• 대한의생명과학회지
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• 제16권2호
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• pp.75-82
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• 2010

The molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus (MRSA) isolates have demonstrated their genetic diversity and evolution. A total of 137 strains of MRSA clinical isolates was collected from Korean healthcare facility in 2007. The MRSA clinical isolates were analyzed by molecular typings (SCCmec element and agr locus typing), virule nce factor gene detections {(Panton-Valentine leukocidin (PVL), enterotoxin, exfoliative toxin and toxic shock syndrome toxin-1), and amplified fragment length polymorphism (AFLP)}. The MRSA clinical isolates were classified as SCCmec type II-agr type 1 (2 strains), type II-agr type 2 (79 strains), type III-agr type 1 (24 strains), type III-agr type 2 (2 strains), type IV-agr type 1 (27 strains), type IV-agr type 2 (2 strains), and non-typable (1 strain, agr type 3). Based on SCCmec types, SCCmec type II (95.1%) and III (88.5%) indicated higher multidrug resistance rate than SCCmec type IV (10.3%) (P<0.001). The most common enterotoxin genes were seg (83.8%), sei (83.1%), and sec (80.2%). The tst gene was present in 86 out of 137 (62.8%) MRSA isolates. All MRSA isolates were negative for PVL and exfoliative toxin genes. The combinations of toxin genes were observed in particular SCCmec types; 97.6% of SCCmec type II strains carried sec, seg, sei and tst genes, 73.0% of SCCmec type III strains carried sea gene, and 89.7% of SCCmec type IV strains carried sec, seg and sei genes. Each of the SCCmec types of MRSA isolates had distinct AFLP profile. In conclusion, SCCmec type II, agr type 1 and 2 have demonstrated to be the most common types in Korea, and the results indicated that the virulence factors are closely associated with their molecular types (SCCmec and agr types).

• 대한가정학회지
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• 제30권1호
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• pp.283-309
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• 1992

This study examines work and family life of married women employed in a manufacturing industry. Data were gathered from the use of fact-to-face interview method from a sample of 230 married working women. The major findings of this study can be summarized as follows : (1) With high rates of change of job, most of the respondents remain unstable in their working situation. It was shown that the important factors influencing job satisfaction of married women are women's life cycle, degree of contribution of wife's income toward total family income, and husband's attitude toward wife's empolyment. The degree of job satisfaction is also strongly influenced by labor structural factors such as pay, work environment and fringe benefits. (2) The amount of household labor time was limited by job-related factors rather than by family-related factors, because among these working women employment itself is necessarily for their subsistance. (3) It was shown that wives participated more actively in their marital communications than their husbands. Most of the respondents showed the syncratic type of the decision making patterns, but this results does not necessarily mean wives exercised an equal power with their husbands. The economic factors and the emotional instability of the husband are the ones mostly influencing marital conflicts of the employed women. It was found that the respondents easily revealed marital conflicts related to personal problems of their husbands(such as extramarital affairs, gambling and alchoholism). However, they tried to overcome the structural conflicts related to authoritarian attitudes of their husbands or economic problems without any complaints. (4) Mothers have difficulty in controlling their adolescent children, due to the weakening of parental authority. Although most of the respondents perceived their employment as having negative impacts on their children, they still have high expectations toward their children. Inspite of low degree of father role expectations and facther role performance of their husbands, most of the respondents anticipated expressive roles as well as traditionally instrumental role from their husbands. Finally, these findings would help us determine family welfare policies in Korea. Improvements in paid and household labor structure of married women should be accomplished at the national level. Also, the acting programs for parent education, marital councelling services, and law enforcement for equal employment between men and women should be provided in our society.

• 한국엔터테인먼트산업학회논문지
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• 제14권2호
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• pp.213-224
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• 2020

본 연구는 고혈압 환자의 라이프케어 증진을 위한 약물 순응도 영향요인을 파악하기 위하여 패널 데이터를 활용한 서술적, 2차 분석 조사연구이다. 연구대상자는 한국의료패널 2015년 데이터(β-version 1.0)를 활용하여 고혈압 진단 후 약물을 복용하고 있는 2,484명을 대상으로 하였다. 자료분석은 SPSS/win 22.0을 이용하여 Chi-Square, Scheffe's test, logistic regression으로 하였다. 연구결과 고혈압 환자의 약물 순응도 수준은 94.2%로 나타났으며 약물 순응도 영향요인은 인구학적 요인의 Model I에서는 성별, 나이로 나타났고 신체-사회적 요인을 추가한 Model II에서는 장애유무, 흡연, 음주여부로 나타났으며 약물복용 요인을 추가한 Model III에서는 음주여부, 약물복용 기간, 부작용 발생, 약물 만족도, 약제비 지불 부담으로 확인되었다. 본 연구결과를 바탕으로, 고혈압 환자가 라이프케어를 증진시켜 합병증이 발생하지 않도록 고혈압 진단 초기부터 개개인의 특성에 맞춰 약물복용의 중요성 및 부작용, 복용 방법 등에 대한 교육과 중재가 필요하겠다.

• 한국엔터테인먼트산업학회논문지
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• 제14권2호
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• pp.225-235
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• 2020

본 연구는 골다공증 환자의 라이프 케어 증진을 위한 미충족 의료실태와 위험요인 분석하기 위하여 패널 자료를 활용한 횡단적 2차 분석 조사연구이다. 연구대상자는 한국의료패널 2015년 자료(β-version 1.0)를 활용하여 골다공증 진단을 받은 941명을 대상으로 하였다. SPSS/win 22.0 Program을 이용하여 χ² test, logistic regression을 이용하여 자료를 분석하였다. 연구결과 골다공증 환자의 미충족 의료 발생률은 22.6%이었으며, 인구학적 특성 요인의 Model I에서는 나이, 교육수준으로 나타났으며, 신체적 요인을 추가한 Model II에서는 섭식문제, 기억력 장애, 활동제한, 장애 판정으로 나타났다. 심리·사회적 요인을 추가한 Model III에서는 섭식문제, 기억력 장애, 총 가구 소득, 통증/불편감으로 확인되었다. 본 연구 결과를 바탕으로 골다공증 환자의 라이프 케어를 증진시키기 위해 지속적으로 의료정책 기획 시 고려되어져야 하겠으며, 미충족 의료를 감소시키기 위한 의료서비스 접근성 개선과 현실적인 예방 및 중재가 필요하겠다.

• 한국엔터테인먼트산업학회논문지
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• 제15권5호
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• pp.115-128
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• 2021

본 연구는 배드민턴 생활체육 동호인의 용품구매와 시설 이용 시 생각하고 느낀 중요도와 만족도를 알아보고 이를 기초자료로 활용하여 생활체육 배드민턴 동호인을 확대하고 활성화 방안을 제안하고자 용품, 가격, 프로그램, 시설, 직원, 홍보에 대한 설문조사를 진행하였다. 설문조사 후 중요도와 만족도를 알아보기 위하여 IPA Matrix방법을 적용하여 자료처리를 실시하였으며, 다음과 같은 결론을 얻었다. 첫째, 배드민턴 생활체육 동호인의 중요도와 만족도 순위 분석결과 중요도는 1위 직원요인의 강사 및 지도자의 전문성, 2위 시설요인의 시설의 안전성, 3위는 프로그램의 프로그램 내용 및 효과 만족도는 1위 시설요인의 시설의 청결 및 관리, 2위 직원요인의 강사 및 지도자의 전문성, 3위는 직원요인의 직원의 친절성 순으로 나타났다. 둘째, 중요도와 만족도 IPAMatrix 결과 I사분면은 프로그램요인의 강습시간 적절성과 프로그램 내용 및 효과, 시설요인의 주차 공간 규모와 시설의 청결 및 관리, 직원요인의 강사 및 지도자의 전문성, 직원서비스 태도, 직원친절성, 홍보요인의 소비자와의 상담 및 불편사항 해결, II사분면은 가격요인의 가격의 적절성, 가격대비 가치, 할인제도, 용품요인의 소재 및 디자인, III사분면은 용품요인의 용품 A/S 우수성, 프로그램요인의 프로그램 구성의 다양성, 시설요인의 배드민턴 구장 위치 및 접근성, 다양한 편의시설, 홍보요인의 다양한 홍보 및 이벤트 구성과 홈페이지 구성 등 홍보 전략, IV사분면은 용품요인의 용품 브랜드 가치 및 인지도와 용품 브랜드 전문성이 나타났다.

• 보건행정학회지
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• 제19권2호
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• pp.21-35
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• 2009

Limited studies examined Medical Aid recipients' perception for amount of medical use. This study aimed to identify self-perception(optimal, under and overutilization) for amount, and real amount of medical use, and to determine factors associated with the perception. Subjects were 2,489 Medical Aid recipients among top 2% overusers in 2005. 200 case managers(CM) managing them conducted survey. CM interviewed them using 2005 medical claiming data from the Health Insurance Review & Assessment Service and structured questionnaire. Despite of overusers, perception of overutilization was only 26.9% and 23.6% in Class I and Class II, and that of underutilization was 21.4% and 18.7% respectively. In Class I, monthly total outpatient cost per capita of overutilization perception in 2006 was 206 thousand won higher than 150 thousand won of optimal utilization. Amounts of outpatient visit-days and prescribed cases of overutilization perception were higher than those of optimal and underutilization(p <0.0001). In Class II, overutilization perception had more prescribed cases(p 0.004). After adjustment of confounding factors including age and sex, the associated factors(odds ratio) with overutilization perception were hypertension(1.25), arthritis(1.32), depression(1.66), visit of multi medical institutions(3.09), and those of the underutilization were female(1.34), disabled(1.27), no family support(1.49), living in medium and small city(1.48), experience of unabled-visit to medical institution(2.54), frequent visit-recommendation from physician (1.36). In conclusion, education and consult are needed for subjects to improve the reasonable decision of medical use, and the self-care ability to manage diseases and symptoms. We suggest reinforcing the alternative service in community instead of costly medical institution.

• 기본간호학회지
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• 제15권4호
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• pp.522-530
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• 2008

Purpose: In this study active surveillance culture for ICU patients, in whom the risk of VRE infection was high were conducted, and through this the VRE colonization rate and the characteristics of the colonization were examined and risk factors involved in VRE colonization and acquisition were analyzed. Method: This research was performed with 635 patients admitted to ICU between July 1 and December 31, 2006. Results: On admission to ICU, the VRE colonization rate was 2.36%, 93% identified from active surveillance culture. The VRE colonization rate was significantly higher in those patients with cancer (OR=9.43; 95% CI=1.38${\sim}$62.50; P=.022), liver cirrhosis (OR=55.5; 95% CI=7.29${\sim}$500; P=.005), transferred from other hospitals (OR=200; 95% CI=22.73${\sim}$1000; P=.000), high APACHE II score (OR=1.107; 95% CI=1.010${\sim}$1.213; P=.029), or antibiotics within the last 3 months (OR=15.87; 95% CI=2.27${\sim}$111.11; P=.005). The VRE acquisition rate was 5.2%. It was significantly higher in those who were using a ventilator (OR=26.31; 95% CI=5.13${\sim}$142.86; P=.000), three or more kinds of antibiotics during admission (OR=58.82; 95% CI=16.13${\sim}$200; P=.000), or high APACHE II score (OR=1.16; 95% CI=1.08${\sim}$ 1.24; P=.000). Conclusion: The results of this study show that active surveillance culture can detect VRE colonization on admission to ICU and those who have acquired VRE in ICU. The analyzed VRE colonization and risk factors of VRE acquisition are expected to be useful in establishing guidelines for preventing VRE infection in ICU.

• 한국건축시공학회지
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• 제18권4호
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• pp.385-394
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• 2018

오피스 건축물의 리모델링 사업에서, 신축과는 다른 리모델링 사업의 다양한 리스크로 인해 공기가 지연되는 사례가 빈번하게 보고되고 있다. 이에 본 연구에서는 리모델링 프로젝트의 리스크 요인들과 리모델링 공사의 작업별 공기지연 발생가능성의 관계를 분석하고자 수행되었다. 리모델링 사업의 경험이 있는 29명의 전문가 면담결과의 과학적 통계적 분석을 통해, 리모델링 사업의 리스크 요인과 그로 인한 작업별 공기지연 가능성을 크게 3가지 측면에서 분석하였다. 즉, (i) 리모델링 공사의 작업별 공기지연 가능성, (ii) 리모델링 공사의 리스크 요인별 중요도, (iii) 리모델링 공사의 공기지연에 영향을 미치는 리스크 요인 등 세가지 분석결과를 제시하였다.

• 약학회지
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• 제30권1호
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• pp.47-50
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• 1986

The enantiomers of five amino acids (alanine, valine, threonine, leucine and phenylalanine) could be separated by gas chromatography with optically active (S)-5-isopropyll-$N^3$-phenyl-2-thiohydantoinic stationary phase, which prepared from L-valine and phenylisothiocyanate. Gas chromatographic separations on methylesterificated and N-trifluoroacetylated amino acids have been conducted in isothermal at several column temperatures (180~190, 200, $210^{\circ}C$). The separation factors were 1.29 (alanine, $190^{\circ}C$), 1.35 (valine, $190^{\circ}C$), 1.33 (threonine, $190^{\circ}C$), 1.17 (leucine, $190^{\circ}C$) and 1.05 (phenylalanine, $190^{\circ}C$) and D-isomers eluted prior to L-isomers in every instance. The result of this experiment shows that this stationary phase can be used for the separation of the other amino acids enantiomers.

• Asian-Australasian Journal of Animal Sciences
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• 제15권4호
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• pp.485-493
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• 2002

Different factors may affect the sensitivity of porcine oocytes during cryopreservation. The effect of two methods (cooling and vitrification), four cryoprotectants [glycerol (GLY), 1, 2-propanediol (PROH), dimethyl sulfoxide (DMSO) or ethylene glycol (EG)] and two vitrification media (1 M sucrose (SUC)+8 M EG; 8 M EG) on the developmental capacity of porcine oocytes at the germinal vesicle (GV) stage or after IVM at the metaphase II (M II) stage were examined. Survival was assessed by FDA staining, maturation and cleavage following IVF and IVC. A toxicity test for different cryoprotectants (GLY, PROH, DMSO, EG) was conducted at room temperature before cooling. GV and M II-oocytes were equilibrated stepwise in 1.5 M cryoprotectant and diluted out in sucrose. The survival rate of GV-oocytes in the GLY group was significantly lower (82%, p<0.01) than that of the other group (92 to 95%). The EG group achieved a significantly higher maturation rate (84%, p<0.05) but a lower cleavage rate (34%, p<0.01) than the DMSO group and the controls. For M II-oocytes, the survival rates for all groups were 95 to 99% and the cleavage rate of the GLY group was lower than the PROH-group (21 vs 43%, p<0.01). After cooling to $10^{\circ}C$, the survival rates of GV-oocytes in the cryoprotectant groups were 34 to 51%, however, the maturation rates of these oocytes were low (1%) and none developed after IVF. For M II-oocytes, the EG group showed a significantly higher survival rate than those of the other cryoprotectant groups (40% vs 23-26%, p<0.05) and the cleavage rates of PROH, DMSO and EG group reached only 1 to 2%. For a toxicity test of different vitrification media, GV and M II-oocytes were equilibrated stepwise in 100% 8 M EG (group 1) and 1 M SUC + 8 M EG (group 2) or equilibrated in sucrose and then in 8 M EG (SUC+8 M EG, group 3). For GV-oocytes, the survival, maturation and cleavage rates of Group 1 were significantly lower than those in group 2, 3 and control group (p<0.05). For M II-oocytes, there were no differences in survival, maturation and cleavage rates between groups. After vitrification, the survival rates of GV and M II-oocytes in group 2 and 3 were similarly low (4-9%) and none of them matured nor cleaved after in vitro maturation, fertilization and culture. In conclusion, porcine GV and M II-oocytes do not seem to be damaged by a variety of cryoprotectants tested, but will succumb to a temperature decrease to $10^{\circ}C$ or to the process of vitrification, regardless of the cryoprotectant used.