• Childhood Kidney Diseases
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• v.3 no.1
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• pp.27-34
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• 1999

Purpose: This study was designed to investigate the changes in soluble interleukin-2 receptor (sIL-2R) level in sera and urines of children with primary nephrotic syndrome, eliminating the confounding effects of age, proteinuria, and steroid treatment. Methods: Soluble IL-2R was measured by ELISA in sera and urines from patients with minimal change nephrotic syndrome or focal segmental glomerulosclerosis as well as from healthy controls. The serum levels and urinary sIL-2R/creatinine ratios were compared between control group and the 12 patient groups divided by their ages (0-1, 2-4, over 5 years), and presence or absence of proteinuria and/or steroid treatment (PU+Tx-, PU+Tx+, PU-Tx+, PU-Tx-). Results: Though the differences were not statistically significant probably because of the small numbers, serum sIL-2R levels seemed to be higher in younger age groups both in patients and control group. Nephrotic children did not show higher serum levels than normal children. Among the patients, proteinuric condition seemed to raise and steroid treatment tended to suppress the serum sIL-2R levels. Urinary sIL-2R/creatinine ratios were higher in younger age groups, more significantly in patients (P<0.001). Proteinuria and steroid treatment affected the urinary sIL-2R/creatinine ratios by the same way as the serum sIL-2R levels. Serum sIL-2R levels and urinary sIL-2R/creatinine ratios were not different between groups of different histologic findings or steroid responsiveness (P>0.05). Conclusion: Serum sIL-2R levels and the urinary sIL-2R/creatinine ratios were higher in younger age, and they were not higher in nephrotic patients compared to control group. The patients in relapse showed higher levels, while the levels were suppressed with steroid treatment. In proteinuric state, urinary sIL-2R/creatinine ratios reflected serum sIL-2R levels.

• International Commerce and Information Review
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• v.16 no.5
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• pp.51-66
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• 2014

The relationship study between SMEs' R&D and business performance is important research subject. The objective of this paper is to evaluate whether the effectiveness of government's R&D subsidy for SMEs is supported. The positive perspective is that the support policy stimulates the SMEs innovation activities including R&D and thus contributes to the performance, but the negative view is that the support policy rather decreases the firm's own R&D investment and thus the result is not necessarily promising. This paper is to evaluate the effectiveness of government subsidy on SMEs' R&D. This study suggested DID and Random Effect Models for analysis using the panel data of 2,807 SMEs in manufacturing sector. The data was collected from the 'Survey on SMEs Technology & R&D 2011' conducted by Korea Federation of Small and Medium Business. The results are as follows. First, government's subsidy has crowded out 4.7% of beneficiary's internal R&D investment. Second, government's subsidy has increased 27.3% of beneficiary's R&D intensity in spite of 4.7% internal R&D investment reduction. Third, government's subsidy didn't have a relationship with firm performance but the R&D intensity made positive influence on the firm performance. Finally, R&D intensity has increased the 6.7% of firm performance. These results mean that government's subsidy give a positive impact on SMEs' performance through R&D intensity with relatively small crowding-out effect.

• The Mathematical Education
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• v.12 no.2
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• pp.5-12
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• 1974

단위원을 가지는 하환환에 있어서의 Prime Spectrum에 관하여 다음 세가지 사실을 증명하였다. 1. X를 환 R의 prime spectrum, C(X)를 X에서 정의되는 실연적함수의 환, X를 C(X)의 maximal spectrum이라 하면 X는 C(X)의 prime spectrum의 부분공간으로서의 한 T-space로 된다. N을 환 R의 nilradical이라 하면, R/N이 regula 이면 X와 X는 위상동형이다. 2. f: R$\longrightarrow$R'을 ring homomorphism, P를 R의 한 Prime ideal, $R_{p}$, R'$_{p}$를 각각 S=R-P 및 f(S)에 관한 분수환(ring of fraction)이라 하고, k(P)를 local ring $R_{p}$의 residue' field라 할 때, R'의 prime spectrum의 부분공간인 $f^{*-1}$(P)는 k(P)(equation omitted)$_{R}$R'의 prime spectrum과 위상동형이다. 단 f*는 f*(Q)=$f^{-1}$(Q)로서 정의되는 함수 s*:Spec(R')$\longrightarrow$Spec(R)이다. 3. X를 환 S의 prime spectrum, N을 R의 nilradical이라 할 때, 다음 네가지 사실은 동치이다. (1) R/N 은 regular 이다. (2) X는 Zarski topology에 관하여 Hausdorff 공간이다. (3) X에서의 Zarski topology와 constructible topology와는 일치한다. (4) R의 임의의 원소 f에 대하여 f를 포함하지 않는 R의 prime ideal 전체의 집합 $X_{f}$는 Zarski topology에 관하여 개집합인 동시에 폐집합이다.폐집합이다....

• The Korean Journal of Applied Statistics
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• v.25 no.5
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• pp.757-773
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• 2012

Traditional value at risk(S-VaR) has a difficulity in predicting the future risk of financial asset prices since S-VaR is a backward looking measure based on the historical data of the underlying asset prices. In order to resolve the deficiency of S-VaR, an economic value at risk(E-VaR) using the risk neutral probability distributions is suggested since E-VaR is a forward looking measure based on the option price data. In this study E-VaR is estimated by assuming the generalized gamma distribution(GGD) as risk neutral density function which is implied in the option. The estimated E-VaR with GGD was compared with E-VaR estimates under the Black-Scholes model, two-lognormal mixture distribution, generalized extreme value distribution and S-VaR estimates under the normal distribution and GARCH(1, 1) model, respectively. The option market data of the KOSPI 200 index are used in order to compare the performances of the above VaR estimates. The results of the empirical analysis show that GGD seems to have a tendency to estimate VaR conservatively; however, GGD is superior to other models in the overall sense.

• The Korean Journal of Applied Statistics
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• v.17 no.2
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• pp.269-280
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• 2004

We explore the selection of r and s that provides improvement over the Wilcoxon scores under the asymmetric distributions we encounter in practice. We select 0 〈 r 〈 1, s 〉 1 for right-skewed distribution and r 〉 1,0 〈 s 〈 1 for left-skewed distributions from the perspective plots. We also study the association between the desirable r and s and the test statistic for skewness.

• Journal of applied mathematics & informatics
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• v.32 no.1_2
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• pp.55-60
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• 2014

In this paper, we will obtain Marcinkiewicz's type limit laws for fuzzy random sets as follows : Let {$X_n{\mid}n{\geq}1$} be a sequence of independent identically distributed fuzzy random sets and $E{\parallel}X_i{\parallel}^r_{{\rho_p}}$ < ${\infty}$ with $1{\leq}r{\leq}2$. Then the following are equivalent: $S_n/n^{\frac{1}{r}}{\rightarrow}{\tilde{0}}$ a.s. in the metric ${\rho}_p$ if and only if $S_n/n^{\frac{1}{r}}{\rightarrow}{\tilde{0}}$ in probability in the metric ${\rho}_p$ if and only if $S_n/n^{\frac{1}{r}}{\rightarrow}{\tilde{0}}$ in $L_1$ if and only if $S_n/n^{\frac{1}{r}}{\rightarrow}{\tilde{0}}$ in $L_r$ where $S_n={\Sigma}^n_{i=1}\;X_i$.

• Journal of Microbiology and Biotechnology
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• v.18 no.5
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• pp.815-820
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• 2008

Two culture-independent methods, namely ribosomal DNA libraries and denaturing gradient gel electrophoresis (DGGE), were adopted to examine the microbial community of a Malaysian light crude oil. In this study, both 16S and 18S rDNAs were PCR-amplified from bulk DNA of crude oil samples, cloned, and sequenced. Analyses of restriction fragment length polymorphism (RFLP) and phylogenetics clustered the 16S and 18S rDNA sequences into seven and six groups, respectively. The ribosomal DNA sequences obtained showed sequence similarity between 90 to 100% to those available in the GenBank database. The closest relatives documented for the 16S rDNAs include member species of Thermoincola and Rhodopseudomonas, whereas the closest fungal relatives include Acremonium, Ceriporiopsis, Xeromyces, Lecythophora, and Candida. Others were affiliated to uncultured bacteria and uncultured ascomycete. The 16S rDNA library demonstrated predomination by a single uncultured bacterial type by >80% relative abundance. The predomination was confirmed by DGGE analysis.

• The Journal of the Petrological Society of Korea
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• v.25 no.4
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• pp.311-324
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• 2016

The characteristics of the rock cleavage in Jurassic granite from Geochang were analysed. The evaluation for three quarrying planes and three rock cleavages was performed using the parameters such as (1) reduction ratio between the value of spacing and the value of length, (2) microcrack spacing frequency(N), (3) total spacing($1mm{\geq}$), (4) exponential constant(a), (5) magnitude of exponent(${\lambda}$), (6) mean spacing($S_{mean}$), (7) difference value($S_{mean}-S_{median}$) between mean spacing and median spacing($S_{median}$) and (8) density of spacing. Especially the close dependence between the above spacing parameters and the parameters from the spacing-cumulative frequency diagrams was derived. The discrimination factors representing three quarrying planes and three rock cleavages were acquired through these mutual contrast. The analysis results of the research are summarized as follows. First, the reduction ratios of frequency(N), mean value, median value, the above difference value($S_{mean}-S_{median}$) and density for three rock cleavages are in orders of G(grain, (G1 + G2)/2) < H(hardway, (H1 + H2)/2) < R(rift, (R1 + R2)/2), H < G $\ll$ R, H < G $\ll$ R, H < G < R and H < G $\ll$ R. The values of the above five parameters for three planes show the various orders of R'(rift plane) $\ll$ H'(hardway plane) < G'(grain plane), R' $\ll$ G' < H', R' < H' < G', R' < G' < H' and R' $\ll$ H' < G', respectively. Second, the values of (I) parameters(2, 3, 4 and 5) and (II) parameters(6, 7 and 8) are in orders of (I) H < G < R and (II) R < G < H. On the contrary, the values of the above two groups(I~II) of parameters for three planes show reverse orders. Third, to review the overall characteristics of the arrangement among the six diagrams, these diagrams show an order of R2 < R1 < G2 < G1 < H2 < H1 from the related chart. In other words, above six diagrams can be summarized in order of rift(R1 + R2) < grain(G1 + G2) < hardway(H1 + H2). These results indicate a relative magnitude of rock cleavage related to microcrack spacing. Especially, two parameters for each diagram, the above difference value($S_{mean}-S_{median}$) and mean spacing, could provide advanced information for prediction the order of arrangement among the diagrams. Finally, the general chart for three planes and three rock cleavages were made. From the related chart, three exponential straight lines for three rock cleavages show an order of R(R1 + R2) < G(G1 + G2) < H(H1 + H2). On the contrary, three lines for three planes show an order of H'(R2 + G2) < G'(R1 + H2) < R'(G1 + H1). Consequently, correlation of the mutually reverse order between three planes and three rock cleavages can be drawn from the related chart.

• Bulletin of the Korean Mathematical Society
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• v.59 no.6
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• pp.1387-1408
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• 2022

Let R be a commutative ring with a non-zero identity, S be a multiplicatively closed subset of R and M be a unital R-module. In this paper, we define a submodule N of M with (N :_R M)∩S = ∅ to be weakly S-prime if there exists s ∈ S such that whenever a ∈ R and m ∈ M with 0 ≠ am ∈ N, then either sa ∈ (N :_R M) or sm ∈ N. Many properties, examples and characterizations of weakly S-prime submodules are introduced, especially in multiplication modules. Moreover, we investigate the behavior of this structure under module homomorphisms, localizations, quotient modules, cartesian product and idealizations. Finally, we define two kinds of submodules of the amalgamation module along an ideal and investigate conditions under which they are weakly S-prime.

• Tuberculosis and Respiratory Diseases
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• v.41 no.2
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• pp.135-143
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• 1994

Background: The cell mediated immunity has an important role in the pathogenesis of tuberculosis. sIL-2R has been known as a sensitive marker of T lymphocyte activation Elevated serum levels of sIL-2R have been found in patients with lymphoproliferative disorders, organ transplantation, autoimmune diseases, and various granulomatous diseases. Elevated levels of sIL-2R have been also found in the serum and pleural fluid of the patients with tuberculosis. To evaluate the diagnostic value of sIL-2R in the differentiation of tuberculous pleurisy and nontuberculous pleurisy. We measured the level of sIL-2R in the sera and pleural fluids of 12 patients with tuberculous pleurisy and 32 patients with nontuberculous pleurisy. Method: Samples of pleural fluid and serum were centrifuged at 2500 rpm for 10 min to remove cell pellets. Soluble IL-2R was measured with a sandwitch enzyme immunoassay using the Cellfree(r) Interleukin-2 Receptor Test kit(T-cell science,Inc. Cambridge, MA). Results: The results obtained were as follows: 1) The sIL-2R level in pleural fluid of the patients with tuberculous pleurisy was higher than that of patients with nontuberculous pleurisy(P<0.005). 2) When the sIL-2R level above 5,000 u/ml in pleural fluid was used as the cut-off value to diagnose tuberculous pleurisy, it had a sensitivity of 84.6% and a specificity of 90.9%. 3) The sIL-2R level in the sera of the patients with tuberculous pleurisy was higher than that of patients with bacterial pleural effusions and normal control group(P<0.05) and there was no difference of levels compared with malignant pleural effusions and transudative pleural effusions(P>0.05). 4) In patients with tuberculous pleurisy, the mean concentration of sIL-2R in pleural fluid was higher than that in serum(P<0.005). Conclusion: These findings suggest that the measurement of elevated levels of pleural fluid sIL-2R in tuberculous pleurisy may be useful in the differential diagnosis between patients with tuberculous pleurisy and nontuberculous pleurisy.