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Identification of Risky Subgroups with Sleep Problems Among Adult Cancer Survivors Using Decision-tree Analyses: Based on the Korean National Health and Nutrition Examination Survey from 2013 to 2016 (의사결정나무 분석을 이용한 성인 암경험자의 문제수면 위험군 예측: 2013-2016년도 국민건강영양조사 자료 분석)

  • Kim, Hee Sun;Jeong, Seok Hee;Park, Sook Kyoung
    • Journal of Korean Biological Nursing Science
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    • v.20 no.2
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    • pp.103-113
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    • 2018
  • Purpose: This study was performed to assess problems associated with sleep (short and long sleep duration) and to identify risky subgroups with sleep problems among adult cancer survivors. The study is based on the Korea National Health and Nutrition Examination Survey (KNHANES VI and VII) from 2013 to 2016. Methods: The sociodemographic and clinical data of 504 Korean cancer survivors aged 20-64 years was extracted from the KNHANES VI and VII database. Descriptive statistics for complex samples was used, and decision-tree analyses were performed using the SPSS WIN 24.0 program. Results: The mean age for survivors was approximately 51 years. The mean sleep duration was 6.97 hours; 36.2% of participants had short (< 7 hours) and 9.9% had long (> 8 hours) sleep duration. From the decision-trees analyses, the characteristics of the adult cancer survivors related to sleep problems were presented with six different pathways. Sleep problems were analyzed according to the survivors' sociodemographic information (age, education, living status, and occupation), clinical characteristics (body mass index, hypercholesterolemia, and anemia) and health-related quality of life (HRQoL). The HRQoL (${\leq}0.5$ or > 0.5 cutoff point) was a significant predictor of the participants' sleep problems because all six pathways were started from this predictor in the model. Conclusion: Health care professionals could use the decision-tree model for screening adult cancer survivors with sleep problems in clinical or community settings. Nursing interventions considering these specific individual characteristics and HRQoL level should be developed to have adequate sleep duration for Korean adult cancer survivors.

Effects of exercise on sleep EEG following caffeine administration (카페인 투여 후 운동이 수면에 미치는 효과)

  • 윤진환;이희혁
    • Journal of Life Science
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    • v.12 no.4
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    • pp.375-382
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    • 2002
  • The purpose of this experiment was to examine influence of acute exercise on nocturnal sleep which had been disrupted by caffeine(400mg$\times$3) thought the daytime. Six healthy young males aged 21.0$\times$0.2 yr with a history of low caffeine use. Subjects completed three conditions in a within-subject. At three conditions Sleep EEG were investigated: (1) nocturnal following quiet rest, (2) nocturnal sleep following the consumption of 1200mg of caffeine (3) nocturnal sleep following cycling at 60 min of 60% V $O_{2peak}$ with 1200mg of caffeine consumption. Sleep data were calculated for REM sleep, REM latency, sleep onset latency, sleep efficiency, sleep stages, SWS. Those data were analyzed using repeated-measures ANOVA of change scores. A main effect to, drug(caffeine) indicated that caffeine elicited sleep disturbance that is, TST and sleep onset latency increase and sleep efficiency and stage 4 decrease. The effects of exercise on sleep following caffeine intake generally improve sleep that is, stage 2, 3 and SWS increase and sleep onset latency decrease. A condition effect for sleep indicated sleep improvement after exercise Therefore The data supported a restorative theory of slow-wave sleep and suggest that acute exercise may be useful in promoting sleep and reducing sleep disturbance elevated by a high dose of caffeine.

Hydrolysate Preparation with High Content of 5-Hydroxytryptophan from Liquid Egg Protein and Its Sleep-Potentiating Activity

  • Kwon, Jung Il;Park, Yooheon;Han, Sung Hee;Suh, Hyung Joo
    • Food Science of Animal Resources
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    • v.37 no.5
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    • pp.646-653
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    • 2017
  • Alcalase hydrolysis of liquid egg white was used to produce 5-hydroxytryptophan (HTP) under various conditions and investigate the sleep-potentiating activity of liquid egg white hydrolysate (LEH) on pentobarbital-induced sleep. Alcalase hydrolysis yielded the highest content of 5-HTP ($13.50{\mu}g/mL$), while neutrase hydrolysis showed the lowest 5-HTP content ($5.23{\mu}g/mL$). The liquid egg white to water ratio (1:1) was optimal for the production of 5-HTP with high amino-nitrogen (A-N) content and degree of hydrolysis. The 5-HTP, amino-nitrogen, and degree of hydrolysis increased until 24 h of hydrolysis and slightly increased thereafter during hydrolysis with 2% and 5% enzyme addition. 5-HTP administration at doses of 6 and 9 mg/kg significantly increased sleep duration and decreased sleep latency time compared to that in the control (p<0.05). LEH (150 mg/mouse), which was equivalent to 5-HTP at 6 mg/kg, significantly decreased sleep latency time and increased sleep duration time compared to that in the control (p<0.05). Oral administration of LEH showed sleep-potentiating effects because of 5-HTP. The sleep-potentiating activity of LEH may have occurred through 5-HTP in our pentobarbital-induced sleep model. LEH may be a valuable alternative to sleep enhancement and may be used as a sleep-potentiating agent.

Classification of Sleep/Wakefulness using Nasal Pressure for Patients with Sleep-disordered Breathing (비강압력신호를 이용한 수면호흡장애 환자의 수면/각성 분류)

  • Park, Jong-Uk;Jeoung, Pil-Soo;Kang, Kyu-Min;Lee, Kyoung-Joung
    • Journal of Biomedical Engineering Research
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    • v.37 no.4
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    • pp.127-133
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    • 2016
  • This study proposes the feasibility for automatic classification of sleep/wakefulness using nasal pressure in patients with sleep-disordered breathing (SDB). First, SDB events were detected using the methods developed in our previous studies. In epochs for normal breathing, we extracted the features for classifying sleep/wakefulness based on time-domain, frequency-domain and non-linear analysis. And then, we conducted the independent two-sample t-test and calculated Mahalanobis distance (MD) between the two categories. As a results, $SD_{LEN}$ (MD = 0.84, p < 0.01), $P_{HF}$ (MD = 0.81, p < 0.01), $SD_{AMP}$ (MD = 0.76, p = 0.031) and $MEAN_{AMP}$ (MD = 0.75, p = 0.027) were selected as optimal feature. We classified sleep/wakefulness based on support vector machine (SVM). The classification results showed mean of sensitivity (Sen.), specificity (Spc.) and accuracy (Acc.) of 60.5%, 89.0% and 84.8% respectively. This method showed the possibilities to automatically classify sleep/wakefulness only using nasal pressure.

Redefining the Sleep-mode Operation For Wireless Low-power Communication (무선 저전력 통신을 위한 Sleep 모드의 세분화된 재정의)

  • Kim, Gu-Won;Park, Chang-Yun
    • Proceedings of the Korean Information Science Society Conference
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    • 2005.07a
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    • pp.409-411
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    • 2005
  • 이동 단말기 또는 센서 등이 사용하는 무선 통신에서는 통신에 소모되는 전력을 줄이는 문제가 중요시된다. 따라서 802.11 무선 LAN의 PSM과 같이, 대부분의 무선 통신 기술들은 일시적으로 NIC를 꺼서 전력소모를 줄이는 Sleep 모드 기능을 제공하고 있다. 그러나 Sleep 기간 동안 해당 단말로 보내져야할 트래픽이 다양한 형태로 발생할 수 있다는 점을 깊이 고려하지 않고 Sleep 모드의 동작을 정의하였으며, 그 결과 예상하지 못한 현상이 발생할 가능성이 상존한다. 본 연구에서는 이와 같은 현상의 예로서, 802.11의 PSM 노드에 발생할 수 있는 성능 반전과 에너지 소모를 통한 서비스 거부 공격을 제시한다. 또한 이와 같은 비정상적인 현상을 방지하는 방법으로서 기존의 Sleep을 폐쇄적(Closed) Sleep과 개방적(Open) Sleep으로 세분할 것을 제안한다.

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Factors Influencing Sleep of Elderly Women (재가 여성노인의 수면에 영향을 미치는 요인)

  • Sok, So-Hyune R.;Choi, Jin-Yi
    • Journal of Korean Academy of Nursing
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    • v.40 no.1
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    • pp.119-126
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    • 2010
  • Purpose: The study was done to identify factors influencing the sleep of elderly women. Methods: Data were collected by questionnaires from 203 elderly women in Seoul and Gyeong-gi province. Measures were physical health state, family support, life satisfaction, sleep, depression, and quality of life. Data were analyzed using Pearson correlation coefficients, t-test, ANOVA, and stepwise multiple regression with SPSS/WIN 13.0 version. Results: The mean score for sleep for elderly women was 39.04. Sleep for elderly women according to religion, education level, spouses, and monthly income showed significant differences. Sleep for elderly women showed significantly positive correlations to physical health state, family support, life satisfaction, and quality of life. The significant factors influencing sleep of elderly women were physical health state, family support, depression, and quality of life, which explained about 70.4% of the variance. The strongest factors influencing the sleep was physical health state. Conclusion: The results suggest that in developing nursing interventions and practice for sleep pattern of elderly women spouses and family support should be considered.

An update on the cause and treatment of sleep disturbance in children and adolescents with autism spectrum disorder

  • Seo, Wan Seok
    • Journal of Yeungnam Medical Science
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    • v.38 no.4
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    • pp.275-281
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    • 2021
  • Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by abnormalities in social communication/interaction and restrictive, repetitive patterns of behavior. ASD is a relatively common psychiatric disorder, with a prevalence of approximately 1.7% in children. Although many children and adolescents with ASD visit the hospital for medical help for emotional and behavioral problems such as mood instability and self-harming behavior, there are also many visits for sleep disturbances such as insomnia and sleep resistance. Sleep disturbances are likely to increase fatigue and daytime sleepiness, impaired concentration, negatively impact on daytime functioning, and pose challenges in controlling anger and aggressive behavior. Sleep disturbance in children and adolescents with ASD negatively affects the quality of life, nothing to say the quality of life of their families and school members. In this review, sleep disturbances that are common in children and adolescents with ASD and adolescents are presented. The developmental and behavioral impacts of sleep disturbances in ASD were also considered. Finally, non-pharmacological and pharmacological treatments for sleep disturbances in children and adolescents with ASD and adolescents are reviewed.

Nutrient Intake and Depression Based on Sleep Duration in Adult Women -Analysis of the Korea National Health and Nutrition Examination Survey, 2016 and 2018 Data- (성인 여성의 수면부족에 따른 영양소 섭취와 우울 -국민건강영양조사(2016년, 2018년)자료를 이용하여-)

  • Ji-Young, Shin;Mi-Eun, Yun;Sun-Hee, Kim;Geum-Seon, Lee
    • Journal of the Korean Dietetic Association
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    • v.29 no.1
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    • pp.31-48
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    • 2023
  • This study evaluated the nutrient adequacy ratio (NAR) and depression based on the sleep duration of adult women using data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2016 and 2018. A total of 4,507 subjects were divided into two groups: sleep hours<7 (lack of sleep, LS) and 7≤sleep hours (normal sleep, NS). For a more detailed analysis, the subjects were further divided into normal sleep with no depression (NSND) and lack of sleep with depression (LSWD) groups. When compared with NS group, the nutrient intake of the LS group was observed to be higher in carbohydrates (P<0.05) and thiamine (P<0.01), but had a significantly lower mean nutrient adequacy ratio (P<0.05). Also, the LS group showed a higher frequency of early menopause (P<0.001) and depression (P<0.05) than the NS group. In the analysis of anthropometry and blood parameters of the subjects based on their sleep duration, the LS group showed a lower body mass index (BMI, P<0.05), lower blood creatinine (P<0.01), glycated hemoglobin (P<0.05), and high-density lipoprotein (HDL) cholesterol (P<0.01) levels adjusted by age and menopause than the NS group. When compared to the NSND group, the LSWD group had a lower intake of cholesterol (P<0.05), vitamin A (P<0.05), vitamin C (P<0.05), and folic acid (P<0.05). There was no variation in the menopausal status, NAR, and mean nutrient adequacy ratio between the NSND and LSWD groups. However, there were differences in total blood cholesterol (P<0.05) and depression based on sleep duration. Apart from nutritional status, differences in BMI and blood parameters were observed based on sleep duration.

Sleep-Promoting Effect of Ecklonia cava: Ethanol Extract Promotes Non-rapid Eye Movement Sleep in C57BL/6N Mice

  • Yoon, Minseok;Kim, Jin Soo;Jo, Jinho;Han, Daeseok;Cho, Suengmok
    • Fisheries and Aquatic Sciences
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    • v.17 no.1
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    • pp.19-25
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    • 2014
  • We investigated the effects of Ecklonia cava ethanol extract (ECE) on sleep architecture and sleep profiles. ECE was orally administered at a dose of 100, 250, or 500 mg/kg to C57BL/6N mice and its effects were measured by recording electroencephalogram (EEG) and electromyogram. Administration of ECE (250 and 500 mg/kg) significantly induced non-rapid eye movement sleep (NREMS) without affecting rapid eye movement sleep. The increase in NREMS by ECE (500 mg/kg) was significant (P < 0.05) during the first 2 h after administration. In addition, ECE had no effect on EEG power density (an indicator of sleep quality) in NREMS. These results suggest that ECE induces NREMS in a manner similar to physiological sleep.

The Relationship of Late-Life Function and Disability(LLFDI) with Quality of Sleep in Older Men with Prostatic Hypertrophic Symptoms (노인의 전립샘 비대증상, 일상생활 수행능력 및 수면의 질)

  • Shin, Kyung-Rim;Gong, Su-Ja;Kang, Youn-Hee;Oak, Ji-Won;Lim, Eun-Ju
    • Korean Journal of Adult Nursing
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    • v.21 no.1
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    • pp.43-52
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    • 2009
  • Purpose: The purpose of this study was to investigate the relationships between LLFDI and quality of sleep in older men with prostatic hypertrophic symptoms. Methods: The secondary analysis of data collected for the 2nd stage BK(Brain Korea)21 project was performed. The original data were collected using a cross-sectional, face-to-face, and private interview method. The questionnaires consisted of prostatic hypertrophic symptoms, late-life function and disability, quality of sleep, and demographic profiles. Results: A total of 112 older men included in this study. The major findings of this study were as follow; 1) 29.5% of participants had more than moderate symptoms of prostatic hypertrophy. 2) There were a significant positive correlation of prostatic hypertrophic symptoms with subjective sleep quality, sleep latency, sleep disturbances, use of sleeping medication, and daytime dysfunction found, whereas there was a negative relationship with frequency dimension. 3) The LLFDI is significantly associated with urgency, weak stream, and intermittency. The quality of sleep is significantly associated with weak stream which explained 11.2% of variance. Conclusion: These results may contribute to a better understanding late-life function and disability, quality of sleep in older men with prostatic hypertrophic symptoms. Therefore, health programs for prompting older men's health should be planned based on results of the study.

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