• Korean Journal of Organic Agriculture
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• v.27 no.3
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• pp.247-269
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• 2019

Although food related lifestyle has been widely discussed over the last ten years, the majority of research on food related lifestyle has been only conducted in terms of a variable-centered approach. But, recently there is a growing body of research on food related lifestyle profiles over the last three years from the view of a person-centered approach. This study conducted both a cluster analysis and a latent profile analysis (LPA) to identify the patterns of potential food related lifestyle customer profiles based on the five components on the sample of customer, who bought organic products (n=509). The results of each statistical analysis showed both quantitatively and qualitatively different types of food related lifestyle customer profiles even though there were similar types of profiles identified in common between these two analyses. These various profiles were then compared with customer's level of buying behaviors (e.g., buying attitude and buying intentions). Results showed that food related lifestyle profiles with respect to the high level of interesting in dietary life in terms of health and safety are associated with the higher level of buying behaviors. Based on the results, implications for food related lifestyle literature, practices and future research are discussed.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.16 no.2
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• pp.69-76
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• 1980

This paper describes the measurement of the underwater noises produced by the engine vibration around the engine room of stern trawler MIS Sae-Ba-Da(2275GT, 3,600 PS) and pole kner M/S Kwan-Ak-San (243 GT, 1000 PS) while the ship is stopping. The underwater noise pressure level was measured with the underwater level meter of which measuring range is 100 to 200 dB(re bLPa). A and B denotes the maximum pressure level measured at right beneath the bottom of the engine room, while the main engine of the Sae-Ba-Da revoluted at 750 and 500 rpm, respectively. C denotes that of the main engine of the Kwan-Ak-San revoluted at 350 rpm, and D that of the generator of the Sae-Ba-Da revoluted at 720 rpm. Thus A, B, C and D were set for the standard sound source for the experiment. The results obtained are as follows: 1. The noise Pressure level at A, B, C and D were 170.5,165,153 and 158dB, respectively. 2. When the check points distanted vertically 1, 10, 20, 30, 40, 50m from the sound source, the underwater noise presure levels were 170.5, 155, 148, 144 and 138 dB and the directional angle was 116\ulcorner in case of A. 3. The sound level attenuated at the rate of 20dB per 10" meters of the horizontal distance from the sound sources. 4. The frequency distribution of the noise was 100Hz to 10KHz and predominant frequency was 700 to 800Hzminant frequency was 700 to 800Hz

• Genomics & Informatics
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• v.9 no.4
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• pp.152-160
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• 2011

Hypertension is the major factor of most death and high blood pressure (BP) can lead to stroke, myocardial infarction and cardiac failure. Moreover, hypertension is strongly correlated with body mass index (BMI). Although the exact causes of hypertension are still unclear, some of genetic loci were discovered from genome-wide association study (GWAS). Therefore, it is essential to study genetic variation for finding more genetic factor affecting hypertension. The purpose of our study is to conduct a CNV association study for hypertension-related traits, BP and BMI, in Korean individuals. We identified 2,206 CNV regions from 3,274 community-based Korean participants using the Affymetrix Genome-Wide Human SNP Array 6.0 platform and performed a logistic regression analysis of CNVs with two hypertension-related traits, BP and BMI. Moreover, the 4,692 participants in an independent cohort were selected for respective replication analyses. GWAS of CNV identified two loci encompassing previously known hypertension-related genes: LPA (lipoprotein) on 6q26, and JAK2 (Janus kinase 2) on 9p24, with suggestive p-values (0.0334 for LPA and 0.0305 for JAK2 ). These two positive findings, however, were not evaluated in the replication stage. Our result confirmed the conclusion of CNV study from the WTCCC suggesting weak association with common diseases. This is the first study of CNV association study with BP and BMI in Korean population and it provides a state of CNV association study with common human diseases using SNP array.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.550-557
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• 2021

This study examined the latent groups regarding the changes and difficulties after becoming a single parent and analyzed the differences in the backgrounds and depressive levels according to each group. The data of 2,500 single parents from the 2018 Single Parent Family Survey were analyzed by Latent Profile Analysis (LPA). LPA indicated four-profile groups: 1) parenting stability group, 2) normal group, 3) economic stability group, and 4) potential-risk group. Its determinants included gender and economic status, including government funding type and employment status rather than academic status. Specifically, female single parents with an unemployed or low-income support household were more likely to be linked to the potential-risk group. In addition, the potential-risk group showed a higher depressive level than the parenting stability group, normal group, and economic stability group. The significance of this study is that distinguished intervention based on the characteristics of each group can promote the effectiveness of single-parent family support policy.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.899-910
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• 2023

The majority of research on lifestyle has been conducted based on a variable-centered approach. However, over the last decades, there is a growing body of research on lifestyle in terms of a person-centered approach. Hence, this study identifies senior generations' profiles based on the combination of the five realms of lifestyle. More specifically, this study utilized a Latent profile analysis(LPA) to explore both quantitatively and qualitatively distinct types of senior generation' lifestyle profiles. As a result, the five distinct types of senior lifestyle profiles were identified and these five profiles were then contrasted with traveling attitude and behavioral intention(traveling intention). In addition, this study attempted to identify similarity in the patterns of relations with theoretical antecedent, correlate and outcome variables. Results showed that even though senior generation belonging to profile groups pertaining to the high level of all five types of lifestyle were associated with a high level of attitude and behavior intention, there was no differences among the profiles. This means that regardless of the patterns of senor generation lifestyle profiles, there was no similarity. Nevertheless, it should be considered that senior generation consider a security when making a travel ling decision regardless of the patterns of lifestyle profiles. This results suggest that senior generation' traveling satisfaction is more likely obtained with the experience of safety and convenience during their travel. At last, this study discusses some implication tourism theory related to lifestyle, practices and future research on tourism profiles.

• Korean Journal of Clinical Pharmacy
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• v.3 no.2
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• pp.125-130
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• 1993

The particle size distribution and physical stability of commercial lipid emulsion inject, $intralipos^R$ before and after mixture with total parenteral nutrition(TPN) was tested. Three TNAs were prepared by adding intralipos to P-TPN, Neo-TPN and IVH-2 respectively. Particle size of fat emulsion in three TNA preparations were measured by using LPA-3000 photon correlater. Each TNAs was stored for 48 hours at $4^{\circ}C\;and\;25^{\circ}C.$ During storage, three TNAs showed the particle size in the range of 40-1000nm(about $100\%$ of total fat) and in the range of 1000-8000nm(less than $0.005\%$ of total fat). All TNAs were stable in terms of pH and visual appearance. The results showed that added lipid emulsion was stable for 48 hours at $4^{\circ}C\;and\;25^{\circ}C$.

• Journal of Chest Surgery
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• v.21 no.1
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• pp.10-16
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• 1988

Ten patients with tetralogy of Fallot were studied angiocardiographically before a modified Blalock-Taussig shunt and again 25*3.2 months after the previous shunt. All of ten patients had patent previous shunt at the time of follow up examination. Pre-and postoperative diameters of left and right pulmonary artery and descending aorta were measured and pulmonary artery index [the sum of the crossectional areas of the right and left pulmonary arteries standardized by the body surface area] was calculated. The ratio of mean diameter of left and right pulmonary arteries to the diameter of the descending aorta [LPA+RPA/2xDA] was increased postoperatively by 0.20*0.068 [p=0.020]. Mean PAI [pulmonary artery index] increased from 283.8*178.4 mm/m2 BSA to 345.8~144.5 mm/m2 BSA after shunt operation [p=0.019]. This results suggested that the modified Blalock-Taussig shunt was effective to help growth of the pulmonary arteries in most cases of the study populations but the ones with the PAI>233mm*/m* BSA appeared less benefited by Blalock Taussig shunt. Calculation of PAI could be an aid to making a decision whether to perform a one stage corrective surgical procedure or a palliative shunt procedure in the patient with small pulmonary arteries.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.4
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• pp.1443-1448
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• 2015

To investigate the significance of FOXO3a and Ki67 in human lung adenocarcinomas. Envision immunohistochemical staining and Western blotting were used to examine the protein expression of FOXO3a in 127 cases of human lung adenocarcinoma specimens. The positive rate in lung adenocarcinoma (55.9%) was lower than that in normal tissues (80%). We found that the expression of FOXO3a was closely related with the degree of differentiation, TNM staging, lymph node metastasis and survival. In addition, significant differences in the different pathological types of lung adenocarcinoma cases (P<0.01). The FOXO3a positive rate of the acini as the main type (APA) (86.7%) and the lepidic as the main type (LPA) (82.4%) was higher than the solid as the main type (SPA) (50.0%), the papilla as the main type (PPA) (42.9%) and the micropapilla as the main type (MPA) (9.4%). Moreover, the expression of FOXO3a was negatively related with Ki67 expression. Our results suggested that the expression of FOXO3a is closely correlated with the aggressiveness of lung adenocarcinoma. It was indicated that disregulation of FOXO3a might play key roles in the occurrence and development of lung a denocarcinoma and joint detection of the two markers might play an important role in diagnosing tumors.

• Journal of Life Science
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• v.21 no.6
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• pp.767-774
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• 2011

Cell migration plays a fundamental role in cancer cell invasion and metastasis as well as in many physiological responses. Here, we screened four different sources of garlic - water extract of normal and black garlic, as well as dried normal and black garlic - for the identification of anti-invasive and anti-metastatic activity on cancer cells. Inhibition of cancer cell migration was observed in the hexane extract of dried-garlic. Inhibitory activity was further purified to near homogeneity by thin layer chromatography and named $\b{i}$nhibitor of $\b{c}$ancer $\b{m}$etastasis from garlic #27 (ICMG-27). ICMG-27 completely blocked insulin-like growth factor-1 (IGF-1)-induced OVCAR-3 cell migration at 6 ${\mu}g/ml$. ICMG-27 completely blocked IGF-1-induced OVCAR-3 and NIH-3T3 cell migration whereas IGF-1-induced mouse embryonic fibroblast (MEF) cell migration was not affected byICMG-27. ICMG-27 inhibited all the tested IGF-1-induced cancer cell migration such as OVCAR-3, SKOV-3, and MDA-MB-231 cells. Finally, ICMG-27 could inhibit IGF-1-, lysophosphatidic acid (LPA)-, sphingosine-1-phosphate (S1P)-, leukotriene B4 (LTB4)-, and angiotensin II (AngII)-induced OVCAR-3 cell migration. These results indicate that ICMG-27 inhibits cancer cell migration by blocking essential steps in many agonists-induced cancer cell migrations. Unveiling an anti-invasive mechanism of ICMG-27 on cancer cells will provide a basis for cancer therapy.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.31 no.3
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• pp.237-254
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• 2021

Objectives: This study aims to classify the latent profiles in the exposure to hazard factors of salaried employees and test the determinants. Methods: Latent profile analysis(LPA) was conducted using data from the fifth Korean Working Conditions Survey(KWCS). 30,050 of salaried employees were the subjects of this study. After classifying the employees, multinomial logistic regression was used to test the determinants. Results: Salaried employees were classified with three latent profiles based on the exposure to the hazard factors. Employees included in class 1(32.8%) tend to experience low level of physical hazard factors, moderate level of psychological hazard factors, and high level of office work hazard factors. Employees included in class 2(61.8%) tend to be exposed to the moderate to high level of physical hazard factors, moderate to low level of psychological hazard factors, and low level of office work hazard factors. Employees included in class 3(5.4%) tend to experience high level of psychological and physical hazard factors, and moderate level of office work hazard factors. After classification, the demographic, health-, and employment-related variables were tested. Conclusions: This study clarified the features of each class, and proved that employees in class 3 are quite hazardous in that they are exposed to physical and psychological hazard factors much more frequently than other employees. Thus, this study can be used in predicting the high-risk employees and taking preemptive measures for preventing industrial accidents.