• 제목/요약/키워드: $K^{+}$ channels

검색결과 4,177건 처리시간 0.032초

인도네시아 중부 칼리만탄 뚬방라판 지역 금광상의 산상 (Occurrence of Gold Deposits of the Tumbang Lapan Area of the Middle Kalimantan, Indonesia)

  • 김인준
    • 자원환경지질
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    • 제38권3호
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    • pp.347-353
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    • 2005
  • 뚬방라판 지역의 지질은 페름기-석탄기의 변성암(천매암), 백악기의 화강암 및 석탄기에서 제 3기의 퇴적암과 화산암 등으로 구성되어있다. 조사지역에는 3조의 단층이 발달하며 열수용액의 통로역할을 하였으며, 이 단층을 따라서 열수용액이 주입되어 응회암내에 석영맥을 형성하였다. 열수에 의한 모암의 변질작용은 조사지역에서 주로 이질 변질작용과 프로필릭 변질작용이 우세하게 나타나며 일부 규화작용도 초래된다. 이질 변질작용은 고령토+견운모+석영+녹니석+황철석의 광물조합을 갖는다. 반면 프로필릭 변질작용은 녹니석+녹염석+장석+석영+황철석+자철석의 광물조합을 갖는다. 조사지역에는 맥상, 파쇄충진, 망상 등의 열수광상이 발달되어 있다 석영맥과 변질암 시료들의 분석결과 금이 0.01g/t에서 4.6g/t으로 나타났다.

유체역학적 집속 효과를 이용한 단일 박테리아 주화성의 정량적 분석 (Quantitative Analysis of Single Bacterial Chemotaxis Using a Hydrodynamic Focusing Channel)

  • 전호정;이용구;진송완;구상모;이창수;유정열
    • 대한기계학회논문집B
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    • 제31권3호
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    • pp.209-216
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    • 2007
  • Bacterial chemotaxis is essential to the study of structure and function of bacteria. Although many studies have accumulated the knowledge about chemotaxis in the past, the motion of a single bacterium has not been studied much yet. In this study, we have developed a device microfabricated by soft lithography and consisting of microfluidic channels. The microfluidic assay generates a concentration gradient of chemoattractant linearly in the main channel by only diffusion of the chemicals. Bacteria are injected into the main channel in a single row by hydrodynamic focusing technique. We measured the velocity of bacteria in response to a given concentration gradient of chemoattractant using the microfludic assay, optical systems with CCD camera and simple PTV (Particle Tracking Velocimetry) algorithm. The advantage of this assay and experiment is to measure the velocity of a single bacterium and to quantify the degree of chemotaxis by statistically analyzing the velocity at the same time. Specifically, we measured and analyzed the motility of Escherichia coli strain RP437 in response to various concentration gradients of L-aspartate statistically and quantitatively by using this microfluidic assay. We obtained the probability density of the velocity while RP437 cells are swimming and tumbling in the presence of the linear concentration gradient of L-aspartate, and quantified the degree of chemotaxis by analyzing the probability density.

수평 코류게이트 채널로 구성된 가정용 가습 소자 (Residential Humidifying Elements Comprizing Horizontal Corrugated Channels)

  • 김내현
    • 대한기계학회논문집B
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    • 제41권9호
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    • pp.579-586
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    • 2017
  • 본 연구에서는 절곡 방식의 일제 레이온/PE(90:10) 가정용 가습 소자를 대체할 수 있는 새로운 가습 원단과 형상에 대해 검토하였다. 레이온/PET(50:50), 크라프트/PET (40:60), 크라프트/PET/활성탄, 세 종류 원단으로 시료를 만들고 가습 성능 실험을 수행하였다. 가습 효율은 일본 제품을 100%로 볼 때 레이온/PET 소자는 대략 59%, 크라프트/PET 소자는 62%, 크라프트/PET/활성탄 소자는 84%로 나타났다. 이는 소자에 흡습성을 부여하는 레이온 또는 크라프트 섬유의 양이 일본 소자에 비하여 작기 때문이다. 한편 활성탄이 코팅된 경우는 가습 성능이 현저히 향상되었다. 반면 압력 손실은 일본 제품에 비해 개발품에서 현저히 작게 나타났다. 동일 소비 동력에서의 가습 성능을 의미하는 $j_m/f^{1/3}$의 값은 크라프트/PET/활성탄 소자에서 일본 소자보다 60%에서 82% 크게 나타났다. 실험 데이터를 이론 모델의 예측치와 비교하였다.

Overexpression in Arabidopsis of a Plasma Membrane-targeting Glutamate Receptor from Small Radish Increases Glutamate-mediated Ca2+ Influx and Delays Fungal Infection

  • Kang, Seock;Kim, Ho Bang;Lee, Hyoungseok;Choi, Jin Young;Heu, Sunggi;Oh, Chang Jae;Kwon, Soon Il;An, Chung Sun
    • Molecules and Cells
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    • 제21권3호
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    • pp.418-427
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    • 2006
  • Ionotropic glutamate receptors (iGluRs) are ligand-gated nonselective cation channels that mediate fast excitatory neurotransmission. Although homologues of the iGluRs have been identified in higher plants, their roles are largely unknown. In this work we isolated a full-length cDNA clone (RsGluR) encoding a putative glutamate receptor from small radish. An RsGluR:mGFP fusion protein was localized to the plasma membrane. In Arabidopsis thaliana overexpressing the fulllength cDNA, glutamate treatment triggered greater $Ca^{2+}$ influx in the root cells of transgenic seedlings than in those of the wild type. Transgenic plants exhibited multiple morphological changes such as necrosis at their tips and the margins of developing leaves, dwarf stature with multiple secondary inflorescences, and retarded growth, as previously observed in transgenic Arabidopsis overexpressing AtGluR3.2 [Kim et al. (2001)]. Microarray analysis showed that jasmonic acid (JA)-responsive genes including defensins and JA-biosynthetic genes were up-regulated. RsGluR overexpression also inhibited growth of a necrotic fungal pathogen Botrytis cinerea possibly due to up-regulation of the defensins. Based on these results, we suggest that RsGluR is a glutamate-gated $Ca^{2+}$ channel located in the plasma membrane of higher plants and plays a direct or indirect role in defense against pathogen infection by triggering JA biosynthesis.

Induction of Pacemaker Currents by DA-9701, a Prokinetic Agent, in Interstitial Cells of Cajal from Murine Small Intestine

  • Choi, Seok;Choi, Jeong June;Jun, Jae Yeoul;Koh, Jae Woong;Kim, Sang Hun;Kim, Dong Hee;Pyo, Myoung-Yun;Choi, Sangzin;Son, Jin Pub;Lee, Inki;Son, Miwon;Jin, Mirim
    • Molecules and Cells
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    • 제27권3호
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    • pp.307-312
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    • 2009
  • The interstitial cells of Cajal (ICC) are pacemaking cells required for gastrointestinal motility. The possibility of whether DA-9701, a novel prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber, modulates pacemaker activities in the ICC was tested using the whole cell patch clamp technique. DA-9701 produced membrane depolarization and increased tonic inward pacemaker currents in the voltage-clamp mode. The application of flufenamic acid, a non-selective cation channel blocker, but not niflumic acid, abolished the generation of pacemaker currents induced by DA-9701. Pretreatment with a $Ca^{2+}$-free solution and thapsigargin, a $Ca^{2+}$-ATPase inhibitor in the endoplasmic reticulum, abolished the generation of pacemaker currents. In addition, the tonic inward currents were inhibited by U-73122, an active phospholipase C inhibitor, but not by $GDP-{\beta}-S$, which permanently binds G-binding proteins. Furthermore, the protein kinase C inhibitors, chelerythrine and calphostin C, did not block the DA-9701-induced pacemaker currents. These results suggest that DA-9701 might affect gastrointestinal motility by the modulation of pacemaker activity in the ICC, and the activation is associated with the non-selective cationic channels via external $Ca^{2+}$ influx, phospholipase C activation, and $Ca^{2+}$ release from internal storage in a G protein-independent and protein kinase C-independent manner.

Media Education in Higher Learning Institutions in Korea: Changes and Realities Reflected in Curricula

  • Lee, Mina
    • 인터넷정보학회논문지
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    • 제19권2호
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    • pp.69-75
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    • 2018
  • Over the years, the types of media and media usage patterns have rapidly changed and communication channels in society have diversified. The courses in the universities on "media" have accordingly been altered to adapt to these changes. To investigate the ways in which the higher learning institutions in Korea have adapted to the changes in the media environment, this study analyzed the curriculum provided by the communication/media departments in the areas of Seoul and Gyeonggi-do. For the curricula analysis,names of the course soffered at the selected universitie swere analyzed; then keywords were extracted from morphological analysis of thes enames. Also, to investigate the changes over time, the courses offered in the years 2008 and 2017 were selected. The network analysis was done by using Netminer; the shape, main components, and major nodes of the network were compared. The results showed that firstly, overall shape of network from 2008 and 2017 looked similar. Due to the existence of concentrations within the major, the overall shape of the network showed several independent components, rather than one network. However, the analysis revealed differences in major nodes in the 2008 case from 2017. In the 2008 case, 'programming,' 'media,' 'introduction' among others were the major nodes; in 2017, 'editing' was the most important node. This signifies that in 2017, the curricula in the selected universities emphasized more practical and technical media education. In other words, the universities have adapted to the changing environments by including new topics, paying more attention to video media, and providing students with more direct field experiences.

LCoS 디스플레이를 이용한 파장선택스위치 (Wavelength Selective Switch using LCoS Display)

  • 이용민
    • 한국산학기술학회논문지
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    • 제15권8호
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    • pp.5288-5293
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    • 2014
  • 본 논문은 차세대 ROADM을 구성하는 핵심기술인 파장선택스위치에서 기존에 사용되는 MEMS소자 기술대신에 LCOS 디스플레이 기술을 적용한 파장선택스위치의 특성을 고찰한 논문이다. LCOS소자를 이용한 5개의 포트를 갖는 파장선택 스위치 시스템을 구성하고 응답특성과 빔제어 특성, insertion loss와 channel isolation등 파장선택 스위치로서의 기본적인 특성들을 검토하였다. 본 파장선택스위치의 응답특성은 11.6 mS 로 양호하며 LCOS상에서의 grating 이미지 패턴에 따른 입사빔의 편향특성이 잘 구현되었다. C밴드내의 40개 채널에 대한 Insertion loss 측정에서 채널에 따라 5.5~12.7 dB 사이의 값이 측정되었으며 인접채널간의 channel isolation 측정은 16~18 dB 값이 측정되었다. 기존의 MEMS소자를 이용한 파장선택스위치 상용화된 제품에 비해 특성은 아직 다소 부족하지만 향후 보완연구에 의해 LCOS소자를 이용한 파장선택스위치 시스템의 기술경쟁력이 충분히 확보될 것으로 기대한다.

인터넷 매장과 오프라인 매장에서의 소비자 의복 쇼핑 성향 차이에 관한 연구 (The Difference of Clothing Shopping Orientation in Internet and Offline Stores)

  • 김세희
    • 한국의류학회지
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    • 제33권1호
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    • pp.92-103
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    • 2009
  • The study is interested in the consumer's mixed choice of the internet and the offline stores. Therefore the purpose of study is to investigate if the clothing shopping orientation of consumers varies when they shop internet and offline, instead of classifying consumers into internet shoppers and offline shoppers. For the purpose, quantitative survey was carried out using 201 questionnaires from men and women in their twenties. The data were analyzed using factor analysis, Pearson's correlation analysis, Spearman's rank order correlation coefficient, t-test, and frequency analysis. The results are as following. First, the clothing shopping orientation structures of offline and internet stores were different each other. As the result of factor analysis, positive, brand oriented, economic, convenient conformity, convenient impulsive factors were extracted from offline store and rational, enjoying, goal oriented, conformity, brand oriented, convenient impulsive purchase factors were extracted from internet store respectively. Second, as the results of investigating the relationship between the clothing shopping orientation structures of offline and internet stores, positive(off)-enjoying(on), brand oriented(off)-brand oriented(on), convenient conformity(off)-conformity(on) had strong correlation s and the rest were peculiar to the each store type. Specifically, the goal oriented factor peculiar to the internet store was noticeable. Third, as the results of investigating the differences between clothing shopping orientation of offline and internet stores, the ranks of strong orientation dimension were different between two channels. As well, the mean differences were significant in goal oriented, conformity, brand oriented, and convenient impulsive purchase dimensions. This study has the significance that it investigated the variance of clothing shopping orientation according to the mixed selection trend of internet/offline.

LMI 방법을 이용한 방사형 인공위성 제어로직 설계 및 강건성 분석 (Radial Type Satellite Attitude Controller Design using LMI Method and Robustness Analysis)

  • 이승우
    • 한국항공우주학회지
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    • 제43권11호
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    • pp.998-1007
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    • 2015
  • 방사형 인공위성 경우, 관성곱이 커서 단일 입 출력 가정이 불가능하기 때문에 고전적 제어기 설계방법을 사용하기 어렵다. 본 논문에서 현대 제어 이론인 $H_{\infty}$ 제어기 설계이론을 사용하여 방사형 인공위성의 자세 제어기 설계를 수행하였다. 설계 알고리즘으로 보다 안정적인 LMI 방법이 사용되었고, 설계 결과에 대한 안정성과 성능에 대한 강건성 해석을 위해 ${\mu}$-해석 방법이 적용되었다. 설계 결과, 일반적인 경우와 다르게 제어기가 포함되지 않은 개루프보다 제어기가 포함된 개루프의 cross-over frequency가 더 낮게 설계되는 것이 관측되었다. 즉 상대적으로 큰 관성곱 영향 때문에 단지 weighting 함수 조정으로 위성 기동성을 증가시키는데 한계가 있는 것으로 해석된다. ${\mu}$-해석을 위해 +/-5%의 관성모멘트 변화를 가정하였다. 안정성 및 성능에 대한 강건성 해석결과, +/-7% 관성모멘트 변화까지 시스템 안정성 및 성능이 보장됨이 확인되었고, 관성곱 변화보다 주관성모멘트 변화가 안정성 및 성능 저하에 더 영향을 주는 것으로 확인되었다.

Performance Analysis of MRT-Based Dual-Polarized Massive MIMO System with Space-Polarization Division Multiple Access

  • Hong, Jun-Ki
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제12권8호
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    • pp.4006-4020
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    • 2018
  • In recent years, one of the most remarkable 5G technologies is massive multiple-input and multiple-output (MIMO) system which increases spectral efficiency by deploying a large number of transmit-antennas (eg. tens or hundreds transmit-antennas) at base station (BS). However, conventional massive MIMO system using single-polarized (SP) transmit-antennas increases the size of the transmit-array proportionally as the number of transmit-antennas increases. Hence, size reduction of large-scale transmit-array is one of the major concerns of massive MIMO system. To reduce the size of the transmit-array at BS, dual-polarized (DP) transmit-antenna can be the solution to halve the size of the transmit-array since one collocated DP transmit-antenna deploys vertical and horizontal transmit-antennas compared to SP transmit-antennas. Moreover, proposed DP massive MIMO system increases the spectral efficiency by not only in the space domain but also in the polarization domain whereas the conventional SP massive MIMO system increases the spectral efficiency by space domain only. In this paper, the comparative performance of DP and SP massive MIMO systems is analyzed by space division multiple access (SDMA) and space-polarization division multiple access (SPDMA) respectively. To analyze the performance of DP and SP massive MIMO systems, DP and SP spatial channel models (SCMs) are proposed which consider depolarized propagation channels between transmitter and receiver. The simulation results show that the performance of proposed 32 transmitter (Tx) DP massive MIMO system improves the spectral efficiency by about 91% for a large number of user equipments (UEs) compare to 32Tx SP massive MIMO system for identical size of the transmit-array.