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검색결과 24,784건 처리시간 0.047초

Theoretical Investigation of the Triphosphate Forms of Azidothymidine and Thymidine

  • Arissawa, Marcia;Felcman, Judith;Herrera, Juan Omar Machucca
    • BMB Reports
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    • 제36권3호
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    • pp.243-250
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    • 2003
  • In this paper we investigate (using AM1 semi-empirical as well as HF methods at the STO-3G, 3-21G, 6-31G, 6-$31G^*$ and 6-31+$G^{**}$ level) the conformations, geometrical parameters, Mulliken charges, and solvation effects of the triphosphate form of AZT (AZTTP), as well as the thymidine nucleotide (dTTP) structure. Our calculated geometrical parameters and Mulliken charges, with and without solvation effects, are correlated with recent experimental results.

Evaluation of DoP-CPD Classification Technique and Multi Looking Effects for RADARSAT-2 Images

  • Lee, Kyung-Yup;Oh, Yi-Sok;Kim, Youn-Soo
    • 대한원격탐사학회지
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    • 제28권3호
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    • pp.329-336
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    • 2012
  • This paper give further assessment on the original DoP-CPD classification scheme. This paper provides some additional comparative study on the DoP-CPD with H/A/alpha classifier in terms of multi look effects and classification performances. The statistics and multi looking effects of the DoP and CPD were analyzed with measured polarimetric SAR data. DoP-CPD is less sensitive to the number of averaging pixels than the entropy-alpha technique. A DoP-CPD diagram with appropriate boundaries between six different classes was then developed based on the data analysis. A polarimetric SAR image DoP-CPD classification technique is verified with C-band polarimetric RADARSAT-2 images.

해상가두리 어류양식업의 지역별 어종별 생산성 분석 (Productivity Analysis by Region and Species of Fish Cage-culture)

  • 김수현;김대영
    • 수산경영론집
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    • 제52권3호
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    • pp.27-38
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    • 2021
  • This study is aimed to figure out the productivity and variability of cage-aquaculture changes. According to the analysis, the productivity of major fish species has been increasing, except mullet. Although the regional productivity has decreased in the last two years, it has been on the rise considering as a whole. Gyeongsangnam-do showed the highest level of productivity by region. Productivity by species was also higher than other regions in the cases of rock fish, mullet and sea bream followed by productivity of Chungcheongnam-do. The production of marine cage-culture in Jeollanam-do is the second largest in Korea in value/weight while its productivity is lower than that of Chungcheongnam-do. When it comes to comparison by region, Gyeongsangnam-do shows the lowest productivity variation. And Jeollanam-do shows the second-lowest variation in productivity that is only about half of that of Chungcheongnam-do province. Thus, it is found that Jeollanam-do region has an advantage in management stability while its productivity is low. On the other hand, productivity by species was also analyzed. Gyeongsangnam-do has the highest productivity by species for rock fish, mullet and sea bream whereas rock bream productivity is the highest in Jeollanam-do. Therefore, it probably needs to reflect these results when choosing regional-focused incubation fish species.

발효기 하드웨어 변환을 이용한 용존산소 제어 (Feedback Control of Dissolved Oxygen with Hardware Modification of Fermenter)

  • 이중헌;이인영;박영훈
    • KSBB Journal
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    • 제15권3호
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    • pp.280-284
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    • 2000
  • The simple imcroprocessor device was provided for the control of dissolved oxygen(DO) level. The DO analog signal output from fementer was used as a measurement variable and the agitation speed of fermenter was used as a manipulatio variable. Agitation speed was manipulated to maintain DO level above 10% of saturation condition during cell growth period with microprocessor. Since the experimental resultsshowed that the DO level was maintained above 10% and agitation speed was inverse proportional to DO level ithis simple control device can be used for the DO control of fermenter.

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Continuous Stable production of won Willerand Factor Monoclonal Antibody in Spin Filter Bioreactor with Bleeding Technology

  • Yun, Joung-Won;Lee, Soo-Young;Park, Byung-Wook;Han-Kyu oh;Kim, Se-Ho;Byum, Tea-Ho;Park, Soung-yong
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제5권2호
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    • pp.130-135
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    • 2000
  • The characteristics of two different modes of perfusion culture, intermittent and continuous bleedings, were investigated by culturing the hybridoma cells producing von Willebrand Factor (vWF) monoclonal antibody (McAb) in a 15 L bioreactor without clogging the filter. Both culture methods exhibited similar profiles of cell density and metabolite concentrations during the culture period at the cell concentration of around 1${\times}$107 cells/mL. When the perfusion rate was increased, the intermittrnt bleeding culture showed problems of ammonia accumulation and decrease of cell viability. The continuous bleeding culture in terms of nutrient consumption and metabolite production kinetics. But the analysis of specific oxygen consumption rate showed that the specific oxygen consumption rate of intermittent bleeding culture was similar to that of exponential growth phase. The continuous bleeding culture showed higher specific oxygen consumption rate of intermittent bleeding culture. finally we proved the possibility of long-term operation of continuous bleeding culture and produced approximately 40 g of vWF McAb in a 15L bioreactor after one-month operation.

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경기도 북부지역 아파트의 지하주차장 실내공기질 변동 특성 (The Characteristics of Indoor Air Quality Variation in Underground Parking Lots of Apartments located in Northern Gyeonggi Province)

  • 박현구;정연훈;김병록;김진길;신형순;이상수;오조교
    • 한국환경보건학회지
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    • 제44권3호
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    • pp.250-258
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    • 2018
  • Objectives: The study examined indoor air quality during daytime and commute times in underground parking lots in five apartments located in northern Gyeonggi province. Methods: This study examined the temporal characteristics of $PM_{10}$, $CO_2$, CO, HCHO and VOCs in the indoor air quality of the underground parking lots in five apartments. Results: $PM_{10}$ concentration in daytime were ranged from 37.4 to $69.9{\mu}g/m^3$ which complied with the indoor air quality maintenance standard ($200{\mu}g/m^3$) and Gyeonggi province ordinance standard ($180{\mu}g/m^3$). However $PM_{10}$ concentrations in commuting time were in range of $447.3{\sim}944.0{\mu}g/m^3$ that exceeded for both criteria. The $CO_2$, CO and HCHO concentrations complied with the standard. The VOCs indicated high tendency in the order of toluene, xylene, ethylbenzene and benzene. This tendency was more apparent in commuting time than daytime. Conclusion: All indoor parking lots of five apartments were equipped with ventilators. However the most apartment residents did not operate blowers to save electricity and the lack of interest for indoor air quality. In order to improve the indoor air quality of underground parking lots in apartment, operating ventilation system during commuting time is recommended.

경기북부지역 먹는 물 중 브롬이온 및 브롬산염의 분포특성에 관한 연구 (A Study on the Distribution Characteristics of Bromide and Bromate in Drinking Water in Northern Gyeonggi Area)

  • 정종필;최시림;류형렬;박경수;송희일;이현진;조미현;오조교;윤미혜
    • 한국환경보건학회지
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    • 제44권3호
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    • pp.244-249
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    • 2018
  • Objectives: The purpose of this study was the investigation of bromide and bromate in drinking water of water supply plants, mineral springs and small water supply system located in northern area of Gyeonggi province. Methods: Analytical method was based on EPA 326.0 to use Postcolumn reaction (PCR). The instrument was 887 professional UV/VIS detector IC manufactured in Metrohm. Results: Bromate was detected at $0.5{\sim}2.4{\mu}g/L$ in tap water from 5 water supply plants. These plants were used as disinfection method for sodium hypochlorite and on-site chlorine that causes generate bromate as a by products even if not used ozone. Conclusions: The bromate was detected up to $2.5{\mu}g/Lin$ drinking water in northern Gyeonggi area that showed within $10{\mu}g/L$ for standard of tap water. However, the continuous monitoring of bromate is necessary in drinking water.

최근 4년간(2005~2008) 울릉도와 독도의 강수 및 기온 특성 (Characteristics of Precipitation and Temperature at Ulleung-do and Dok-do, Korea for Recent Four Years(2005~2008))

  • 이영곤;김백조;박길운;안보영
    • 한국환경과학회지
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    • 제19권9호
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    • pp.1109-1118
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    • 2010
  • Characteristics of precipitation and temperature in Ulleung-do and Dok-do were analyzed with hourly accumulated precipitation and mean temperature data obtained from Automatic Weather System(AWS) for latest four years(2005~2008). In Ulleung-do, total annual mean precipitation for this period is 1,574.4 mm, which shows larger amount than 1434.2 mm of whole Korean peninsula for latest 10 years(1999~2008) and 1,236.2 mm at Ulleung-do on common years(1971~2000), shows that the trend of precipitation gradually increases during the recent years. This amount is also 1.4 times larger than the total annual mean precipitation of 660.1 mm in Dok-do. Mean precipitation intensity(mm $h^{-1}$) at each time of a day in each month at Ulleung-do represents that the maximum values larger than $3.0\;mm\;h^{-1}$ were shown in May and on 0200 LST, whereas these were found in August and 0700 LST with $3.1\;mm\;h^{-1}$ in Dok-do. The difference of the precipitation amount and its intensity between Uleung-do and Dok-do is explained by the topological effect came from each covering area, and this fact is also identified from similar comparison of the precipitation characteristics for the islands in West Sea. The annual mean temperature of $14.0^{\circ}C$ in Dok-do is $1.2^{\circ}C$ higher than that of $12.8^{\circ}C$ in Ulleung-do. Trends of monthly mean temperature in both islands are shown to increase for the observed period.

2019년도 국내 골재 수급 분석 (I) (Analysis of 2019 Domestic Aggregate Production in Korea (I))

  • 홍세선;이진영
    • 자원환경지질
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    • 제53권6호
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    • pp.755-769
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    • 2020
  • 2019년에 국내에서 채취된 골재에 대하여 광역시도별로 채취현황분석을 실시하였다. 2019년에 전국에서 채취된 골재는 약 1억3천4백만 ㎥로 이 중 모래는 약 4천1백만 ㎥, 자갈은 약 9천3백만 ㎥가 채취되었다. 골재원별로는 선별 파쇄골재(50.3%)가 가장 많이 채취되었으며, 산림골재(41.4%), 육상골재(3.3%), 바다골재(1.7%), 선별세척(1.7%), 하천 골재(0.7%) 순이다. 이는 선별파쇄골재와 산림골재가 국내 골재채취의 주생산지임을 말해준다. 권역별로 보면 경기도가 국내 골재 채취의 약 30%를 점하며, 그 다음으로 경상남도, 충청북도, 강원도, 경상북도, 충청남도의 순이다. 주로 채취되는 골재는 지역적으로 차이가 있다. 경기도는 선별파쇄골재가 가장 많이 채취되며, 경상남도는 산림골재가 가장 많이 채취된다. 또한 육상골재는 경상북도와 강원도에서 채취가 가장 많이 되는 등 지역에 따라 채취가 용이한 골재의 종류가 다르다. 2019년도 골재채취의 특징은 하천골재와 바다골재의 채취가 현저히 줄어든 반면 선별파쇄와 산림골재의 채취가 증가하여 전체 골재채취물량의 약 90%가 넘는다는 것이다. 따라서 골재자원의 향후 수급에 있어 선별파쇄와 산림골재에 우선적인 정책방향이 있어야 할 것으로 판단된다.

WeDo 로봇 활용 초등 메이커 교육 프로그램 개발 (Development of Elementary Maker Education Program using WeDo Robot)

  • 권순환;박정호
    • 한국정보교육학회:학술대회논문집
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    • 한국정보교육학회 2021년도 학술논문집
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    • pp.335-340
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    • 2021
  • 본 연구는 농어촌 초등학교 저학년을 대상으로 로봇과 SW교육을 위한 메이커 교육 프로그램 환경 조성, 메이커교육 프로그램 개발 및 적용 연구를 수행하였다. 선행 메이커교육 모델을 기초로 초등학교 저학년 수준에 맞는 OMCSI 모형은 개발하였으며, 이를 기초로 5종의 WeDo 활용 초등 메이커 교육 프로그램을 개발하였다. 2020년 4월 1일 ~ 2020년 10월 30일까지 경상남도 대합초등학교의 2학년 10명을 대상으로 WeDo로봇 2.0을 활용한 초등 메이커 교육 프로그램을 적용한 결과는 다음과 같다. 컴퓨팅사고력의 분석능력에서 평균이 3.40점 올랐으며(t=-2.378, p=0.034), 설계능력에서도 평균이 3.30점 올랐다.(t=-2.329, p=0.040). 그리고 구현능력에서도 평균이 3.40점(t=-2.458, p=0.038)올랐다. 마지막으로 추론능력에서는 3.70점(t=-2.449, p=0.037)로 올랐다. 즉, 컴퓨팅 사고력 4개의 하위요소 모두가 유의확률 0.04이하로 사전사후 컴퓨팅 사고력의 점수 간에는 통계적인 유의미한 차이를 나타냈다. 따라서 WeDo 로봇을 활용한 초등 메이커 교육 프로그램'이 학생들의 컴퓨팅 사고력 향상에 매우 효과적으로 작용했다고 할 수 있다

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