• The Journal of Korean Society for Radiation Therapy
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• v.33
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• pp.89-97
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• 2021

Purpose: The purpose of this study is to compare and evaluate the dose change according to the gas volume variations in the rectum, which was not included in the treatment plan during radiation therapy for cervical cancer. Materials and methods: Static Intensity Modulated Radiation Therapy (S-IMRT) using a 9-field and Volumetric Modulated Arc Therapy (VMAT) using 2 full-arcs were established with treatment planning system on Computed Tomography images of a human phantom. Random gas parameters were included in the Planning Target Volume(PTV) with a maximum change of 2.0 cm in increments of 0.5 cm. Then, the Conformity Index (CI), Homogeneity Index (HI) and PTV D_max for the target volume were calculated, and the minimum dose (D_min), mean dose (D_mean) and Maximum Dose (D_max) were calculated and compared for OAR(organs at risk). For statistical analysis, T-test was performed to obtain a p-value, where the significance level was set to 0.05. Result: The HI coefficients of determination(R²) of S-IMRT and VMAT were 0.9423 and 0.8223, respectively, indicating a relatively clear correlation, and PTV D_max was found to increase up to 2.8% as the volume of a given gas parameter increased. In case of OAR evaluation, the dose in the bladder did not change with gas volume while a significant dose difference of more than D_mean 700 cGy was confirmed in rectum using both treatment plans at gas volumes of 1.0 cm or more. In all values except for D_mean of bladder, p-value was less than 0.05, confirming a statistically significant difference. Conclusion: In the case of gas generation not considered in the reference treatment plan, as the amount of gas increased, the dose difference at PTV and the dose delivered to the rectum increased. Therefore, during radiation therapy, it is necessary to make efforts to minimize the dose transmission error caused by a large amount of gas volumes in the rectum. Further studies will be necessary to evaluate dose transmission by not only varying the gas volume but also where the gas was located in the treatment field.

• Biomolecules & Therapeutics
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• v.6 no.3
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• pp.289-295
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• 1998

The bioequivalence of two nilvadipine products was evaluated in 16 normal male volunteers (age 22-32 yr, body weight 57-80 kg) following sidle oral dose. Test product was Overca $l_{R}$ tablet (Choong-Wae Pharm. Corp., Korea) and reference product was Nivadi $l_{R}$ tablet (Hyundai Pharm. Corp., Korea). Both products contain 4 mg of nilvadipine. One tablet of the test or the reference product was administered to the volunteers, respectively, by randomized two period cross-over study (2$\times$2 Latin square method). The determination of nilvadipine was accomplished using a validated capillary column GC with electron-capture detection. As a result of the assay validation, the quantiflcation of nilvadipine in human plasma by this technique was possible down to 0.5 ng/ml using 1 ml of plasma. Absolute overall recovery from five replicate analyses of nilvadipine-spiked sample were 88.4$\pm$ 10.24% (mean$\pm$ 5.D.) for human plasma of 10 ng/ml. The coefficients of variation (C.V.) were less than 20% and the actual concentration of nilvadipine measured by GC ranged from 80 to 99% in all plasma. Average drug concentrations at each sampling time and pharmacokinetic parameters calculated were not significantly different between two products (p>0.05); the area under the curve from time zero to 8 hr (AUCo-$_{8 hr}$) (22.8$\pm$5.90 vs 22.2$\pm$6.10 ng . hr/ml), maximum plasma concentration ( $C_{max}$) (10.0$\pm$2.85 vs 9.3$\pm$3.28 ng/ml) and time to reach maximum plasma concentration ( $T_{max}$) (1.2$\pm$0.31 vs 1.3 $\pm$0.47 hr). The differences of mean AU $Co_{8hr}$ $C_{max}$, and $T_{max}$ between the two products (2.25, 7.65, and 10.30%, respectively) were less than 20%. The power (1-$\beta$) and treaeent difference (7) for AU $Co_{8hr}$, and $C_{max}$ were more than 0.8 and less than 0.2, respectively. Although the power for Tmax was under 0.8, Tm\ulcorner of the two products was not significantly different from each other (p>0. 05). These results suggest that the bioavailability of Overeat tablet is not significantly different from that of Nivadil tablet. Therefore, two products are bioequivalent based on the current results.sults.lts.lts.lts.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.31 no.6_2
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• pp.521-527
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• 2013

Rule set is an important step which impacts significantly on accuracy of object-oriented classification result. Therefore, this paper proposes a rule set to extract land cover from Landsat Thematic Mapper (TM) imagery acquired in Donganh, Hanoi, Vietnam. The rules were generated to distinguish five classes, namely river, pond, residential areas, vegetation and paddy. These classes were classified not only based on spectral characteristics of features, but also indices of water, soil, vegetation, and urban. The study selected five indices, including largest difference index max.diff; length/width; hue, saturation and intensity (HSI); normalized difference vegetation index (NDVI) and ratio vegetation index (RVI) based on membership functions of objects. Overall accuracy of classification result is 0.84% as the rule set is used in classification process.

• Journal of IKEEE
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• v.18 no.4
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• pp.502-508
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• 2014

This paper has reviewed the performances of various AGCs which can be adopted in IEEE802.11p modems. IEEE802.11p, a high speed mobile communication standard for vehicles, requires high performance signal detector since the channel impulse responses are varied rapidly in time. In order to select the optimal signal detector, we simulated the performances of three detection methods. One is using RSSI signal, the other is using RSSI signal and I/Q signal, and the third is using I/Q signal through the Monte Carlo simulation. We evaluated the performances of the algorithms using our own system based on MAX 2829 transceiver(MAXIM $Integrated^{TM}$) in a real vehicular environment. As a result, the experiment using Fully I/Q signal derives the most excellent performance with the lowest minimum receiver sensitivity, packet error rate (PER) and false alarm rate (FAR).

• Proceedings of the Korea Information Processing Society Conference
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• 2000.10a
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• pp.849-852
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• 2000

본 논문에서는 RSA 암호 시스템의 Montgomery 모듈러 곱셈 알고리듬을 개선한 고속 모듈러 곱셈 알고리듬을 제안하고, Hybrid 구조의 가산기를 사용한 고속 모듈러 곱셈 알고리듬의 설계에 관하여 기술한다. 기존 Montgomery 알고리듬에서는 부분합계산시 2번의 덧셈연산이 요구되지만 제안된 방법에서는 단지 1번의 덧셈 연산으로 부분 합을 계산할 수 있다. 또한 덧셈 연산 속도를 향상시키기 위하여 Hybrid 구조의 가산기를 제안한다. Hybrid 가산기는 기존의 CLA(Carry Look-ahad Adder)와 CSA(Carry Select Adder)알고리듬을 혼합한 구조를 기본으로 하고 있다. 제안된 고속 모듈러 곰셈기는 VHDL(VHSIC Hardware Description Language)을 이용하여 모델링하였고, $Synopsys^{TM}$사의 Design Analyzer를 이용하여 논리합성(Altera 10K lib. 이용)을 수행하였다. 성능 분석을 위하여 Altera MAX+ PLUS II 상에서 타이밍 시뮬레이션을 수행하였고, 실험을 통하여 제안한 방법의 효율성을 입증하였다.

• Proceedings of the IEEK Conference
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• 2002.06a
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• pp.81-84
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• 2002

The WRR scheduling algorithm is widely used in ATM networks due to its simplicity and the low cost of hardware implementation. It guarantees minimum cell rate according to the weight of each queue. The fairness is a important factor for ABR service. That is, Scheduling algorithm allocates network resources fairly to each VC. In this paper, we propose a scheduling algorithm for satisfying the two fairness criteria, MCR plus equal share and Maximum of MCR or Max-Min share, among the six criteria defined by ATM Forum TM 4.1 specification. The WRR, Nabeshima et al, and the proposed scheduling algorithms are compared with respect to fairness and convergence time throughout experimental simulation.

• The Journal of Advanced Prosthodontics
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• v.3 no.3
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• pp.126-131
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• 2011

PURPOSE. The aim of this in vitro study was to examine the curing efficiency of various resin-based materials polymerized through ceramic restorations with 3 different thicknesses. Curing efficiency was evaluated by determining the surface microhardness (VHN) of the resin specimens. MATERIALS AND METHODS. Four kinds of resin materials were used. Z350 (3M ESPE $Filtek^{TM}$ Z350: A2 Shade), Z250 (3M ESPE $Filtek^{TM}$ Z250: A2 Shade) and $Variolink^{(R)}$ II (VL: Ivoclar vivadent, base: transparent) either with or without a self-curing catalyst (VLC: Ivoclar vivadent, catalyst: low viscosity/transparent) were filled into the silicone mold (10 mm diameter, 1 mm thick). They were cured through ceramic discs (IPS e.max Press MO-0 ingot ivoclar vivadent, 10 mm diameter, 0.5, 1 and 2 mm thicknesses) by LED light-curing units for 20 and 40 seconds. Vicker's microhardness numbers (VHNs) were measured on the bottom surfaces by a microhardness tester. Data were analyzed using a 3-way analysis of variance (ANOVA) at a significance level of 0.05. RESULTS. The thickness of ceramic disc increased, the VHNs of all four resin types were decreased (P<.05). The mean VHN values of the resins light cured for 40 seconds were significantly higher than that of LED for 20 seconds in all four resin materials (P<.05). VLC showed significantly higher VHN values than VL regardless of other conditions (P<.05). Z350 and Z250 showed higher values than VL or VLC (P<.01). CONCLUSION. Thinner ceramic disc with increased curing time resulted higher VHN values of all resin materials. The use of a catalyst produced a greater hardness with all polymerization methods. Restorative resin materials (Z350, Z250) showed higher VHN values than resin cement materials (VL, VLC).

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.306-306
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• 2011

대상유역의 합리적인 홍수량 산정을 위해서는 풍부한 홍수자료를 바탕으로 직접적인 빈도해석을 적용하는 것이 가장 적정한 방법으로 알려져 있다. 하지만 국내의 대부분 유역은 관측된 홍수 자료가 제한적이고, 미계측 유역이므로 빈도해석을 통한 홍수량의 산정은 현실적으로 불가능한 실정이다. 이에 국내에서는 홍수량 산정에 대한 대안으로 강우-유출관계의 선형성을 가정한 집중형 강우-유출모형을 적용하고 있다. 하지만 집중형 강우-유출모형은 경험적인 공식에 의해 결정되는 수문매개변수의 비합리성 및 유역분할, 유역 하도추적의 구축방식에 따라 상이한 홍수량이 산정되는 문제점이 지적되고 있다. 따라서 최근에는 경험적이고 개념적인 집중형 유출모형을 지양하고, 격자체계를 기반으로 하고 있는 분포형 강우-유출모형의 연구가 활발히 진행되고 있는 상황이다. 본 연구의 목적은 남강 유역에서의 분포형 강우-유출모형 적용성 검증에 있다. 따라서 남강 유역 내에 발생한 4개의 호우사상을 선정한 후 강우 레이더 영상인 CAPPI영상 및 C-Max영상을 이용하여 면적강우량을 산정하였다. C-Max 영상을 이용하여 산정된 면적강우량은 지점강우를 이용한 면적강우량과 비교해 130%이상 과대 산정되는 경향을 나타낸 반면, CAPPI 영상을 이용하여 산정된 면적강우량은 10%이하의 오차를 나타내었다. 따라서 본 연구에서는 CAPPI 영상을 분포형 유출 모형인 VfloTM에 입력하여 유출을 모의 하였다. 모의된 유출곡선과 관측된 유출곡선을 비교 검토한 결과 80%이상의 높은 상관성을 나타낸 반면 첨두유출량 오차는 30%이상의 오차를 나타내었다. 하지만 강우보정기법인 G/R보정 기법을 적용한 후에는 첨두유출량 오차가 10%미만으로 감소하는 것으로 나타났다. 따라서 남강 유역에 분포형 유출모형을 적용하기 위해서는 다양한 강우 사상에 대한 지속적인 연구가 수행되어야 할 것으로 판단된다.

• Journal of Radiation Protection and Research
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• v.34 no.2
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• pp.43-48
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• 2009

When the PDD (percentage depth dose) in the megavoltage beams is measured in the water phantom, the polarity and ion recombination effects of ionization chambers with depth in water are not usually taken into consideration. We try to investigate if those variations with depth should be taken into consideration or could be ignored for the thimble type semiflex ionization chamber (PTW $31010^{TM}$, SN 1551). According to the recommendation of IAEA TRS-398, the 4 representative depths of $d_s$, $d_{max}$, $d_{90}$ and $d_{50}$ were used for the electron beams. For the photon beams, the 4 depths were arbitrarily chosen for the photon beams, which were $d_s$, $d_{max}$, $d_{10}$ and $d_{20}$. For the high energy photon beam both polarity and ion recombination factors of the chamber with depth in water gives the good agreements within the maximum $\pm$0.2%, while the $C_{polS}$ with depth came within the maximum $\pm$ 0.4% and the $C_{IRS}$ within the maximum $\pm$0.6% in every electron beam used. This study shows that PDI (percentage depth ionization) could be a good approximation to PDD for the chamber used.

• Journal of radiological science and technology
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• v.41 no.6
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• pp.553-560
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• 2018

PET-CT and PET-MRI which integrates CT using ionized radiation and MRI using phenomena of magnetic resonance are determined to have the limitation to apply the semi-quantitative index, standardized uptake value (SUV), with the same level due to the fundamental differences of image capturing principle and reorganization, hence, their correlations were analyzed to provide their clinical information. To 30 study subjects maintaining pre-treatment, $^{18}F-FDG$ (5.18 MBq/㎏) was injected and they were scanned continuously without delaying time using $Biograph^{TM}$ mMR 3T (Siemens, Munich) and Biograph mCT 64 (Siemens, Germany), which is an integral type, under the optimized condition except the structural differences of both scanners. Upon the measurement results of $SUV_{max}$ setting volume region of interest with evenly distributed radioactive pharmaceuticals by captured images, $SUV_{max}$ mean values of PET-CT and PET-MRI were $2.94{\pm}0.55$ and $2.45{\pm}0.52$, respectively, and the value of PET-MRI was measured lower by $-20.85{\pm}7.26%$ than that of PET-CT. Also, there was a statistically significant difference in SUVs between two scanners (P<0.001), hence, SUV of PET-CT and PET-MRI cannot express the clinical meanings in the same level. Therefore, in case of the patients who undergo cross follow-up tests with PET-CT and PET-MRI, diagnostic information should be analyzed considering the conditions of SUV differences in both scanners.