• 제목/요약/키워드: $P_388$

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WMSN에서 비디오 영상의 특성을 고려하여 적응적 타임아웃 스케줄링을 적용한 QoS 보장 기법 (Technique of ensuring QoS by applying adaptive timeout scheduling and considering characteristic of video image in WMSN)

  • 박종우;정승완;백장운;서대화
    • 한국정보과학회:학술대회논문집
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    • 한국정보과학회 2012년도 한국컴퓨터종합학술대회논문집 Vol.39 No.1(D)
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    • pp.387-388
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    • 2012
  • 최근 무선 멀티미디어 센서 네트워크(WMSN : Wireless Multimedia Sensor Network)에서 비디오 영상을 전송하는데 있어 그 특성을 고려하지 않은 전송 방법으로 인하여 영상 정보에 대한 신뢰도가 낮다는 문제점이 있다. 본 논문은 WMSN에서 비디오 프레임의 구성요소인 I, P, B 픽처의 특성에 따라 타임아웃을 동적으로 설정하여 노드와 노드간의 패킷 수신율을 증가시켜 전체 서비스의 QoS를 제공하고, 이벤트를 감지하여 특정 구간의 영상 정보를 제공받을 수 있는 기법을 제안한다.

Streptomyces floridae SHS-1372가 생산하는 항암항생물질 HS-1의 특성 (Characteristics of Antitumor Antibiotics HS-1 from a Stveptomyces JIoridiae SHS-1372)

  • 하상철;홍순덕
    • 한국미생물·생명공학회지
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    • 제22권2호
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    • pp.169-174
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    • 1994
  • Antitumor antibiotic HS-1 was purified from the culture broth of a streptomyces floridae SHS-1372 which had been isolated from soil, by solvent extraction, silica gel column chromatography and gel filtration. It was confirmed that HS-1 was active against gram positive bacteria and cancer cells(K562, P388, MCF-7, HT-29). Through the analysis of UV spectrum, melting point, IR spectrum, FAB-MS, $_{1}$H-NMR, $_{13}$C-NMR, 2D-NMR spectra, HS-1 could be identified sa the actinomycin X$_{2}$ antibiotics containing actinocine chromophore and peptides consisted of threonine, proline, methylvaline, sarcosine, D-valine and 4-ketoproline.

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Isoguanosine과 Berberine 1 : 1 혼합물의 항암효과 (Anti-tumor Activity of Isoguanosine and Berberine 1 : 1 mixture)

  • 김정한;이상준;한영복;문정조;김종배
    • 약학회지
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    • 제38권2호
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    • pp.174-178
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    • 1994
  • Isoguanosine and berberine 1:1 mixture[l:[1(mole:mole)] has been prepared and evaluated by measuring antitumor effects against various tumor cell lines in culture and in mice. We reported that the synergistic effect of isoguanosine and berberine mixture has been revealed compared with each of isoguanosine and berberine increased by $3{\sim}8$ times than that of each components in various tumor cell lines in vitro. The most effective dose of isoguanosine and berberine mixture was 60 mg/kg/day in mice bearing S-180 solid tumor, the %(1-T/C) values were 70%. Against the P-388 leukemia, isoguanosine-berberine mixture was the most effective at the dose of 60 mg/kg/day, the %T/C values were 163%.

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항암활성을 갖는 백금 착체의 합성과 신독성 (Synthesis and Nephrotoxicity of Pt Complexes as Antitumor Agent)

  • 이근임;황규자
    • 약학회지
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    • 제38권6호
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    • pp.627-636
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    • 1994
  • Several Pt(II) and Pt(IV) complexes of N,N'-bis(2-hydroxyethyl)ethylenediamine(2-HEen) and N,N'-bis(2-chloroethyl) ethylenediamine(2-CEen) as carrier ligand were prepared. Water soluble Pt complexes were also synthesized by modification of leaving groups. The cytotoxicity of these compounds against leukemia L1210 and P388 cell in vitro were examined. The Pt complexes containing 2-CEen showed more effective cytotoxicity than those containing 2-HEen. Through the nephrotoxicity tests on the primary cultured proximal tubular cells of rabbit kidney and human kidney cells in vitro, Pt complexes with 2-CEen showed higher than those with 2-HEen which were consistent with cytotoxicity but showed very low nephrotoxicity compared with cisplatin. Also the values of BUN and creatinine in serum of Pt complexes were reduced remarkably compared with cisplatin, therefore it can be concluded that new Pt complexes seems to have much lower nephrotoxicity than cisplatin.

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Cytotoxic Chemical Constituents from the Mushroom of Pholiota adiposa

  • Chung, Ill-Min;Kong, Won-Sik;Lee, Oh-Kyu;Park, Jeong-Sik;Ahmad, Ateeque
    • Food Science and Biotechnology
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    • 제14권2호
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    • pp.255-258
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    • 2005
  • The compounds, 1-Linoleic-2-olein (1), stigmasterol (2), 1,4-glucopyranosyl-1',4'-glucopyranosyl-1",4"-glucopyranoside (3), 2',3'-diphosphoryl-1'-propanoxy-${\beta}$-D-glucopyranoside (4), 1-Linoleic-3-olein (5), l-(N,N,N-trimethyl ethyl amino phosphoryl)-2,3-dilinolein ion (6) and glyceryl phosphate (7) were isolated and identified from the Mushroom of Pholiota adiposa for the first time by column chromatography, TLC, UV, IR, $^1H$ and $^{13}C$ NMR, EI-MS, and FAB-MS. The compounds 1 and 2 were found to have weak cytotoxicity against P388 murine leukemia cells. However, the compounds 6 and 7 did not show any cytotoxicity.

生物活性 スクリニングによる天然物資源からの 抗腫瘍活性物質 (Isolation and Structural Determination of Antitumor Substanes from Natural Products using Bio-active Screening Tests)

  • Takeya, Koichi;Itokawa, Hideji
    • 한국자원식물학회지
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    • 제6권1호
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    • pp.45-51
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    • 1993
  • Many plants collected at Japan, China, Korea, Imdonesia and South America were applied to antitumor and / or cytotoxic screening tests against Sarcoma 180 ascites in mice and / or V-79, KB, P388 cultured cells. On the course of these screening tests, alcoholic extracts of Forsythia viridissima (Oleaceae), Eurycoma longifolia(Simaroubaceae), Rubia cordifolia and R. akane(Rubiaceae), Cissampelos pareira and Abuta concolor (Menispermaceae), Nardostachys chinensis (Valerianacese), Mansoa alliaceae (Bignoniaceae), Casearia sylvestris (Flacourtiacear), Maytenus ilicifolia (Celastraceae), Hedychium coronarium (Zingiberaceae), Croton palanostigma(Euphorbiaceae), Cocculus trilobus(Menispermaceae), Ginkgo biloba(Ginkgoaceae), Alpinia galanga and Cucculus zanthorrhiza(Zingiberaceae), Evodia rutaecarpa(Rutaceae), and Periploca sepium(Asclepiadaceae) showed significant activity and their active principles were clarified. In this paper, a few antitumor substances in above plants are introduced.

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Trichodermamide A and Aspergillazine A, Two Cytotoxic Modified Dipeptides from a Marine-Derived Fungus Spicaria elegans

  • Liu Rui;Gu Qian-Qun;Zhu Wei-Ming;Cui Cheng-Bin;Fan Guo-Tao
    • Archives of Pharmacal Research
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    • 제28권9호
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    • pp.1042-1046
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    • 2005
  • Two known modified dipeptides, trichodermamide A (1) and aspergillazine A (2), were isolated from an ethyl acetate extract of the metabolite of a marine-derived fungus Spicaria elegans, and were found to have a weak cytotoxic effect on three cancer cell lines P388, A-549, and HL-60 agreed. To our knowledge, this is the first report on the isolation of compounds 1 and 2 from the fungus Spicaria elegans and their cytotoxic effect.

장성탄광 석탄과 수입 중국 석탄의 지구화학적 및 물리적 특성 (Geochemical and Physical Properties of the Jangseong and Imported Chinese Coals)

  • 전효택;김명균
    • 자원환경지질
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    • 제28권4호
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    • pp.381-388
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    • 1995
  • The petrographic, geochemical, and physical properties of the Jangseong and Chinese coals were investigated. The most common mineral matters of Jangseong coal are kaolinite, muscovite, sericite, illite, quartz and pyrophyllite. Mineral matters in Chinese coal are mainly composed of quartz, calcite, dolomite and kaolinite. Jangseong coal ash has higher content of $Al_2O_3$, $K_2O$, $TiO_2$, As, Rb and V, and lower content of CaO, MgO, $Na_2O$, $Fe_2O_3$ and $P_2O_5$ than those of Chinese coal ash. The liquid limit and the plasticity index of Jangseong coal were compared with those of Chinese coal. The result shows that the briquetting ability of Jangseong coal is a little bit better than that of Chinese coal. The briquetting ability is found to be principally dependent on the type and the content of mineral matter in coal, especially clay mineral.

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Aloe vera가 항암제의 세포독성에 미치는 영향 (Effects of Aloe vera on the Cytotoxicity of Anticancer Drugs in Vitro)

  • 표명윤;윤지현
    • 약학회지
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    • 제43권1호
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    • pp.104-110
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    • 1999
  • We investigated effects of methanol extract of Aloe vera on anticancer drugs(cisplatin, mitomycin C, 5-fluorouracil)-induced growth inhibition in p388, L1210, HCT-15, SK-HepG-1 as cancer cell lines and mouse splenocytes as a normal cell by MTT assay, respectively. We also examined the effects of aloe extract and mitomycin C on the mitogen(Con, A, LPS)-induced splenocyte proliferation. Aloe extract(0.25 mg/m , 1.25 mg/m , 2.5 mg/m , 5.0 mg/m ) showed dose-dependently selective cytotoxicity against the cancer cell lines. In contrast, Aloe extract increased the growth and proliferation of the normal mouse splenocytes. The combination of aloe extract with anticancer drugs showed an additive effect for the cytotoxicity against cancer cell lines. However, that combination reduced clealy the anticancer drugs-induced toxicity against the normal mouse splenocytes.

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초산균체 추출물의 In Vitro계 암세포 증식 억제 효과 (Cytotoxic Effect of the Extract from Acetobacter aceti OLS-001)

  • 이병우;유익제;유무영;황우익;최춘언
    • 한국식품과학회지
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    • 제27권4호
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    • pp.445-448
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    • 1995
  • Acetobacter aceti OLS-001 균체에서 추출한 추출물의 농도가 높을수록, 배양시간이 길수록 암세포의 증식 억제 효과가 높게 나타났으며, 현미경 관찰에서 본래의 암세포 형태가 변형되고 세포막사이의 경계막이 흐트러지면서 사멸하는 현상을 나타냈다.

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