• 한국유기농업학회지
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• 제27권3호
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• pp.247-269
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• 2019

Although food related lifestyle has been widely discussed over the last ten years, the majority of research on food related lifestyle has been only conducted in terms of a variable-centered approach. But, recently there is a growing body of research on food related lifestyle profiles over the last three years from the view of a person-centered approach. This study conducted both a cluster analysis and a latent profile analysis (LPA) to identify the patterns of potential food related lifestyle customer profiles based on the five components on the sample of customer, who bought organic products (n=509). The results of each statistical analysis showed both quantitatively and qualitatively different types of food related lifestyle customer profiles even though there were similar types of profiles identified in common between these two analyses. These various profiles were then compared with customer's level of buying behaviors (e.g., buying attitude and buying intentions). Results showed that food related lifestyle profiles with respect to the high level of interesting in dietary life in terms of health and safety are associated with the higher level of buying behaviors. Based on the results, implications for food related lifestyle literature, practices and future research are discussed.

• 수산해양기술연구
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• 제16권2호
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• pp.69-76
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• 1980

This paper describes the measurement of the underwater noises produced by the engine vibration around the engine room of stern trawler MIS Sae-Ba-Da(2275GT, 3,600 PS) and pole kner M/S Kwan-Ak-San (243 GT, 1000 PS) while the ship is stopping. The underwater noise pressure level was measured with the underwater level meter of which measuring range is 100 to 200 dB(re bLPa). A and B denotes the maximum pressure level measured at right beneath the bottom of the engine room, while the main engine of the Sae-Ba-Da revoluted at 750 and 500 rpm, respectively. C denotes that of the main engine of the Kwan-Ak-San revoluted at 350 rpm, and D that of the generator of the Sae-Ba-Da revoluted at 720 rpm. Thus A, B, C and D were set for the standard sound source for the experiment. The results obtained are as follows: 1. The noise Pressure level at A, B, C and D were 170.5,165,153 and 158dB, respectively. 2. When the check points distanted vertically 1, 10, 20, 30, 40, 50m from the sound source, the underwater noise presure levels were 170.5, 155, 148, 144 and 138 dB and the directional angle was 116\ulcorner in case of A. 3. The sound level attenuated at the rate of 20dB per 10" meters of the horizontal distance from the sound sources. 4. The frequency distribution of the noise was 100Hz to 10KHz and predominant frequency was 700 to 800Hzminant frequency was 700 to 800Hz

• Genomics & Informatics
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• 제9권4호
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• pp.152-160
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• 2011

Hypertension is the major factor of most death and high blood pressure (BP) can lead to stroke, myocardial infarction and cardiac failure. Moreover, hypertension is strongly correlated with body mass index (BMI). Although the exact causes of hypertension are still unclear, some of genetic loci were discovered from genome-wide association study (GWAS). Therefore, it is essential to study genetic variation for finding more genetic factor affecting hypertension. The purpose of our study is to conduct a CNV association study for hypertension-related traits, BP and BMI, in Korean individuals. We identified 2,206 CNV regions from 3,274 community-based Korean participants using the Affymetrix Genome-Wide Human SNP Array 6.0 platform and performed a logistic regression analysis of CNVs with two hypertension-related traits, BP and BMI. Moreover, the 4,692 participants in an independent cohort were selected for respective replication analyses. GWAS of CNV identified two loci encompassing previously known hypertension-related genes: LPA (lipoprotein) on 6q26, and JAK2 (Janus kinase 2) on 9p24, with suggestive p-values (0.0334 for LPA and 0.0305 for JAK2 ). These two positive findings, however, were not evaluated in the replication stage. Our result confirmed the conclusion of CNV study from the WTCCC suggesting weak association with common diseases. This is the first study of CNV association study with BP and BMI in Korean population and it provides a state of CNV association study with common human diseases using SNP array.

• 한국산학기술학회논문지
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• 제22권6호
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• pp.550-557
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• 2021

본 연구에서는 한부모가 된 후의 변화 및 어려움에 기초한 차별적인 특징을 보이는 잠재집단을 탐색하고, 확인된 잠재집단에 한부모의 배경 변인이 영향을 미치는지, 그리고 확인된 잠재집단에 따라 한부모의 우울 수준에 차이가 있는지 살펴보았다. 이를 위해 2018 전국 한부모 가족 실태조사 자료의 2,500명을 분석 대상으로 하였으며, 잠재프로파일 분석 방법을 사용하였다. 분석 결과, 첫째, 8개 항목에 대한 한부모가 된 후의 변화 및 어려움에 기초한 잠재집단은 '양육 안정 집단', '보통 집단', '경제적 안정 집단', '잠재적 위험군 집단'의 4개 잠재집단이 존재하는 것으로 확인되었다. 그리고 한부모의 배경변인 중 학력보다는 성별과 경제적 측면의 정부지원유형 및 취업 여부가 잠재집단 분류에 영향을 미치는 것으로 확인되었다. 특히, 여성 한부모, 미취업, 저소득지원가구 일 때 잠재적 위험군에 속할 가능성이 높은 것으로 나타났다. 잠재집단에 따라 한부모의 우울 수준에 차이가 있는 것으로 나타났으며, 잠재적 위험군 집단이 양육 안정 집단, 보통 집단, 경제적 안정 집단보다 우울 수준이 높은 것으로 확인되었다. 본 연구는 한부모가 된 후 한부모가 겪는 변화 및 어려움의 모습은 다를 수 있으며, 각 잠재집단의 특성을 고려한 사회적 지원이 제공될 때 한부모지원정책의 실효성을 높일 수 있음을 시사한다.

• 문화기술의 융합
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• 제9권6호
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• pp.899-910
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• 2023

전 세계를 비롯해 우리나라에서도 시니어세대는 지속적으로 증가하고 있으며, 여가활동에 대한 희망도 동시에 증가하여 지속적으로 관광을 희망하고 있는 것으로 나타나고 있다. 시니어세대는 관광 산업이 지속적으로 성장할 수 있는 원동력의 역할을 담당할 것이다. 본 연구는 시니어세대의 라이프스타일에 따른 관광 태도 및 관광 행동의향을 파악하기 위해 사람중심접근법(person-centered approach)을 토대로 잠재프로파일분석(LPA)을 실행하여 시니어세대의 라이프스타일 프로파일 유형을 탐색하고, 라이프스타일 프로파일 유형별 관광 태도 및 관광 행동의향의 차이점이 있는지를 실증 분석하였다. 시니어세대의 라이프스타일은 안전추구, 문화활동추구, 지식추구, 건강추구, 사회활동추구의 5개 요인으로 분류되었고, 안전추구를 비롯한 모든 요인에서 다른 프로파일들에 비해 높은 값을 나타낸 프로파일 3 집단에서 관광태도와 관광행동의향이 가장 높은 것으로 나타났다. 본 연구는 시니어세대의 관광행동 차이의 관계적 특성을 다면적으로 파악하였고, 관광업계에서 중요하게 세분시장으로 형성되고 있는 시니어세대의 이해를 통해 관광소비행동 마케팅 전략 수립에 유용한 시사점을 제공하였다는 점에서 의의가 있다.

• 한국임상약학회지
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• 제3권2호
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• pp.125-130
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• 1993

The particle size distribution and physical stability of commercial lipid emulsion inject, $intralipos^R$ before and after mixture with total parenteral nutrition(TPN) was tested. Three TNAs were prepared by adding intralipos to P-TPN, Neo-TPN and IVH-2 respectively. Particle size of fat emulsion in three TNA preparations were measured by using LPA-3000 photon correlater. Each TNAs was stored for 48 hours at $4^{\circ}C\;and\;25^{\circ}C.$ During storage, three TNAs showed the particle size in the range of 40-1000nm(about $100\%$ of total fat) and in the range of 1000-8000nm(less than $0.005\%$ of total fat). All TNAs were stable in terms of pH and visual appearance. The results showed that added lipid emulsion was stable for 48 hours at $4^{\circ}C\;and\;25^{\circ}C$.

• Journal of Chest Surgery
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• 제21권1호
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• pp.10-16
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• 1988

Ten patients with tetralogy of Fallot were studied angiocardiographically before a modified Blalock-Taussig shunt and again 25*3.2 months after the previous shunt. All of ten patients had patent previous shunt at the time of follow up examination. Pre-and postoperative diameters of left and right pulmonary artery and descending aorta were measured and pulmonary artery index [the sum of the crossectional areas of the right and left pulmonary arteries standardized by the body surface area] was calculated. The ratio of mean diameter of left and right pulmonary arteries to the diameter of the descending aorta [LPA+RPA/2xDA] was increased postoperatively by 0.20*0.068 [p=0.020]. Mean PAI [pulmonary artery index] increased from 283.8*178.4 mm/m2 BSA to 345.8~144.5 mm/m2 BSA after shunt operation [p=0.019]. This results suggested that the modified Blalock-Taussig shunt was effective to help growth of the pulmonary arteries in most cases of the study populations but the ones with the PAI>233mm*/m* BSA appeared less benefited by Blalock Taussig shunt. Calculation of PAI could be an aid to making a decision whether to perform a one stage corrective surgical procedure or a palliative shunt procedure in the patient with small pulmonary arteries.

• Asian Pacific Journal of Cancer Prevention
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• 제16권4호
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• pp.1443-1448
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• 2015

To investigate the significance of FOXO3a and Ki67 in human lung adenocarcinomas. Envision immunohistochemical staining and Western blotting were used to examine the protein expression of FOXO3a in 127 cases of human lung adenocarcinoma specimens. The positive rate in lung adenocarcinoma (55.9%) was lower than that in normal tissues (80%). We found that the expression of FOXO3a was closely related with the degree of differentiation, TNM staging, lymph node metastasis and survival. In addition, significant differences in the different pathological types of lung adenocarcinoma cases (P<0.01). The FOXO3a positive rate of the acini as the main type (APA) (86.7%) and the lepidic as the main type (LPA) (82.4%) was higher than the solid as the main type (SPA) (50.0%), the papilla as the main type (PPA) (42.9%) and the micropapilla as the main type (MPA) (9.4%). Moreover, the expression of FOXO3a was negatively related with Ki67 expression. Our results suggested that the expression of FOXO3a is closely correlated with the aggressiveness of lung adenocarcinoma. It was indicated that disregulation of FOXO3a might play key roles in the occurrence and development of lung a denocarcinoma and joint detection of the two markers might play an important role in diagnosing tumors.

• 생명과학회지
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• 제21권6호
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• pp.767-774
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• 2011

세포의 이동은 많은 생리적 반응뿐만 아니라 암 세포 침윤과 전이에 중요한 역할을 수행한다. 본 연구에서는 마늘이 암세포의 이동에 미치는 영향을 확인하기 위해, 표준 마늘과 흑마늘을 준비하고 이들을 각각 물을 이용하여 추출하거나 건조하여 추출한 추출물 4 종류를 이용하여 항침윤성과 항전이성에 대해 조사하였다. 실험결과, 암세포의 이동은 건조 후 헥산으로 추출한 분획에 암세포의 이동 억제 활성이 관찰되었다. 이 분획을 박막 크로마토그래피를 이용하여 분리정제하였으며, 이를 inhibitor of cancer metastasis from garlic #27 (ICMG-27)이라 명명하였다. ICMG-27 (6 ${\mu}g/ml$)을 세포에 처리하였을 때, IGF-1에 의한 OVCAR-3와 NIH-3T3 세포의 이동을 억제함을 확인하였다. 그러나 ICMG-27은 mouse embryonic fibroblast (MEF) 세포에서 IGF-1에 의한 이동에는 영향을 주지 않았다. 이러한 ICMG-27은 OVCA-3, SKOV-3와 MDA-MB-231 세포와 같은 암세포에서 모두 IGF-1에 의한 이동을 억제함을 관찰하였다. 마지막으로 세포이동을 일으키는 인자에 따른 ICMG-27의 영향을 확인한 것으로, IGF-1, lysophosphatidic acid (LPA), sphingosine-1-phosphate (S1P), leukotriene B4 (LTB4) 그리고, angiotensinII (AngII)에 의한 OVCAR-3 세포의 이동을 모두 억제하였다. 이러한 결과를 바탕으로, ICMG-27은 암세포의 이동을 유도하는 많은 인자들에 의한 필수적인 단계를 차단함으로써, 암세포의 이동을 억제하는 것을 확인 할 수 있었으며, ICMG-27에 의한 암세포의 항 침윤 메커니즘의 규명은 암환자의 치료에 기초적인 발판을 제공할 것입니다.

• 한국산업보건학회지
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• 제31권3호
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• pp.237-254
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• 2021

Objectives: This study aims to classify the latent profiles in the exposure to hazard factors of salaried employees and test the determinants. Methods: Latent profile analysis(LPA) was conducted using data from the fifth Korean Working Conditions Survey(KWCS). 30,050 of salaried employees were the subjects of this study. After classifying the employees, multinomial logistic regression was used to test the determinants. Results: Salaried employees were classified with three latent profiles based on the exposure to the hazard factors. Employees included in class 1(32.8%) tend to experience low level of physical hazard factors, moderate level of psychological hazard factors, and high level of office work hazard factors. Employees included in class 2(61.8%) tend to be exposed to the moderate to high level of physical hazard factors, moderate to low level of psychological hazard factors, and low level of office work hazard factors. Employees included in class 3(5.4%) tend to experience high level of psychological and physical hazard factors, and moderate level of office work hazard factors. After classification, the demographic, health-, and employment-related variables were tested. Conclusions: This study clarified the features of each class, and proved that employees in class 3 are quite hazardous in that they are exposed to physical and psychological hazard factors much more frequently than other employees. Thus, this study can be used in predicting the high-risk employees and taking preemptive measures for preventing industrial accidents.