• Title/Summary/Keyword: [ph]

Search Result 1,898, Processing Time 0.027 seconds

Multifunctional Probiotic and Functional Properties of Lactiplantibacillus plantarum LRCC5314, Isolated from Kimchi

  • Yoon, Seokmin;Cho, Hyeokjun;Nam, Yohan;Park, Miri;Lim, Ahyoung;Kim, Jong-Hwa;Park, Jaewoong;Kim, Wonyong
    • Journal of Microbiology and Biotechnology
    • /
    • v.32 no.1
    • /
    • pp.72-80
    • /
    • 2022
  • In this study, the survival capacity (acid and bile salt tolerance, and adhesion to gut epithelial cells) and probiotic properties (enzyme activity-inhibition and anti-inflammatory activities, inhibition of adipogenesis, and stress hormone level reduction) of Lactiplantibacillus plantarum LRCC5314, isolated from kimchi (Korean traditional fermented cabbage), were investigated. LRCC5314 exhibited very stable survival at ph 2.0 and in 0.2% bile acid with 89.9% adhesion to Caco-2 intestinal epithelial cells after treatment for 2 h. LRCC5314 also inhibited the activities of α-amylase and α-glucosidase, which are involved in elevating postprandial blood glucose levels, by approximately 72.9% and 51.2%, respectively. Treatment of lipopolysaccharide (LPS)-stimulated RAW 264.7 cells with the LRCC5314 lysate decreased the levels of the inflammatory factors nitric oxide, tumor necrosis factor (TNF-α), interleukin (IL)-1β, and interferon-γ by 88.5%, 49.3%, 97.2%, and 99.8%, respectively, relative to those of the cells treated with LPS alone. LRCC5314 also inhibited adipogenesis in differentiating preadipocytes (3T3-L1 cells), showing a 14.7% decrease in lipid droplet levels and a 74.0% decrease in triglyceride levels, as well as distinct reductions in the mRNA expression levels of adiponectin, FAS, PPAR/γ, C/EBPα, TNF-α, and IL-6. Moreover, LRCC5314 reduced the level of cortisol, a hormone with important effect on stress, by approximately 35.6% in H295R cells. L. plantarum LRCC5314 is identified as a new probiotic with excellent in vitro multifunctional properties. Subsequent in vivo studies may further demonstrate its potential as a functional food or pharmabiotic.

DO THE OBSERVED RELATIONS OF THE GLOBAL SEISMIC PARAMETERS DEPEND ON THE MAGNETIC ACTIVITY LEVEL?

  • Kim, Ki-Beom;Chang, Heon-Young
    • Journal of The Korean Astronomical Society
    • /
    • v.54 no.4
    • /
    • pp.121-128
    • /
    • 2021
  • It has been known that the global asteroseismic parameters as well as the stellar acoustic mode parameters vary with stellar magnetic activity. Some solar-like stars whose variations are thought to be induced by magnetic activity, however, show mode frequencies changing with different magnitude and phase unlike what is expected for the Sun. Therefore, it is of great importance to find out whether expected relations are consistently manifested regardless of the phase of the stellar magnetic cycle, in the sense that observations are apt to cover a part of a complete cycle of stellar magnetic activity unless observations span several decades. Here, we explore whether the observed relations of the global seismic parameters hold good regardless of the phase of the stellar magnetic cycle, even if observations only cover a part of the stellar magnetic cycle. For this purpose, by analyzing photometric Sun-as-a-star data from 1996 to 2019 covering solar cycles 23 and 24, we compare correlations of the global asteroseismic parameters and magnetic proxies for four separate intervals of the solar cycle: solar minima ±2 years, solar minima +4 years, solar maxima ±2 years, and solar maxima +4 years. We have found that the photometric magnetic activity proxy, Sph, is an effective proxy for the solar magnetic activity regardless of the phase of the solar cycle. The amplitude of the mode envelope correlates negatively with the solar magnetic activity regardless of the phase of the solar cycle. However, relations between the central frequency of the envelope and the envelope width are vulnerable to the phase of the stellar magnetic cycle.

Biological Characterization of Paenibacillus polymyxa JE201 with Antifungal Activity Against Fungal Leaf Spot Disease of Aster scaber (취나물 점무늬병을 억제하는 Paenibacillus polymyxa JE201의 생물학적 특성)

  • Ahn, Seong-Ho;Kim, Dayeon;Park, Byeng-Yong;Han, Ji Hee;Lee, Sang-Yeop
    • Korean Journal of Organic Agriculture
    • /
    • v.29 no.2
    • /
    • pp.257-273
    • /
    • 2021
  • Koreans consume cham-chwi (Aster scaber thunb.) as a common vegetable in a meal because of its bitter taste and rich flavor. In addition, it is the crop with the most residual pesticides detected in the last five years. Among the detected pesticides, the most common was azoxystrobin, which is a drug used primarily to prevent the leaf spot disease of A. scaber caused by Septoria sp.. We isolated the microorganisms that antifungal activity against Septoria sp.. The optimum incubation conditions (temperature, pH and growth medium) were examined for the growth of the isolates. Additionally, cellulase and protease activity and siderophore production ability were also examined. According to 16S rRNA sequencing of the isolate was affiliated to Paenibacillus polymyxa JE201. Largest inhibition zone measuring up to 9.2 mm was observed for P. polymyxa JE201 after 7 days of inoculation. P. polymyxa JE201 strain showed antifungal activity against various fungal phytopathogens Altanaria sp., Botrytis cinerea, Colletotrichum acutatum, Fusarium oxysporum, Phytophthora capsici, Ph. drechesleria, Rhizoctonia solani and Stemphylium sp.. Based on these observations, P. polymyxa. JE201 can be used as a promising biocontrol agent for preventing the leaf spot disease and other phytopathogens.

A Study on Developing the Adolescent Anger Provocation Scale(AAPS) for Korean Adolescents (한국 청소년 분노유발요인 척도개발연구)

  • Lee, Jee-Sook
    • The Journal of the Korea Contents Association
    • /
    • v.22 no.3
    • /
    • pp.261-272
    • /
    • 2022
  • The aim of the study is to develop the Adolescent Anger Provocation Scale(AAPS) for Korean adolescents. In order to develop the scale, two research processes were conducted. First, a total of 130 items were derived from various related research. After analyzing 130 items by a research team(2 related field professors and 2 Ph.D. students), a total of 54 items reconstructed based on redundancy, cultural relevancy, and appropriateness. Second, a survey was administered among 252 Korean adolescents. After analyzing an exploratory factor analysis, 12 items of poor factor loading were deleted. Thus, seven factors and 42 items were extracted. Seven factors were as follows: (1) threat to self-esteem, (2) uncontrollable situations, (3) violation of personal property, (4) incidents associated with rejection, (5) violation of regulation or rules, (6) disrespectful treatment, (7) unfair treatment due to age. The internal consistency and convergence validity of the scale were supported. The results of confirmatory factor analysis were also reported. In addition, study limitations and recommendations of future research were discussed.

Exploring Support Vector Machine Learning for Cloud Computing Workload Prediction

  • ALOUFI, OMAR
    • International Journal of Computer Science & Network Security
    • /
    • v.22 no.10
    • /
    • pp.374-388
    • /
    • 2022
  • Cloud computing has been one of the most critical technology in the last few decades. It has been invented for several purposes as an example meeting the user requirements and is to satisfy the needs of the user in simple ways. Since cloud computing has been invented, it had followed the traditional approaches in elasticity, which is the key characteristic of cloud computing. Elasticity is that feature in cloud computing which is seeking to meet the needs of the user's with no interruption at run time. There are traditional approaches to do elasticity which have been conducted for several years and have been done with different modelling of mathematical. Even though mathematical modellings have done a forward step in meeting the user's needs, there is still a lack in the optimisation of elasticity. To optimise the elasticity in the cloud, it could be better to benefit of Machine Learning algorithms to predict upcoming workloads and assign them to the scheduling algorithm which would achieve an excellent provision of the cloud services and would improve the Quality of Service (QoS) and save power consumption. Therefore, this paper aims to investigate the use of machine learning techniques in order to predict the workload of Physical Hosts (PH) on the cloud and their energy consumption. The environment of the cloud will be the school of computing cloud testbed (SoC) which will host the experiments. The experiments will take on real applications with different behaviours, by changing workloads over time. The results of the experiments demonstrate that our machine learning techniques used in scheduling algorithm is able to predict the workload of physical hosts (CPU utilisation) and that would contribute to reducing power consumption by scheduling the upcoming virtual machines to the lowest CPU utilisation in the environment of physical hosts. Additionally, there are a number of tools, which are used and explored in this paper, such as the WEKA tool to train the real data to explore Machine learning algorithms and the Zabbix tool to monitor the power consumption before and after scheduling the virtual machines to physical hosts. Moreover, the methodology of the paper is the agile approach that helps us in achieving our solution and managing our paper effectively.

Research Trends of Young Children's Parent Education Programs Children in South Korea from 2001 to 2020 (영유아 부모교육 프로그램 연구의 2001-2020년간의 국내 연구 동향)

  • Gilsun Han;Eunjoo Kang
    • Korean Journal of Childcare and Education
    • /
    • v.19 no.1
    • /
    • pp.111-126
    • /
    • 2023
  • Objective: The purpose of the current research is to collect basic data to diagnose the current status and to foresee the future research trends of young children's parent education programs published in South Korea from 2001 to 2020. Methods: Data collection was made out of RISS of Korea. Excel 2016 was used to categorize 210 finally filtered and collected data which included academic journal articles, MA/PhD dissertations, and funded research reports according to analysis criteria by publication year/5-year-term, research theme, research method, and researchers' academic area. Results: Annual/5-year-term analysis shows increasing trends of parent education programs for young children. Quantitative research was the most frequently implemented method, followed by literature reviews, qualitative research, and mixed research method in order. In research theme, parent-competency reinforcement program was the most frequently implemented theme followed by parent education, socio-emotional issue, special education for young children with special needs, family support, early childhood sex education, and program analysis in order. Education area showed the most active participation in parent education program for young children in comparing with other academic areas in research field. Conclusion/Implications: Research trends of young children's parent education programs showed steady increase in their amount, frequency, and diversity as well. Minority parents need more attentions for providing the next young generation's educational equality. Parent programs during COVID-19 need to gain more research attentions as well as care-giving grandparents, social workers, and public health care helpers in child caring service areas in order to alleviate low-birth rate.

Money as a Polycontextual Value and Means of Self-Identification of a Modern Person: Traditional vs Virtual

  • S. Khrypko;Qi Yang;M. Kozlovets;I. Chornomordenko;M. Kolinko ;V. Havronenko;O. Lobanchuk;Н. Salo
    • International Journal of Computer Science & Network Security
    • /
    • v.23 no.2
    • /
    • pp.1-12
    • /
    • 2023
  • The article examines the axiological psycho-philosophical understanding of the phenomenon of money and its value role in modern society. The traditional and virtual context of the representation of the money phenomenon is considered.Following the ideas of G. Simmel, the authors consider money not only as a purely economic, but also a psycho-philosophical, cultural and social phenomenon. Money appears as a result of cultural development of the world and gradually forms a monetary culture as a space of economic and social interaction of people. Under the influence of the monetary culture of one or another historical period, the character of a person's economic activity, values and life orientations are formed. Modern money culture is often called financial civilization. Peculiarities of modern monetary culture are studied, its main features and problems are determined in the article. The problem of the peculiarities of the constructive and destructive attitude of the individual towards money is identified; a psycho-philosophical and cultural-identification typology of people is described, which is based on clinical observations and interpreted through the prism of psychoanalytic theory. The concept of money is highlighted from the standpoint of a social-psychological approach. The theoretical foundations of money's influence on the decision-making process and human behavior are also revealed.

Investigation with $^{32}P$ on the effects of phosphate and lime under difference soil fertility in soybean production ($^{32}P$를 이용한 대두의 토양별 인산 및 석회 시용량에 관한 연구)

  • Jung, S.H.;Ro, C.J.;Park, K.Y.
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.24 no.1
    • /
    • pp.84-91
    • /
    • 1979
  • This experiment was earned out with $^32$P labeled phosphate and lime to determine the optimum amount of phosphate and lime fertilizers to soybean under various types of soil. The determination was made by the index of absorption of phosphate by soybean plants. The index of phosphate was 854 (mg/100g) in non matured soil. Due to the capability of neutralization of calcium the PH of the soil was raised to 6.5. The highest yield was obtained in matured soil at the index of phosphate absorption at 5% level. The degree of contribution of phosphate in. non matured soil showed slightly higher tendancy than that in matured soil.

  • PDF

Reaction Kinetics and Absorption Property of Low Molecular Weight Endo-glucanase Component of Cellulase (Cellulase 성분 중 Endo-gluanasec의 반응 및 흡착특성에 관한 연구)

  • Ryu, W.S.;Ryu, Dewey D.Y.
    • Microbiology and Biotechnology Letters
    • /
    • v.8 no.1
    • /
    • pp.41-46
    • /
    • 1980
  • Low molecular weight endo-glucanase was partially purified from cellulase complex using Sephadex G-100 gel chromatography. Biochemical properties of the purified component was investigated. Optimum pH and temperature determined were 6.0 and 5$0^{\circ}C$, respectively. Enzymatic hydrolysis of four cellulosic substrates having varying crystallinity was evaluated. It was found that hydrolysis of amorphous region was followed by the hydrolysis of crystalline region. In order to examine the effect of adsorption of the enzyme onto the cellulosic substrates on the hydrolysis kinetics, adsorption studies were carried out. Time course of adsorption of low molecular weight endo-glucanase onto various cellulostances was observed for 25 min. The rate and amount of adsorption to amorphous cellulose was greater than those to the crystalline cellulose. This result suggested that the role of endo-glucanasc was more important to the hydrolysis of amorphous cellulose than to the crystalline region of the cellulose.

  • PDF

Numerical analysis of segmental tunnel linings - Use of the beam-spring and solid-interface methods

  • Rashiddel, Alireza;Hajihassani, Mohsen;Kharghani, Mehdi;Valizadeh, Hadi;Rahmannejad, Reza;Dias, Daniel
    • Geomechanics and Engineering
    • /
    • v.29 no.4
    • /
    • pp.471-486
    • /
    • 2022
  • The effect of segmental joints is one of main importance for the segmental lining design when tunnels are excavated by a mechanized process. In this paper, segmental tunnel linings are analyzed by two numerical methods, namely the Beam-Spring Method (BSM) and the Solid-Interface Method (SIM). For this purpose, the Tehran Subway Line 6 Tunnel is considered to be the reference case. Comprehensive 2D numerical simulations are performed considering the soil's calibrated plastic hardening model (PH). Also, an advanced 3D numerical model was used to obtain the stress relaxation value. The SIM numerical model is conducted to calculate the average rotational stiffness of the longitudinal joints considering the joints bending moment distribution and joints openings. Then, based on the BSM, a sensitivity analysis was performed to investigate the influence of the ground rigidity, depth to diameter ratios, slippage between the segment and ground, segment thickness, number of segments and pattern of joints. The findings indicate that when the longitudinal joints are flexible, the soil-segment interaction effect is significant. The joint rotational stiffness effect becomes remarkable with increasing the segment thickness, segment number, and tunnel depth. The pattern of longitudinal joints, in addition to the joint stiffness ratio and number of segments, also depends on the placement of longitudinal joints of the key segment in the tunnel crown (similar to patterns B and B').