• Title/Summary/Keyword: $T2^*$ weighted

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Diffusion-Weighted MR Neurography with Unidirectional Motion-Probing Gradient to Evaluate Lumbar Nerve Roots at 1.5T MR (요추 신경근 평가를 위한 1.5T MR의 단일 방향 경사자장을 사용한 확산강조 자기공명신경조영)

  • Na Yeon Yoon;Doo Hoe Ha;Sang Min Lee;Hye Jung Choi
    • Journal of the Korean Society of Radiology
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    • v.85 no.3
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    • pp.607-617
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    • 2024
  • Purpose Recent studies have demonstrated the usefulness of diffusion-weighted MR neurography (DW MRN) for assessing nerve roots. This study aimed to evaluate the utility of DW MRN with a unidirectional motion-probing gradient (MPG) for the lumbar nerve roots at 1.5T MR. Materials and Methods Sixty-four lumbar spine MRI scans with DW MRN using anteroposterior unidirectional MPG were retrospectively analyzed. Any changes in the 512 lumbar spinal nerve roots from L3 to S1 were evaluated using T2-weighted imaging (T2WI), contrast-enhanced T1-weighted imaging (CE T1WI), and DW MRN, with agreement and correlation analysis. Results T2WI revealed compression of 78 nerve roots, and CE T1WI revealed 52 instances of nerve root enhancement. Sixty-seven nerve roots showed swelling and hyperintensity on DW MRN. A total of 42 nerve roots showed changes in the CE T1WI and DW MRN sequences. Moderate to substantial agreement and moderate positive correlation were observed between DW MRN and CE T1WI, as well as DW MRN and T2WI (κ = 0.59-0.65, ρ = 0.600-0.653). Conclusion DW MRN with unidirectional anteroposterior MPG can help evaluate neuritisrelated changes in spinal nerve roots and could serve as a sequence capable of complementing or substituting gadolinium CE imaging.

Weighted Fuzzy Reasoning Using Weighted Fuzzy Pr/T Nets (가중 퍼지 Pr/T 네트를 이용한 가중 퍼지 추론)

  • Cho, Sang-Yeop
    • The KIPS Transactions:PartB
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    • v.10B no.7
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    • pp.757-768
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    • 2003
  • This paper proposes a weighted fuzzy reasoning algorithm for rule-based systems based on weighted fuzzy Pr/T nets, where the certainty factors of the fuzzy production rules, the truth values of the predicates appearing in the rules and the weights representing the importance of the predicates are represented by the fuzzy numbers. The proposed algorithm is more flexible and much closer to human intuition and reasoning than other methods : $\circled1$ calculate the certainty factors using by the simple min and max operations based on the only certainty factors of the fuzzy production rules without the weights of the predicates[10] : $\circled2$ evaluate the belief of the fuzzy production rules using by the belief evaluation functions according to fuzzy concepts in the fuzzy rules without the weights of the predicates[12], because this algorithm uses the weights representing the importance of the predicates in the fuzzy production rules.

Development of the Line Scan Diffusion Weighted Imaging at Low Tesla Magnetic Resonance Imaging System (저자장 자기공명영상시스템에서 선주사확산강조영상기법 개발)

  • Hong, Cheol-Pyo;Lee, Dong-Hoon;Lee, Do-Wan;Lee, Man-Woo;Paek, Mun-Young;Han, Bong-Soo
    • Journal of the Korean Society of Radiology
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    • v.2 no.2
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    • pp.31-38
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    • 2008
  • Line scan diffusion weighted imaging (LSDI) pulse sequence for 0.32 T magnetic resonance imaging (MRI) system was developed. In the LSDI pulse sequence, the imaging volume is formed by the intersection of the two perpendicular planes selected by the two slice-selective $\pi$/2-pulse and $\pi$-pulse and two diffusion sensitizing gradients placed on the both side of the refocusing $\pi$-pulse and the standard frequency encoding readout was followed. Since the maximum gradient amplitude for the MR system was 15 mT/m the maximum b value was $301.50s/mm^2$. Using the developed LSDI pulse sequence, the diffusion weighted images for the aqueous NaCl solution phantom and triacylglycerol solution phantom calculated from the line scan diffusion weighted images gives the same results within the standard error range (mean diffusivities = $963.90{\pm}79.83({\times}10^{-6}mm^2/s)$ at 0.32 T, $956.77{\pm}4.12({\times}10^{-6}mm^2/s)$ at 1.5 T) and the LSDI images were insensitive to the magnetic susceptibility difference and chemical shift.

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Cerebral Infarction Model in Rat on Magnetic Resonance Imaging (흰 쥐의 뇌경색 병변에 대한 자기공명영상)

  • Jung, Ji-Sung
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.2
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    • pp.55-58
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    • 2011
  • It is important to study using experimental animals for research about stroke. Magnetic Resonance Imaging(MRI) is avaluable diagnosticmethods for stroke diagnosis. The purpose of this research is to know the Magnetic Resonance Imaging(MRI) and histopathological characteristics findings after induction of photothrombotic cerebral infarction in rat brain. Male Sprague-Dawley rats were anesthetized, Rose Bengal dye(20 mg/kg) was intravenously injected. The right sensonrimotor cortex of rat brain was exposed to cold light of 7 mm diameter at a position of 1 mm anterior and 3.5 mm lateral to bregma for 20 min. The post-infarction effects were monitored by T1 weighted and T2 weighted images of brain MRI. Histopathological changes were observed after Hematoxylin & Eosin staining. The lesion appeared clearly high signal intensity area on T2 weighted images(the major axis $7.04{\pm}0.11$ mm, the minor axis $3.08{\pm}0.04$ mm) and also H&E staining was same result. In conclusion, MRI was avaluable diagnostic methods for diagnosis and serial changes of stroke.

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Comparative Study of a Multi-Channel Coils of Magnetic Resonance Imaging(MRI) Signal Intensities under Identical Parameters (동일한 조건의 자기공명검사에서 코일의 채널수 변화에 따른 신호강도의 평가)

  • Son, Soon-Yong
    • The Journal of the Korea Contents Association
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    • v.19 no.6
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    • pp.418-423
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    • 2019
  • The purpose of this study was to determine how the different number of channels of coils were related in the perceived signal intensity under identical parameters and area. Dedicated knee phantoms were scanned consecutively using both of the 16-channel and 8-channel knee coils. The T1 weighted and T2 weighted sequences were acquired using both coils to compare the signal intensities according to the number of channels. As a result, the 16-channel knee coils outperformed the 8-channel knee coils and the signal intensity was significantly increased in both of the T1 and T2 weighted images with the 16-channel coil. In conclusion, it is considered that better signal intensities and more clinical utility can be provided, when coils with more number of channels are used rather than using the coils with smaller number of channels.

How to Combine Diffusion-Weighted and T2-Weighted Imaging for MRI Assessment of Pathologic Complete Response to Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer?

  • Jong Keon Jang;Chul-min Lee;Seong Ho Park;Jong Hoon Kim;Jihun Kim;Seok-Byung Lim;Chang Sik Yu;Jin Cheon Kim
    • Korean Journal of Radiology
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    • v.22 no.9
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    • pp.1451-1461
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    • 2021
  • Objective: Adequate methods of combining T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) to assess complete response (CR) to chemoradiotherapy (CRT) for rectal cancer are obscure. We aimed to determine an algorithm for combining T2WI and DWI to optimally suggest CR on MRI using visual assessment. Materials and Methods: We included 376 patients (male:female, 256:120; mean age ± standard deviation, 59.7 ± 11.1 years) who had undergone long-course CRT for rectal cancer and both pre- and post-CRT high-resolution rectal MRI during 2017-2018. Two experienced radiologists independently evaluated whether a tumor signal was absent, representing CR, on both post-CRT T2WI and DWI, and whether the pre-treatment DWI showed homogeneous hyperintensity throughout the lesion. Algorithms for combining T2WI and DWI were as follows: 'AND,' if both showed CR; 'OR,' if any one showed CR; and 'conditional OR,' if T2WI showed CR or DWI showed CR after the pre-treatment DWI showed homogeneous hyperintensity. Their efficacies for diagnosing pathologic CR (pCR) were determined in comparison with T2WI alone. Results: Sixty-nine patients (18.4%) had pCR. AND had a lower sensitivity without statistical significance (vs. 62.3% [43/69]; 59.4% [41/69], p = 0.500) and a significantly higher specificity (vs. 87.0% [267/307]; 90.2% [277/307], p = 0.002) than those of T2WI. Both OR and conditional OR combinations resulted in a large increase in sensitivity (vs. 62.3% [43/69]; 81.2% [56/69], p < 0.001; and 73.9% [51/69], p = 0.008, respectively) and a large decrease in specificity (vs. 87.0% [267/307]; 57.0% [175/307], p < 0.001; and 69.1% [212/307], p < 0.001, respectively) as compared with T2WI, ultimately creating additional false interpretations of CR more frequently than additional identification of patients with pCR. Conclusion: AND combination of T2WI and DWI is an appropriate strategy for suggesting CR using visual assessment of MRI after CRT for rectal cancer.

The Comparative Analysis Study and Usability Assessment of Fat Suppressed 3D T2* weighted Technique and Fat Suppressed 3D SPGR Technique when Examining MRI for Knee Joint Cartilage Assesment (슬관절 연골 평가를 위한 자기공명영상 검사 시 지방 신호 억제 3D T2* Weighted 기법과 지방 신호 억제 3D SPGR 기법의 비교 및 유용성 평가)

  • Kang, Sung-Jin
    • Journal of the Korean Magnetics Society
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    • v.26 no.6
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    • pp.219-225
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    • 2016
  • In this study, for assessment of degenerative knee joint cartilage disease we acquired images by fat suppressed 3D spoiled gradient recalled (SPGR) and fat suppressed 3D $T2^*$ weighted imaging techniques. To do a quantitative evaluation, the knee joint cartilage was divided into medial femoral cartilage (MFC), medial tibial cartilage (MTC), lateral femoral cartilage (LFC), lateral femoral cartilage (LFC) and patella cartilage (Pat) to measure their respective signal intensity values, signal-to-noise ratio, and contrast-to-noise ratio. As for the measured values, statistical significance between two techniques was verified by using Mann-Whitney U-Test. To do a qualitative evaluation, two radiologists have examined images by techniques after which image artifact, cartilage surface, tissue contrast, and depiction of lesion distinguishing were evaluated based on 4-point scaling (1: bad, 2: appropriate, 3: good, 4: excellent), and based on the result, statistical significance was verified by using Kappa-value Test. 3.0T MR system and HD T/R 8ch knee array coil were used to acquire images. As a result of a quantitative analysis, based on SNR values measured by using two imaging techniques, MFC, LFC, LTC, and Pat showed statistical significance (p < 0.05), but MTC did not (p > 0.05). As a result of verifying statistical significance for measured CNR value, MFC, LFC, and Pat showed statistical significance (p < 0.05), while MTC and LTC did not show statistical significance (p > 0.05). As a result of a qualitative analysis, by comparing mean values for evaluated image items, 3D $T2^*$ weighted Image has indicated a slightly higher value. As for conformance verification between the two observers by using Kappa-value test, all evaluated items have indicated statistically significant results (p < 0.05). 3D $T2^*$ weighted technique holds a clinical value equal to or superior to 3D SPGR technique with respect to evaluating images, such as distinguishing knee joint cartilages, comparing nearby tissues contrast, and distinguishing lesions.

Analysis of Signal Intensity in Choroid Plexuses by Diffusion Weighted Imaging (확산강조영상의 검사기법에 따른 맥락얼기의 신호강도 분석)

  • Oh, JongKap
    • Journal of the Korean Society of Radiology
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    • v.7 no.4
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    • pp.265-269
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    • 2013
  • This report aims at picturing out the clinical usefulness by analyzing the signal intensity in choroid plexuses which produce cerebrospinal fluids by diffusion weighted imaging. At first, subjects were chosen among the patients who showed high in signal intensity by diffusion weighted imaging. The subjects were taken another test by fluid attenuated inversion recovery diffusion weighted echo planer image(FLAIR-DW-EPI) the signals of fluid attenuation. And it was found that there are differences between the signal intensities of the two methods, which showed that the signal intensity in FLAIR-DW-EPI is equal to or low than, that in the Brain. By this, it is felt that it is helpful to diagnose the disease in choroid plexus by testing another more with FLAIR-DW-EPI methods the patients who showed high in signal intensity in choroid plexus by $T2^*$ diffusion weighted echo planer image($T2^*$-DW-EPI).

Focal nodular hyperplasia: Tripie-contrast enhanced MR imaging using gadolinium chelates, mangafodipir trisodium, and ferumoxides

  • Kim, Joo-Hee;Kim, Myeong-Jin;Park, Young-Nyun;Kim, Kyung-Sik;Lee, Jong-Tae;Yoon, Hyung-Sik
    • Proceedings of the KSMRM Conference
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    • 2001.11a
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    • pp.140-140
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    • 2001
  • We present two cases of surgically proven focal nodular hyperplasia whou underwent tri contrast-enhance MR imaging using gadolinium chelates, mangafodipir trisodium, and ferumoxides After the unehanced MR images were obtained, dynamic gadolinium-enhanced T1-weighted imagi were performed, then mangafodipir enhanced and ferumoxides-enhanced images were obtained. In one case, the mass was isointense on both T1- and T2-weighted images on the unehanced M images, iso and slightly hyperintense on ferumoxides-enhanced FSE and GRE images, strong hyperintense on the mangafodipir enhanced and gadolinium enhanced arterial phase images. In th other case, the mass was isointense on T2-weighted and hypointense on T1-weighted image isointense on ferumoxides-enhanced images, and hyperintense on mangafodipir enhanced an gadolinium enhanced arterial phase images. Triple contrast enhanced MR images were useful correctly diagnose these two cases preoperatively.

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Distinction between Intradural and Extradural Aneurysms Involving the Paraclinoid Internal Carotid Artery with T2-Weighted Three-Dimensional Fast Spin-Echo Magnetic Resonance Imaging

  • Lee, Nam;Jung, Jin-Young;Huh, Seung-Kon;Kim, Dong-Joon;Kim, Dong-Ik;Kim, Jin-Na
    • Journal of Korean Neurosurgical Society
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    • v.47 no.6
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    • pp.437-441
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    • 2010
  • Objective : The precise intra- vs. extradural localization of aneurysms involving the paraclinoid internal carotid artery is critical for the evaluation of patients being considered for aneurysm surgery. The purpose of this study was to investigate the clinical usefulness of T2-weighted threedimensional (3-D) fast spin-echo (FSE) magnetic resonance (MR) imaging in the evaluation of unruptured paraclinoid aneurysms. Methods : Twenty-eight patients with unruptured cerebral aneurysms in their paraclinoid regions were prospectively evaluated using a T2- weighted 3-D FSE MR imaging technique with oblique coronal sections. The MR images were assessed for the location of the cerebral aneurysm in relation to the dural ring and other surrounding anatomic compartments, and were also compared with the surgical or angiographic findings. Results : All 28 aneurysms were identified by T2-weighted 3D FSE MR imaging, which showed the precise anatomic relationships in regards to the subarachnoid space and the surrounding anatomic structures. Consequently, 13 aneurysms were determined to be intradural and the other 15 were deemed extradural as they were confined to the cavernous sinus. Of the 13 aneurysms with intradural locations, three superior hypophyseal artery aneurysms were found to be situated intradurally upon operation. Conclusion : High-resolution T2-weighted 3-D FSE MR imaging is capable of confirming whether a cerebral aneurysm at the paraclinoid region is intradural or extradural, because of the MR imaging's high spatial resolution. The images may help in identifying patients with intradural aneurysms who require treatment, and they also can provide valuable information in the treatment plan for paraclinoid aneurysms.