• 제목/요약/키워드: , 1608)

검색결과 171건 처리시간 0.038초

Feedback Linearization Control of the Looper System in Hot Strip Mills

  • Hwang, I-Cheol;Kim, Seong-Bae
    • Journal of Mechanical Science and Technology
    • /
    • 제17권11호
    • /
    • pp.1608-1615
    • /
    • 2003
  • This paper studies on the linearization of a looper system in hot strip mills, that plays an important role in regulating a strip tension or a strip width. Nonlinear dynamic equations of the looper system are analytically linearized by a static feedback linearization algorithm with a compensator. The proposed linear model of the looper is validated by a comparison with a linear model using Taylor's series. It is shown that the linear model by static feedback well describes nonlinearities of the looper system than one using Taylor's series. Furthermore, it is shown from the design of an ILQ controller that the linear model by static feedback is very useful in designing a linear controller of the looper system.

The Role of Complement in the Immunologic Microenvironment of Tumor Cells: Potential Therapeutic Targets

  • Jo, Kyeong Beom;Snape, Alison
    • 한국미생물·생명공학회지
    • /
    • 제44권4호
    • /
    • pp.420-431
    • /
    • 2016
  • The complement system comprises a set of essential molecules that bridge the innate and adaptive immune responses. Research has focused on how the complement system's destructive mechanism could potentially be harnessed for cancer treatment. However, cancer subverts the complement system to avoid immunosurveillance. In addition, a complement-triggered biological mechanism that contributes to cancer growth has been identified. Thus, drugs should be designed to homeostatically maintain a normal concentration of complement. This review explores three types of complement-related anti-cancer drugs: therapeutic antibodies, complement inhibitory drugs, and anti-complement regulatory drugs.

Production of Cellulases by Rhizopus stolonifer from Glucose-Containing Media Based on the Regulation of Transcriptional Regulator CRE

  • Zhang, Yingying;Tang, Bin;Du, Guocheng
    • Journal of Microbiology and Biotechnology
    • /
    • 제27권3호
    • /
    • pp.514-523
    • /
    • 2017
  • Carbon catabolite repression is a crucial regulation mechanism in microorganisms, but its characteristic in Rhizopus is still unclear. We extracted a carbon regulation gene, cre, that encoded a carbon catabolite repressor protein (CRE) from Rhizopus stolonifer TP-02, and studied the regulation of CRE by real-time qPCR. CRE responded to glucose in a certain range, where it could significantly regulate part of the cellulase genes (eg, bg, and cbh2) without cbh1. In the comparison of the response of cre and four cellulase genes to carboxymethylcellulose sodium and a simple carbon source (lactose), the effect of CRE was only related to the concentration of reducing sugars. By regulating the reducing sugars to range from 0.4% to 0.6%, a glucose-containing medium with lactose as the inducer could effectively induce cellulases without the repression of CRE. This regulation method could potentially reduce the cost of enzymes produced in industries and provide a possible solution to achieve the largescale synthesis of cellulases.

Antimicrobial Activity of Basil, Oregano, and Thyme Essential Oils

  • Sakkas, Hercules;Papadopoulou, Chrissanthy
    • Journal of Microbiology and Biotechnology
    • /
    • 제27권3호
    • /
    • pp.429-438
    • /
    • 2017
  • For centuries, plants have been used for a wide variety of purposes, from treating infectious diseases to food preservation and perfume production. Presently, the increasing resistance of microorganisms to currently used antimicrobials in combination with the appearance of emerging diseases requires the urgent development of new, more effective drugs. Plants, due to the large biological and structural diversity of their components, constitute a unique and renewable source for the discovery of new antibacterial, antifungal, and antiparasitic compounds. In the present paper, the history, composition, and antimicrobial activities of the basil, oregano, and thyme essential oils are reviewed.

수치모형실험을 이용한 여수로 설계 - 안동다목적댐 - (Spillway Design by Using Numerical Model Experiment - Case Study of AnDong Multipurpose Dam -)

  • 김대근;박선중;이영식;황종훈
    • 한국수자원학회:학술대회논문집
    • /
    • 한국수자원학회 2008년도 학술발표회 논문집
    • /
    • pp.1604-1608
    • /
    • 2008
  • 최근 기상이변 등에 따라 빈번히 발생하는 이상홍수에 대비하여 댐의 안정성 확보를 위한 댐설계기준이 강화되었고, 이에 따라 가능최대홍수량(PMF) 유입시 댐의 항구적인 안전성 확보를 위하여 치수능력 증대사업이 필요하게 되었다. 본 연구에서는 안동댐의 치수능력 증대사업의 일환으로 계획된 비상여수로에 대하여 2차원, 3차원 수치모형실험을 통해 비상여수로의 수리학적 안정성과 기능성을 검토하였다. 최적의 설계안을 결정하는데 필요한 자료를 제공하기 위하여 접근수로의 유황, 월류위어의 방류능력, 급경사수로 및 감세공의 유황을 검토하였다. 특히, 월류위어의 교각형상에 따른 수면형상, 조절부의 제원에 따른 방류량 검토, 조절부의 평면형상에 따른 유황, 급경사수로의 종단경사에 따른 유황, 저유량 방류시 플립버킷부에서의 사출궤적 등에 대한 검토 등을 수행하였다. 본 연구결과, 수치모형실험은 설계자에게 실용적인 해석도구로 사용될 수 있음을 보일 수 있었다.

  • PDF

Improve The Contrast Ratio on 20.1' S-IPS TFT-LCD with Ion-Beam-Alignment Technology

  • Chen, Yu-Hsien;Liu, Shen-Fa;Li, Huai-An;Huang, I-Chen;Sun, Oliver;Jaw, Jyh-Hong
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
    • /
    • pp.1605-1608
    • /
    • 2006
  • The contrast ratio, brightness, and uniformity of S-IPS panel, whose alignment process was employed by ion-beam-alignment (IBA) technology, were improved significantly compared with the convention rubbing's panel, because the light leakage has been reduced in dark state effectively. The IBA technology could generate a panel whose pretilt angle was stable and low after post-treatment process.

  • PDF

음향장이 열전달 과정에 미치는 영향 (The Effect of Acoustic Fields Formed in Heat Transfer Process)

  • 양호동;오율권
    • 대한기계학회:학술대회논문집
    • /
    • 대한기계학회 2003년도 춘계학술대회
    • /
    • pp.1603-1608
    • /
    • 2003
  • The Present Study reported on the experimental and numerical results of heat transfer in the acoustic fields induced by ultrasonic waves. The strong upwards flow called as acoustic streaming was visualized by a particle image velocimetry (P.I.V). in addition, the augmentation of heat transfer was experimentally investigated in the presence of acoustic streaming and was compared with the profiles of acoustic pressure calculated by the numerical analysis. Experimental and numerical studies clearly show that acoustic pressure variations are closely related to the augmentation of heat transfer.

  • PDF

핵 연료 교체 프로그램 구축을 위한 데이터 관리 프로세스 (Data management process for nuclear fuel replace program construction)

  • 김영진;신원식;정희철
    • 한국경영과학회:학술대회논문집
    • /
    • 대한산업공학회/한국경영과학회 2006년도 춘계공동학술대회 논문집
    • /
    • pp.1603-1608
    • /
    • 2006
  • Nuclear power plant have focused constituent that is always safety. However, period set to observe element that is economic performance keeping inner place now. Hereupon, in this study, chose fuel replace that is on one main activity doing at nuclear power plant for the target. And chose computerization and data management for fuel replace process to the direction.

  • PDF

전진경계법에서 Delaunay 탐색조건을 이용한 사면체 요소망의 자동 생성 (Automatic Tetrahedral Mesh Generation using Advancing Front Technique with Delaunay Node Searching)

  • 전성재;채수원
    • 한국정밀공학회:학술대회논문집
    • /
    • 한국정밀공학회 2003년도 춘계학술대회 논문집
    • /
    • pp.1605-1608
    • /
    • 2003
  • A unstructured tetrahedral mesh generation algorithm has been presented. To make better meshes in interior region using an advancing front technique, a connecting operator has been developed in addition to the existing operators. Before applying digging operators that generate new nodes inside of a meshing region, a connecting operator is employed that uses existing nodes which satisfy certain conditions for producing well-conditioned elements if possible. By introducing this new operator, tetrahedral meshing process becomes more robust and produces better quality of meshes.

  • PDF

하드디스크 드라이브 회전축계의 강제진동해석 (Forced Vibration Analysis of the Hard Disk Drive Spindle Systems)

  • 임승철
    • 한국소음진동공학회:학술대회논문집
    • /
    • 한국소음진동공학회 2000년도 춘계학술대회논문집
    • /
    • pp.1601-1608
    • /
    • 2000
  • This paper is concerned with the forced flexural vibration analysis of hard disk drive (HDD) spindle systems with multiple thin disks, supported by two ball bearings based on the finite element model. This is the extension of the previous work which analytically modeled every system component taking into account its structural flexibility and also the centrifugal stiffening effect especially for the disks. Among the end results, the forced time response is expectedly useful for the vibration control of the spindle itself or the position servo control of the magnetic head. On the other hand, the steady state responses such as the frequency response function and the unbalance response are useful for system identification. Futhermore, through a coordinate transformation the equations of motion is also derived with respect to the inertial frame for convenient analyses of certain classes.

  • PDF