• Title/Summary/Keyword: $F_0$ change

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Brain Activation Evoked by Sensory Stimulation in Patients with Spinal Cord Injury : Functional Magnetic Resonance Imaging Correlations with Clinical Features

  • Lee, Jun Ki;Oh, Chang Hyun;Kim, Ji Yong;Park, Hyung-Chun;Yoon, Seung Hwan
    • Journal of Korean Neurosurgical Society
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    • v.58 no.3
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    • pp.242-247
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    • 2015
  • Objective : The purpose of this study is to determine whether the changes of contralateral sensorimotor cortical activation on functional magnetic resonance imaging (fMRI) can predict the neurological outcome among spinal cord injury (SCI) patients when the great toes are stimulated without notice. Methods : This study enrolled a total of 49 patients with SCI and investigated each patient's preoperative fMRI, postoperative fMRI, American Spinal Injury Association (ASIA) score, and neuropathic pain occurrence. Patients were classified into 3 groups according to the change of blood oxygenation level dependent (BOLD) response on perioperative fMRI during proprioceptive stimulation with repetitive passive toe movements : 1) patients with a response of contralateral sensorimotor cortical activation in fMRI were categorized; 2) patients with a response in other regions; and 3) patients with no response. Correlation between the result of fMRI and each parameter was analyzed. Results : In fMRI data, ASIA score was likely to show greater improvement in patients in group A compared to those belonging to group B or C (p<0.001). No statistical significance was observed between the result of fMRI and neuropathic pain (p=0.709). However, increase in neuropathic pain in response to the signal change of the ipsilateral frontal lobe on fMRI was statistically significant (p=0.030). Conclusion : When there was change of BOLD response at the contralateral sensorimotor cortex on perioperative fMRI after surgery, relief of neurological symptoms was highly likely for traumatic SCI patients. In addition, development of neuropathic pain was likely to occur when there was change of BOLD response at ipsilateral frontal lobe.

Hyperfine Interaction Integrals for NMR Chemical Shifts in 5f Paramagnetic Systems

  • 이기학;이지영;김동희
    • Bulletin of the Korean Chemical Society
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    • v.18 no.4
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    • pp.424-427
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    • 1997
  • To study the NMR chemical shift arising from the 5f-electron orbital angular momentum and the 5f-electron spin dipolar-nuclear spin angular momentum interactions, the evaluation of the hyperfine integrals has been extended to any pairs of SCF type 5f orbitals adopting a general method which is applicable to a general vector R, pointing in any direction in space. From the electronic wavefunctions for 5f orbitals expressed in common coordinate system, the radial part of the hyperfine interaction integrals are derived by translating the exponential part, r2 exp(-2βr), in terms of R, rN and the modified Bessel functions. The radial integals for 5f orbitals are tabulated in analytical forms. When two of the hyperfine integrals along the (100), (010), (001), (110), and (111) axes are calculated using the derived radial integrals, the calculated values for the 5f system change sign for R-values larger than R 0.35 nm. But the calculated values for the 4f systems change sign for R-values larger than R 0.20 nm.

Study of OLED luminescence efficiency by electron Injection layer change (유기발광 소자의 전자 주입층 두께 변화에 따른 발광효율 연구)

  • Lee, Jung-Ho
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2004.11a
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    • pp.555-558
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    • 2004
  • The efficiency of electron injection from the cathode is strongly dependent on the thickness of the LiF buffer-layer. We used LiF to electron Injection layer. We compared characteristics of organic light emitting device changing LiF thin film thickness from 1.0 m to 10.0 nm. Experiment result, we found that LiF thickness has the optimized electrical characteristics in 3.0 m. In this paper, we did research about electrical characteristics of organic light emitting device by LiF thickness change using method numerical analysis method. We proved adequate experimental results that compare results of numerical analysis, and come out through an experiment results is validity.

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Single and Four-Week Subcutaneous Toxicity Studies of a Bee Venom Extracts (F1, F3) In Rats (봉독 추출물(Fl, F3)의 랫드에 대한 단회 및 4주 반복 피하 투여 독성시험)

  • 박기수;조성대;안남식;정지원;양세란;박준석;홍인선;서민수;조은혜
    • Toxicological Research
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    • v.19 no.1
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    • pp.51-66
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    • 2003
  • This study was performed to evaluate single and repeated-dose toxicities of Bee Venom Extracts (F1, F3) in Spraque-Dawley. F1 was injected subcutaneously to rat at dose levels of 0, 0.0002, 0.002, 0.02 mg/kg/day for single-dose toxicity study and repeated-dose toxicity study. F3 was injected subcutaneously to rat at dose level of 0, 0.003, 0.03, 0.3 mg/kg/day for single-dose toxicity study and repeated-dose toxicity study. In both studies, there were no dose related changes in mortality, clinical sign, body weight change, food and water consumption, opthalmoscopy, organ weights, urine analysis, biochemical examination, and hematological findings of all animals treated with Bee Venom (F1, F3). Gross and histopathological findings revealed no evidence of specific toxicity related to Bee Venom (F1, F3). These results suggest that the subcutaneous NOEL (No Observed Effect Level) of Bee Venom (F1, F3) may be over F1 -0.02 mg/kg, F3-0.3 mg/kg.

A Study on the Trend Change Point of NBUE-property

  • Kim, Dae-Kyung
    • Communications for Statistical Applications and Methods
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    • v.3 no.2
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    • pp.275-282
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    • 1996
  • A life distribution F with survival function $\overline{F}$=1-F, finite mean $\mu$ and mean residual life m(t) is said to be NBUE(NWUE) if m(t)$\leq$($\geq$) .$\mu$ for t$\geq$0. This NBUE property can equivalently be characterized by the fact that $\varphi$(u)$\geq$($\leq$)u for 0$\leq$u$\leq$1, where $\varphi$(u) is the scaled total-time-on test transform of F. A generalization of the NBUE properties is that there is a value of p such that $\varphi$(u)\geq.u$ for 0$\leq$u$\leq$p and $\varphi$(u)\leq$$\leq$u$\leq$1, or vice versa. This means that we have a trend change in the NBUE property. In this paper we point out an error of Klefsjo's paper (1988). He erroneously takes advantage of trend change point of failure rate to calculate the empirical test size and power in lognormal distribution. We solves the trend change point of mean residual lifetime and recalculate the empirical test size and power of Klefsjo (1988) in mocensoring case.

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Health Promotion Lifestyle Profiles of the Korean Elderly in Japan (일본에 거주하는 한국 노인의 건강증진 생활양식)

  • Jaung, Ae-Hwa;Park, Kyung-Min;Ryu, Mi-Kyung
    • Research in Community and Public Health Nursing
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    • v.11 no.2
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    • pp.470-485
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    • 2000
  • The purpose of this study was to investigate health promotion lifestyle profiles of the Korean elderly in Japan. The subjects of this study were 202 elders in Aichi prefecture. The method of this study questionnaires interviews, and a self-administered questionnaire from the 1st to the 20th of April in 2000. This study tool was based on Walker et al. (1987)'s Health Promotion lifestyle Profiles (HPLP). Analysis of the data used an SPSS/pc+ WIN 9.0 program. Data analyses were conducted by using frequency, percentage, t-test, ANOVA. Pearson correlation, Kendal tau and Stepwise Multiple Regression. The results were as follows: 1. The average score of Health Promotion Lifestyle Profiles of Korean elderly in Japan was 2.72(SD=0.40). On the sub-scale of Health Promotion Lifestyle Profiles: nutrition(M = 3. 06), self-actualization(M =2.99), interpersonal support (M=2.81), stress management (M=2.68) revealed higher scores, whereas the scores of health responsibility(M=2.52), and exercise(M=1.92) were lower. 2. Health Promotion Lifestyle Profiles were significantly different by age (F = 11. 02, p = .000), religion(F=2.96, p=.033), occupation(F=6.91, p=.000), living family status(F=13.07, p=.000), living family number(F=11.74, p=.000), monthly pocket money(F=18.79, p=.000), the source of pocket money (F=7.18, p=.000), and the length of residence(F=9.79, p=.000). 3. Health Promotion Lifestyle Profiles was significantly predicted by monthly pocket money($r^2$ change =0. 188, p=.000), sex($r^2$ change= 0.066, p= .000), the length of residence($r^2$ change = 0.059, p = .000), the source of pocket money($r^2$ change=0.036, p= .000), age ($r^2$ change=0.018, p=.000). These variables showed a positive correlation with health promotion lifestyle profiles of the Korean elderly in Japan. These variables explained 36.7% of the variance of Health Promotion Lifestyle Profiles. On the basis of the above findings, Health Promotion Lifestyle Profiles programs for Korean elderly in Japan needs be to developed with Japanese social-culture perspectives and needs to develop an intervention method to improve Health Promotion Lifestyle Profiles. It is also suggested that further research is required.

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Influence of Organic Acids Residual Concentration by the Change of F/M Ratio on Sludge Settleability in Advanced Sewage Treatment Processes (하.폐수 고도처리시 F/M비 변화에 따른 유기산 잔류 농도가 슬러지 침강성에 미치는 영향)

  • Park, Young-Ki;Kim, Young-Il;Kim, Sl-Ki
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.1
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    • pp.42-47
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    • 2006
  • The biological nutrient treatment is formed with repetition and rearrangement of anaerobic, anoxic and oxic tank. In this case, VFAs is generated in the anaerobic tank and the anoxic tank. The VFAs is an important factor for removal of nitrogen and phosphate and SVI. So, in this study I investigated to find a relationship among the generation rate of the VFAs according to the change of F/M ratio and the characteristic which can eliminate organic matter and nitrogen according to the change of residual concentration of the VFAs and the efficiency of the process and also SVI in wastewater treatment. $A^2/O$ process was used for wastewater treatment. F/M ratio was under the control of the change of MLSS concentration. When the F/M ratio was changed from 0.16 to 0.08 kg-BOD/kg-MLSS/day, the VFAs's production volume increased based on the reduction of F/M ratio in batch reaction. And the residual concentration of the VFAs decreased at first and then increased later. SVI and SS were high when F/M ratio was $0.16kg/kg{\cdot}d$ and showed stable status when F/M ratio decreased $0.11{\sim}0.13kg/kg{\cdot}d$. However, SVI and SS continuously increased with decrease of F/M ratio and were high at $0.08kg/kg{\cdot}d$. In the result of comparison between residual concentration of the VFAs and denitrification rate in anoxic tank, the less residual volume of the VFAs was in anoxic tank, the higher denitrification ratio became. The optimal residual-concentration of the VFAs considering SVI and removal efficiency of nitrogenwas $1.4{\sim}2.2mg/L$. At that time F/M ratio was $0.11{\sim}0.13$ kg-BOD/kg-MLSS/day.

Test for Trend Change in NBUE-ness Using Randomly Censored Data

  • Dae-Kyung Kim;Dong-Ho Park;June-Kyun Yum
    • Communications for Statistical Applications and Methods
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    • v.2 no.2
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    • pp.1-12
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    • 1995
  • Let F be a life distribution with finite mean $\mu$ Then F is said to be in new better then worse than used in expectation (NBWUE(p)) class if $\varphi(u) {\geq} u$ for $0 {\leq}u{\leq}t_0$ and ${\varphi}(u) {\leq} u$ for $t_0< u {\leq} 1$ where ${\varphi}(u)$ is the scaled total-time-on-test transform and $p=F(t_0)$. We propose a testing procedure for $H_0$ : F is exponential against $H_1$ : NBWUE(p), and is not expontial, (or $H_1\;'$ : F is NWBUE (p), and is not exponential) using randomly censored data. Our procedure assumes kmowledge of the proportion p of the population that fail at or before the change-point $\t_0$. Know ledge of $\t_0$ itself is not assumed. The asymptotic normality of the test statistic is established and a Monte Carlo experiment is performed to investigate the speed of convergence of the test statistic to normality. The power of our test is also studied.

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Characterization of the Ryanodine Receptor and SERCA in Fetal, Neonatal, and Adult Rat Hearts

  • Ramesh, Venkat;Kresch, Mitchell J.;Park, Woo-Jin;Kim, Do-Han
    • BMB Reports
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    • v.34 no.6
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    • pp.573-577
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    • 2001
  • The mammalian heart is known to undergo significant mechanical changes during fetal and neonatal development. The objective of this study was to define the ontogeny of the ryanodine receptor/$Ca^{2+}$ release channel and SERCA that play the major roles in excitation-contraction coupling. Whole ventricular homogenates of fetal (F) (19 and 22 days in gestation), postnatal (N) (1 and 7 days postnatal), and adult (A) (5 weeks postnatal) Sprague-Dawley rat hearts were used to study [$^3H$]ryanodine binding and oxalate-supported $^{45}Ca^{2+}$ uptake. For the ryanodine receptor, the major findings were: (1) The ryanodine receptor density, as determined by maximal [$^3H$]ryanodine binding ($B_{max}$), increased 3 fold between the F22 and A periods ($0.26{\pm}0.1$ vs. $0.73{\pm}0.07$ pmoles/mg protein, p<0.01), whereas there was no significant change during the F22 and N1 development phases ($0.26{\pm}0.1$ vs. $0.34{\pm}0.01$). (2) Affinity of the ryanodine receptor to ryanodine did not significantly change, as suggested by the lack of change in the $K_d$ during the development and maturation. For SERCA, changes started early with an increased rate of $Ca^{2+}$ uptake in the fetal periods (F19: $8.1{\pm}1.1$ vs. F22: $19.3{\pm}2.2$ nmoles/g protein/min; p<0.05) and peaked by 7 days (N7) of the postnatal age ($34.9{\pm}2.1$). Thus, we conclude that the quantitative changes occur in the ryanodine receptor during myocardial development. Also, the maturation of the $Ca^{2+}$ uptake appears to start earlier than that of the $Ca^{2+}$ release.

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Impacts of Korean Somatotype in Energy Consumption and Hormone Changes During Treadmill Gait -Around University Students-

  • Choi, Yoo-Rim;Choi, Wan-Suk
    • The Journal of Korean Physical Therapy
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    • v.23 no.6
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    • pp.85-92
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    • 2011
  • Purpose: This study is executed to examine the effects of Korean somatotype on energy consumption and hormone changes during treadmill gait. Methods: The objects of study were a total of 70 university students in their 20s and 30s divided into 7 groups according to somatotype with 10 members each, 4 groups of male (M1, M2, M3, M4) and 3 groups of female (F1, F2, F3). Results: In case of male groups, there was a significant difference in VO2 and VCO2 between group M1, M2 and M3 (p<0.05). There was also a meaningful difference between Phase1 and Phase2, Phase3 and Phase4 in a phase (p<0.01). In case of female groups, there was a meaningful difference in VO2 between F1 and F2, F3 (p<0.01). There was also a significant difference between Phase1 and Phase2, Phase3 and Phase4 in a phase (p<0.01). There was no significant difference in VCO2 among them, but there was a significant difference in it between Phase1 and Phase2, Phase3 and Phase4 (p<0.01). There was equally no significant difference in the concentration of adrenaline and nor-adrenaline among both male and female groups, but such concentration showed meaningful difference before and after exercise (p<0.01). Conclusion: Energy consumption differs according to somatotype. There is a difference in hormone change, indicating that somatotype has effects on the physiological change. Therefore, in future exercise should be executed in more diverse conditions to further study somatotype with energy consumption and the correlations of hormone change.