• The Plant Pathology Journal
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• v.35 no.5
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• pp.508-520
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• 2019

Interplay between Cymbidium mosaic virus (CymMV)/Odontoglossum ringspot virus (ORSV) and its host plant Phalaenopsis equestris remain largely unknown, which led to deficiency of effective measures to control disease of P. equestris caused by infecting viruses. In this study, for the first time, we characterized viral small interfering RNAs (vsiRNAs) profiles in P. equestris co-infected with CymMV and ORSV through small RNA sequencing technology. CymMV and ORSV small interfering RNAs (siRNAs) demonstrated several general and specific/new characteristics. vsiRNAs, with A/U bias at the first nucleotide, were predominantly 21-nt long and they were derived predominantly (90%) from viral positive-strand RNA. 21-nt siRNA duplexes with 0-nt overhangs were the most abundant 21-nt duplexes, followed by 2-nt overhangs and then 1-nt overhangs 21-nt duplexes in infected P. equestris. Continuous but heterogeneous distribution and secondary structures prediction implied that vsiRNAs originate predominantly by direct Dicer-like enzymes cleavage of imperfect duplexes in the most folded regions of the positive strand of both viruses RNA molecular. Furthermore, we totally predicted 54 target genes by vsiRNAs with psRNATarget server, including disease/stress response-related genes, RNA interference core components, cytoskeleton-related genes, photosynthesis or energy supply related genes. Gene Ontology classification showed that a majority of the predicted targets were related to cellular components and cellular processes and performed a certain function. All target genes were down-regulated with different degree by vsiRNAs as shown by real-time reverse transcription polymerase chain reaction. Taken together, CymMV and ORSV siRNAs played important roles in interplay with P. equestris by down modulating the expression levels of endogenous genes in host plant.

• The Journal of Korean Academy of Prosthodontics
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• v.27 no.2
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• pp.143-154
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• 1989

The purpose of this study was to investigate the mandibular opening and closing movements at mandibular incisor region and clinical rest position in normal subject using the newly developed electric mandibular movement analyzing device, (M.K.G.-K6 diagnostic system, Myo-tronics Inc. Seattle, WA, U.S.A.) The 58 normal subjects, who were students of the College of Dentistry, Chonbuk National University, were selected according to sampling criteria. The obtained results were as follows: 1. There was no significant difference of distribution of opening and closing movement patterns at mandibular incisor region between male and female. There was significant difference between habitual and maximum movement patterns both in sagittal and frontal plane. 2. Although the percentage of distribution of crossover pattern was highest in all cases, but there were significant differences between patterns only at habitual opening and closing movement in sagittal plane. 3. The mean of maximum opening was $47.29{\pm}4.68mm$ in male and $42.15{\pm}4.95mm$ in female. Therefore the mean of maximum opening was larger in male than in female. 4. The mean of maximum laterotrusion in frontal trajectory was larger to the left than to the right. Also the proportion of left deviation at maximum opening position was larger than that of other cases. 5. The mean of maximum opening and closing velocity was higher in male than in female and the mean of closing velocity was higher than that of opening velocity. Also the amount of separation from the centric occlusion was higher in maximum closing velocity than in maximum opening velocity. 6. Clinical rest position was $1.70{\pm}0.99mm$ inferior, $0.74{\pm}0.57mm$ anterior, $0.99{\pm}0.51mm$ right from centric occlusion and the A/V ratio was 1:2.7.

• Proceeding of EDISON Challenge
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• 2014.03a
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• pp.1-13
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• 2014

Potential Energy Surface(PES)를 양자 계산을 통해 알아내는 것은 화학 반응을 이해하는 데에 큰 도움이 된다. 이를테면 Transition State(TS)의 configuration을 알 수 있고, 따라서 reaction path와 활성화 에너지 값을 예측하여, 진행시키고자 하는 화학반응의 이해를 도울 수 있다. 하지만 PES를 그리기 위해서는 해당 분자의 다양한 configuration에 대한 singlet point energy 계산이 필요하기 때문에, 계산적인 측면에서 많은 비용을 요구한다. 따라서 product와 reactant의 구조와 같은 critical point의 정보를 이용하여 최소한의 configuration을 sampling하여 전체 PES를 재구성하는 기계학습 알고리즘을 개발하여 다차원 PES 상에서의 화학반응의 예측을 가능하게 하고자 한다. 본 연구에서는 Barbaralane의 두 안정화 된 구조의 critical point로 하여 이 주변을 random normal distribution하여, B3LYP/6-31G(d) level의 DFT 계산을 통해 relaxed scanning하여 구조와 에너지를 구하였으며, 이 정보를 Support Vector Regression(SVR) 알고리즘을 적용하여 PES를 재구현하였으며, 반응경로와 TS의 구조 그리고 활성화 에너지를 구하였다. 또한 본 기계학습 알고리즘을 바닥상태에서 일어나는 반응이 아닌, 들뜬 상태와 전자 구조가 변하는 화학반응, avoid crossing, conical intersection과 같은 Non-adiabatic frame에서 일어나는 현상에 적용 가능성을 논하고자 한다.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.30 no.4
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• pp.449-454
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• 1985

In order to search for the semi-dwarf japonica varieties allelic to the semi-dwarf rice cultivar which is controlled by d-t gene, seven dwarf japonica varieties. Reimei, Hoyoku. Shiranui, Kokumasari, M 7. S.224 and S.295 were crossed to the semi-dwarf cultivar, wx 817. wx 817 is known to have semi-dwarf gene d-t. Their F$_1$, F$_2$ and F$_3$ were grown in 1984 and 1985 and culm lengths were measured at harvest. The results are summarized as follows. 1. The F$_2$s of all 7 cross combinations showed normal distribution and no segregation. 2. The range of culm length variation in the F$_3$ was variable depending on the cross combination, but the general pattern was similar in the all 7 crosses. 3. The mean of F$_3$ and parental F$_2$ mean which were selected into short, medium and tall groups were similar and showed no segregation, implying the selection efficiency in F$_2$. 4. From the results of F$_2$ and F$_3$ segregations, it is concluded that the culm length of the 7 semi-dwarf japonicas tested here are controlled by the same major gene d-t although they are modified by different minor genes.

• The Journal of Korean Medicine
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• v.38 no.4
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• pp.55-61
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• 2017

Objectives: In order to accurately measure skin moisture and accumulate normal skin moisture data, analyzing the uncertainty of the skin moisture measurement and establishing standard reference data is essential. It helps to evaluate the skin's condition and has great significance in diagnosis and treatment. In this study, the traceability of the equipment and the uncertainty of the results were analyzed for their potential use in the field of Korean medicine. The data was collected measuring skin moisture on the sole of the foot. Methods: One professional measured the moisture of the adult male's foot 10 times following a determined protocol. The standard uncertainty of repeated measurements was calculated from the mean value of 10 repeated measurements. Ten trainee participants also measured the adult male's foot following a determined protocol. The standard uncertainty by tester was calculated from the value of repeated measurements. Results: As a result of analyzing the difference between the mean and standard uncertainties in both the expert and trainees, it was confirmed that the variance in this study did not satisfy the normal distribution. In addition, the Mann-Whitney U-test was carried out, and it was found that there was no significant difference in the measured values of the two groups. The authorized uncertainty of measurements and traceability of all the equipment was not confirmed. Conclusions: This paper establishes the basis for later measurement-equipment research to provide the objective indicators to approach the dryness of plantar skin from dehydration, the Korean medicine perspective.

• Economic and Environmental Geology
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• v.17 no.1
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• pp.35-47
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• 1984

Combined mineralogical and geochemical studies were made on two hundred eighty one representative samples from uraniferous coaly meta-pelites of the Ogcheon metamorphic terrain. Different mineral occurrence of the areas investigated should be taken into account for chemical processes for uranium extraction. Secondary uranium minerals identified are metauranocircite, metatorbernite and autunite. These are disseminated mostly on the laumontites which infused and filled secondary openings in the coaly matrix, and are often closely associated with iron oxides. The uranium distribution show distinctly log normal. Geochemical correlation coefficient of uranium and organic carbon displays +0.624~+0.796. The relationship of the major components to uranium can be expressed by the following regression equation: Log $(U_3O_8{\times}10^4)$=1.40117-0.00076 (quartz) -0.00118 (muscovite) +0.00235 (biotite) +0.00323 (other silicates) - 0.01114 (apatite) +0.01124 (hematite) +0.00149 (limonite) -0.01823 (opaques)+0.03049 (organic carbon). Uranium in the coaly meta-pelites of the Ogcheon Group was deposited together under same physico-chemical environmental conditions. There is a considerable variation in the ${\delta}^{34}S$ values (11.2~16.8 per mil) of the pyrites from the U-bearing meta-pelites, which implies sedimentary origin. The two U-bearing coaly rocks analyzed have ${\delta}^{13}C$ values between -16.88~-18.00 per mil, which suggests organic.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.2
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• pp.428-434
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• 2015

A new tongue examination model by using color analysis according to the taste division of tongue. The proposed system consists of a tongue image acquisition in a predefined template, taste region segmentation, color distribution analysis and abnormality decision of tongue by color analysis using Hue-Saturation histograms and the part of a mobile application service. We divided 4 basic taste(bitter, sweet, salty and sour) regions and performed color distribution analysis targeting each region under HSI(Hue Saturation Intensity) color model. To minimize the influence of illumination, the histograms of H and S components only except U are utilized. Using the analyzed results, the abnormality is discriminated by the criteria of the histogram range of normal tongues. Finally, a self tongue diagnosis system which can be used anytime and anywhere on mobile environment.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.13 no.3
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• pp.401-408
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• 2006

Purpose: The purpose of this study was to determine the effects of a lower extremity exercise program on muscle strength and flexibility in women with knee osteoarthritis. Method: This study was conducted using a non-equivalent control group pretest-posttest design. The participants were 35 women with knee osteoarthritis. The experimental group performed the lower extremity exercise program, which was an adapted BeHaS exercise program developed by Kim(2006). It consisted of approximately 65-130 minutes per one session, two days a week, for twelve weeks. Lower extremity muscle strength was measured by the Seated Leg Press Machine (TY-H2217, made in Korea), back muscle strength by back muscle strength scale (TKK 5402, made in Japan) and flexibility, by Sit and Reach tester (01285, U.S.A). Data were gathered from September 2005 to March 2006. Frequency, $X^2$ test and t-test were used to analyze the data. SPSS Win 11.0 was used to assist analysis. For normal distribution of data, Kolmogorov-Smirnov test was done. Results: There were statistical differences in the mean strength of both legs together, strength in leg with more pain(p=.044; p=.046), sit and standing time (p=.007), and back strength (p=.021). Conclusion: Based on these results, it can be concluded that a lower extremity exercise program can help improve lower extremity muscle strength in women with osteoarthritis.

• Smart Structures and Systems
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• v.14 no.4
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• pp.719-741
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• 2014

Monitoring surface cracks is important to ensure the health of concrete structures. However, traditional visual inspection to monitor the concrete cracks has disadvantages such as subjective inspection nature, associated time and cost, and possible danger to inspectors. To alter the visual inspection, a complete procedure for automated crack assessment based on adaptive digital image processing has been proposed in this study. Crack objects are extracted from the images using the subtraction with median filter and the local binarization using the Niblack's method. To adaptively. determine the optimal window sizes for the median filter and the Niblack's method without distortion of crack object an optimal filter size index (OFSI) is proposed. From the extracted crack objects using the optimal size of window, the crack objects are decomposed to the crack skeletons and edges, and the crack width is calculated using 4-connected normal line according to the orientation of the local skeleton line. For an image, a crack width nephogram is obtained to have an intuitive view of the crack distribution. The proposed procedure is verified from a test on a concrete reaction wall with various types of cracks. From the crack images with different crack widths and patterns, the widths of cracks in the order of submillimeters are calculated with high accuracy.

• Journal of the Architectural Institute of Korea Structure & Construction
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• v.36 no.1
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• pp.173-178
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• 2020

In this study, we analyzed space heating and domestic hot water(DHW) charges from 2017 to 2018 for 151,206 households in 202 apartment complexes built from 1997 to 2016, in order to evaluate the effectiveness of Korea's insulation standards reinforcement. The applied insulation standards were revised three times(in 1987, 2001 and 2010). We used the Anderson-Darling test to review the normality of the space heating and DHW charges. As a result, each p-value was greater than 0.05 and it followed the normal distribution. The annual average space heating charges per unit area of apartments with the 1987 insulation standards were 5,237￦/㎡a in 2017 and 5,328￦/㎡a in 2018. The heating charges with the 2001 standards were 4,827￦/㎡a in 2017 and 4,817￦/㎡a in 2018. Compared to previous standards(1987 standards), heating charges decreased by 7.8% and 9.6%. Also the heating charges with the 2010 standards were 3,683￦/㎡a in 2017 and 3,734￦/㎡a in 2018. Compared to previous standards(2001 standards), heating charges decreased by 24.3% and 21.5%. On the other hand, compared to each previous standards, DHW charges were decreased by 12.2%, 13.6% or increased by 4.6%, 6.9%, which means there's no correlation between insulation standards reinforcement and DHW charges.