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http://dx.doi.org/10.15324/kjcls.2019.51.2.191

Comparison for the Optimal Pressure between Manual CPAP and APAP Titration with Obstructive Sleep Apnea Patients  

Kim, Dae Jin (Department of Neurology, Pusan National University Yangsan Hospital)
Choi, Byoung Geol (Research Institute of Health Sciences, Graduate School, Korea University)
Cho, Jae Wook (Department of Neurology, Pusan National University Yangsan Hospital)
Mun, Sue Jean (Department of Otorhinolaryngology-Head & Neck Surgery, Pusan National University Yangsan Hospital)
Lee, Min Woo (Research Institute of Health Sciences, Graduate School, Korea University)
Kim, Hyun-Woo (Department of Neurology, Pusan National University Yangsan Hospital)
Publication Information
Korean Journal of Clinical Laboratory Science / v.51, no.2, 2019 , pp. 191-197 More about this Journal
Abstract
Although auto-adjusting positive airway pressure (APAP) titration at home has several advantages over a CPAP titration in terms of convenience and time saving, there are still concerns as to whether it will show corresponding accuracy when compared to laboratory-based polysomnography (PSG) and CPAP titration. To obtain more evidence supporting home-based auto-titration, APAP titration was performed at home for patients who were presented with OSA on laboratory-based diagnostic PSG followed by CPAP titration. A total of 79 patients were included in the study. They all underwent split-night PSG with CPAP titration, and APAP titration for more than 7 days. The patients with successful titration at both situations were selected. The optimal pressure and apnea-hypopnea index (AHI) of CPAP and APAP titration were compared. The optimal pressure for CPAP and APAP titration were $7.0{\pm}1.8cmH_2O$ and $7.6{\pm}1.6cmH_2O$ (P<0.001), whereas the corresponding AHI were $1.3{\pm}1.5/h$ and $3.0{\pm}1.7/h$ (P<0.001). As a result, the achievement rates of optimal pressure for CPAP and APAP titration were 96.2% and 94.9% (r=-0.045, P=0.688), respectively. The results of this study did not differ with regard to the optimal pressure between CPAP and APAP titration. Overall, CPAP and APAP titrations should be chosen depending on a required situation.
Keywords
Apnea-hypopnea index; Auto adjusting positive airway pressure; Continuous positive airway pressure; Hypopnea; Obstructive sleep apnea;
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