the adsorption and separation of anion.

Oak Mushroom Cultivation on Larch(Larix leptolepis Gorden) sawdust and its economic efficiency (낙엽송 톱밥을 이용(利用)한 표고버섯 재배(栽培)와 경제성)

  • Min, Du Sik
    • Journal of Korean Society of Forest Science
    • /
    • v.83 no.4
    • /
    • pp.512-520
    • /
    • 1994
  • To enhance the utilization of Larch(Larix leptolepis Gorden) wood, the sawdusts were tested as cultivating media for Lentinus edodes(Mori 290) by varying the composition of the media. The economic efficiency for producing mushrooms from larch sawdusts was evaluated. The results are as follows. 1. Larch sawdust was as much efficient as oak sawdust in the growth of the mycelia and production of good quality of oak mushrooms. 2. The mushrooms were able to be harvested starting six months after beginning the cultivation. No differences were found among the qualities of the mushrooms produced by various treatments. 3. The contents of lignin(28.6-28.7%) in the fresh sawdust of larchwood are higher than those in the residues of the used media(18.2%). But lignin content of 1% NaOH extracts(30.4-34.4%) in fresh sawdust of larch was lower than those in the residues(68.0%). 4. The production of mushroom was relatively high to be 29.7-31.5%(760-780g.)/2.5kg pack) of mushroom weight. The net profit estimated was 1,475Won per pack.

  • PDF

A Study on the Expectation Change of Economic Subjects in Stock Market - Focusing on Effect of Change in Money Supply Before and After a Currency Crisis- (주식시장에 대한 경제주체들의 기대 변화에 관한 연구 - 외환위기 전후의 통화량 변화의 영향을 중심으로 -)

  • Kim, Ji-Yeol
    • The Korean Journal of Financial Management
    • /
    • v.21 no.1
    • /
    • pp.125-148
    • /
    • 2004
  • This paper deals with the relationship between money supply and the stock market. However, unlike past works, it has employed a rational expectation hypothesis and an efficient market hypothesis drawn from new classical macroeconomics and new Keynesian macro-economics, respectively. Accordingly, hypothesis 1 states that if economic subjects have rational expectation, they will immediately respond to a change in money supply. On the other hand, hypothesis 2 supposes that the expectation of economic subjects has changed after the currency crisis. This paper has first identified unit root by using the augmented Dickey-Fuller test and the Phillips-Perron test, then testing both hypotheses by employing the Johansen Procedure and vector error correction model for the periods before and after a currency crisis.

  • PDF