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Studies on the Perception on Clinical Pharmaceutical Care and Clinical Pharmaceutical Sciences (임상약학, 임상약사, 임상약료와 임상약과학에 대한 인식도 조사 연구)

  • Chang, Min Jung;Cho, Eunae;Noh, Hayeon;Lee, Jangik I.
    • Korean Journal of Clinical Pharmacy
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    • v.24 no.3
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    • pp.169-182
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    • 2014
  • Background: There exist some different perceptions on clinical pharmacy between Korean and western societies. Since the pharmacists who received the 6-year pharmacy education join the pharmacy profession soon, it appears imperative to know whether the western-style clinical pharmacy is adaptable to Korean-style pharmacy education and profession. Methods: The authors surveyed 54 professors in the membership directory of the Korean College of Clinical Pharmacy (KCCP) on their perceptions on clinical pharmacy and clinical pharmacists, and their willingness for adapting clinical pharmaceutical care (CPC) and clinical pharmaceutical sciences (CPS) into clinical pharmacy education. The survey consists of 47 questions including dichotomized and Likert scale questionnaires in the areas of respondent demographics, clinical pharmacy, clinical pharmacists, CPC and CPS. Results: Of the 54 KCCP members surveyed, 29 completed the questionnaires in full and one in part. It appears that most KCCP members acknowledge the existence and importance of the two major fields of clinical pharmacy, CPC and CPS. Twenty-eight (96.6%) and seventeen members (68.0%) agreed to introduce CPC and CPS into the clinical pharmacy education in Korea, respectively. Seventeen (63.0%) answered CPC would be successfully adapted in Korea. Twenty (74.1%) agreed that it is desirable for clinical pharmacists to perform CPC and CPS simultaneously. Conclusion: Based on this survey, the authors suggest that pharmacy schools provide their students with the education opportunities on CPC to nurture clinical pharmacists through a master's program and CPS to foster clinical pharmaceutical scientists through a Ph.D. program.

Preparation of $SnO_2$ Semiconducting Gas Sensor by Wet Process (습식방법에 의한 $SnO_2$ 반도체 가스센사 제조)

  • 전병식;김홍대;최병현;최성근
    • Journal of the Korean Ceramic Society
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    • v.23 no.3
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    • pp.53-61
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    • 1986
  • A gas sensor which has been made by wet process had fabricated by coating each of the mixture on alumina tube and firing at 85$0^{\circ}C$ for 3hrs. A gas concentration such $H_2$, CO, $C_3H_8$, $C_2H_2$ and $CH_4$ vs its detection voltage characteristics has been in-vestigated on $SnO_2-In_2O_3-MgO$ system doped with PdO, $La_2O_3$, $ThO_2$, NiO and $Nb_2O_5$ The optimum sensitivity composition for various gases were 90w/o $SnO_2$-9w/o $In_2O_3$-1w/o MgO for $H_2$, $C_2H_2$ CO and $C_3H_8$ and 95w/o $SnO_2$-4w/o $In_2O_3$-1w/o MgO for $CH_4$. The sample which has been made by wet process than dry process had predominated sensitivity for each gases and particle size of the sample coprecipitated with PH=9 was 0.1${\mu}{\textrm}{m}$ The $SnO_2$-In2_O_3-MgO$ system doped with 2w/o $Nb_2O_5$ and NiO was the most sensitive for $H_2$ and $C_2H_2$ gas. In $SnO_2$-In2_O_3-MgO$ system doped with $ThO_2$ the sensitivity of $H_2$ gas was decreased but CO gas was in-creased when dopant con was increased.

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Impacts of Close-to-nature Management Technology on the Korean Pine Soil Chemical Properties in Northeast China

  • Wu, Yao;Qin, Kailun;Zhang, Jinfu;Li, Fengri
    • Journal of Forest and Environmental Science
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    • v.29 no.4
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    • pp.300-306
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    • 2013
  • Based on the guiding ideology of "Close-to-nature forestry", the soil chemical properties of Korean pine (Pinus koraiensis) plantation forest which was early done by canopy gap control were analyzed of Liangshui nature reserve in northeastern China. The results indicated that the nurture of forestry crevice diaphanous tended to improve the soil nutrient contents and significant differences of soil nutrients existed among different levels of soil for the same forest type of Korean pine. At 0< $H{\leq}20$ cm layer, the content of available nitrogen, available phosphorus, available potassium, total nitrogen and total phosphorus in artificial pure Korean pine forest are 640.28 $mg{\cdot}kg^{-1}$, 7.54 $mg{\cdot}kg^{-1}$, 275.91 $mg{\cdot}kg^{-1}$, 1.114% and 0.075%, they all higher than the other kinds of forests and for average 1.1 times, 1.4 times, 1.3 times, 1.6 times and 1.2 times. From the layer of $0<H{\leq}20$ cm to 20 cm < $H{\leq}40$ cm, soil nutrient indicators showed various degrees of decreasing in which organic matter had the greatest decline, decreasing by 170.64% while PH had the lowest decline, decreasing by 4.66%.

Development of the Environmentally Friendly Filling Material for the Underground Cavities using the Rock-dust and an Assessment on Filling and Material Characteristics (석분토를 이용한 지하공동의 친환경적 충전재 개발과 충전 및 재료특성 평가)

  • Ma Sang-Joon;Kim Dong-Min
    • Journal of the Korean Geotechnical Society
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    • v.21 no.9
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    • pp.35-44
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    • 2005
  • Recently, underground cavities such as limestone cavity and abandoned mine give rise to a lot of damage in SOC facilities. But there are many difficult problems such as delay of the working terms and enormous economic losses in finding a new method and changing construction design. In this study, a new filling material for underground cavities was developed using the stone-dust classified as industry waste polluting environment. As a result of test, filling material properties was that a compressive strength was $34{\~}60\;kgf/cm^2$, a change ratio in length was $0.268{\~}0.776\%$ and water absorption was $34.3{\~}46.9\%$. Also as a result of suspended mass test and pH test, it was confirmed that the developed filling material has a characteristic of non-separating in water and it was an environmentally friendly material.

Corona Discharge and Strong Electrolyzed Water Generation Characteristics of the Electrode System Bedded by Dielectric Pellets (유전체구 충진형 전극계의 코로나방전과 강전해수 발생특성)

  • 김진규
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.16 no.4
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    • pp.46-54
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    • 2002
  • A dielectric pellets bedded parallel plates with a membrane centered have been proposed as an ion separation and collection system in water. and effects of the relative dielectric constant and the applied square wave pulse voltage on the characteristics of ion separation and collection in tap water and NaCl dissolved tap water have been investigated. As a result, electrolyzed water of pH 3.1 and 10.6 were obtained with only tap water at the pulse current of 1.0[A] and flow rate of 0.5[LPM]. And the higher ionized water of pH 2.8 and pH 11.7 ware obtained in 0.1[%wt] NaCl dissolved water. When the dielectric pellets of BaTiO$_3$ having the highest dielectric constant were bedded in the ion separation and collection cell, the ionized water of pH 2.7 and pH 11.7 were obtained with only tap water. And the ionized water of pH 2.4 and pH 12.0 were obtained in 0.1[wt%] NaCl dissolved tap water with the dielectrics pellets bedded ones.

Multiple roles of phosphoinositide-specific phospholipase C isozymes

  • Suh, Pann-Ghill;Park, Jae-Il;Manzoli, Lucia;Cocco, Lucio;Peak, Joanna C.;Katan, Matilda;Fukami, Kiyoko;Kataoka, Tohru;Yun, Sang-Uk;Ryu, Sung-Ho
    • BMB Reports
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    • v.41 no.6
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    • pp.415-434
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    • 2008
  • Phosphoinositide-specific phospholipase C is an effector molecule in the signal transduction process. It generates two second messengers, inositol-1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. Currently, thirteen mammal PLC isozymes have been identified, and they are divided into six groups: PLC-$\beta$, -$\gamma$, -$\delta$, -$\varepsilon$, -$\zeta$ and -$\eta$. Sequence analysis studies demonstrated that each isozyme has more than one alternative splicing variant. PLC isozymes contain the X and Y domains that are responsible for catalytic activity. Several other domains including the PH domain, the C2 domain and EF hand motifs are involved in various biological functions of PLC isozymes as signaling proteins. The distribution of PLC isozymes is tissue and organ specific. Recent studies on isolated cells and knockout mice depleted of PLC isozymes have revealed their distinct phenotypes. Given the specificity in distribution and cellular localization, it is clear that each PLC isozyme bears a unique function in the modulation of physiological responses. In this review, we discuss the structural organization, enzymatic properties and molecular diversity of PLC splicing variants and study functional and physiological roles of each isozyme.

Microbiological and chemical changes in the Pacific oysters, Crassostrea gigas exposed to gamma radiation during ice storage (감마선 조사된 참굴의 빙장 기간중의 세균학 및 화학적 변화)

  • CHUNG Jong Rak
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.7 no.4
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    • pp.221-228
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    • 1974
  • 산란직전의 남해산 참굴(Crassostrea gigas)을 산채로 구입하여 통상조건하에서 탈각하여 얻은 굴육질을 polyethylene laminated aluminium pouch (Al+PE : 0.03+0.03mm) 속에 밀봉하여 살균선량(0.2Mrad) 및 멸균선량(2.0Mrad)의 감마선으조 조사하고, 한편, 100ppm의 염소수에 굴육질을 2분간 침지한 후 탈수하여 같은 방법으로 포장하여 35일간의 빙장기간중 세균학적 및 화학적 변화를 대조 굴(조사치 않고 염소수 처리하지 않은)의 경우와 비교하였다. 굴육질의 시초의 총균수는 g당 700-800에 달했고, 0.2 Mrad의 감마선 조사는 빙장 10일째의 저장 기간중의 총 균수를 검측할 수 있는 선 이하로 감소시켰으며 2.0 Mrad 조사는 20일째까지 거의 무균상태를 가져왔다. 감마선 조사는 또한 세균활동을 표시하는 대사물질인 TMA와 TCA soluble nitrogen의 축적을 현저히 억제시켰으며 빙장 후기부터 번식하기 시작하여 총균수가 g당 100,000을 초과케 된 35일째까지도 대조굴의 동일한 총균수 시기에 비하여 이 대사물의 축적억제가 현저했음은 감마선 조사의 효과가 총균수의 양적인 감소뿐만 아니라 동시에 TMA를 생산하고 단백질을 분해할 능력이 있는 세균제거 내지는 번식의 억제라는 선택적인 양면을 가지고 있음을 보여 준다. 염소수 처리한 굴육질의 경우 총균수의 양적인 감소효과는 현저하지 않했는데도 불구하고 감마선 조사 경우처럼 세균대사물질 축적의 철저한 억제를 가져 왔음은 주목할만 하다. 굴육질의 glycogen 함량은 사후 저장 기간 중 쉽사리 감소되지 않했으며 PH 측정으로 본 생굴의 신선도와의 관련성은 희박하며 조사와 염소수 처리굴의 경우 더욱 그러했다.

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Meta Analysis of the Correlation between early Childhood Teachers' Teaching Efficacy and their Job Satisfaction (유아교사의 교사효능감과 직무만족의 상관관계에 대한 메타분석)

  • Gong, Eun-Hwa
    • The Journal of the Korea Contents Association
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    • v.16 no.1
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    • pp.391-402
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    • 2016
  • The purpose of this study is to use meta-analysis as a research method to investigate the correlation between early child teachers' teaching efficacy and their job satisfaction, and thereby look into the effect size of the two variables and their sub-variables. To achieve the purpose, this researcher chose a total of 37 theses for analysis and collected 289 data for analyzing the effect size. Based on the data, CMA(Comprehensive Meta Analysis) 2.0 was applied. According to the analysis, the correlation between early childhood teachers' teaching efficacy and their job satisfaction was higher than the medium effect size on the basis of Cohen(1992) research. In the sub-variables of teaching efficacy, the correlation of personal teaching efficacy with job satisfaction showed higher effect size than that of general teaching efficacy. In the sub-variables of job satisfaction, the correlation between the belief in job and teaching efficacy showed the highest effect size. In terms of thesis type as a moderating variable, Ph.D dissertations showed higher effect size than journals or M.A. theses. As the result of the meta-analysis on publishing year and the number of samples, there was no statistical significance. On the basis of the analysis results, discussions and limitations of this study were suggested.

Therapeutic Effect of Teriparatide for Osteoporotic Thoracolumbar Burst Fracture in Elderly Female Patients

  • Yu, Dongwoo;Kim, Sungho;Jeon, Ikchan
    • Journal of Korean Neurosurgical Society
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    • v.63 no.6
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    • pp.794-805
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    • 2020
  • Objective : Teriparatide is known as an effective anabolic agent not only for severe osteoporosis but also for bone healing and union. We explored the possibility of teriparatide as an alternative treatment option for osteoporotic thoracolumbar (TL) burst fracture. Methods : This retrospective study enrolled 35 female patients with mean age of 73.77±6.71 years (61-88) diagnosed as osteoporotic TL burst fracture with ≥4 of thoracolumbar injury classification and severity (TLICS) score and no neurological deficits. All patients were treated by teriparatide only (12 of group A), teriparatide plus vertebroplasty (12 of group B), or surgical fixation with fusion (11 of group C), and followed up for 12 months. Radiological outcomes were evaluated using radiological parameters including kyphotic angle (KA), segmental vertebral kyphotic angle (SVKA), compression ratio (CR), and vertebral body height (anterior [AH], middle [MH], posterior [PH]). Functional outcomes were evaluated using visual analog scale (VAS) and Macnab classification (MC). Results : There were no statistical significant differences in age, bone mineral density (-3.36±0.73), and TLICS score (4.34±0.48) among the three groups (p>0.05). Teriparatide was administered during 8.63±2.32 months in group A and B. In 12-month radiological outcomes, there were significant restoration in SVKA, CR, AH, and MH of group B and KA, SVKA, CR, AH, and MH of group C compared to group A with no radiological changes (p<0.05). All groups showed similar significant improvements in 12-month functional outcomes, although group B and C showed a better 1-month VAS, 1-month MC, 3-month MC compared to group A (p<0.05). Conclusion : Non-surgical treatment with teriparatide showed similar 12-month functional outcomes compared to surgical fixation with fusion. The additional vertebroplasty to teriparatide and surgical fixation with fusion were more helpful to improve short-term functional outcomes with structural restoration compared to teriparatide only.

Studies on the Effect of Lactobacilli on Shelf life of Fresh Pork Chop (Lactobacilli가 신선돈육의 저장성에 미치는 효과)

  • Lee, Shin-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.1
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    • pp.51-55
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    • 1988
  • This studies conducted to investigates shelf-life of fresh pork chop by using various packaging method such as aerobic packaging, aerobic packaging with lactobacilli, vacuum packaging and vacuum packaging with lactobacilli. Bacteriological and physicochemical proper ties of fresh pork chop were also investigated during storage at $4^{\circ}C$. The effect of lactobacilli treatment showed significantly in aerobic packaging and vacuum pactaging. The growth of lactobacilli did not occur in lactobacilli inoculated fresh pork chops. The gram-negative bacteria which caused to meat spoilage was inhibited by lactobacilli. The PH of Pork showed increasing tendancy regardless of treatments, TBA and VBN value appeared to be relatively low during storage at $4^{\circ}C$. The maximum shelf life of each treatments was 12-15 days of aerobic packaging. 20-25 days of vacuum packaging and aerobic packaging with lactobacilli and 30-35 days of vacuum pactaging with lactobacilli at $4^{\circ}C$ respectively.

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