• Journal of the Earthquake Engineering Society of Korea
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• v.10 no.5 s.51
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• pp.1-9
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• 2006

In this study, axial and lateral loading experiments for both circular and square plain concrete columns confined with carbon fiber tube manufactured by carbon filament winding technique were performed. Based on the test results, reliability analyses to estimate strength reduction factors were carried out by utilizing Monte Carlo technique. CASE I was for plain concrete columns confined with the carbon tubes, CASE II was for reinforced concrete columns confined with the carbon tubes. As results, the strength reduction factors, ${\phi}$, were estimated as 0.7 for CASE I and 0.85 for CASE II respectively.

• Biomedical Science Letters
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• v.10 no.3
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• pp.203-210
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• 2004

It has been reported that glomerulosclerosis mediated by the dysfunction of mesangial cells and insulin-like growth factors (IGFs) are associated with the development of diabetic nephropathy. However, it is not yet known the effect of high glucose on IGF-I, -II secretion, IGF-I receptor, and IGFBPs expression in the mesangial cells. Thus, this study was conducted to examine the effect of high glucose on IGF system and its involvement of protein kinase C (PKC) and oxidative stress in mesangial cells. In this study, high glucose (25 mM) increased IGF-I and IGF-II secretion and mRNA expression (P<0.05), which was blocked by PKC inhibitor (staurosporine, 10/sup -8/ M) and antioxidant (N-acetyl cystein, 10/sup -5/ M). High glucose decreased IGFBP-1 and -2 expression but increased IGFBP-5 expression. These alteration of IGFBPs by high glucose was also prevented by staurosporine and NAC, suggesting the role of PKC and oxidative stress. Indeed, high glucose increased PKC activity. Furthermore, high glucose-induced increase of lipid peroxide (LPO) formation was blocked by PKC inhibitors. In conclusion, high glucose alters IGF system via PKC-oxidative pathways in mesangial cells.

• Journal of Information Technology Services
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• v.4 no.1
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• pp.129-139
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• 2005

This paper proposes a framework of Operational Risk-based Business Continuity System(ORBCS), and develops protection system for operational risk through operational risk assessment and loss distribution approach based on risk management guideline announced in the basel II. In order to find out financial operational risk, business processes of domestic bank are assorted by seven event factors and eight business activities so that we can construct the system. After we find out KRI(Key Risk Indicator) index, tasks and risks, we calculated risk possibility and expected cost by analyzing quantitative data, questionnaire and qualitative approach for AHP model from the past events. Furthermore, we can assume unexpected cost loss by using loss distribution approach presented in the basel II. Each bank can also assume expected loss distributions of operational risk by seven event factors and eight business activities. In this research, we choose loss distribution approach so that we can calculate operational risk. In order to explain number of case happened, we choose poisson distribution, log-normal distribution for loss cost, and estimate model for Monte-Carlo simulation. Through this process which is measured by operational risk. of ABC bank, we find out that loss distribution approach explains closer unexpected cost directly compared than internal measurement approach, and makes less unexpected cost loss.

• Journal of Korean Academy of Nursing
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• v.35 no.5
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• pp.931-942
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• 2005

Purpose: The purpose of this study was to develop a meaning of life scale with high validity and reliability. Method: A conceptual framework composed of 4 phases of meanings of life was identified. And 49 preliminary items on a 4-points scale were developed through content validity. A reliability and validity test of the 49 items was conducted on 564 adults. By means of internal consistency of the 49 items, 1 item was deleted. To verify the 48 items, factor analysis, reliability test, and LISEREL were done. Result: Through exploratory factor analysis of the 48 items, 8 factors were extracted. These factors were labeled as 'self- awareness and self-acceptance', 'hope', 'responsibility awareness', 'love experience', 'self transcendence', 'relation experience', 'self contentedness', and 'Commitment'. Through LISEREL of the 48 items, 2 items were excluded and finally 46 itemsremained. Cronbach's Alpha of the 46 items was .94. The correlation coefficient of the Self-esteem scale was .79. Conclusion: By the above results, the researchers recommend the following: An exploratory study on the variables related to the meaning of life are needed for criterion validity of this scale. Studies on meaning of life of different groupa, and subjects are needed for reverification.

• Biomedical Science Letters
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• v.11 no.2
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• pp.227-235
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• 2005

It has been reported that endurance performance is influenced by various environmental and genetic factors. In view of an important role of human mitochondrial DNA (mtDNA) as a candidate for endurance performance, this study focused on the relationships between $VO_{2max}$ value as a measure of endurance performance or other associated phenotypes and four mtDNA restriction fragment length polymorphisms (RFLPs) (Bam HI, Hinc II1, Hinc II2 and Nci I) in the NADH dehydrogenase subunit 5 and one (Kpn I) in the D-loop region of mtDNA. MtDNA was purified from buffy coat in human peripheral blood, and PCR-RFLP analysis was performed to estimate the allele frequencies of each polymorphism in the mtDNA. There were no significant differences in allele distributions of all polymorphisms studied between male athletes and controls, respectively (P>0.05). However, the Kpn I polymorphism was significantly associated with diastolic blood pressure level in male athletes, respectively (P<0.05). Therefore, our results suggest that this polymorphism might be one of the factors modifying inter-individual difference in cardiovascular risk. Further studies using larger sample size will be required to generalize these results from the study described herein.

• Biomolecules & Therapeutics
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• v.21 no.1
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• pp.35-41
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• 2013

Metformin is widely used for T2D therapy but its cellular mechanism of action is undefined. Recent studies on the mechanism of metformin in T2D have demonstrated involvement of the immune system. Current immunotherapies focus on the potential of immunomodulatory strategies for the treatment of T2D. In this study, we examined the effects of metformin on the antigen-presenting function of antigen-presenting cells (APCs). Metformin decreased both MHC class I and class II-restricted presentation of OVA and suppressed the expression of both MHC molecules and co-stimulatory factors such as CD54, CD80, and CD86 in DCs, but did not affect the phagocytic activity toward exogenous OVA. The class II-restricted OVA presentation-regulating activity of metformin was also confirmed using mice that had been injected with metformin followed by soluble OVA. These results provide an understanding of the mechanisms of the T cell response-regulating activity of metformin through the inhibition of MHC-restricted antigen presentation in relation to its actions on APCs.

• Journal of Biosystems Engineering
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• v.27 no.6
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• pp.547-556
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• 2002

Upright positioning of garlic cloves in mechanical planting has been considered as an essential process because pose of garlic affects not only initial budding and rooting of garlics but quality and yield. Due to the geometrical uniqueness and irregularity of garlic cloves in shape, manual planting operation has been conducted. The overall objective of this research was to determine design factors for designing a garlic clove planter The results are summarized as follows : 1. A vibrating-type clove-metering device was designed and tested. Effects of tilted angle of metering plate and magnitude of vibration on metering performance were investigated. The successful planting rates of the metering device were 96.7% for Hanji varieties. 2. Clove upright-positioning device, posture inducer was designed and tested. When the clearance between the hoppers was set at 4mm, the rates of upright positioning of the device were 92.2% for with Hanji varieties. 3. Optimum metering performance was observed at the plate tilted angle of 80。 with the posture type positioning device.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.11
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• pp.575-583
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• 2020

Vietnam is the country with the largest animal feed production in Southeast Asia. Domestic animal feed manufacturing enterprises play an important role in animal husbandry in particular and in agriculture in general. However, domestic animal feed enterprises in Vietnam are encountering shortcomings. This paper is conducted to investigate the impact levels of external determinants on business performance of domestic animal feed manufacturing enterprises, including: (i) policy and economic mechanism, (ii) supply-demand of animal feed products, and (iii) nature and level of market competition. We presented a research method, explaining the dependent variable 'business performance' and the independent variables. Data were collected from 120 questionnaires from domestic animal feed manufacturing enterprises. Based on these data, we use Cronbach's Alpha, EFA and run regression model for assessing the impact levels of each independent variable on the dependent variable of business performance of domestic animal feed manufacturing enterprises. The results show that three external determinants including (i) policy and economic mechanism, (ii) supply-demand of animal feed products, and (iii) nature and level of market competition, have positive relationships with business performance. Based on the findings, some recommendations are given for improving business performance of domestic animal feed manufacturing enterprises to ensure sustainability.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.12 no.19
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• pp.25-30
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• 1989

This study is concerned with a job sequencing method using the concept of sampling technique. This sampling technique has never been applied to develop the scheduling algorithms. The most job sequencing algorithms have been developed to determine the best or good solution under the special conditions. Thus, it is not only very difficult, but also taken too much time to develop the appropriate job schedules that satisfy the complex work conditions. The application areas of these algorithms are also very narrow. Under these circumstances it is very desirable to develop a simple job sequencing method which can produce the good solution with the short tine period under any complex work conditions. It is called a sampling job sequencing method in this study. This study is to examine the selection of the good job sequence of 1%-5% upper group by the sampling method. The result shows that there is the set of 0.5%-5% job sequence group which has to same amount of performance measure with the optimal job sequence in the case of experiment of 2/n/F/F max. This indicates that the sampling job sequencing method is a useful job sequencing method to find the optimal or good job sequence with a little effort and time consuming. The results of ANOVA show that the two factors, number of jobs and the range of processing time are the significant factors for determining the job sequence at $\alpha$=0.01. This study is extended to 3 machines to machines job shop problems further.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.9
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• pp.217-227
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• 2022

With the aim of examining the effects of implementing international financial reporting standards (IFRS) on teaching accounting and auditing at universities and colleges in Vietnam, a case study was conducted at 30 universities, colleges, and 208 lecturers in Vietnam. Next, the study employed the structural model analysis method by PLS_SEM software to process and analyze the collected data. The research results show that: (1) There are eight factors that affect how IFRS is applied to teaching, including the training program, (ii) teaching staff, (iii) IFRS application regulations, (iv) related party requirements, (v) faculty/school administrators, (vi) teaching aids, (vii) IFRS teaching methods, and (iii) students; (2) there are three factors that affect the quality of teaching staff, including applying IFRS to teaching at the university and colleges, (ii) Regulations on the application of IFRS, (iii) Requirements from related parties. At the same time, the study also shows that, regarding the indirect relationships, applying IFRS to teaching does not play an intermediary role in these relationships. However, at the 10% significance level, it was found that there is an indirect relationship between regulations on the application of IFRS by the Ministry of Finance and the quality of teaching staff through the variable applying IFRS to teaching.