• Title/Summary/Keyword: $T_1$ and $T_2$ relaxation

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Correction of Receiver Gain using Noise′s Standard Deviation for Reconstruction of T$_1$/T$_2$ Maps (T$_1$/T$_2$ maps 의 재구성을 위해 잡음의 표준편차를 이용한 수신 증폭률 보정)

  • 김미나;김성은;신승애;정은기
    • Progress in Medical Physics
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    • v.10 no.3
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    • pp.125-131
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    • 1999
  • T$_1$/T$_2$ weighted images are being used to give the characteristic contrast among the various tissues and the norma;/abnormal tissues. Abnormalities in tissues, in general, accompany the biochemical changes and eventually structural ones in which results in the change in T$_1$ and T$_2$ relaxation times of water protons. It has been suggested that the mapping of T$_1$/T$_2$ values may serve as a possible tool for the quantitative evaluation of the degree of abnormality. On reconstructing T$_1$/T$_2$ maps(or any other MR parametric map), only corresponding variables are to be varied, such as TE for T$_2$, TI or TR for T$_1$ and b-factor for diffusion images. But often the receiver gain is taken for the optimal usage of A/D converter, so that the set of the image data has different receiver gain. It must be corrected before any attempt to reconstruct the maps. Here we developed method of correcting receiver gain variation effect, using the standard deviation of noise on individual image. The resultant T$_1$ and T$_2$ values were very comparable to the other reported values.

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STABILIZATION FOR THE VISCOELASTIC KIRCHHOFF TYPE EQUATION WITH A NONLINEAR SOURCE

  • Kim, Daewook
    • East Asian mathematical journal
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    • v.32 no.1
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    • pp.117-128
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    • 2016
  • In this paper, we study the viscoelastic Kirchhoff type equation with a nonlinear source $$u^{{\prime}{\prime}}-M(x,t,{\parallel}{\bigtriangledown}u(t){\parallel}^2){\bigtriangleup}u+{\int}_0^th(t-{\tau})div[a(x){\bigtriangledown}u({\tau})]d{\tau}+{\mid}u{\mid}^{\gamma}u=0$$. Under the smallness condition with respect to Kirchhoff coefficient and the relaxation function and other assumptions, we prove the uniform decay rate of the Kirchhoff type energy.

Pulsed field magnetization of multi-turn short-circuited stabilized double pancake HTS coil

  • Korotkov, V.S.;Krasnoperov, E.P.;Brazhnik, P.A.;Kartamyshev, A.A.;Bishaev, A.M.;Kozinsteva, M.V.
    • Progress in Superconductivity and Cryogenics
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    • v.21 no.1
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    • pp.1-5
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    • 2019
  • The pulsed field magnetization of the short-circuited soldered double pancake coil made of stabilized commercial high-Tc superconductor (HTS) tape is experimentally studied. The evolution of the shielding current induced by the pulsed field and the trapped field after the pulsed magnetization was measured at 77 K. It is shown that the trapped field in the coil is close to the value reached in the field cooling process and reduces weakly at 5-fold increasing of pulsed field amplitude. The current relaxation at t~2 ms after the pulse is defined by the current sharing between the tape's copper coating and the $YBa_2Cu_3O_{7-d}$ layer. In the intermediate time scale (1 s < t < 100 s) the flux creep in HTS layer dominates. At t > 100 s the current's relaxation is defined by the resistance of soldered joint between tapes.

Effect of Curcuma Longa Derived-curcumin on Vascular Tension (강황 유래 Curcumin의 Rho-kinase 억제를 통한 혈관이완작용)

  • Je, Hyun Dong
    • YAKHAK HOEJI
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    • v.57 no.5
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    • pp.376-381
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    • 2013
  • The present study was undertaken to investigate the influence of curcumin on vascular smooth muscle contractility and to determine the mechanism involved. We hypothesized that curcumin, the primary ingredient of Curcuma longa, plays a role in vascular relaxation through inhibition of Rho-kinase in rat aortae. Denuded arterial rings from male Sprague-Dawley rats were used and isometric tensions were recorded using a computerized data acquisition system. Interestingly, curcumin inhibited fluoride-induced contraction but didn't inhibit phorbol ester-induced contraction suggesting that additional pathways different from endothelial nitric oxide synthesis might be involved in the vasorelaxation. Furthermore, curcumin significantly inhibited fluoride-induced increases in pMYPT1 levels. On the other hand, it didn't significantly inhibit phorbol ester-induced increases in pERK1/2 levels suggesting the mechanism involving inhibition of fluoride-induced MYPT1 phosphorylation. This study provides evidence that curcumin induces vascular relaxation through inhibition of Rho-kinase in rat aortae.

A study on the structural changes and the TSC characteristics of epoxy composites cured with acid-anhydride (산무수물 경화된 에폭시 복합체의 구조변화와 TSC특성에 관한 연구)

  • 왕종배;이준웅
    • Electrical & Electronic Materials
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    • v.7 no.1
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    • pp.32-41
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    • 1994
  • In this study, the TSC spectroscopy has been applied to investigate the influence of structural change due to a process of curing reaction on the electrical properties of epoxy composites cured with acid-anhydride. Five TSC peaks appeared in -160-250[.deg.C]: in the low temperature region below glass transition temperature(T$\_$g/), three relaxation mode peaks due to action of side chains, substitution group or terminal groups have been observed, a peak associated with T$\_$g/, appeared in 110[.deg. C] and p peak due to ionic space charges located in 150[.deg.C]. Each peak was separated into elementary peaks by the partial polarization procedure, and the distribution of activation energy and relaxation time were analized to clearify the origin of each peak. Also, overaboundantly added hardener separated a .betha. peak near 10[.deg. C] into two peaks of .betha.$\_$1/(10.deg. C) and .betha.$\_$2/(20.deg. C) according to increasement of forming field, and the separated hardener was oxidated thermally with increasing surrounding temperatures. The expansion of the free volume need in molecular motion and the reduction of the structural packing density through thermal oxidation process increased TSC between .alpha. peak and .betha. peak and decreased T$\_$g/.

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Detection of Iron Nanoparticles using Nuclear Magnetic Resonance Relaxometry and Inverse Laplace Transform

  • Kim, Seong Min
    • Journal of Biosystems Engineering
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    • v.39 no.4
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    • pp.345-351
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    • 2014
  • Purpose: Rapid detection of bacteria is very important in agricultural and food industries to prevent many foodborne illnesses. The objective of this study was to develop a portable nuclear magnetic resonance (NMR)-based system to detect foodborne pathogens (E. coli). This study was focused on developing a method to detect low concentrations of magnetic nanoparticles using NMR techniques. Methods: NMR relaxometry was performed to examine the NMR properties of iron nanoparticle mixtures with different concentrations by using a 1 T permanent magnet magnetic resonance imaging system. Exponential curve fitting (ECF) and inverse Laplace transform (ILT) methods were used to estimate the NMR relaxation time constants, $T_1$ and $T_2$, of guar gum solutions with different iron nanoparticle concentrations (0, $10^{-3}$, $10^{-4}$, $10^{-5}$, $10^{-6}$, and $10^{-7}M$). Results: The ECF and ILT methods did not show much difference in these values. Analysis of the NMR relaxation data showed that the ILT method is comparable to the classical ECF method and is more sensitive to the presence of iron nanoparticles. This study also showed that the spin-spin relaxation time constants acquired by a Carr-Purcell-Meiboom-Gill (CPMG) pulse sequence are more useful for determining the concentration of iron nanoparticle solutions comparwith the spin-lattice relaxation time constants acquired by an inversion recovery pulse sequence. Conclusions: We conclude that NMR relaxometry that utilizes CPMG pulse sequence and ILT analysis is more suitable for detecting foodborne pathogens bound to magnetic nanoparticles in agricultural and food products than using inversion recovery pulse sequence and ECF analysis.

T2 Relaxographic Mapping using 8-echo CPMG MRI Pulse Sequence

  • E-K. Jeong;Lee, S-H.;J-S. Suh;Y-Y wak;S-A. Shin;Y-K. Kwon;Y. Huh
    • Journal of the Korean Magnetic Resonance Society
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    • v.1 no.1
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    • pp.7-20
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    • 1997
  • The mapping of the spin-spin relaxation time T2 in pixed-by-pixel was suggested as a quantitative diagnostic tool in medicine. Although the CPMG pulse sequence has been known to be the best pulse sequence for T2 measurement in physics NMR, the supplied pulse sequence by the manufacture of MRI system was able to obtain the maximum of 4 CPMG images. Eight or more images with different echo time TEs are required to construct a reliable T2 map, so that two or more acquisitions were required, which easily took more than 10 minutes. 4-echo CPMG imaging pulse sequence was modified to generate the maximum of 8 MR images with evenly spaced echo time TEs. In human MR imaging, since patients tend to move at least several pixels between the different acquisitions, 8-echo CPMG imaging sequence reduces the acquisition time and may remove any misregistration of each pixel's signal for the fitting T2. The resultant T2 maps using the theoretically simulated images and using the MR images of the human brain suggested that 8 echo CPMG sequence with short echo spacing such as 17∼20 msec can give the reliable T2 map.

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Pulsed NMR Study of $CuF_{2}.2H_{2}O$ ($CuF_{2}.2H_{2}O$의 펄스 핵자기공명 연구)

  • Lee, C.E.;Yoon, E.H.;Lee, C.H.;Kim, K.;Jeon, S.J.
    • Journal of the Korean Magnetics Society
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    • v.3 no.1
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    • pp.13-17
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    • 1993
  • We have studied $CuF_{2}.2H_{2}O$ using $^{1}H$ and $^{19}F$ pulsed nuclear magnetic resonance at 30 MHz. From the data of lineshapes, the spin-lattice relaxation times ($T_1$) and the spin echo decay times, lattice dynamics in the structure is investigated. $T_1$ data from both $^{1}H$ and $^{19}F$ NMR indicate that spin-lattice relaxation is dominated by the paramagnetic ion centers at the Cu sites. The lineshapes at room temperature appear to be strongly affected by exchange narrowing and motional narrowing.

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Effects of Siegesbeckia Glabrescens on the Vascular Relaxation and Antioxidative Status (희렴의 혈관이완 효능과 항산화 동태에 관한 연구)

  • 신흥묵
    • The Journal of Korean Medicine
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    • v.21 no.1
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    • pp.77-83
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    • 2000
  • This study investigated the effects of Siegesbeckia glabrescens, an antihypertensive remedy, on the contraction evoked by phenylephrine and KCl in isolated rat thoracic arata, and also analyzed antioxidative status in vitro. Siegesbeckia glabrescens revealed dose-dependent relaxation on phenylephrine(PE)/KCl-induced arterial contraction and more markedly on PE-induced contraction. Siegesbeckia glabrescens reduced malondialdehyde(MDA)levels, Phosphatidyl choline-liposome(PC-OOH) contents, linoleic acid-induced lipid peroxidation and exerted 1,1-diphenyl-2- picryl-hydrazyl(DPPH) radical scavenging effect, in vitro. These results indicated that Siegesbeckia glabrescens doesn't relaxe artery through a blocking α-adrenergic receptor and calcium channel mediated by voltage-operated calcium channel, and it s antioxidative effects may be involved in endothelium-dependent relaxation of arteries via vascular protective properites. (J Korean Oriental Med 2000;21(1):77-83)

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Molecular Dynamics in Paraelectric Phase of KH2PO4 Crystals Studied by Single Crystal NMR and MAS NMR

  • Paik, Younkee;Chang, Celesta L.
    • Journal of the Korean Magnetic Resonance Society
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    • v.17 no.1
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    • pp.19-23
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    • 2013
  • The temperature dependences of the NMR spectrum and the spin-lattice relaxation times in $KH_2PO_4$ were investigated via single-crystal NMR and MAS NMR. The stretched-exponential relaxation that occurred because of the distribution of correlation times was indicative of the degree of the distribution of the double-well potential on the hydrogen bond. The behaviors responsible for the strong temperature dependences of the $^1H$ and $^{31}P$ spin-lattice relaxation times in the rotating frame $T_{1{\rho}}$ in $KH_2PO_4$ are likely related to the reorientational motion of the hydrogen-bond geometry and the $PO_4$ tetrahedral distortion.