• Biotechnology and Bioprocess Engineering:BBE
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• 제10권4호
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• pp.357-361
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• 2005

The bioconversion of linoleic acid (LA) to conjugated linoleic acid (CLA) was investigated to examine LA-adaptation of Bifidobacterium breve KCTC 3461 to additions of 1 to 5 mg/mL of LA overtime. To induce LA-adaptation, B. breve KCTC 3461 was treated with LA, according to three schemes. For LA-adapted B. breve the maximum concentration of CLA, $300\~350{\mu}g/mL$, was obtained in cys-MRS medium containing 1 mg/mL of LA. The CLA production significantly increased with increasing LA concentration, from 1 to 4 mg/mL, but the conversion of LA to CLA gradually decreased. The CLA production capability of B. breve, and its tolerance, improved significantly with LA-adaptation. The addition of LA (1 mg/mL) into the culture broth after 24 h of cultivation in a 100-mL media bottle was most effective at promoting CLA production. In a 2.5-L stirred-tank bioreactor, the observed conversion and productivity of $56.6\%\;and\;35.4{\mu}gmL^{-1}h^{-1}$, respectively, by LA-adapted B. breve were approximately 6.6 and 9.8 times higher than those of LA-unadapted B. breve.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 Techno-Fair 및 추계학술대회 논문집 전기물성,응용부문
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• pp.192-193
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• 2007

A hollow cathode which has extremely stable discharge characteristic has been developed. This is composed of the two separated lanthanum hexaboride ($LaB_6$) of a disk type in the tube as the electron emitters. The way of design is of great advantage to extend the surface discharge area of the $LaB_6$, which is also useful for optimal fixing of the $LaB_6$. The hollow cathode is capable of producing 30 kW (100 V, 300 A) of power continuously.

• 전기학회논문지
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• 제57권1호
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• pp.78-81
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• 2008

A hollow cathode which has extremely stable discharge characteristic has been developed. This is composed of the two separated lanthanum hexaboride(LaB6) of a disk type in the tube as the electron emitters. The way of design is of great advantage to extend the surface discharge area of the LaB6, which is also useful for optimal fixing of the LaB6. The hollow cathode is capable of producing 30 kW(100 V, 300 A) of power continuously. Because the generated plasma beam with the high temperature(above $3000^{\circ}C$) from the hollow cathode passes through the center hole of the two intermediate electrodes, it is designed with the high temperature material of the tungsten and the suitable structure of the water cooling. The combinations of the hollow cathode and the two intermediate electrodes are practically useful for the ion plating plasma beam source.

• 한국임상수의학회지
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• 제39권6호
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• pp.287-293
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• 2022

Radiographic left atrial dimension (RLAD) is a useful measurement to assess left atrial enlargement in dogs. There are studies on the use of RLAD on various breeds of dogs, but no study on a specific breed with myxomatous mitral valve disease (MMVD). This study was conducted to compare RLAD measurements in Maltese dogs with MMVD ACVIM stage B1 and B2, and also to investigate the correlation of RLAD with the LA:Ao ratio. A total of 29 Maltese dogs were the subjects of this study. Each dog was diagnosed with MMVD ACVIM stage B1 or B2 based on physical examination, thoracic radiography, and echocardiography. The vertebral heart size (VHS), RLAD, LVIDDn, and LA:Ao ratio were measured and compared to evaluate the differences. There were significant differences in the RLAD, LVIDDn, and LA:Ao ratio between dogs with MMVD ACVIM stage B1 and those with stage B2. There was a significant correlation between the LA:Ao ratio and both the RLAD and VHS measurements, but the correlation coefficient was higher for RLAD. The RLAD scores exhibited a significant difference between dogs with ACVIM Stage B1 and with those with B2, and these scores had a higher correlation with the LA:Ao ratio measured by echocardiography than with VHS.

• 한국자기학회지
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• 제3권1호
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• pp.1-6
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• 1993

희토류-전이금속 화합물, $LaCo_{13}$에 대한 자체충족적 국제밀도함수근사 LMTO (Linearized Muffin-Tin Orbital) 에너지 띠 전자구조 계산을 토대로 하여 이물질의 상자성, 강자성상에서 자성을 포함한 전기적, 자기적 물성을 고찰하였다. 강자성상에서의 CoI, CoII원자들의 자기모멘트는 각각 $1.34,\;1.65{\mu}_{B}$로 계산되었으며 이는 Co 원자당 평균 자기모멘트 $1.60{\mu}_{B}$에 해당하여 실험치 $1.56~1.68{\mu}_{B}$와 근사한 결과를 얻었다.

• Bulletin of the Korean Chemical Society
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• 제9권6호
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• pp.345-349
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• 1988

The polycrystalline powder of (CaLa) (MgMo)$O_6$ has been prepared at $1350^{\circ}C$ in $H_2/H_2O$ and $N_2$ flowing atmosphere. The powder X-ray diffraction pattern indicates that (CaLa) (MgMo)$O_6$ has a monoclinic perovskite structure with the lattice constants $a_0=b_0=7.901(1){\AA}$, $c =7.875(1){\AA}\;and\;{\gamma}=89^{\circ}$16'(1'), which can be reduced to orthorhombic unit cell, a = 5.551(1) ${\AA}$, b = 5.622(1) ${\AA}$ and c = 7.875(1) ${\AA}$. The infrared spectrum shows two strong absorption bands with their maxima at 590($ν_3$) and 380($ν_4$) cm, which are attributed to $2T_{1u}$ modes indicating the existence of highly charged molybdenum octahedron $MoO_6$ in the crystal lattice. According to the magnetic susceptibility measurement, the compound follows the Curie-Weiss law below room temperature with the effective magnetic moment 1.83(1)$_{{\mu}B}$, which is well consistent with that of spin only value (1.73 $_{\mu}_B$) for $Mo^{5+}$ with $4d^1$-electronic configuration within the limit of experimental error. From the thermogravimetric analysis, it has been confirmed that (CaLa) (MgMo)$O_6$ decomposes gradually into $CaMoO_4,\;MoO_3,\;MgO,\;La_2O_3$ and unidentified phases due to the oxidation of $Mo^{5+}$ to $Mo^{6+}$.

• 한국세라믹학회지
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• 제31권6호
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• pp.617-622
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• 1994

Single crystals of misfit layered (LaS)xVS2(x 1.18) were grown using LaCl3(or I2) as a mineralizer (or transport agent) for the single crystal X-ray diffraction analysis. Procession photographs of (LaS)xVS2(x 1.18) were analyzed as the stacking structure of two kinds of LaS-and VS2-subcell. The result shows that two sublattices have common periodicities along the a*-and c*-axes, respectively, but not along the b*-axis. Sublattice dimensions of LaS and VS2 layers along b-axis were 5.67$\AA$ and 3.42$\AA$, respectively. Their ratio was 1.657 which is very close to 5/3.

• 치위생과학회지
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• 제2권1호
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• pp.15-19
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• 2002

고삼 추출물의 암세포에 대한 세포독성을 파악하기 위하여 고삼의 에틸 아세테이트 소분획으로 MTT 정량분석을 실시하였다. 고삼의 에틸 아세테이트 소분획은 암세포인 KB 세포, B16 세포, HeLa 세포와 MCF-7 세포에 대하여 $6.25{\mu}g/ml$ 농도부터 세포독성이 나타났으며, 12.5, 25, 50 및 $100{\mu}g/ml$까지 각각의 농도별로 세포독성은 증가하였고, 통계적으로 유의성이 인정되었다(p<0.05). KB 세포에 대한 $IC_{50}$는 $56.58{\mu}g/ml$, B16 세포에 대한 $IC_{50}$는 $65.43{\mu}g/ml$, HeLa 세포에 대한 $IC_{50}$는 $83.95{\mu}g/ml$, MCF-7 세포에 대한 $IC_{50}$는 $106.65{\mu}g/ml$로 나타났다. 고삼의 에틸 아세테이트 소분획은 암세포의 성장을 억제하였고, 세포독성의 강도는 B16 세포, HeLa세포, MCF-7 세포, KB 세포 순서로 높게 나타났다.

• Journal of Nutrition and Health
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• 제24권4호
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• pp.314-325
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• 1991

식이지방의 수준에 따라 n6 와 n3 불포화지방산이 혈장 지질조성에 미치는 영향과 또 그 기전이 다른지를 연구하고자 Sprague Dawley 종 수컷쥐에게 저지방(LF, 10% Cal)식이와 고지방식이(HF, 40% Cal)를 각각 6주동안 투여하였으며, 사용된 기름은 포화지방산 급원으로는 쇠기름, n6 linoleic acid(LA) 급원으로 corn oil, n3 ${\alpha}-linolenic$ acid(LL) 급원으로 perilla oil, n3 eicosapentaenoic acid(EPA)와 docosahexaenoic acid(DHA) 급원으로 fish oil이었다. Ultracentrifugation 방법으로 VLDL fraction을 분리하여 thin layer chromatography에 의해서 화학적조성을 구하였다. Plasma cholestere 수준은 LF 와 HF 모두 n6 LA에 의해서는 오히려 증가되었고 n3 LL과 n3 EPA에 의해서는 감소되었으며, HF 에서 n3 EPA가 가장 cholesterol 저하효과가 있었다. HDL-Chol 농도는 n6 LA에 의해서 증가되었으나, HF 경우 n3 EPA에 의해서 유의성있게 감소되었다. Plasma TG 농도는 n3 EPA에 의해서 가장 감소되었고 간의 lipogenic enzyme 활성을 억제하였으며 VLDL fraction의 TG상대적양(%)이 유의성 있게 낮아졌다. 이때 LF 군에서는VLDL fraction의 apo-B의 상대적양(%)이 감소되지 않았으나 HF군에서 n3 EPA에 의해서 유의성 있게 낮았다. 그러므로 n3 EPA의 hvpotriglyceridemic effect는 간에서 lipogenesis를 억제하여 plasma VLDL로 TG 분비가 억제되었을 것이며, HF일 경우는 간에서 apo-B 생성도 억제되었다. 관상동맥성심장질환의 예방적 차원에서 평상시에도 쇠기름과 corn oil 보다는 n3 PUFA가 풍부한 들기름이나 생선을 더욱 이용하는 것이 바람직하다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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• pp.323-323
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• 2007

Influence of $La_2O_3$ addition to $CaO-B_2O_3$-based glass on the water leaching resistance of the glass was first investigated. The optimized $La_2O_3-CaO-B_2O_3$(LCB) glass was ball milled for varying time, followed by mixing with $Al_2O_3$ crystalline phase to form $Al_2O_3$-LCB glass composites at $875^{\circ}C$ for 1h. Microwave dielectric properties of the composites were investigated as a function of the ball milling time of the LCB glass. Dielectric constant and quality factor of the composites were 6.31 and 13856 GHz, respectively, when the LCB glass was ball milled for 2h prior to mixing with $Al_2O_3$.