• Title/Summary/Keyword: $II_1$ factors

Search Result 1,407, Processing Time 0.026 seconds

Genetic Relationship between SCCmec Types and Virulence Factors of Methicillin-Resistant Staphylococcus aureus Clinical Isolates in Korea

  • Lim, Kwan-Hun;Lee, Gyu-Sang;Park, Min;Lee, Jin-Hee;Suh, In-Bum;Ryu, Sook-Won;Eom, Yong-Bin;Kim, Jong-Bae
    • Biomedical Science Letters
    • /
    • v.16 no.2
    • /
    • pp.75-82
    • /
    • 2010
  • The molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus (MRSA) isolates have demonstrated their genetic diversity and evolution. A total of 137 strains of MRSA clinical isolates was collected from Korean healthcare facility in 2007. The MRSA clinical isolates were analyzed by molecular typings (SCCmec element and agr locus typing), virule nce factor gene detections {(Panton-Valentine leukocidin (PVL), enterotoxin, exfoliative toxin and toxic shock syndrome toxin-1), and amplified fragment length polymorphism (AFLP)}. The MRSA clinical isolates were classified as SCCmec type II-agr type 1 (2 strains), type II-agr type 2 (79 strains), type III-agr type 1 (24 strains), type III-agr type 2 (2 strains), type IV-agr type 1 (27 strains), type IV-agr type 2 (2 strains), and non-typable (1 strain, agr type 3). Based on SCCmec types, SCCmec type II (95.1%) and III (88.5%) indicated higher multidrug resistance rate than SCCmec type IV (10.3%) (P<0.001). The most common enterotoxin genes were seg (83.8%), sei (83.1%), and sec (80.2%). The tst gene was present in 86 out of 137 (62.8%) MRSA isolates. All MRSA isolates were negative for PVL and exfoliative toxin genes. The combinations of toxin genes were observed in particular SCCmec types; 97.6% of SCCmec type II strains carried sec, seg, sei and tst genes, 73.0% of SCCmec type III strains carried sea gene, and 89.7% of SCCmec type IV strains carried sec, seg and sei genes. Each of the SCCmec types of MRSA isolates had distinct AFLP profile. In conclusion, SCCmec type II, agr type 1 and 2 have demonstrated to be the most common types in Korea, and the results indicated that the virulence factors are closely associated with their molecular types (SCCmec and agr types).

A Study on Work and Family Life of Married Female Production Workers and Policy Implications(II) (대구지역 생산직 기혼여성의 취업 및 가족생활실태파악과 대책수립에 관한 연구(II))

  • 유가효
    • Journal of the Korean Home Economics Association
    • /
    • v.30 no.1
    • /
    • pp.283-309
    • /
    • 1992
  • This study examines work and family life of married women employed in a manufacturing industry. Data were gathered from the use of fact-to-face interview method from a sample of 230 married working women. The major findings of this study can be summarized as follows : (1) With high rates of change of job, most of the respondents remain unstable in their working situation. It was shown that the important factors influencing job satisfaction of married women are women's life cycle, degree of contribution of wife's income toward total family income, and husband's attitude toward wife's empolyment. The degree of job satisfaction is also strongly influenced by labor structural factors such as pay, work environment and fringe benefits. (2) The amount of household labor time was limited by job-related factors rather than by family-related factors, because among these working women employment itself is necessarily for their subsistance. (3) It was shown that wives participated more actively in their marital communications than their husbands. Most of the respondents showed the syncratic type of the decision making patterns, but this results does not necessarily mean wives exercised an equal power with their husbands. The economic factors and the emotional instability of the husband are the ones mostly influencing marital conflicts of the employed women. It was found that the respondents easily revealed marital conflicts related to personal problems of their husbands(such as extramarital affairs, gambling and alchoholism). However, they tried to overcome the structural conflicts related to authoritarian attitudes of their husbands or economic problems without any complaints. (4) Mothers have difficulty in controlling their adolescent children, due to the weakening of parental authority. Although most of the respondents perceived their employment as having negative impacts on their children, they still have high expectations toward their children. Inspite of low degree of father role expectations and facther role performance of their husbands, most of the respondents anticipated expressive roles as well as traditionally instrumental role from their husbands. Finally, these findings would help us determine family welfare policies in Korea. Improvements in paid and household labor structure of married women should be accomplished at the national level. Also, the acting programs for parent education, marital councelling services, and law enforcement for equal employment between men and women should be provided in our society.

  • PDF

Analysis of Factors Affecting Medication Adherence to Improve Life Care in Patients with Hypertension (고혈압 환자의 라이프케어 증진을 위한 약물 순응도 영향요인 분석)

  • Gil, Eun-Ha
    • Journal of Korea Entertainment Industry Association
    • /
    • v.14 no.2
    • /
    • pp.213-224
    • /
    • 2020
  • Purpose: This study is a descriptive and secondary analytical study that uses panel data to identify the factors of medication adherence to improve life care of hypertensive patients. Methods: The subjects of this study were 2,484 patients who were taking medication after hypertension using Korea Medical Panel 2015 data (β-version 1.0). Data analysis was performed using Chi-Square, Scheffe's test, and logistic regression using SPSS/win 22.0. Results: The level of medication adherence in patients with hypertension was 94.2%. The factors of medication adherence were gender and age in Model I of demographic factors, and the presence of disability, smoking, and drinking in Model II. Model III, which added drug use factors, was identified as drinking, drug duration, side effects, drug satisfaction, and payment of drug costs. Conclusion: In order to improve life care for hypertension patients, education and interventions on the importance of take medication and side effects of medications and how to take them will be needed in the early stages of diagnosis.

Analysis of Unmet Healthcare Needs and Risk Factors to Improve the Life Care of Osteoporosis Patients (골다공증 환자의 라이프 케어 증진을 위한 미충족 의료실태와 위험요인 분석)

  • Park, Hyeon-Hee
    • Journal of Korea Entertainment Industry Association
    • /
    • v.14 no.2
    • /
    • pp.225-235
    • /
    • 2020
  • Purpose: This study is a descriptive and secondary analytical study that uses panel data to analysis of unmet healthcare needs and risk factors for improving life care of osteoporosis patients. Methods: The subjects of this study were 941 patients who were diagnosed with osteoporosis using Korea Medical Panel 2015 data(β-version 1.0). Data analysis was performed using Chi-Square and logistic regression using SPSS/win 22.0. Results: The unmet healthcare needs of osteoporosis patients were 22.6%. The factors of unmet healthcare needs were education level and age in Model I of demographic factors, and eating problems, memory problems, activity limitation, and disability in Model II. In Model III, which added socio-psychological factors, eating problems, memory problems, Total family income, and pain/Discomfort were identified. Conclusion: Based on the results of this study, it should be considered in the planning of medical policies to improve the life care of osteoporosis patients, and it is necessary to improve access to medical services and to prevent and mediate realistically to reduce unmet healthcare needs.

A Study on Goods Purchase and Facility Use in Badminton Club Members Using the IPA Matrix Analysis (IPA Matrix 분석을 이용한 배드민턴 생활체육 동호인의 용품구매 및 시설 이용에 관한 연구)

  • Ahn, Yong-Duk;Shin, Jeong-Hun
    • Journal of Korea Entertainment Industry Association
    • /
    • v.15 no.5
    • /
    • pp.115-128
    • /
    • 2021
  • The purpose of this study is to examine the importance and satisfaction perceived in the purchase of goods and the use of a court in badminton club members. The results will be used for basic data to increase club members and present the methods to activate badminton. The survey on goods, price, programs, facilities, staff, and publicity was conducted. The IPA matrix was applied for data processing. The following conclusions were drawn. First, as a result of analyzing the ranking of importance and satisfaction, the first place of importance was coach's professionalism of staff factors, followed by safety of facility factors and program contents and effects of program factors. The first place of satisfaction was cleanliness and management of facility factors, followed by coach's professionalism of staff factors and staff's kindness of staff factors. Second, as a result of the IPA matrix of importance and satisfaction, Quadrant I included appropriateness of training time and program contents and effect of program factors, parking size and cleanliness and management of facility factors, coach's professionalism and staff's service attitude of staff factors, and customer service and complaint resolution of publicity factors. Quadrant II showed appropriateness of price, value for money, and discount policy of price factors and materials and design of goods factors. Quadrant III included excellent customer service of goods of goods factors, various program construction of program factors, court location and accessibility, and various convenient facilities of facility factors, and various publicity and event programs, website construction, and various publicity strategies of publicity factors. Quadrant IV showed brand value of goods, awareness, and brand specialty of goods of goods factors.

Self-perception of the Amount of Medical Aid Use of Outpatient Overusers in Korea (의료급여 외래 과다이용자의 의료이용량에 대한 자기인식)

  • Shin, Sun-Mi;Kim, Eui-Sook;Lee, Hee-Woo
    • Health Policy and Management
    • /
    • v.19 no.2
    • /
    • pp.21-35
    • /
    • 2009
  • Limited studies examined Medical Aid recipients' perception for amount of medical use. This study aimed to identify self-perception(optimal, under and overutilization) for amount, and real amount of medical use, and to determine factors associated with the perception. Subjects were 2,489 Medical Aid recipients among top 2% overusers in 2005. 200 case managers(CM) managing them conducted survey. CM interviewed them using 2005 medical claiming data from the Health Insurance Review & Assessment Service and structured questionnaire. Despite of overusers, perception of overutilization was only 26.9% and 23.6% in Class I and Class II, and that of underutilization was 21.4% and 18.7% respectively. In Class I, monthly total outpatient cost per capita of overutilization perception in 2006 was 206 thousand won higher than 150 thousand won of optimal utilization. Amounts of outpatient visit-days and prescribed cases of overutilization perception were higher than those of optimal and underutilization(p <0.0001). In Class II, overutilization perception had more prescribed cases(p 0.004). After adjustment of confounding factors including age and sex, the associated factors(odds ratio) with overutilization perception were hypertension(1.25), arthritis(1.32), depression(1.66), visit of multi medical institutions(3.09), and those of the underutilization were female(1.34), disabled(1.27), no family support(1.49), living in medium and small city(1.48), experience of unabled-visit to medical institution(2.54), frequent visit-recommendation from physician (1.36). In conclusion, education and consult are needed for subjects to improve the reasonable decision of medical use, and the self-care ability to manage diseases and symptoms. We suggest reinforcing the alternative service in community instead of costly medical institution.

Risk Factors for Colonization and Acquisition with Vancomycin-Resistant Enterococci in Intensive Care Units (중환자실 VRE 균집락과 획득발생 위험요인)

  • Han, Su-Ha;Park, Ho-Ran
    • Journal of Korean Academy of Fundamentals of Nursing
    • /
    • v.15 no.4
    • /
    • pp.522-530
    • /
    • 2008
  • Purpose: In this study active surveillance culture for ICU patients, in whom the risk of VRE infection was high were conducted, and through this the VRE colonization rate and the characteristics of the colonization were examined and risk factors involved in VRE colonization and acquisition were analyzed. Method: This research was performed with 635 patients admitted to ICU between July 1 and December 31, 2006. Results: On admission to ICU, the VRE colonization rate was 2.36%, 93% identified from active surveillance culture. The VRE colonization rate was significantly higher in those patients with cancer (OR=9.43; 95% CI=1.38${\sim}$62.50; P=.022), liver cirrhosis (OR=55.5; 95% CI=7.29${\sim}$500; P=.005), transferred from other hospitals (OR=200; 95% CI=22.73${\sim}$1000; P=.000), high APACHE II score (OR=1.107; 95% CI=1.010${\sim}$1.213; P=.029), or antibiotics within the last 3 months (OR=15.87; 95% CI=2.27${\sim}$111.11; P=.005). The VRE acquisition rate was 5.2%. It was significantly higher in those who were using a ventilator (OR=26.31; 95% CI=5.13${\sim}$142.86; P=.000), three or more kinds of antibiotics during admission (OR=58.82; 95% CI=16.13${\sim}$200; P=.000), or high APACHE II score (OR=1.16; 95% CI=1.08${\sim}$ 1.24; P=.000). Conclusion: The results of this study show that active surveillance culture can detect VRE colonization on admission to ICU and those who have acquired VRE in ICU. The analyzed VRE colonization and risk factors of VRE acquisition are expected to be useful in establishing guidelines for preventing VRE infection in ICU.

  • PDF

Risk Factors Influencing the Delays on the Remodeling Construction Works - Focused on Office Building Projects - (리모델링 공사의 공기지연을 야기하는 리스크 요인 - 오피스 건축물을 중심으로 -)

  • Cho, Kyu-Man;Kim, Tae-Hoo
    • Journal of the Korea Institute of Building Construction
    • /
    • v.18 no.4
    • /
    • pp.385-394
    • /
    • 2018
  • There have been frequent reports of schedule delays due to various risks of remodeling projects, which are different from new construction. Therefore, this study was carried out to analyze the risk factors inherent in the remodeling project and the likelihood of schedule delay occurrence in the remodeling construction work. To analyze the relationship between the risk factors and the likelihood of schedule delays of remodeling projects, (1) a prototype of the office building remodeling work was developed through the analysis of existing case and literature, (2) a questionnaire survey was conducted on 29 construction managers who have been or are currently conducting remodeling projects, and (3) after evaluating the reliability of the collected questionnaire results, the relationship between the two elements, which denotes (i) likelihood of schedule delays per each work, (ii) importance of risk factors, and (iii) risk factors affecting schedule delay in remodeling work, was suggested. Using the results of this study, it is expected to develop a plan for preventing the schedule delay of the office building remodeling work through control the risk factors that may cause schedule delays.

Separation of Amino Acid Enantiomers by Gas Chromatography II (가스크로마토그라피에 의한 아미노산 광학이성체의 분리 II)

  • 박만기;강종성;유재하;박정일;전동원
    • YAKHAK HOEJI
    • /
    • v.30 no.1
    • /
    • pp.47-50
    • /
    • 1986
  • The enantiomers of five amino acids (alanine, valine, threonine, leucine and phenylalanine) could be separated by gas chromatography with optically active (S)-5-isopropyll-$N^3$-phenyl-2-thiohydantoinic stationary phase, which prepared from L-valine and phenylisothiocyanate. Gas chromatographic separations on methylesterificated and N-trifluoroacetylated amino acids have been conducted in isothermal at several column temperatures (180~190, 200, $210^{\circ}C$). The separation factors were 1.29 (alanine, $190^{\circ}C$), 1.35 (valine, $190^{\circ}C$), 1.33 (threonine, $190^{\circ}C$), 1.17 (leucine, $190^{\circ}C$) and 1.05 (phenylalanine, $190^{\circ}C$) and D-isomers eluted prior to L-isomers in every instance. The result of this experiment shows that this stationary phase can be used for the separation of the other amino acids enantiomers.

  • PDF

Effects of Meiotic Stages, Cryoprotectants, Cooling and Vitrification on the Cryopreservation of Porcine Oocytes

  • Huang, Wei-Tung;Holtz, Wolfgang
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.15 no.4
    • /
    • pp.485-493
    • /
    • 2002
  • Different factors may affect the sensitivity of porcine oocytes during cryopreservation. The effect of two methods (cooling and vitrification), four cryoprotectants [glycerol (GLY), 1, 2-propanediol (PROH), dimethyl sulfoxide (DMSO) or ethylene glycol (EG)] and two vitrification media (1 M sucrose (SUC)+8 M EG; 8 M EG) on the developmental capacity of porcine oocytes at the germinal vesicle (GV) stage or after IVM at the metaphase II (M II) stage were examined. Survival was assessed by FDA staining, maturation and cleavage following IVF and IVC. A toxicity test for different cryoprotectants (GLY, PROH, DMSO, EG) was conducted at room temperature before cooling. GV and M II-oocytes were equilibrated stepwise in 1.5 M cryoprotectant and diluted out in sucrose. The survival rate of GV-oocytes in the GLY group was significantly lower (82%, p<0.01) than that of the other group (92 to 95%). The EG group achieved a significantly higher maturation rate (84%, p<0.05) but a lower cleavage rate (34%, p<0.01) than the DMSO group and the controls. For M II-oocytes, the survival rates for all groups were 95 to 99% and the cleavage rate of the GLY group was lower than the PROH-group (21 vs 43%, p<0.01). After cooling to $10^{\circ}C$, the survival rates of GV-oocytes in the cryoprotectant groups were 34 to 51%, however, the maturation rates of these oocytes were low (1%) and none developed after IVF. For M II-oocytes, the EG group showed a significantly higher survival rate than those of the other cryoprotectant groups (40% vs 23-26%, p<0.05) and the cleavage rates of PROH, DMSO and EG group reached only 1 to 2%. For a toxicity test of different vitrification media, GV and M II-oocytes were equilibrated stepwise in 100% 8 M EG (group 1) and 1 M SUC + 8 M EG (group 2) or equilibrated in sucrose and then in 8 M EG (SUC+8 M EG, group 3). For GV-oocytes, the survival, maturation and cleavage rates of Group 1 were significantly lower than those in group 2, 3 and control group (p<0.05). For M II-oocytes, there were no differences in survival, maturation and cleavage rates between groups. After vitrification, the survival rates of GV and M II-oocytes in group 2 and 3 were similarly low (4-9%) and none of them matured nor cleaved after in vitro maturation, fertilization and culture. In conclusion, porcine GV and M II-oocytes do not seem to be damaged by a variety of cryoprotectants tested, but will succumb to a temperature decrease to $10^{\circ}C$ or to the process of vitrification, regardless of the cryoprotectant used.