• Health Policy and Management
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• v.24 no.2
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• pp.164-171
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• 2014

Background: Safety of drugs has become a major issue in public healthcare. Spontaneous reporting of adverse drug reaction (ADR) is the cornerstone in management of drug safety. We aimed to investigate the awareness and knowledge of spontaneous ADR reporting in general public of Korea. Methods: A total of 1,500 study subjects aged 19-69 years were interviewed with a questionnaire for their awareness and knowledge related to spontaneous ADR reporting. Computer assisted telephone interview was performed from 27th February 2013 to 4th March 2013. Target population was selected with quota sampling, using age, sex, and residence area. Healthcare professionals such as physicians, pharmacists, and nurses were excluded. The survey questions included awareness of spontaneous ADR reporting, opinions on ways to activate ADR reporting, and sociodemographic characteristics. Results: Overall awareness of spontaneous ADR reporting system was 8.3% (${\pm}2.53%$) among general population of Korea. Major source from which people got the information regarding ADR reporting was television/radio (69.9%), followed by internet (19.3%), and poster/brochure (6.1%). Awareness level differed between age groups (p<0.0001) and education levels (p<0.0001). Upon learning about the ADR reporting system, 88.5% of study subjects agreed on the necessity of ADR reporting system, while 46.6% thought promotion through internet and mass media as an effective way to activate ADR reporting. Conclusion: The overall awareness of spontaneous ADR reporting should be enhanced in order to establish a firm national system for drug safety. Adequate promotions should be performed targeting lower awareness groups, as well as various publicity activities via effective channels for the general population.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.5
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• pp.1508-1521
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• 2015

Vibrio harveyi is a pathogenic marine bacterium causing systemic symptoms resulting in mass mortalities in fishes and shrimps in aquaculture. Outer membrane proteins(OMPs) are related to the pathogenicity and thus good targets for diagnosis and vaccination for Gram negative bacteria. Recently vaccination strategies using the OMPs have been suggested to control vibriosis in several fish species. In this study, we have isolated V. harveyi from diseased marine fishes from different regions of Korea and investigated genetic variations of four OMP genes including OmpK, OmpU, OmpV and OmpW. Consequently, OmpK and U genes could be divided into 3 subgroups of type I, II, III and type A, B, C, respectively, without any correlation with geographical regions and species while OmpV and W were highly homologous. OmpW gene of V. harveyi FP4138 was fully sequenced and predicted the deduced amino acid sequence to form ${\beta}-barrel$ with hydrophobic channel. Indeed, the immunogenicity of recombinant OmpW produced in Escherichia coli was assessed by vaccinating flounder. As a result, the high antibody response with antibody titer of $4.2{\pm}0.7$ and protection with relative percent survival of 60% against artificial infection of V. harveyi were demonstrated. This result indicates that OmpW is a virulence related factor and it can be a vaccine candidate to prevent a high mortality caused by V. harveyi infection in olive flounder, Paralichthys olivaceus.

• Research in Community and Public Health Nursing
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• v.19 no.3
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• pp.431-442
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• 2008

Purpose: The Purpose of this study was to examine the degree of obesity stress and analyze factors having an effect on obesity stress among college women. Method: The subjects were 347 female students from a university in J City. Data were collected using a self-report questionnaire for general characteristics, health-related characteristics, and current and preferred somatotype. Obesity stress was measured using 10 items developed by Cho (1996) based on Body Attitudes questionnaire (BAQ) of Ben-Tovim and Walker (1991). The survey was conducted from September 4 to September 7, 2007. Data were analyzed by t-test, ANOVA, Scheffe test, Spearman's rank correlation test, and stepwise multiple regression using SPSS 14.0. Results: The average score of obesity stress was $2.78{\pm}0.90$ out of 5.00. Stepwise multiple regression analysis showed that the major factors that affect obesity stress of female college students were perceived body shape, disagreement between current and preferred somatotype, history of weight control, body mass index (BMI), and perceived health status, and these factors explained 38.4% of obesity stress. Conclusion: Subjective judgment in the perception of or preference for body shape was the most important factor affecting obesity stress in female college students. Therefore, a plan is necessary to mitigate obesity stress and evaluate individually subjects who perceive themselves to be fat or want to be thinner than the current somatotype. And consultation and constant management are needed to help the high risk group (experience of weight control, BMI ${\geq}23kg/m^2$, not good health status).

• Archives of Craniofacial Surgery
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• v.14 no.2
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• pp.102-106
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• 2013

Background: When using the anterior approach for performing superficial parotidectomy, the first thing to do is to find the buccal branch of the facial nerve and the parotid duct. The buccal branch usually runs transversely with the parotid duct from the anterior border of the parotid gland. We wanted to check the relationship between the two structures during the operation and to get clinically helpful information. Methods: Twelve patients with parotid mass were treated with superficial parotidectomy between May 2012 and August 2012. The outline of superficial and deep lobes of the parotid gland, parotid duct, and the buccal branch of the facial nerve were drawn on the transparent film by tracing the structures intraoperatively. Results: In 7 (58.3%) of 12 cases, the buccal branch of the facial nerve was located more caudally than the parotid duct at the anterior border of the superficial lobe of the parotid gland. In 3 cases (25%), the buccal branch was located more cephalically than the parotid duct. The mean distance between two structures were $2.54{\pm}1.48$ mm. In 11 cases, the parotid duct was located deeper than the buccal branch. Conclusion: The buccal branch of the facial nerve tends to be located more caudally than parotid duct and runs more superficially than parotid duct in all cases. We identified the relationship between the parotid duct and the buccal branch of the facial nerve during the operations on living subjects, not from the cadavers, so it would be a clinically helpful study which supplied more accurate anatomical information.

• Journal of Technologic Dentistry
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• v.35 no.3
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• pp.221-229
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• 2013

Purpose: The purpose of this study was to investigate the image and the awareness of dental laboratory technicians in health allied college students. Methods: The subject of this research are 431 health-related major students who are selected by convenience sampling from Seoul, Gyeonggi-do, Chungcheong-do, Jeolla-do and Gyeongsang-do. After a survey was conducted, the answer sheets from 401 respondents were analyzed except for 30 incomplete ones. The collected data is statistically analyzed by SPSS(Statistical Packages for Social Science 12.0. SPSS Inc., Chicago, IL, USA). Results: The findings of the study were as follows: As a result of general awareness about dental laboratory technicians, the health allied college students knew 83.0% about dental laboratory technician as a job. Respondents showed high recognition about dental laboratory technician as a job($3.62{\pm}0.31$), which showed that the health allied college students took a favorable view of dental laboratory in general. There were significant difference in dental laboratory technician image with age, gender(P<.05). Conclusion: It is required to develop programs such as proactive public relations or campaign via mass media that could enhance the public recognition about dental laboratory technician up to one of professional as required. It is also necessary that dental laboratory technicians make steady efforts for self-development to enhance their own job philosophy and skills in the level of quality, while they need various educations for building up their own favorable personality and positive ideas.

• Archives of Reconstructive Microsurgery
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• v.10 no.2
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• pp.93-98
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• 2001

Purpose : This describes our experience with a tenocutaneous free flap from the dorsum of the foot or radial forearm to reconstruct the dorsal skin and extensor tendons of the hand. Material and Methods : Between february 1987 and July 1998, we treated 9 patients with composite tissue loss on the dorsal hand caused by crushing injury. Nine men had an average age of 26.4 years(range, $19{\sim}47$). We treated 5 patients with the free dorsalis pedis flap including the extensor tendons and the superficial peroneal nerve and 4 patients with reverse forearm flap including the brachioradialis tendon and/or superficial radial nerve. Flap size was average 4.4(3,2cm. Evaluation of the results was based on the survived flap rate, the recovery rates for range of motion of the metacarpophalageal joints in the operated fingers. two-point discrimination. Results : All flaps were well vascularized and survived completely. Recovery rates for range of motion of the metacarpophalageal joints in operated fingers range from $78%{\sim}99%$(average, 90%). Two-point discrimination of the transferred flaps in 5 patients average $20{\pm}3.5mm$. Conclusion : The advantages of this procedure are mass action reconstruction with tendon, one-stage operation, faster healing with less adhesion formation, and early mobilization.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.47 no.3
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• pp.214-221
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• 2011

This study was performed to develop a video based system which can be used to measure the averaged fish size in a non-intrusive fashion. The design was based on principles of simple stereo geometry, incorporated fish dimensions weight relationships and took into consideration fish movement to lower system costs. As the fish size is an important factor that impacts the economy of an aquaculture enterprise. Size measurements, including fork length, width or height, girth, thickness and mass, can be used to determine fish condition in the fish farm, so the averaged fish size of fish cage needs to consistently monitor in open ocean aquaculture cage. A precision of ${\pm}3%$ for replicate length measurements of a 60cm bar is obtained at distances between 2.0 and 6.0m, and the mean fork length and mean swimming speed of bluefin tuna were estimated to 48.8cm and 0.78FL/s, respectively.

• Journal of the Korean Vacuum Society
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• v.6 no.4
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• pp.308-313
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• 1997

TDS (Thermal Lkso~ption Spectroscopy)system, for diagnosis of CRT manufacturing process, was designed and constructed. Outgassings and themla1 desorptions from the part or materials of CRT can be measured and analysed with this system at various temperatures. The system is consisted of 3 pirrts. vacuum chamher and pumping system with variable conductance, sample heating stages & their controller, and outgassing measurement devices, like as ion gauge or quadrupole mass spectrometer. The ultimate pressure of the system was under $1\times10^{-7}$ Pa. With the variable conductance system, the effective pumping speed of the chamber could he controlled from sub 11s to 100 11s. The effective pumping speed values were determined by dynamic flow measurement principle. The temperatures and ramp rate of sample were controlled by tungsten heater and PID controller up to $600^{\circ}C$ within t $\pm 1^{\circ}C$$difference to setting value. Ion gauge & QMS were calibrated for quantitative measurements. Some examples of TDS measurement data ;ind application on the CRT process analysis were shown.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7381-7383
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• 2013

Background: Male breast cancer accounts for less than 1% of all cancer in men and only around 1% of all diagnosed breast cancer. Despite a significant raise in the last 25 years, it still remains a rare disease. Materials and Methods: We conducted a retrospective study from 2004-2011 with 21 male breast cancer patients. We aimed to analyze the epidemiologic data (age, personal and family history), tumor characteristics (size, histological type, location, TNM stage, receptors), surgery, adjuvant chemotherapy and radiation therapy, hormonal therapy and survival (relapse, follow up, death) who reffered to our center with breast cancer. Results: The median age was $49.2{\pm}14.2$ years (range 30-83 years). A family history of breast cancer was noted in four cases. The main clinical complaint was a retroareolar mass in 85.7%of patients (n=18). Histologically, 85.7% (n=18)were invasive ductal carcinoma and 4.7% (n=1) had ductal carcinoma in situ and 9.4% (n=2) had mixed histology including invasive medullary and ductal carcinoma. Hormonal therapy was delivered to 16 cases (76.1%) due to ER or PR positivity. During median follow up of 30 months (3-84 month), distant metastases were evident in 4 cases (19%). During the follow-up period, only one patient died due to metastatic disease. The mean time to recurrence detection was 30 months. Conclusions: The percentage of cases of male breast cancer is very low compared to breast cancer in females, explaining why very few investigations have been conducted in Iran. Limited coverage in the literature make gender-specific findings difficult so future research of this entity involving multi-institutional cooperation and longer follow up is essential to provide new insights about the biological and clinical factors of this rare cancer.

• Clinical and Experimental Pediatrics
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• v.55 no.2
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• pp.54-57
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• 2012

Purpose: Somatic growth is an important indicator of health in children. Adequate organ growth is essential in growth and directly related to body growth. We consider renal length as a surrogate of organ growth in growing children. Measurement of weight, height, and many anthropometric indices, such as body surface area (BSA), body mass index (BMI), and Rohrer and Kaup indices, are used to evaluate growth status. The aim of this study was to evaluate the association between renal length and somatic parameters and analyze the affecting factors for renal size during growth. Methods: The data for renal length in 66 children (age, $12.9{\pm}15.6$ months; male/female, 34/32) were obtained. Each kidney was measured with ultrasonography and dimercaptosuccinic acid scan. The data on age, sex, height, and weight were obtained from the medical records. BSA, BMI, and Rohrer and Kaup indices were calculated from measured height and weight. BSA was calculated by 2 methods, and is expressed as BSA I and BSA II. Results: There were significant correlations between renal size and age, weight, height, BSA I, BSA II, and Rohrer index. In the regression analysis, the most significant contributing factor to renal growth was height ($R^2$=0.636, $P$ <0.001). Conclusion: Height seems to be the most important factor associated with organ growth in growing children. Further studies to evaluate adequate organ growth should be carried out.