• 제목/요약/키워드: $S1P_1$

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Ebb and Flow 시스템을 이용한 호접란 수경재배시 생장에 미치는 배양액 농도의 영향 (Effect of Nutrient Solution Strength on Growth of Phalaenopsis in an Ebb and Flow System)

  • 안동춘;박선혜;빈철구;정병룡
    • 생물환경조절학회지
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    • 제16권3호
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    • pp.199-204
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    • 2007
  • 배양액 농도가 호접란 미니다화성계 품종 P. amabilis와 P. Taisuco Red Jewel의 유묘와 중간묘의 생장에 미치는 영향을 알아보기 위해 ebb and low system을 이용하여 4개월 재배한 결과는 다음과 같다. 유묘의 경우 엽장과 엽폭이 P. amabilis는 배양액의 EC가 $0.5{\sim}1.0dS{\cdot}m^{-1}$일 때 가장 길었으나 P. Taisuco Red Jewel 배양액의 EC가 $1.5dS{\cdot}m^{-1}$일 때 가장 길었다. 반면에 근장과 근중은 두 품종 모두 배양액의 EC가 $0.5dS{\cdot}m^{-1}$로 낮을 때 가장 무거웠고 이러한 경향은 중간묘에서도 동일하게 나타났다. 잎의 생체중과 건물중은 P. amabilis의 경우 배양액의 EC가 $1.5dS{\cdot}m^{-1}$로 높을 때 가장 무거웠으며, 배양액의 EC가 낮아질수록 잎의 생체중과 건물중은 낮아졌다. 반대로 뿌리의 생체중은 배양액 EC가 $0.5dS{\cdot}m^{-1}$로 낮을 때 가장 무거웠고, 배양액의 EC가 높아질수록 가벼워졌으며, P. Taisuco Red Jewel에서도 같은 경향이었다. 중간묘의 경우 뿌리의 생체중과 건물중이 P. amabilis는 배양액 EC가 $0.5dS{\cdot}m^{-1}$로 낮을 때 가장 높았고, 배양액의 EC가 높아질수록 뿌리의 생체중은 낮아졌다. T/R율과 잎의 엽록소함량은 유묘와 마찬가지로 두 품종 모두 배양액의 EC가 $1.5dS{\cdot}m^{-1}$로 높을 때 가장 높았으며, 배양액의 농도가 낮아질수록 낮아졌다.

덕정리 지진자료를 이용한 한국남동부지역 지각의 P, S파 감쇠구조 연구 (A Study on the Attenuation of High-frequency P and S Waves in the Crust of the Southeastern Korea using the Seismic Data in Deok-jung Ri)

  • 정태웅;사또 하루오
    • 지구물리
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    • 제3권3호
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    • pp.193-200
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    • 2000
  • 지진파가 전달되면 진폭이 감쇠되는 정도를 나타내는 감쇠상수 $Q^{-1}$는 지구내부 물질의 물리적 성질을 나타내는 중요한 척도이며, 구조물의 내진설계에 있어서 지반의 강진동을 정량적으로 예측하기 위해 필수적이다. 경상북도 덕정리에 위치한 지진관측기기에 기록된 80지진과 76단일 관측망 기록자료를 바탕으로 한국남동부의 P, S 실체파 감쇠상수를 Coda확장규격화법에 의해 구하였다. 구하여진 $Q_P^{-1}$$Q_S^{-1}$는 각각 1.5Hz에서 $1{\times}10^{-2}$$9{\times}10^{-3}$, 24 Hz에서 $6{\times}10^{-4}$$5{\times}10^{-4}$로 줄어들고, $Q_P^{-1}=0.01\;f^{-1.07}$$Q_S^{-1}=0.01\;f^{-1.03}$의 강한 주파수 의존성을 보였다.

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Sphingoshine-1-Phosphate Enhances Meiotic Maturation and Further Embryonic Development in Pigs

  • Lee, Hyo-Sang;Koo, Deog-Bon
    • Reproductive and Developmental Biology
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    • 제36권3호
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    • pp.173-181
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    • 2012
  • Sphingosine-1-phosphate (S1P) has a many function involved proliferation, differentiation and survival of many cells. In this study, to investigate whether S1P improve the developmental competence of porcine embryos, 50 nM of S1P were supplemented during in vitro maturation (with EGF or without EGF) medium and/or in vitro culture (IVC) medium. Addition of S1P was significantly increased the rate of oocytes reaching metaphase II (MII) compared to the control (83.5 vs. 64.1%) in without EGF medium, but not with EGF medium (89.5 vs. 84.6%). When treated with $1{\mu}M$ of N1N-dimethylsphingosine (DMS), a sphingosine kinase inhibitor which is blocked endogenous generation of S1P, the meiotic progression rates to MII stage (without EGF: 45.2 and with EGF: 66.7%) were significantly decreased and degeneration rates (without EGF: 51.2 and with EGF: 30.1%) were increased in both medium compared to control group during IVM periods. Also, the rates of blastocyst formation was significantly increased in the S1P treated group compared to control group (29.0 vs. 19.2%) of EGF supplemented medium, whereas there were no effect in the EGF free medium (9.0 vs. 10.5%). After 12 h IVM, the phosphorylation of ERK1 and ERK2, which is major signaling pathway of MAP kinase, were increased in the S1P group than that of control or DMS group. When supplemented of S1P during IVC, the rates of blastocyst formation and total cell number (30.2% and 40.6) were significantly increased in S1P-treated group compared with control (20.1% and 32.5), DMS (12.3% and 25.1), and S1P plus DMS group (24.7% and 33.6). The percentage of apoptosis nuclei in the S1P group was significantly decreased than other groups. Also, the rates of blastocyst formation (26.7 vs. 14%) and total cell number (42.8 vs. 32.5) were significantly increased in the S1P group than those of control group when S1P added during the entire IVM and IVC periods. Taken together, our results indicate that S1P supplementation in IVM and/or IVC medium affects beneficial effect of meiotic maturation and subsequent developmental competence of porcine embryos.

Synthesis of Nucleophilic Adducts of Thiols (Ⅰ). Addition of Cysteine to $\beta$-Nitrostyrene Derivatives

  • Kim, Tae-Rin;Choi, Sung-Yong
    • Bulletin of the Korean Chemical Society
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    • 제2권4호
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    • pp.125-129
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    • 1981
  • The addition reactions of cysteine without blocking amino and carboxyl groups to substituted and unsubstituted ${\beta}$-nitro-styrene derivatives were investigated. ${\beta}$-Nitrostyrene(1a), p-methyl-${\beta}$-nitrostyrene(1b), 3,4,5-trimethoxy-$[\beta}$ -nitrostyrene(1c), $[\varpi}$-3,4-methylenedioxy-${\beta}$ -nitrostyrene(1d), o-, m- and p-chloro-${\beta}$ -nitrostyrene (1e, 1f, 1g) and o-, m- and p-methoxy-${\beta}$-nitrostyrene (1h, 1i, 1j) easily undergo addition reactions with cysteine to form S-(2-nitro-1-phenylethyl)-L-cysteine(3a), S-[2-nitro-1-(p-methyl)phenyl-ethyl]-L-cysteine(3b), S-[2-nitro-1-(3',4',5'-trimethoxy) phenylethyl]-L-cysteine(3c), S-[2-nitro-1-($[\vatpi}$ -3',4'-methylenedioxy)phenylethyl]-L-cysteine(3d), S-[2-nitro-1-(o-chloro)phenylethyl]-L-cysteine(3e), S-[2-nitro-1-(m-chloro)-phenylethyl]-L-cysteine(3f), S-[2-nitro-1-(p-chloro)phenylethyl]-L-cysteine(3g), S-[2-nitro-1-(o-methoxy)phenylethyl]-L-cysteine(3h), S-[2-nitro-1-(m-methoxy)phenylethyl]-L-cysteine(3i) and S-[2-nitro-1-(p-methoxy)phenylethyl]-L-cysteine(3j), respectively. The structure of adducts were confirmed by means of UV-spectrum, IR-spectrum, molecular weight measurement and elemental analysis. The various factors effecting the yield of cysteine adducts to ${\beta}$-nitrostyrene derivatives were also studied.

POSITIVE SOLUTIONS FOR MULTIPOINT BOUNDARY VALUE PROBLEMS WITH ONE-DIMENSIONAL p-LAPLACIAN OPERATOR

  • Xu, Fuyi;Meng, Zhaowei;Zhao, Wenling
    • Journal of applied mathematics & informatics
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    • 제26권3_4호
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    • pp.457-469
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    • 2008
  • In this paper, we study the existence of positive solutions for the following nonlinear m-point boundary value problem with p-Laplacian: $\{{{{(\phi_p(u'))'\;+\;f(t,u(t))=0, \;0<t<1,} \atop u'(0)={\sum}{^{m-2}_{i=1}}\;a_iu'(\xi_i),} \atop u(1)={\sum}{^k_{i=1}}\;b_iu(\xi_i)\;-\;{\sum}{^s_{i=k+1}}\;b_iu(\xi_i)\;-\;{\sum}{^{m-2}_{i=s+1}}\;b_iu'(xi_i),}$ where ${\phi}_p(s)$ is p-Laplacian operator, i.e., ${\phi}_p(s)=\mid s\mid^{p-2}s$, p>1, ${\phi}_q\;=\;({\phi}_p)^{-1}$, $\frac{1}{p}+\frac{1}{q}=1$, $1\;{\leq}\;k\;{\leq}\;s\;{\leq}m\;-\;2$, $b_i\;{\in}\;(0,+{\infty})$ with $0\;<\;{\sum}{^k_{k=1}}\;b_i\;-\;{\sum}{^s_{i=k+1}}\;b_i\;<\;1$, $0\;<\;{\sum}{^{m-2}_{i=1}}\la_i\;<\;1$, $0\;<\;{\xi}_1\;<\;{\xi}_2\;<\;{\cdots}\;<\;{\xi}_{m-2}\;<\;1$, $f\;{\in}\;C([0,\;1]\;{\times}\;[0,\;+{\infty}),\;[0,\;+{\infty}))$. We show that there exists one or two positive solutions by using fixed-point theorem for operator on a cone. The conclusions in this paper essentially extend and improve the known results.

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독일어의 신체부위 "손" 관련 관용구의 결합가 연구 (Zur Valenz deutscher verbaler Somatismen mit der Komponente ${\lceil}hand{\rfloor}$)

  • 김수남
    • 한국독어학회지:독어학
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    • 제4집
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    • pp.1-27
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    • 2001
  • 이 글의 목적은 독일어 신체어휘 관련 관용구들 가운데 ${\lceil}$Duden Band 11${\rfloor}$에 수록된 108개의 $\lceil$$\rfloor$ 관련 관용구를 대상으로 이들의 형태$\cdot$통사구조를 파악하고, 그들을 모형화하는 것이다. 우리는 연구 대상을 문장에서 결합가 보유어로서 술어의 기능을 하는 관용구에 한정했다. 우리는 $\lceil$$\rfloor$ 관련 관용구를 보충어의 수와 형태에 따라 크게 세 가지 부류, 즉 1가, 2가, 3가의 관용구로 구분하였다 보충어의 형태는 명사구(Sn, Sd, Sa)와 전치사구(pS)에 한정했으며 문장형태의 보충어, 예를 들어 부문장(NS)과 부정사문(Inf) 형태는 고려하지 않았다. 이들이 보충어로 간주될 수 있는지의 여부는 아직 더 많은 연구를 필요로 하기 때문에 다음 과제로 남겨두었다. 일차적으로 외적 결합가($\"{a}u{\beta}ere\;Valenz)$에 따라, 이차적으로는 내적 결합가(innere Valenz)에 따라 108개의 $\lceil$$\rfloor$ 관련 관용구를 분석한 결과 우리는 다음과 같은 형태$\cdot$통사적 문형을 얻을 수 있었다. $\cdot$ 1가 동사 관용구: 1) PL-Sn : (1) PL[VPL - Sa] - Sn (2) PL(VPL - pS) - Sn (3) PL[VPL - Sa - pS] - Sn (4) PL[VPL - pS - pS] - Sn Sondergruppen: PL[VPL - Sa - Inf] - Sn PL[VPL - pS - Inf] - Sn 2) PL - Sd: (1) PL[VPL - Sn] - Sd (2) PL[VPL - Sn(es) - pS] - Sd $\cdot$ 2가 동사 관용구1) PL - Sn - Sd: (1) PL[VPL - Sa] - Sn - Sd (2) PL[VPL - pS] - Sn - Sd (3) PL[VPL - Sa - pS) - Sn - Sd 2) PL - Sn - pS: (1) PL[VPL - Sa] - Sn - pS (2) PL[VPL - pS] - Sn - pS (3) PL(VPL - Sa - pS) - Sn - pS 3) PL[VPL - pS) - Sn -Sa $\cdot$ 3가 동사 관용구: (1) PL[VPL - pS] - Sn - Sd - Sa (2) PL[VPL - pS] - Sn - Sa - pS (3) PL[VPL - Sa] - Sn - Sd - pS 이러한 분류가 보여주듯이, 독일어에는 1가, 2가, 3가의 관용구가 있으며, 구조 외적으로 동일한 통사적 결합가를 갖는다 하더라도 구조 내적 성분구조가 다르다는 것을 알 수 있다. 우리는 이 글이 외국어로서의 독일어를 배우는 이들에게 독일어의 관용구를 보다 올바르게 이해할 수 있는 방법론적인 토대를 제공함은 물론, (관용어) 사전에서 외국인 학습자를 고려하여 관용구를 알기 쉽게 기술하는 데 도움을 줄 수 있기를 바란다.

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A NEW CHARACTERIZATION OF ALTERNATING AND SYMMETRIC GROUPS

  • ALAVI S. H.;DANESHKHAW A.
    • Journal of applied mathematics & informatics
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    • 제17권1_2_3호
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    • pp.245-258
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    • 2005
  • In this paper we prove that the alternating groups A_n, for n = p, p+1, p+2 and symmetric groups $S_n$, for n = p, p+1, where p$\ge$3 is a prime number, can be uniquely determined by their order components. As one of the important consequence of this characterization we show that the simple groups An, where n = p, p+1, P+2 and p$\ge$3 is prime, satisfy in Thompson's conjecture and Shi's conjecture.

Sphingosine-1-Phosphate (S1P)가 이식지방의 생존에 미치는 영향 (The Effect of Sphingosine-1-Phosphate in Survival of Grafted Fat Tissues)

  • 윤동주;최수종;최치원;남수봉;배용찬
    • Archives of Plastic Surgery
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    • 제37권6호
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    • pp.726-731
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    • 2010
  • Purpose: Autologous fat grafting is a popular procedure for the correction of the soft tissue depression and deformity. But there are several issues required to be carefully considered in relation to this procedure, mainly about the unpredictability and the low survival rate of the grafted fat due to absorption and partial necrosis. Sphingosine-1-phosphate (S1P) is a lysophospholipid mediator that has been proposed to promote angiogenesis and to regulate the differentiation of adipose derived stromal cells (ASCs). In this study, we analyzed the viability of the grafted fat tissue mixed with S1P into each 12 nude mice (cann.cg-fox1nu/crlori) compared to the group of mice grafted fat tissue only. Methods: Human aspirated fat was grafted subcutaneously into the backs of 8-week-old nude mice with or without S1P. Eight weeks later, the grafted fat was harvested and the weight and volume were checked. The fat was stained with hematoxylin-eosin and 4',6-diamidino-2-phenylindole. Results: S1P group weighed significantly more than the control group (p=0.009), and the volume from the S1P group was considerably larger than that of the control group (p=0.004) either. In histological features, the surviving layer of the S1P group was thicker than the control group and microvasculature appeared to be prominent in the S1P group, especially in the outer layers. Conclusion: These findings suggest that S1P plays a vital role in the soft tissue augmentation, potentially providing a novel point of the control in adipose tissue for microfat graft.

Synthesis of Nucleophilic Adducts of Thiols (Ⅳ). Addition of Glutathione to $\beta$-Nitrostyrene Derivatives

  • Kim, Tae-Rin;Choi, Sung-Yong;Choi, Won-Sik
    • Bulletin of the Korean Chemical Society
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    • 제4권2호
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    • pp.92-95
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    • 1983
  • The addition products of glutathione to ${\beta}$ -nitrostyrene derivatives were synthesized. ${\beta}$ -Nitrostyrene (1a), p-methyl-${\beta}$-nitrostyrene (1b), 3,4,5-trimethoxy-${\beta}$-nitrostyrene (1c), o-, m- and p-chloro-${\beta}$-nitrostyrene (1e, 1f, 1g) and o-, m- and p-methoxy-${\beta}$-nitrostyrene (1h, 1i, 1j) undergo addition reactions with glutathione to form S-(2-nitro-1-phenylethyl)-L-glutathione (5a), S-[2-nitro-1-(p-methyl)phenylethyl]-L-glutatione (5b), S-[2-nitro-1-(3', 4', 5'-trimethoxy)phenylethyl]-L-glutathione (5c), S-[2-nitro-1-(o-chloro)phenylethyl]-L-glutathione (5e), S-[2-nitro-1-(m-choro)phenylethyl]-L-glutathione (5f), S-[2-nitro-1-(p-chloro)phenylethyl]-L-glutathione (5g), S-[2-nitro-x-(o-methoxy)-phenylethyl]-L-glutathion e(5h), S-[2-nitro-x-(m-methoxy)phenylethyl]-L-glutathion e (5i), and S-[2-nitro-1-(p-methoxy)phenylethy])-L-glutathione (5j), respectively. The structure of adducts were identified by UV and IR-spectra, molecular weight measurement, and elemental analysis.

POSITIVE SOLUTIONS FOR A THREE-POINT FRACTIONAL BOUNDARY VALUE PROBLEMS FOR P-LAPLACIAN WITH A PARAMETER

  • YANG, YITAO;ZHANG, YUEJIN
    • Journal of applied mathematics & informatics
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    • 제34권3_4호
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    • pp.269-284
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    • 2016
  • In this paper, we firstly use Krasnosel'skii fixed point theorem to investigate positive solutions for the following three-point boundary value problems for p-Laplacian with a parameter $({\phi}_P(D^{\alpha}_{0}+u(t)))^{\prime}+{\lambda}f(t, u(t))=0$, 0$D^{\alpha}_{0}+u(0)=u(0)=u{\prime}{\prime}(0)=0$, $u^{\prime}(1)={\gamma}u^{\prime}(\eta)$ where ϕp(s) = |s|p−2s, p > 1, $D^{\alpha}_{0^+}$ is the Caputo's derivative, α ∈ (2, 3], η, γ ∈ (0, 1), λ > 0 is a parameter. Then we use Leggett-Williams fixed point theorem to study the existence of three positive solutions for the fractional boundary value problem $({\phi}_P(D^{\alpha}_{0}+u(t)))^{\prime}+f(t, u(t))=0$, 0$D^{\alpha}_{0}+u(0)=u(0)=u{\prime}{\prime}(0)=0$, $u^{\prime}(1)={\gamma}u^{\prime}(\eta)$ where ϕp(s) = |s|p−2s, p > 1, $D^{\alpha}_{0^+}$ is the Caputo's derivative, α ∈ (2, 3], η, γ ∈ (0, 1).