• 축산식품과학과 산업
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• v.10 no.2
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• pp.42-52
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• 2021

• Korean journal of aerospace and environmental medicine
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• v.28 no.2
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• pp.19-22
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• 2018

Obstructive sleep apnea syndrome (OSAS) can lead to severe complications if left untreated, and therefore should be adequately diagnosed and treated, especially in airline workers. The aviation medical examiner (AME) should induce the patient to cooperate for the diagnosis and treatment of OSAS, by notifying the subject that it does not cause disqualification of the air service and that it is a disease that can be sufficiently controlled and treated by various treatment options. AME should also warn about medical complications and the possibility of serious air accident risks when untreated, and encourage the subject to receive appropriate diagnosis and steady treatment such as continuous positive airway pressure and/or surgical treatment.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.2
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• pp.191-197
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• 2019

Although auto-adjusting positive airway pressure (APAP) titration at home has several advantages over a CPAP titration in terms of convenience and time saving, there are still concerns as to whether it will show corresponding accuracy when compared to laboratory-based polysomnography (PSG) and CPAP titration. To obtain more evidence supporting home-based auto-titration, APAP titration was performed at home for patients who were presented with OSA on laboratory-based diagnostic PSG followed by CPAP titration. A total of 79 patients were included in the study. They all underwent split-night PSG with CPAP titration, and APAP titration for more than 7 days. The patients with successful titration at both situations were selected. The optimal pressure and apnea-hypopnea index (AHI) of CPAP and APAP titration were compared. The optimal pressure for CPAP and APAP titration were $7.0{\pm}1.8cmH_2O$ and $7.6{\pm}1.6cmH_2O$ (P<0.001), whereas the corresponding AHI were $1.3{\pm}1.5/h$ and $3.0{\pm}1.7/h$ (P<0.001). As a result, the achievement rates of optimal pressure for CPAP and APAP titration were 96.2% and 94.9% (r=-0.045, P=0.688), respectively. The results of this study did not differ with regard to the optimal pressure between CPAP and APAP titration. Overall, CPAP and APAP titrations should be chosen depending on a required situation.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.3
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• pp.255-261
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• 2016

The purpose of this study was to investigate the relationship between excessive daytime sleepiness (EDS) and blood pressure (BP) in patients with obstructive sleep apnea-hypopnea (OSAH). Patients were classified into four groups based on their severity of polysomnographic data: the snoring group (n=108)-characterized by Apnea-Hypopnea Index (AHI<5); the mild OSA group (n=186)-AHI $5{\leq}AHI$<15; the moderate OSA group (n=179)- AHI $15{\leq}AHI$<30; and the severe OSA group (n=233)-$AHI{\geq}30$. On the same night of polysomnography (PSG), BP levels were measured before sleeping (bedtime BP) and immediately after waking up on the following morning (morning BP). EDS was recognized as ESS (epworth sleepiness scale)${\geq}9$. The differences and correlations between BP and PSG parameters in the EDS and non-EDS groups of OSAH patients were analyzed. MAP was positively correlated with BMI, AHI, and total arousal (r=0.099, r=0.142, r=0.135, p<0.01, p<0.01, p<0.01), while negatively correlated with mean $SaO_2$ (r=-0.258, p<0.01). The EDS group had overall younger population ($47.2{\pm}11.3$ vs $50.3{\pm}11.4$, p=0.023), higher DBP (both bedtime and morning, $83.1{\pm}9.7$ vs $81.4{\pm}8.8$ and $86.4{\pm}9.2$ vs $83.6{\pm}9.7$)(p=0.031, p=0.047), and higher SBP (both bedtime and morning, $126.7{\pm}11.2$ vs $123.4{\pm}12.4$, $128.9{\pm}12.4$ vs $125.3{\pm}12.9$)(p=0.021, p=0.021) than compared with the non-EDS group. In hypertensive OSAH patients, patients with EDS were also younger and had higher total arousal number, as well as higher morning and bedtime DBP and SBP than compared with the non-EDS group (p<0.005, p=0.008, p<0.001 and p<0.001). EDS in OSAHS patients is a special phenotype characterized by younger age, higher DBP, more severe desaturation, and hypertension.

• Journal of Life Science
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• v.32 no.8
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• pp.601-610
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• 2022

P. tenebrifer (PT) belongs to the Diptera order and Stratiomyidae family. Recently, insect industry have been focused as food, animal feed and environmental advantages. γ-aminobutyric acid (GABA) and melatonin have been associated with regulating sleep and depression. GABA is the primary inhibitory neurotransmitter and is synthesized via biotransformation of monosodium glutamate (MSG) to GABA by lactic acid bacteria. In this study, we first used a GABA-enhanced PT extract, wherein GABA was enhanced by feeding MSG to PT. The underlying mechanisms preventing stress and insomnia were investigated in a corticosterone (CORT)-induced endoplasmic reticulum (ER) stress and chronic restraint stress (CRS)-exposed mouse model, as well as in pentobarbital (45 mg/kg)-induced sleep behaviors in mice. In the present study, the GABA peak was detected in high-performance liquid chromatography-evaporative light scattering detector (HPLC-ELSD) analysis and showed in Ptecticus tenebrifer water extract (PTW) but not in non-PTW extract. The results showed that PTW and Ptecticus tenebrifer with 70% ethanol extract (PTE) exerted neuroprotective effects by protecting against CORT-induced downregulation of phosphorylated extracellular signal-regulated kinase 1/2 (ERK1/2) and cAMP-response element binding protein (CREB) expression. In addition, PTW (300 mg/kg) significantly reduced CORT levels in CRS-exposed mice. Furthermore, PTW (100 and 300 mg/kg) significantly reduced sleep latency and increased total sleep duration in pentobarbital (45 mg/kg)-induced sleeping behaviors, which was related to serum melatonin levels. In conclusion, our results suggest that PTW exerts anti-stress and sleep-enhancing effects by regulating serum CORT and melatonin levels.

• Journal of Convergence for Information Technology
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• v.9 no.6
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• pp.130-139
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• 2019

This study investigates the future world of The Perfect Society (1967), science fiction written by Yunsung Moon that was a very rare science fiction publication in the 1960s. In The Perfect society, the main character Woo Sungoo, who was chosen to survive in a sleeping capsule as a representative of $20^{th}-century$ human beings, wakes in the $22^{nd}$ century where only women remain. He experiences this female utopia and finds that this world still contains as much abnormal antipathy to the others and absolute autocracy as the 20th-century world he remembers even though the future people succeed in overcoming the past problems like famine and pollution. The author warns that science alone without humanistic insight in a unity-oriented society cannot settle the human's fate; rather, it only changes the aspects of human conflict.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.52-52
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• 2023

저수지는 기존의 육상 수지에 직접적인 영향 뿐 만 아니라 수체가 육상에 머무르는 시간을 늘려 수온 및 수질에는 영향을 미친다. 이들이 환경 및 지역 기후 변화에 직접적인 영향을 미치는 주요인자로 기후 변화에 미치는 긍정적, 부정적 효과와 함께 중요성이 더 증대되고 있다. 위성 원격탐사는 북한 지역 등과 같은 현장 관측 자료의 수집이 어려운 지역을 포함한 전 지구 규모에서 저수량 변화를 추정하는데 유용한 자료를 제공한다. 우리는 광학 위성 (Landsat-8/9)과 능동형 마이크로파 위성 (Sentinel-1)를 활용해 한반도 지역에 분포하고 있는 저수지의 수체 면적을 산출하기 위해 2020년부터 2022년까지 자료를 수집했다. 저수지 표면적 산출은 전통적인 NDWI (Normalized Difference Water Index) 및 후방산란계수 (𝜎₀)에 multi-Otsu 방법을 적용하여 이진화 영상을 얻는 방식을 이용했다. 여전히 남아있는 과탐지 영역은 최대 표면적 영상과 상대 비교를 통해 제거했다. Landsat과 Sentinel-1 위성 원격 탐사 자료 기반 저수지 표면적은 높은 유사성이 있었고, 현장 및 위성 고도계 자료 기반 수면 고도 변화와 높은 관계성를 보여주었다. 실험을 통해 위성 원격탐사 자료를 활용한 한반도 지역 저수지의 저수량 변화을 추정했으며, 현장 관측자료와 비교했다. 이 추정 기술은 전 지구 저수지 및 호수로 확장할 수 있으며, 수문 모델의 검증자료 등으로 활용될 수 있다.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.496-496
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• 2022

차량 운행이 많은 고속도로, 주차장, 교량 등의 불투수 면적에서 발생하는 비점오염 물질은 차량에서 발생하는 배기가스와 연료, 부품 등이 비강우시 노면에 축적된 후 강우시 유출되는 특징을 가진다. 고속도로 휴게소의 경우 넓은 부지에 주차장이 위치하고, 대부분 불투수면으로 설계되었으며 차량이용대수에 따라 수질오염물질, 중금속 등이 축적되어 강우시 초기에 다량의 오염물질이 유출되는 특징을 가진다. 특히, 휴게소 노면 배출지점에서 강우시 약간의 탁수 유입과 함께 유기물, 영양염류의 농도가 다소 높았으며, 중금속은 주로 Pb, Cu, Zn의 농도가 높게 나타나는 것으로 연구 되었다. 본 연구는 고속도로 휴게소에서 발생하는 오염물질의 특성을 파악하기 위해 실시하였다. 휴게소 및 고속도로 인근에서 평시 발생하는 오염원의 차량 기인 여부를 판단하기 위해 비강우시 고속도로 노면 및 휴게소 오염원 배출 지점에서 토사 및 입자 샘플링을 실시하였으며, 이를 통해 입자에 흡착된 중금속 오염도 및 차량기인 여부를 판단하였다. 본 연구를 통해 고속도로 휴게소에서의 초기강우시 오염물질 처리방안 계획 수립시 기초자료로 활용할 수 있을 것으로 기대한다.

• Journal of The Korean Association For Science Education
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• v.24 no.6
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• pp.1118-1130
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• 2004

This article aims to (a) investigate children's images of a scientist's life style by comparing children's drawings about a scientist's schedule with those about a company employee's schedule in a weekday and on Sunday; and (b) examine the usefulness of 'Drawing A Scientist's Schedule (DASS)' test as a new instrument of learners' conceptions of a scientist and his/her work. To do those, thirty sixth- grade children participated in this study. The children, 15 boys and 15 girls, were selected from a classroom of an elementary school located in Gongju city. The children's drawings were analyzed in conjunction with individual interviews. The interviews facilitated the clarification of any ambiguous attributes of the drawings by questioning after their completion. Several significant conclusions can be drawn from this work: First, the children conceived that a scientist has more mandatory time, and less necessary and leisure time than does a company employee. Interestingly, many children thought that a scientist has similar life style on Sunday to that in a weekday, unlike a company employee. Second, in case of necessary time use in a weekday and on Sunday, the difference between a scientist and a company employee results from their sleeping time. Also, the children showed more various conceptions of a scientist's sleeping time than those of a company employee's sleeping time. Third, in case of mandatory time use, the children conceived that a scientist spends more time for his/her occupational work and less time for his/her housework activities than does a company employee. Fourth, the children's drawings showed that there is difference between a scientist's and a company employee's leisure time use and activities. Finally, the DASS test indicated its possibility and usefulness as an instrument for investigating learners' images on a scientist and his/her work. The instrument exhibited several distinctive children's conceptions that is difficult in identifying by using the DAST, a popular instrument.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.34 no.2
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• pp.70-79
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• 2021

Objectives : The purpose of this study is to report the effect of korean medical treatments on prurigo nodularis. Methods : We treated a 37-year-old female prurigo nodularis patient who has failed to respond to conventional therapies such as steroids and anti-histamines for 8 years. The patient was admitted to Daejeon University korean medical hospital for 21 days to get korean medical treatments including acupuncture, herbal-medicine, vapor treatment, venesection, pharmacopuncture and herbal-med aerosol therapy. The degree of improvement in prurigo nodularis was determined by the patient's subjective opinions on pruritus, febrile sensation, pain, and sleep disorders. Results : The results of this patient showed distinct improvements on pruritus, febrile sensation, pain, and sleep disorders. Pruritus decreased from 10 to 1, febrile sensation from 10 to 0, pain from 10 to 2, and sleeping hours increased 2 hours to 8 hours according to the patient's subjective opinions. Conclusions : This study shows the possibility that such korean medical treatments can improve prurigo nodularis.