• Tuberculosis and Respiratory Diseases
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• v.61 no.3
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• pp.227-232
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• 2006

Background: In the measurement of bronchodilator reversibility, the forced expiratory volume in one second($FEV_{1}$) and the forced vital capacity(FVC) are commonly used parameters and recommended criteria for the reversibility requiring an increase of more than 200ml and 12% above the baseline, respectively. However, aged patients do not often meet the criteria of an increase in volume(>200ml) even though the medical history of that patient is adequate for asthma. This study investigated the role of the forced expiratory volume in six seconds($FEV_{6}$) in the bronchodilator reversibility test in elderly patients. Methods: A total of 236 patients more than 65 years of age with a $FEV_{1}$/FVC ratio<80% were enrolled in this study. The bronchodilator revesibility tests were examined. With the setting $FEV_{1}$ as the baseline, the patients were divided into three groups; Group I : $$FEV_{1}{\geq_-}80%$$ of the predicted value, Group II : 60%<$FEV_{1}$<80% of the predicted value, Group III : $$FEV_{1}{\leq_-}60%$$ of the predicted value. Results: Positive reversibility in the $FEV_{1}$, $FEV_{6}$, and FVC was in 33(14.0%), 49(20.8%) and 55(23.3%). However, Group III presented with reversibility in the $FEV_{1}$, $FEV_{6}$, and FVC in 15(22.4%), 30(44.8%) and 32(47.8%) respectively. Conclusions: The $FEV_{6}$ might be used as a complementary parameter in bronchodilatror reversibility in elderly patients. However, more study will be needed to determine the usefulness of $FEV_{6}$ in bronchodilator reversibility test.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.2
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• pp.169-176
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• 2022

Purpose : The purpose of this study is to investigate the effect of squat, bracing and aerobic exercise on lung function, which is known to be effective for strength training, on lung function. Methods : The study was conducted with 33 students from Busan K university. Eleven students were assigned to squats, bracing, and aerobic exercise, six weeks three times a week. In order to measure lung activity, pony Fx manufactured the change amount of FVC (forced vital capacity), FEV₁ (Forced expiratory volume at one second), and FEV₁/FVC % (forced vital capacity/forced expiratory volume at one second) was analyzed after inputting the information of experimental group A and B controls. As a method of measurement, the difference between the three groups was analyzed using repeated ANOVA. Results : As a result of analyzing the effects of squat, bracing, and aerobic exercise for 6 weeks, all values of FVC, FEV₁, FEV₁/FVC % were increased from 0 weeks to 6 weeks except FEV₁/FVC %. There was no significant difference in FVC from week 3 to week 6. In the squat, bracing, and aerobic exercise, the changes in spirometry showed that the FVC, FEV₁, and FEV₁/FVC % values in bracing exercise were significantly increased with time than before exercise. As a result of analyzing the changes in the spirometry of squat, bracing, and aerobic exercise, the FVC, FEV₁, FEV₁/FVC % values in the squat exercise showed statistically significant difference according to the period, but the lowest increase among the three groups. Conclusion : In conclusion, aerobic, bracing and squat exercises all had a significant impact on improving lung function. Therefore, even without aerobic exercise, squat or bracing exercise alone can be expected to improve lung function.

• Journal of International Academy of Physical Therapy Research
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• v.6 no.2
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• pp.878-883
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• 2015

The purpose of this study compared the ability of feedback breathing training (FBT) and balloon blowing training to enhance the breathing of elderly people. The subjects were randomly and evenly divided into a feedback breathing training group (FBTG) and a balloon blowing training group (BBTG). Each group trained 3 times a week for 4 weeks, with the training suspended during the last 2 weeks. Pulmonary function measurements were obtained before the test and 2, 4 and 6 weeks after the test: forced vital capacity (FVC), forced expiratory volume at one second (FEV1), FEV1/FVC, peak expiratory flow (PEF) and vital capacity (VC). A repeated-measures ANOVA was conducted for the significance test. The FBT resulted in a significant increase in the FVC, FEV1/FVC, PEF, and VC of the elderly smokers after 4 weeks and a significant decrease in the FVC, FEV1/FVC, and PEF after 6 weeks. The BBT resulted in a significant increase in the FVC, FEV1, FEV1/FVC, PEF, and VC of the elderly smokers after 4 weeks and a significant decrease in the FVC, FEV1/FVC, and PEF after 6 weeks. In conclusion, An at home breathing rehabilitation program, in addition to balloon blowing, could increase the breathing performance of elderly people.

• Tuberculosis and Respiratory Diseases
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• v.87 no.2
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• pp.155-164
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• 2024

Background: Exercise capacity is associated with lung function decline in chronic obstructive pulmonary disease (COPD) patients, but a discrepancy between exercise capacity and airflow limitation exists. This study aimed to explore factors contributing to this discrepancy in COPD patients. Methods: Data for this prospective study were obtained from the Korean COPD Subgroup Study. The exercise capacity and airflow limitation were assessed using the 6-minute walk distance (6-MWD; m) and forced expiratory volume in 1 second (FEV₁). Participants were divided into four groups: FEV₁ >50%+6-MWD >350, FEV₁ >50%+6-MWD ≤350, FEV₁ ≤50%+6-MWD >350, and FEV₁ ≤50%+6-MWD ≤350 and their clinical characteristics were compared. Results: A total of 883 patients (male:female, 822:61; mean age, 68.3±7.97 years) were enrolled. Among 591 patients with FEV₁ >50%, 242 were in the 6-MWD ≤350 group, and among 292 patients with FEV₁ ≤50%, 185 were in the 6-MWD >350 group. The multiple regression analyses revealed that male sex (odds ratio [OR], 8.779; 95% confidence interval [CI], 1.539 to 50.087; p=0.014), current smoking status (OR, 0.355; 95% CI, 0.178 to 0.709; p=0.003), and hemoglobin levels (OR, 1.332; 95% CI, 1.077 to 1.648; p=0.008) were significantly associated with discrepancies in exercise capacity and airflow limitation in patients with FEV₁ >50%. Meanwhile, in patients with FEV₁ ≤50%, diffusion capacity of carbon monoxide (OR, 0.945; 95% CI, 0.912 to 0.979; p=0.002) was significantly associated with discrepancies between exercise capacity and airflow limitation. Conclusion: The exercise capacity of COPD patients may be influenced by factors other than airflow limitation, so these aspects should be considered when assessing and treating patients.

• Journal of Korean Public Health Nursing
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• v.28 no.1
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• pp.22-31
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• 2014

Purpose: The purpose of this study was to examine the impact of body mass index (BMI) and waist circumference (WC) for pulmonary function in normal-weight and obese women. Methods: Data from women aged ${\geq}40$ years were obtained from the 2011 Korean National Health and Nutrition Examination Survey. Obesity was measured by BMI and WC and pulmonary function was measured by forced vital capacity (FVC), forced expiratory volume in 1 second ($FEV_1$), and a ratio between forced expiratory volume in 1 second ($FEV_1$/FVC). Multiple linear regression analysis was performed for assessment of the association between FVC, $FEV_1$, $FEV_1$/FVC and obesity variables. Results: BMI showed positive association with FVC, $FEV_1$, $FEV_1$/FVC, and WC showed positive association with $FEV_1$ and $FEV_1$/FVC in normal-weight women. BMI and WC showed negative association with FVC, $FEV_1$ in obese women. A 1 unit increase in BMI showed an association with a 25-mL reduction in FVC and a 19-mL reduction in $FEV_1$. A 1-cm increase in WC showed an association with a 6-mL reduction in FVC and a 4-mL reduction in $FEV_1$. Conclusions: BMI and WC showed negative association with pulmonary function in obese adult women. Therefore, obese women with reduced pulmonary function should be encouraged to lose weight for improvement of their pulmonary function.

• The Korean Journal of Physiology
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• v.11 no.2
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• pp.45-50
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• 1977

The maximum voluntary ventilation (MVV) is one of the most widely used pulmonary function test, but its measuring method was very difficult and unreliable. However, it is need to get more easy and simple measuring method of MVV. Therefore, this study was attempted to get more easy and simple measuring method of MVV by means of the forced expiratory volume $(FEV_{T})$. The young and healthy 1,000 Korean students(592 male and 408 female) were cheesed for this purpose and whose ages were from 8 to 20 years. A spirometer (9L, Collins Co.) was used for the MVV and FEV, and they were measured 3 times at standing position, and the highest value was used. In the measurements, the subjects for MVV were asked for the breath as fast and deeply as possible for 12 seconds, and for FEV were asked for the rapid and forceful exhalation after a maximal inhalation (forced expiratory curve). In the FEV measurements toward the end of the expiration, the subjects were exhaused to continue the effort until no further gas was expired. During these measurements, the investigator stood by the subject to give a constant encouragement. FEV were calculated in the volume exhaled during the one-half $(FEV_{0{\cdot}5,}\;ml)$, the first second $(FEV_{1{\cdot}0,}\;ml)$ and the percentage of the total vital capacity exhaled during the one-half second $(FEV_{0{\cdot}5,}\;%)$. The results are summarized as follows: 1) The values of MVV were increased linearly with ages until 20 in both sexes. The values of male at the age of 20 was $168.2{\pm}2.5L/min$, and female at the age of 17 was $112.3{\pm}3.0L/min$, respectively. 2) The values of FEV (ml) were increased linearly with ages until 20 in both sexes. The values of $FEV_{0{\cdot}5}$ were $2,797{\pm}65.7ml$ in the male of 20 years and were $2,088{\pm}54.6ml$ in the female of 17 years, and of $FEV_{1{\cdot}0$ were $4,119{\pm}68.2ml$ in the male of 20 years and were $2,897{\pm}65.9ml$ in the female of 17 years, respectively. 3) The correlation coefficients between MVV and $FEV_{0{\cdot}5}\;or\;FEV_{1{\cdot}0$ (ml) were 0.82 or 0.85 in the male, and 0.77 or 0.79 in the female, respectively. 4) The prediction formulae for MVV to be derived from above results were: For male: MVV (L/min) =7.19+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=11.25+$0.04{\times}FEV_{1\cdot0}(ml)$ For female: MVV (L/min)=16.03+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=9.47+$0.03{\times}FEV_{1\cdot0}(ml)$.

• Journal of Korean Biological Nursing Science
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• v.20 no.4
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• pp.214-220
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• 2018

Purpose: This study aimed to investigate the effect of smoking duration, smoked cigarettes per day and smoking cessation period on pulmonary function among ex-smokers: based on the 6th Korea National Health and Nutrition Examination Survey (KNHANES). Methods: This study was analyzed using the 6th KNHANES data. Pulmonary function tests were performed on a total of 4,214 adults (> 40 years old). A total of 770 adults ex-smokers were eligible for inclusion in the final analysis. Forced vital capacity (FVC), forced expiratory volume in one second ($FEV_1$) and $FEV_1/FEV$ were measured to evaluate pulmonary function. Results: This study showed that there were significant differences in both $FEV_1$ and FVC values based on gender, age and height, among ex-smokers. $FEV_1/FVC$ significantly differed by age, height and the smoking duration prior to smoking cessation. Multiple regression analysis revealed that, $FEV_1/FVC$ accounted for 26.0% of the variance by age, height and smoking duration. There was a difference in the mean value of $FEV_1/FVC$ with or without smoking for more than 10 years. Conclusion: This study's findings show that smoking for over 10 years in an ex-smoker can lead to problems with the respiratory system. The long-term cigarette has progressive ill effects on the respiratory system.

• Allergy, Asthma & Immunology Research
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• v.10 no.6
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• pp.614-627
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• 2018

Purpose: Asthma is a heterogeneous disease that responds to medications to varying degrees. Cluster analyses have identified several phenotypes and variables related to fixed airway obstruction; however, few longitudinal studies of lung function have been performed on adult asthmatics. We investigated clinical, demographic, and inflammatory factors related to persistent airflow limitation based on lung function trajectories over 1 year. Methods: Serial post-bronchodilator forced expiratory volume (FEV) 1% values were obtained from 1,679 asthmatics who were followed up every 3 months for 1 year. First, a hierarchical cluster analysis was performed using Ward's method to generate a dendrogram for the optimum number of clusters using the complete post-FEV1 sets from 448 subjects. Then, a trajectory cluster analysis of serial post-FEV1 sets was performed using the k-means clustering for the longitudinal data trajectory method. Next, trajectory clustering for the serial post-FEV1 sets of a total of 1,679 asthmatics was performed after imputation of missing post-FEV1 values using regression methods. Results: Trajectories 1 and 2 were associated with normal lung function during the study period, and trajectory 3 was associated with a reversal to normal of the moderately decreased baseline FEV1 within 3 months. Trajectories 4 and 5 were associated with severe asthma with a marked reduction in baseline FEV1. However, the FEV1 associated with trajectory 4 was increased at 3 months, whereas the FEV1 associated with trajectory 5 was persistently disturbed over 1 year. Compared with trajectory 4, trajectory 5 was associated with older asthmatics with less atopy, a lower immunoglobulin E (IgE) level, sputum neutrophilia and higher dosages of oral steroids. In contrast, trajectory 4 was associated with higher sputum and blood eosinophil counts and more frequent exacerbations. Conclusions: Trajectory clustering analysis of FEV1 identified 5 distinct types, representing well-preserved to severely decreased FEV1. Persistent airflow obstruction may be related to non-atopy, a low IgE level, and older age accompanied by neutrophilic inflammation and low baseline FEV1 levels.

• The Journal of Korean Physical Therapy
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• v.32 no.6
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• pp.383-387
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• 2020

Purpose: The purpose of the present study was to investigate the effects of a simultaneous dual-task and horse-riding simulator (HRS) training regime on pulmonary function and flexibility. Methods: Sixteen subjects were recruited and randomly allocated to two groups: a dual-task (DT) (n=8) or a single-task (ST) (n=8) training group. Flexibility and pulmonary function were assessed before and after HRS training. Both groups underwent HRS training for 4 weeks, 3 times/week in 15-minute training sessions. The ST group underwent HRS training and the DT group underwent dual-task HRS training, which consisted of throwing and catching a ball and ring catching while HRS training. Results: Training significantly increased flexibility and FVC (forced vital capacity) and FEV1 (forced expiratory volume in 1 second) in both groups (p<0.05), but FEV1/FVC and PEF (peak expiratory flow) were not significantly different after training in both groups (p>0.05). After the training, flexibility and FVC in the DT group were significantly greater than in the ST group (p<0.05), but FEV1, FEV1/FVC, and PEF were not significantly different (p>0.05). Conclusion: Simultaneous dual-task and HRS motor training improved flexibility, FVC, and FEV1, and our comparative analysis suggests that dual-task HRS training improved flexibility and FVC more than single-task training.

• Journal of the Korean Society of Physical Medicine
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• v.9 no.3
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• pp.307-314
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• 2014

PURPOSE: The purpose of this study was to investigate the effects of high intensity intermittent training on cardiopulmonary capacity in canoe and kayak paddlers. METHODS: A total of 16 canoe and kayak paddlers were participated in this study. Experimental group(n=8) was performed high-intensity intermittent training and control group(n=8) was moderate intensity training. All subjects performed a treadmill test in order to compare the difference before and after the intervention. Finishing the test, all subjects were measured to their heart rate(HR), forced vital capacity(FVC), forced expiratory volume in one second (FEV1) and forced expiratory ratio(FEV1/FVC). Recovery of heart rate(RHR) was calculated using the HR. HR and pulmonary flow values was measured before and during the intervention period per 2, 4, 6 and 8 weeks. To compare the differences over time between experimental group and the control group, used(time${\times}$group) two-way repeated measures ANOVA. One-way repeated ANOVA was performed to determine where differences over time within-group. RESULTS: One-way repeated ANOVA revealed a significant difference in the experimental and control group. In experimental group, %RHR3min and FEV1 were significantly increased after 4 weeks(p<.05). Also, %RHR1min, FVC and FEV1/FVC were significantly increased after 6 weeks(p<.05). In control group, %RHR1min, %RHR3min, FVC, FEV1 and FEV1/FVC were significantly increased after 6 weeks(p<.05). CONCLUSION: Not only moderate training but also high-intensity intermittent training contributes to cardiopulmonary capacity in canoe and kayak paddlers. Although high-intensity intermittent training is very short time, the training has high degree of efficiency. Therefore, developed this training in the future, it will be better to improve the cardiopulmonary capacity for athletes and healthy people.