• Bulletin of the Korean Chemical Society
• /
• v.24 no.8
• /
• pp.1193-1196
• /
• 2003

Palladium-catalyzed heteroannulation of 2-amino-3-iodoquinoline derivatives and 1-trimethylsilyl internal alkynes provided highly regioselective pyrrolo[2,3-b]quinolines with trimethylsilyl group next to the nitrogen atom in the pyrrole ring.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.11 no.6
• /
• pp.959-968
• /
• 2000

In this paper, a low phase noise frequency synthesizer used to TX local oscillator in BWLL RF tranceiver is presented. The phase-locked stable 25GHz-band frequencies in BWLL TX LO are obtained by using 2 GHz baseband frequency synthesizer, sixth-harmonic frequency multiplier and frequency doubler at 12 GHz band frequency input. The 25 GHz band frequency synthesizer presented in this paper has 3-output frequencies at 24.92 GHz, 25.10 GHz, 25.26 GHz. At 24.92 GHz frequency the synthesizer has 0.44 dBm output power and shows -87.93 dBc/Hz(a 10 KHz), -109.54 dBc/Hz (a100 KHz) phase noise characteristics .

• Journal of Life Science
• /
• v.16 no.4
• /
• pp.589-597
• /
• 2006

Genistein, a natural isoflavonoid phytoestrogen, is a strong inhibitor of protein tyrosine kinase and DNA topoisomerase activities. There are several studies documenting molecular alterations leading to cell cycle arrest and induction of apoptosis by genistein as a chemopreventive agent in a variety of cancer cell lines; however, its mechanism of action and its molecular targets on human bladder carcinoma and leukemic cells remain unclear. In the present study, we have addressed the mechanism of action by which genistein suppressed the proliferation of T24 bladder carcinoma and U937 leukemic cells. Genistein significantly inhibited the cell growth and induced morphological changes, and induced the G2/M arrest of the cell cycle in both T24 and U937 cells with a relatively stronger cytotoxicity in U937. The G2/M arrest in T24 cells was associated with the inhibition of cyclin A, cyclin B1 and Cdc25C protein expression without alteration of tumor suppressor p53 and cyclin-dependent kinase (Cdk) inhibitor p21(WAF1/CIP1). However, the inhibitory effects of genistein on the cell growth of U937 cells were connected with a marked inhibition of cyclin B1 and an induction of Cdk inhibitor p21 proteins by p53-independent manner. These data suggest that genistein may exert a strong anticancer effect and additional studies will be needed to evaluate the different mechanisms between T24 and U937 cells.

• Honam Mathematical Journal
• /
• v.31 no.3
• /
• pp.437-449
• /
• 2009

In this paper, we calculate the number of points on elliptic curves $E^{a^3}_0:y^2=x^3+a^3$ over ${\mathbb{F}}_p$ mod 24 and $E^b_0:y^2=x^3+b$ over ${\mathbb{F}}_p$ mod 6, where b is cubic non-residue in ${\mathbb{F}}^*_p$. For example, if p ${\equiv}$ 1 (mod 12) is a prime, and a and a(2t - 3) are quadratic residues modulo p with $3t^2{\equiv}1$ (mod p), then the number of points in $E^{a^3}_0:y^2=x^3+a^3$ is congruent to 0 modulo 24.

• Proceedings of the Korean Institute of Surface Engineering Conference
• /
• 2017.05a
• /
• pp.119.1-119.1
• /
• 2017

Fe-(10, 24 wt.%) Gd-B 합금을 진공 주조하고 상분석과 내식성 평가 및 표면 경도를 측정하였다. 주조된 Fe-10 wt.% Gd-B 합금의 상은 주로 $Fe_2Gd$, $Fe_3Gd$, $B_4FeGd$, $GdB_2$이었으며, Fe-24 wt.% Gd-B 합금은 주로 $Fe_2Gd$, $Fe_3Gd$, $Fe_9Gd$, $Fe_{17}Gd_2$, $B_4FeGd$, $GdB_2$이었다. 인공해수 분위기에서의 부식 속도와 부식 전위는 각각 2.771, 2.914 [$mA/cm^2$]과 -623.9, -607.8 [$mV_{SHE}$]이었다. 표면 경도는 각각 220, 208 [Hv] 이었다. Gd 함량이 증가할수록 부식 속도는 증가하였고 표면 경도는 감소하는 경향을 보였다.

• Progress in Superconductivity and Cryogenics
• /
• v.24 no.4
• /
• pp.55-58
• /
• 2022

Carbon-based doping to MgB₂ superconductor is the simplest approach to enhance the critical current densities under magnetic fields. Carbon quantum dots is synthesized in this work as a carbon provider to MgB₂ superconductors. Polyvinyl Pyrrolidone is pyrolyzed and dispersed in dimethylfomamide solvent as a dopant to the mixture of Mg and B powders. Doped MgB₂ bulk samples clearly show the decrease of a-axis lattice constant, grain refinements, and broadening of FWHM of diffraction peaks compared to un-doped MgB₂ possibly due to the carbon substitution and/or boron vacancy at the boron site in MgB₂ lattice. Also, high-field J_c for the doped MgB₂ is enhanced significantly with the crossover about 3 T at 5 & 20 K when increasing the doping of carbon quantum dots.

• Natural Product Sciences
• /
• v.2 no.1
• /
• pp.9-13
• /
• 1996

Three new withanolides, designated as withatatulins B, C, and D, were isolated from the fresh flowers of Datura tatula Linn. Detailed spectral analysis of these compounds permitted advancement of their structures respectively, as $5{\beta},6{\beta}-epoxy-12{\beta}$,21-dihydroxy-1-oxo-witha-2,24-dienolide (2), $6{\beta},12{\beta},21-trihydroxy-1-oxowitha$ 2, 4,24-trienolide (3) and $5{\beta},6{\beta},12{\beta}$,21-tetrahydroxy-1-oxo-witha-2,24-dienolide (4a). Withanolides with oxygen functions both at 12 and 21-positions are rare and first reported from Datura species.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.29 no.10
• /
• pp.758-765
• /
• 2018

This paper presents a 24-GHz frequency-modulated continuous wave(FMCW) radar transceiver with two Rx and one Tx channels in 65-nm complementary metal-oxide-semiconductor(CMOS) process and implemented it on a radar system using the developed transceiver chip. The transceiver chip includes a $14{\times}$ frequency multiplier, low-noise amplifier, down-conversion mixer, and power amplifier(PA). The transmitter achieves >10 dBm output power from 23.8 to 24.36 GHz and the phase noise is -97.3 GHz/Hz at a 1-MHz offset. The receiver achieves 25.2 dB conversion gain and output $P_{1dB}$ of -31.7 dBm. The transceiver consumes 295 mW of power and occupies an area of $1.63{\times}1.6mm^2$. The radar system is fabricated on a low-loss Duroid printed circuit board(PCB) stacked on the low-cost FR4 PCBs. The chip and antenna are placed on the Duroid PCB with interconnects and bias, gain blocks and FMCW signal-generating circuitry are mounted on the FR4 PCB. The transmit antenna is a $4{\times}4$ patch array with 14.76 dBi gain and receiving antennas are two $4{\times}2$ patch antennas with a gain of 11.77 dBi. The operation of the radar is evaluated and confirmed by detecting the range and azimuthal angle of the corner reflectors.

• Asian-Australasian Journal of Animal Sciences
• /
• v.31 no.2
• /
• pp.237-244
• /
• 2018

Objective: Piglet pre-weaning mortality is an important variable indicating the efficacy of farrowing management and animal well-being during lactation. The present study determined the association of newborn traits measured soon after birth with piglet pre-weaning mortality and growth. Methods: In total, 805 piglets born from 57 multiparous sows were investigated. Their blood oxygen saturation, blood glucose and rectal temperature at 24 h after birth (RT24h) were monitored. Birth order, sex, skin color, integrity of the umbilical cord, attempts to stand and birth intervention were monitored. Piglets were weighed at day 0, 7, and 21 to evaluate average daily gain (ADG). Results: Piglet pre-weaning mortality for lactation period was 12.6% and cumulative mortality during the first 7 days of age was 8.6%. A higher proportion of piglets with pale skin color died compared to piglets with normal skin color (26.7% vs 7.7%, p<0.001). A higher (p<0.001) proportion of piglets that attempted to stand after 5 min (38.5%) died compared to piglets that attempted to stand within 1 min (6.3%) after birth. Piglet body weight at birth ($BW_B$), blood glucose and the number of piglets born alive (BA) were correlated with ADG (p<0.05). Piglets with $BW_B$ <1.30 kg had higher (p<0.001) mortality rate than piglets with $BW_B{\geq}1.80 kg$ (19.0% vs 3.3%) and piglets with $BW_B$ 1.30 to 1.79 kg (4.0%). Piglet with RT24h <$37.0^{\circ}C$ had higher (p<0.001) mortality rate (86.2%) than piglets with RT24h >$38.5^{\circ}C$ (3.9%). Conclusion: Low $BW_B$ and low RT24h compromise piglet survival during the lactation period in the tropical conditions. Piglets in the litters with a high BA, low $BW_B$ and low blood glucose have reduced ADG.

• Pediatric Infection and Vaccine
• /
• v.27 no.2
• /
• pp.111-116
• /
• 2020

Purpose: Human parvovirus B19 infection is widespread and has a heterogeneous clinical spectrum, ranging from asymptomatic infection to potentially life-threatening complications. We investigated the various clinical features of human parvovirus B19 infection during an outbreak of the virus in our community. Methods: A retrospective chart review study was conducted at the Pusan National University Children's Hospital from December 2017 to April 2019. We investigated the clinical features of children with parvovirus B19 immunoglobulin M or parvovirus B19 DNA detected using polymerase chain reaction. Results: A total of 24 children were diagnosed with parvovirus B19 infection. Twelve (50%) had lace form rashes, and four (16.7%) had petechial rashes. Two (8.3%) were diagnosed with fever without a focus. Six (25%) developed aplastic crisis as a complication of infection, of whom three were previously diagnosed with hereditary spherocytosis and three with acute lymphoblastic leukemia. Conclusions: In addition to erythema infectiosum, the parvovirus B19 infection can present clinically with various types of rashes and fever without a focus. Furthermore, hematologic manifestations such as neutropenia and aplastic crisis can occur during infection.