• Journal of Physiology & Pathology in Korean Medicine
• /
• v.31 no.2
• /
• pp.111-117
• /
• 2017

The anti-cancer effects of Astragalus membranaceus (AM) and Adenophora triphylla var. japonica (AT) have been described. Each of their effects mainly focused on the immunopotentiating and apoptosis inducing-ability in several cancer cell lines. Although the combination of AM and AT is occasionally used in Chinese medicine to treat lung cancers, their synergistic effect has not been proved yet. This study was designed to verify whether AM combined with AT exhibits a synergistic anti-cancer effect in H1299 human lung carcinoma cells. The ethanol extracts of AM (EAM) and AT (EAT) showed only slight cytotoxicity in H1299 cells when treated alone. However, the combination of EAM and EAT markedly suppressed the cell growth measured by MTT assay and trypan blue counting assay. In addition, co-treatment of EAM with EAT significantly reduced the colony-forming ability compared with single treatment of EAM or EAT in H1299 cells. We demonstrated that the synergistic effect of AM and AT was related with apoptosis induction proved by an accumulation of chromatin condensation, annexin V-positive cells, sub-G1 phase population, and cleaved-PARP expression, which were not observed by single treatment of EAM or EAT. In conclusion, the combination of EAM and EAT exhibited superior anti-cancer activity in H1299 cells than single treatment of EAM or EAT. We suggest that EAM combined with EAT might be a novel therapeutic option for lung cancer patients, and provide a reference for the development of more effective combination of Chinese herbs to treat lung cancer.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
• /
• v.10 no.1
• /
• pp.111-116
• /
• 2017

We propose the compact circular polarized antenna. The radiation elements of the proposed antenna is designed using FR4 substrate with the size of $25mm{\times}3.2mm{\times}5mm$ and stand on four corners of the feed network substrate. The feeder network is designed on FR4 substrate with the size of $40mm{\times}40mm{\times}0.8mm$ and has four oupt signals with same magnitude and $90^{\circ}$ phase difference. The input impedances of the designed radiation elements and the output impedances of the feeder network are $100{\Omega}$. The designed antenna has the dimension of $40mm{\times}40mm{\times}5.8mm$ and the operated frequency band of 1.559 - 1.609 GHz. The fabricated antenna has RHCP radiation pattern and the measured results of axial ratio less than 3.5 dB and radiated gain more than 1.5 dBic. The fabricated antenna can apply to GLONASS and Beiodu systems as well as GPS system.

• Korean Journal of Food Science and Technology
• /
• v.22 no.4
• /
• pp.373-379
• /
• 1990

Lactic acid bacteria(LAB) were isolated from fermenting Kimchi and were cultivated in filter-sterilized Chinese cabbage juice individually or in combination. LAB isolated were Lactobacillus leichimannii, Lac. fermentum, in addition to the already known Leuconostoc mesenteroides, Lac. plantarum, lac. brevis and pediococcus pentosaceus. Lac. leichimannii, Lac. fermentum and Lac. sake, the early lactobacilli, were high in number exceeding $10^4cells/ml$ at 0 time and multiplied up to $10^9cells/ml$ altogether at the 3rd day of kimchi fermentation. When the representative LAB were cultivated singly in Chinese cabbage juice with or without 3.0% NaCl, one strain of Leu. mesenteroides and La. leichmannii were not different in acid producing ability while the other strain of Leu. mesenteroides and Lac. fermentum Lac. plantarum, produced less acid when NaCl was present. When the bacteria in combination were cultivated in Chinese cabbage juice with 3.0% NaCl, the presence of Leu. mesenteroides was essential to eliminate the lag phase in acid production with higher amounts of acid produced than without. The total number of lactobacilli in the mixture of kimchi ingredients was about $2.9{\times}10^4 cells/ml$ while the number of Lac. plantarum was 7.3 cells/ml. The number of Lac. plantarum in individual ingredients were normally in the range between $0.0{\sim}240cells/g$ except garlic sold in ready-to-use form with $9.0{\times}10^3 cells/g$.

• Journal of Conservation Science
• /
• v.30 no.2
• /
• pp.111-122
• /
• 2014

In Bongseon-ri site, the central type and the local type of the Baekje tombs co-exist together. Many swords with ring pommel which to regional leaders in Seocheon the Beekje government granted are excavated from these tombs. These represent that the regional leaders were controlled by the Baekje government gradually. Four swords with ring pommel and one simple sword are investigated metallurgically and we seek what swords have a function of weapon or what sword produce for grave goods. The simple sword is made by solid carburizing technology and quenching of heat treatment so it's possibly used as a weapon. In contrast, four swords with ring pommel has little chance of weapon because the blade of swords consists of microstructure that have low hardness and the back of swords don't have microstructure can absorb the shock. The most identical characteristic of the simple sword and swords with ring pommel is that they are possible to classify clearly into practical/non-practical tools. Additionally, according to non-metallic inclusion analysis result of these swords, w$\ddot{u}$stite and glass phase are found together. Thus, it is able to say that reduction method in low temperature is applied during smelting process.

• Journal of the Korean Ceramic Society
• /
• v.40 no.2
• /
• pp.172-177
• /
• 2003

Effect of glass addition on the low-temperature sintering and microwave dielectric properties of $BaTi_4O_9$-based ceramics were studied to develop the materials for the functional substrate of low-temperature co-fired ceramics. When 10 wt% of glass was added, sufficient densification was obtained and the relative density more than 98% was reached at the sintering temperature of$875{\circ}C$. The microwave dielectric properties were k=32, Q＊f=9000 GHz, ${ au}_f$=10 ppm/${\circ}C$. As the amount of glass increased, phase decompositions from $BaTi_4O_9;to;BaTi_5O_{11};and;Ba_4Ti_{13}O_{30}$ was observed.

• The Korean Journal of Community Living Science
• /
• v.18 no.2
• /
• pp.323-334
• /
• 2007

This study was made to analyze the condition and the needs of nutrition education considering the different stage of nutrition education recognized by the dietitian in industrial area. 165 female dietitian were surveyed by questionnaire and they were divided into 4 groups according to the different recognition stages of nutrition education: Pre-contemplation(PC) 4.8%, Contemplation(CO) 46.7%, Preparation(PR) 22.4%, Action & Maintenance phase(AM) 26.1%. For statistical analysis, SAS(Ver.8.1. for Window) was used to find out the distribution related with nutrition education and to calculate the scores of mean and standard deviation. General characteristics of the subjects are about 20 years old(71.5%), single(69.7%), careers over 5 years(40%) and university graduates(73.9%). The number of meals(p<0.05) and the employment status(p<0.05) were significantly different according to the recognized stage of nutrition education. The practice of nutrition education was different depending on the dietitian in the industry. Many of the factory dietitian were in pre-contemplation stage(87.5%), however, those in the office and service area were more in Action & Maintenance stage(27.9%). In the industrial area, just 26.1% of dietitian operated the nutrition education and most did not due to the work overload and insufficient support of staff(73.3%). The frequency for the most effective nutrition education was once a month(61.2%). The contents for desirable nutrition education were in the order of 'eating habits'(36.1%), 'relation with the daily life'(23.5%), 'food hygiene' (21.7%), 'nutrition knowledge'(9.7%), and 'disease prevention'(9%). In operating nutrition education, dietitian had concerns about 'insufficient support of staff', 'shortage of teaching materials' and 'lack of time'. And, the dietitian who were with lower recognition stage of nutrition education(P<0.05) concerned more about the insufficient educational contents. In conclusion, dietitian in the industry highly recognized the need of nutrition education, but it was so difficult to practice. For more programs and various materials should be developed, and the staff's perception, the view of dietitian and the meal service should be changed, too. For the health improvement of industrial workers, it would be necessary to proclaim the importance of nutrition education nationwide.

• Journal of the Korean Crystal Growth and Crystal Technology
• /
• v.25 no.2
• /
• pp.62-67
• /
• 2015

The carbon microspheres of a core-shell type were grown by the method of mixed-source hydride vapor phase epitaxy (HVPE). The surface and the cross section of the carbon microsphere grown by a new method were observed by scanning electron microscope (SEM). The characteristics of the carbon microsphere were investigated by X-ray photoelectron spectroscopy (XPS) and a high resolution-transmission electron microscope (HR-TEM). From these measurements, the diameters of carbon sphere were about few hundred micrometers. Furthermore, we show that the carbon microsphere of the core-shell type by mixed-source HVPE method can be grown successfully with the larger size than those of the existing one. This mixed-source HVPE method is proposed a new method for making of carbon microsphere.

• 대한공업교육학회지
• /
• v.33 no.2
• /
• pp.312-324
• /
• 2008

To improve the newly designed HKS(hinge kit system) in common refrigerators, it was investigated the new robust methodologies. There were the study of failure modes, mechanisms in the marketplace, and the design parameters of HKS with various improvements using accelerated life testing. Based on the claimed marketplace product returns and 1st ALT reproduction, the fracturing and cracking occur in the housing of the HKS. The missing design parameters of the failed HKS in the design phase of the refrigerator was the housing hinge kit structure. The corrective action plans are the modifications of the housing hinge kit structure from the open supporting to all supporting structure. Based on 2nd ALTs, the fracturing and cracking occur in the torsion shaft. The missing design parameter was the roundness of torsion shaft. After a sequence of ALT testing, the levels of the missing design parameters were setup. The yearly failure rate and B1 life of the redesigned HKS, based on the results of ALT, were over 0.01 percent and 10 years, respectively. The parameter design through the inspection of the failed product, load analysis, and three rounds of ALT, was very effective in the new robust design methodologies of the mechanical system and this method can be applied to other design system.

• Journal of the Korea Institute of Building Construction
• /
• v.10 no.5
• /
• pp.45-54
• /
• 2010

Recently more and more construction projects have become high-rise, complex and intelligent. Accordingly, such projects require an integrated management system for tasks, with a lean approach to construction with work processes for management and productivity. In particular, Construction Information Technology (CIT) fields are concerned with Building Information Modeling (BIM), which represents the process of generating and managing building data during its life cycle. Constructability research has progressed for the project goal which is a cost-time-quality of optimization by integrated construction knowledge and experience. However, the current constructability process has not been performed efficiently, as the existing 2D drawings and papers lack consistent and accurate information, it is difficult to share the contents of work, and the use of information is inefficient. This study proposes that the reformation and enhancement of BIM-based constructability work process can lead to brilliant performance in the framework of the construction phase through achieving collaboration between the design team and the workers at the site.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.36 no.4
• /
• pp.329-336
• /
• 2000

Welding is a important technological method in mechanical engineering. $CO_2$MAG(metal active gas) welding means that metal part in double capstan drum for the inshore and costal vessels are joined by melting(with or without a filler material) or that new material is added to a metal part by melting. The thermal stresses appear due to a non-uniform temperature field, inhomogeneous material properties, external restraint and volume changes during phase transformations. In this study analysis the elasto-plastic thermal stresses distribution of welding part in double capstan drum for the inshore and costal vessels using finite element method (FBM). Therefore it calculates the numerical value that can be applied to the optimum design of welding parts and the shapes. The significant results obtained in this study are summarized as fellows. At early stage of the cooling after welding process, the abrupt thermal stresses gradient has been shown in the vicinity of welding part. In the thermal stresses analysis due to temperature gradient and heat shocking maximum stress was occurred of welding part and stresses were distributed from 54MPa~48MPa.