• Proceedings of the IEEK Conference
• /
• 2000.11a
• /
• pp.337-340
• /
• 2000

In this paper, I compared some characteristics between HPA and LPA using Feedforward method. Feedforward method is known for best IMD correction. HPA generated 46.5㏈c at 45.5㏈m output power. But, using feedforward linearing method, I could improve IMD to 67.17㏈c at the same output power. IMD could be improved 20.67㏈ at 45.5㏈m output power. I measured average power, IMD, total current, and efficiency of two amplifier at many different power levels. I could get about 70d3c IMD using feedforward method.

• 한국노년학
• /
• v.37 no.2
• /
• pp.349-368
• /
• 2017

The purpose of this study is to empirically structure the patterns of baby boomer retirees'consumption and their effects on depression in later life. Using the 5th wave of Korea Retirement and Income Study(KReIS) in 2013, of baby boomers born in 1955 to 1963, we analyzed those who were completely retired(n=420). The Latent Profile Analysis(LPA) classified the empirical patterns of consumption and then a multiple regression analyzed the effect of consumption patterns on depression among these baby boomer retirees. The LPA results showed that the consumption patterns consist of five groups: (1) Basic life-oriented class(26.9%), (2) Balanced consumption class(29.3%), (3) Social life-oriented class(18.3%), (4) Leisure-oriented class(18.5%), and (5) Education-oriented class(7.0%). Baby boomer retirees' depression was associated with their consumption patterns. Specifically, the basic life-oriented class showed significantly lower depression than the education-oriented class. Other correlates such as higher education, having no spouse, lower subjective health, greater limitations in physical functions, having a diagnosed disability, having fewer children, higher dissatisfaction with leisure activities, and lower self-perceived economic status were associated with higher levels of depression in this study. These findings suggest meaningful implications for gerontological policy and practice for baby boomer retirees in Korea. In light of vulnerable retirement preparation, social services specialized for baby boomers should consider financial education for revamping consumption scale beyond asset management and long-term case management of pre and post retirement cases.

• The Journal of the Korea Contents Association
• /
• v.20 no.9
• /
• pp.365-379
• /
• 2020

The purpose of this study identifies the patterns of students' learning motivation profiles on entrepreneurial educational motivation among a sample of university students from one of the Korean national university(n=614). This study also examines the relationship between students' learning motivation profiles and entrepreneurial intention and types of entrepreneurship. In order to explore the types of leaning motivation profiles, a latent profile analysis was employed. Result from LPA revealed five distinct types of learning motivation profiles fit the data best, and these five profiles are compared with students' entrepreneurial intentions and types of entrepreneurship. Results showed that Profiles (profile 5 and 4-high goal orientation) are associated with the higher level of entrepreneurial intention. Regarding the type of entrepreneurship, the majority of all students are interested in individual and co-entrepreneurship with friend regardless of the patterns of profiles.

• Journal of Biomedical Engineering Research
• /
• v.28 no.3
• /
• pp.429-440
• /
• 2007

A coded excitation has been studied to improve the performance for ultrasound imaging in term of SNR, imaging frame rate, contrast to tissue ratio, and so forth. However, it requires a complicated arbitrary waveform transmitter for each active channel that is typically composed of a multi-bit Digital-to-Analog Converter (DAC) and a linear power amplifier (LPA). Not only does the LPA increase the cost and size of a transmitter block, but it consumes much power, increasing the system complexity further and causing a heating-up problem. This paper proposes an optimized 1.5bit fourth order sigma-delta modulation technique applicable to design an efficient arbitrary waveform generator with greatly reduced power dissipation and hardware. The proposed SDM can provide a required SQNR with a low over-sampling ratio of 4. To this end, the loop coefficients are optimized to minimize the quantization noise power in signal band while maintaining system stability. In addition, the decision level for the 1.5 bit quantizer is optimized for a given input waveform, which results in the SQNR improvement of more than 5dB. Computer simulation results show that the SQNR of a FM(frequency modulated) signal generated by using the proposed method is about 26dB, and the peak side-lobe level (PSL) of its compressed waveform on receive is -48dB.

• Journal of Yeungnam Medical Science
• /
• v.41 no.2
• /
• pp.113-119
• /
• 2024

Background: Missing isoniazid (INH) resistance during tuberculosis (TB) diagnosis can worsen the outcomes of INH-resistant TB. The BD MAX MDR-TB assay (BD MAX) facilitates the rapid detection of TB and INH and rifampin (RIF) resistance; however, data related to its performance in clinical setting remain limited. Moreover, its effect on treatment outcomes has not yet been studied. Methods: We compared the performance of BD MAX for the detection of INH/RIF resistances to that of the line probe assay (LPA) in patients with pulmonary TB (PTB), using the results of a phenotypic drug sensitivity test as a reference standard. The treatment outcomes of patients who used BD MAX were compared with those of patients who did not. Results: Of the 83 patients included in the study, the BD MAX was used for an initial PTB diagnosis in 39 patients. The sensitivity of BD MAX for detecting PTB was 79.5%. The sensitivity and specificity of BD MAX for INH resistance were both 100%, whereas these were 50.0% and 95.8%, respectively, for RIF resistance. The sensitivity and specificity of BD MAX were comparable to those of LPA. The BD MAX group had a shorter time interval from specimen request to the initiation of anti-TB drugs (2.0 days vs. 5.5 days, p=0.001). Conclusion: BD MAX showed comparable performance to conventional tests for detecting PTB and INH/RIF resistances. The implementation of BD MAX as a diagnostic tool for PTB resulted in a shorter turnaround time for the initiation of PTB treatment.

• Journal of Chest Surgery
• /
• v.21 no.6
• /
• pp.957-969
• /
• 1988

There is tendency of increasing number and decreasing age of patients who are indicated for Rastelli operation for their cyanotic congenita heart disease. So there is the need to find the creiterion which saves the patients from early postoperative hemodynamic disturbances. We reviewed the 26 patients who had been performed Rastelli operation at Seoul national University hOipital from January 1981 to June 1988. mean age of the patients was 7.8 $\pm$ 3.4 years (range 2.5-1.5 years), mean body surface area(BSA) 0.79 $\pm$ 0.25 $m^{2}$(range 0.49-1.51 $m^{2}$) and mean hematocrit 57.95 $\pm$ 12%(range 48-80%). We diveded these patients into survived group and died group before postoperative 72 hours, and analysed preoperative arterial oxygen saturation($SaO_{2}$), the ratio of diameter of fight pulmonary artery to ascending aorta(RA:/AA), the ratio of both right and left pulmonary artery diameter to descending thoracic aorta(RPA+LPA/DTA), pulmonary artery index(PA index), cardiopulmonary bypass time, aorta cross-clamping time, postoperative perfusion state and total amount of dopamine infused postoperatively. The results showed that RPA+LPA/DTA and PA index were statistically significatn factors to influence early postoperative cardiac death rate (P<0.05). Especially there were good linear correlations between PA index(X) and perpheral perfusion index(Y)(Y = -1.15 + 0.02 X, r = 0.86, P<0.01) and between PA index(X) and total amount of dopamine infused before postoperative 72 hours(mg/kg, Y)(Y = 61.94 - 0.15 X, r = - 0.80, P<0.01). Also there were tendencies that the higher RPA + LPA/DTA(Y), the betterperipheral perfusion (X) and the lower need of dopamine(X), but no statistical significance. (Y = 0.78 + 1.60 X, r = 0.49, P>0.05) And the discrimant analysis showed that patients with PA index over 221 $mm^{2}$/BSA could undergo correction with 25 per cent of error rate. In conclusion, early postoperative hemodynamic states could be predicted by preoperatively measured PA index, and which can be used as a criterion for Rastelli operation performed on cyanotic congenital heart disease.

• Korean Journal of School Psychology
• /
• v.11 no.1
• /
• pp.253-274
• /
• 2014

The present study classified groups based on latent profile of self-determination motivation(amotivation, external motivation, intrinsic motivation), and examined the determinants for each group. The data was collected through panel data of Korea Education Longitudinal Study(KELS), total 5,459 participants who answered questionnaires of self-determination motivation of two times both second grade of middle school and second grade of high school. To identify the change motivational type, standardized residual was conducted using SPSS 17.0., and the latent classes for the change of motivational type was investigated using M-Plus in the frame work of Latent Profile Analysis(LPA). The results indicated that five groups(increase of self-determination, self-determination maintenance, self-determination developmental delay, elf-determination confusion, decrease of self-determination group) were classified based on latent profile. In addition, parental control, academic self-concept, teacher-student relationship, test anxiety, avoidance orientation, gender, father's education, and income were significantly related to each group. Lastly, the implications for directions of the adolescent counseling, limitations and future research are discussed.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.11 no.7
• /
• pp.1289-1295
• /
• 2007

In this paper, we implemented high-performance concurrent control system which manages whole RF systems with digital type and communicates with remote station on both wire and wireless networking. It consists of FPGA (Field Programmable Gate Array) part which controls forward/reverse LPA (Linear Power Amplifier), forward/reverse LNA (Low Noise Amplifier), channel cut wire/wireless TCP/IP, etc, master microprocessor (AVR), which manages the whole control system, Slave microprocessor which communicates SA (Spectrum Analyzer) and observes frequency spectrum of each channel with the resolution of 5KHz, 10 channel card microprocessor which independently observes each channel card and sets frequency synthesizer in channel cut and other peripherals and logics. The whole system is divided to two parts of H/W (hardware) and S/W (software) considering operational efficiency and concurrency, and implementation and cost. H/W consists of FPGA and microprocessor. We expected the optimized operation through H/W and SW co-design and hybrid H/W architecture.

• Journal of Ginseng Research
• /
• v.43 no.2
• /
• pp.305-311
• /
• 2019

Background: Gintonin is a ginseng-derived exogenous ligand of the G protein-coupled lysophosphatidic acid (LPA) receptor. We previously reported that gintonin stimulates gliotransmitter release in primary cortical astrocytes. Astrocytes play key roles in the functions of neurovascular systems. Although vascular endothelial growth factor (VEGF) is known to influence the normal growth and maintenance of cranial blood vessels and the nervous system, there is little information about the effect of gintonin on VEGF regulation in primary astrocytes, under normal and hypoxic conditions. Methods: Using primary cortical astrocytes of mice, the effects of gintonin on the release, expression, and distribution of VEGF were examined. We further investigated whether the gintonin-mediated VEGF release protects astrocytes from hypoxia. Results: Gintonin administration stimulated the release and expression of VEGF from astrocytes in a concentration- and time-dependent manner. The gintonin-mediated increase in the release of VEGF was inhibited by the LPA1/3 receptor antagonist, Ki16425; phospholipase C inhibitor, U73122; inositol 1,4,5- triphosphate receptor antagonist, 2-APB; and intracellular $Ca^{2+}$ chelator, BAPTA. Hypoxia further stimulated astrocytic VEGF release. Gintonin treatment stimulated additional VEGF release and restored cell viability that had decreased due to hypoxia, via the VEGF receptor pathway. Altogether, the regulation of VEGF release and expression and astrocytic protection mediated by gintonin under hypoxia are achieved via the LPA receptor-VEGF signaling pathways. Conclusion: The present study shows that the gintonin-mediated regulation of VEGF in cortical astrocytes might be neuroprotective against hypoxic insults and could explain the molecular basis of the beneficial effects of ginseng on the central nervous system.

• Journal of Ginseng Research
• /
• v.44 no.1
• /
• pp.67-78
• /
• 2020

Background: Gintonin (GT), a novel ginseng-derived exogenous ligand of lysophosphatidic acid (LPA) receptors, has been shown to induce cell proliferation and migration in the hippocampus, regulate calcium-dependent ion channels in the astrocytes, and reduce β-amyloid plaque in the brain. However, whether GT influences autophagy in cortical astrocytes is not yet investigated. Methods: We examined the effect of GT on autophagy in primary cortical astrocytes using immunoblot and immunocytochemistry assays. Suppression of specific proteins was performed via siRNA. LC3 puncta was determined using confocal microscopy. Results: GT strongly upregulated autophagy marker LC3 by a concentration- as well as time-dependent manner via G protein-coupled LPA receptors. GT-induced autophagy was further confirmed by the formation of LC3 puncta. Interestingly, on pretreatment with an mammalian target of rapamycin (mTOR) inhibitor, rapamycin, GT further enhanced LC3-II and LC3 puncta expression. However, GT-induced autophagy was significantly attenuated by inhibition of autophagy by 3-methyladenine and knockdown Beclin-1, Atg5, and Atg7 gene expression. Importantly, when pretreated with a lysosomotropic agent, E-64d/peps A or bafilomycin A1, GT significantly increased the levels of LC3-II along with the formation of LC3 puncta. In addition, GT treatment enhanced autophagic flux, which led to an increase in lysosome-associated membrane protein 1 and degradation of ubiquitinated p62/SQSTM1. Conclusion: GT induces autophagy via mTOR-mediated pathway and elevates autophagic flux. This study demonstrates that GT can be used as an autophagy-inducing agent in cortical astrocytes.