• Journal of Home Health Care Nursing
• /
• v.20 no.2
• /
• pp.141-151
• /
• 2013

Purpose: The purpose of this study was to examine the economic effectiveness of by conducting a literature review of published articles, masters theses, and doctoral dissertations. Method: Prior to the literature review, inclusion-exclusion criteria were established. We then reviewed 1,029 CINAHL, MEDLINE, and Cochrane DB papers, and 153 RISS papers collected between Results: A total of 12 studies met the inclusion-exclusion criteria.-effectiveness: 6 cost-effectiveness studies, 1 cost-utility studies, and 5 cost-benefit studies. Each of the 12 reviewed studies concluded that home care nursing had greater economic benefits than other compared healthcare services. Conclusion: Home care nursing has significant economic benefits in multi health care service settings and for various patient groups. Therefore these results will be used a critical evidence for the development of economically effective home based health care systems for future policy making.

• Health Policy and Management
• /
• v.10 no.4
• /
• pp.20-56
• /
• 2000

The purpose of this article was to evaluate the effects of reimbursement system on the basis of diagnosis-related groups(DRGs). We searched articles which was published from 1970 to 2000 using MEDLINE ； Key words "diagnosis-related groups, DRGs, prospective payment system, PPS. Then we reviewed 97 articles on classifying them into several categories of contents. It seems that the effects of DRGs in controlling hospitals cost in the U.S. was not clear cut. The U.S. Medicare PPS using DRGs remains vulnerable to compensatory increases in ambulatory care and long-term care facilities utilization despite cost per case and cost per admission being reduced. Also some research indicated the possibilities of deterioration in health care service quality. So putting theses results together, much more consideration is needed before the application of DRGs reimbursement system in Korea. Particularly there is the crucial difference between U.S. health care system and Korean, we must be aware of the limitations of DRGs and revise the DRG system to applicable in Korea.orea.

• Journal of Embryo Transfer
• /
• v.33 no.1
• /
• pp.49-54
• /
• 2018

Adenomyosis is a benign gynecological disease frequently affecting women of reproductive age. It has a negative impact on the quality of life, causing bleeding disorders, dysmenorrhea, chronic pelvic pain, and infertility. However, the molecular mechanisms involved in adenomyosis development remain unclear. This paper summarizes the reports found in the MEDLINE database on the molecular mechanisms involved in the development and progression of uterine adenomyosis. The literature search included the following terms: "adenomyosis," "adenomyoma," "pathogenesis," "molecular mechanisms," and "gynecological disorders." Only peer-reviewed, English-language journal articles were included. This review focuses on the molecular genetics, epigenetic modifications, and pivotal signaling pathways associated with adenomyosis development and progression, which will provide insights into and a better understanding of its underlying pathophysiology.

• The Journal of Advanced Prosthodontics
• /
• v.6 no.6
• /
• pp.547-554
• /
• 2014

Implant success is achieved by the synergistic combination of numerous biomechanical factors. This report examines the mechanical aspect of implants. In particular, it is focused on macrodesign such as thread shape, pitch, width and depth, and crestal module of implants. This study reviews the literature regarding the effect of implant thread geometry on primary stability and osseointegration under immediate loading. The search strategy included both in vitro and in vivo studies published in the MEDLINE database from January 2000 to June 2014. Various geometrical parameters are analyzed to evaluate their significance for optimal stress distribution, implant surface area, and bone remodeling responses during the process of osseointegration.

• Korean Parent-Child Health Journal
• /
• v.11 no.1
• /
• pp.15-24
• /
• 2008

Maternal depression is known to have important negative effects on mother, child and mother-child relationship. To review current research evidence of association between maternal depression and their children's health and development, relevant studies were identified using Medline and Kiss(Korean studies Information Service System). The majority of research has reported that children of mother with depression are at risk for impaired physical functioning, growth and developmental delays, and behavioral problems compared to general population. From these studies, it is suggested that these kinds of studies are necessary in this country to examine the relation between maternal depression and children's health and development. Recommendations are included for future research and screening programs for maternal depression.

• Genomics & Informatics
• /
• v.2 no.2
• /
• pp.99-106
• /
• 2004

In this paper we introduce PubMiner, an intelligent machine learning based text mining system for mining biological information from the literature. PubMiner employs natural language processing techniques and machine learning based data mining techniques for mining useful biological information such as protein­protein interaction from the massive literature. The system recognizes biological terms such as gene, protein, and enzymes and extracts their interactions described in the document through natural language processing. The extracted interactions are further analyzed with a set of features of each entity that were collected from the related public databases to infer more interactions from the original interactions. An inferred interaction from the interaction analysis and native interaction are provided to the user with the link of literature sources. The performance of entity and interaction extraction was tested with selected MEDLINE abstracts. The evaluation of inference proceeded using the protein interaction data of S. cerevisiae (bakers yeast) from MIPS and SGD.

• PNF and Movement
• /
• v.7 no.4
• /
• pp.1-7
• /
• 2009

Purpose : This paper reviews on the method of PNF stretching. Methods : This is literature study with Pubmed, medline, SPORT Discus, EBSCO, ProQuest and books. Results : PNF stretching is effective for increasing range of motion than static and ballistic stretching. CR(contract-relax) technique is effective and CRAC(contract-relax with agonist contraction) technique including agonist contraction is more effective. A minimum of one repetition, twice or three times per week is required for range of motion gains, needs to be conducted continueously. A minimum of 20% contraction intensity and more than 3 seconds contraction duration are needed to increase range of motion. Inclusion of static stretching of antagonist and agonist contraction is more effective. Conclusions : PNF stretching is more effective for increasing range of motion than other stretching methods, but, clinicians need to select proper techniques according to subjects and muscles, and conduct carefully when applying technique.

• Journal of Korean Medicine for Obesity Research
• /
• v.1 no.1
• /
• pp.63-75
• /
• 2001

Objectives : Many women associate one or more of their pregnancies with the development of adult obesity. This study was designed to determine influencing factors on postpartum weight retention and whether the breast-feeding was available to weight loss in puerperium. Methods : Articles from the literature on 'postpartum weight retention' were examined. Results : These articles show that different factors were related with postpartum weight retention. This study suggests that moderate weight gain during pregnancy is important to prevent postpartum maternal obesity. Especially weight gain from 20 weeks to 36 weeks of pregnancy is important. Falling in depression and anxiety during postpartum period should be avoided and social support is also needed. Delivery at the financially secure status is also recommended. Sufficient physical activity and exercise are needed to prevent from postpartum weight retention. Weight loss with dieting and exercise during lactation don't have a bad influence on the growth of infants.

• Journal of Pharmacopuncture
• /
• v.23 no.2
• /
• pp.62-70
• /
• 2020

Coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). Currently, the management of patients with COVID-19 depends mainly on repurposed drugs which include chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β and others. In this review, the potential of Nigella sativa (black cumin seeds) to treat the patients with COVID-19 analyzed, as it has shown to possess antiviral, antioxidant, anti-inflammatory, anticoagulant, immunomodulatory, bronchodilatory, antihistaminic, antitussive, antipyretic and analgesic activities. Medline/PubMed Central/PubMed, Google Scholar, Science Direct, Directory of open access journals (DOAJ) and reference lists were searched to identify articles associated with antiviral and other properties of N.sativa related to the signs and symptoms of COVID-19. Various randomized controlled trials, pilot studies, case reports and in vitro and in vivo studies confirmed that N.sativa has antiviral, antioxidant, anti-inflammatory, immunomodulatory, bronchodilatory, antihistaminic, antitussive activities related to causative oraganism and signs and symptoms of COVID-19. N. sativa could be used as an adjuvant therapy along with repurposed conventional drugs to manage the patients with COVID-19.

• Korean Journal of Clinical Pharmacy
• /
• v.20 no.1
• /
• pp.66-71
• /
• 2010

주의력결핍 과잉행동장애는 미국에서 약 200만 명의 어린이에게 나타나는 심각한 만성 신경행동학적 장애이다. 주의력결핍 과잉행동장애 치료의 중심은 약물요법이다. 그러나 현재 환자의 약 30%는 주의력결핍 과잉행동장애를 적응증으로 갖도록 허가된 의약품들을 사용해도 적절한 치료효과를 얻지 못하고 있는 상황이다. Modafinil은 methylphenidate나 amphetamines와 같은 각성제와는 다른 약리학적 기전으로 중추신경계를 항진시킨다. 본 연구는 modafinil의 주의력결핍 과잉행동장애 치료효과에 대한 최신 지견을 얻고자, 1990년부터 2010년 3월까지 MEDLINE에 등재된 논문을 ADHD와 Modafinil이라는 MeSH terms로 검색하여 추출한 자료 중에서 대조군이 사용된 무작위 배정 및 이중맹검 임상연구 사례만을 선별하여 임상적 유용성을 평가하였다. 현재 modafinil은 주의력결핍 과잉행동 장애 치료제로 허가된 의약품은 아니지만 최근 여러 국가에서 시행된 연구들은 modafinil이 안전하고 효과적인 주의력결핍 과잉행동장애 치료제일 수 있다는 결과를 보여주고 있다.