• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.1079-1082
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• 2005

This paper deals with the algorithm development that inspects defects such as Lens Focus, Focus check, Black Defect, Dark Defect, Dim Defect, Color Defect, and Line Defect, Angle Defect, IrisAgc Defect caused by the process of 2M Class Compact Camera Module (CCM). Domestic market was majorly comprised of VGA(0.3 million pixel) market. But in the middle of year 2004, camera phone with Mega Pixel has appeared, and it is estimated that the camera phone with Mega Pixel will take up to 28% of total phone sales if it is released in the end of year 2004. Since the inspection of finished products is done manually, it is major obstacle in production increment In this paper, to solve these problems, we developed the imaging processing algorithm to inspect the defects in captured image of assembled CCM. The performances of the developed inspection system and we can recognize various types of defect of CCM modules with good accuracy and high speed

• Journal of Animal Science and Technology
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• 제53권5호
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• pp.469-474
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• 2011

본 시험은 충남 아산과 경남 산청에서 논을 이용하여 2006년부터 2008년까지 3년에 걸쳐 수행되었으며, 작부체계는 하계작물 총체 벼와 동계작물 IRG을 이용한 2모작 작부체계를 이용하였다. 시험구의 처리는 N 기준으로 화학비료 시용구(대조구), 우분퇴비150% 및 우분퇴비 200% 시용구로 하였다. 가축분뇨 시용에 따른3년 평균 연간 건물생산성은 아산지역의 경우 우분퇴비 200% 시용구에서 20,347 kg/ha로 가장 높았으며, 화학비료 시용구에서 19,165 kg/ha, 우분퇴비 150% 시용구 18,358 kg/ha 순이였다. 하지만 우분퇴비 200%구와 화학비료 처리구간에 건물생산성의 유의적인 차이가 나지 않았으며, 우분퇴비 150%구에서는 유의적인 감소를 보였다(p<0.05). 산청지역의 건물생산성은 화학비료 시용구에서 20,531 kg/ha, 우분퇴비 200% 시용구의 18,048 kg/ha, 우분퇴비 150% 시용구의 16,647 kg/ha로 유의적인 감소를 보였다(p<0.05). 산청지역에서 IRG의 건물생산성은 화학비료구, 우분퇴비 200%, 우분퇴비 150% 시험구 순으로 높았으나, 화학비료구와 우분퇴비 200% 시용구간의 유의적인 차이는 인정되지 않았다(p<0.05). 또한 아산지역은 처리구간의 건물수량에 차이는 있었으나 유의적인 차이는 나타나지 않았다. 총체 벼의 건물생산성은 아산지역의 경우 화학비료 시용구에서 우분퇴비 200% 시용구와 유의적이 차이가 없었고, 우분퇴비 150% 시용구 보다는 유의적으로 높게 나타났다(p<0.05). 산청지역의 경우 화학비료 시용구에서 우분퇴비 150% 및 200% 시용구에 비해 유의적으로 높게 나타났다(p<0.05). 가축분뇨 시용에 따른 총체 벼의 3년 평균 초장 및 경수는 처리구간 유의적인 차이가 없었으며, 벼의 등숙률은 아산과 산청 모두에서 화학비료구가 우분퇴비 150% 및 200% 시험구에 비해 유의적으로 높게 나타났다(p<0.05). 혹명나방에 의한 피해는 처리구간에 큰 차이를 나타내지 않았으나, 잎집무늬마름병 피해는 산청지역의 경우 우분퇴비 시용구가 화학비료 시용구에 비해 높게 나타났다. 가축분뇨에 시용에 따른 사료가치는 IRG의 조단백질은 화학비료구가 우분퇴비 150% 및 200% 시험구에 비해 유의적으로 높게 나타났으나(P<0.05), NDF 및 ADF의 처리구간 유의적인 차이는 없었다. 가축분뇨 시용에 따른 토양의 pH, 토양유기물 함량 및 치환성 양이온 함량은 시험 전 토양에 비해 많이 개선되었으며, 토양 유기물 함량의 경우 시험 전 토양에 비해 가축분뇨 시용구의 유기물 함량이 약 29~44% 증가하였다. 본 연구의 결과 논에서 가축분뇨를 이용하여 IRG과 총체 벼를 재배하면 연간 약 18~20톤의 친환경 조사료를 생산할 수 있어, 논을 친환경 조사료 생산기반으로 활용한다면 조사료 자급률도 높이고 쌀 과잉 생산 문제 해결에도 도움이 될 것으로 생각된다.

• 대한본초학회지
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• 제38권2호
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• pp.17-26
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• 2023

Objectives : A persistent inflammatory response can cause diseases such as fibrosis, cancer, and allergies. This study aimed to investigate the anti-inflammatory activity of Curcumae longae Rhizoma and Cinnamomi Ramulus Mixture (CCM) in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Methods : The total polyphenol and flavonoid contents of CCM were confirmed through an in vitro experiment. Also, radical scavenging activities of 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and Hydroxyl were confirmed. Moreover, ferric reducing antioxidant power (FRAP) activity were confirmed. After, CCM (50, 100, and 200 ㎍/mL) were applied to 0.1 ㎍/mL LPS-stimulated RAW264.7 cells. The levels of nitric oxide (NO) and pro-inflammatory cytokines in the supernatant fraction were determined. Also, the expressions of mitogen-activated protein kinase (MAPK) and nuclear factor-κB (NF-κB) pathways were detected using Western blot. Results : As a result of in vitro experiments, there was an excellent antioxidant activity in CCM-treated cells. In addition, in RAW264.7 cells stimulated with LPS, the increased NO level was inhibited in a concentration-dependent manner by the treatment of CCM. In addition, inflammatory cytokines production were significantly inhibited in a concentration-dependent manner in CCM-treated group. CCM treatment significantly decreased the protein expressions of MAPKs. Moreover, the expressions of NF-κBp65 and cyclooxygenase-2 (COX-2) were significantly decreased when 200 mg/kg of CCM was applied, and phospho-inhibitor of nuclear factor kappa B-α (p-IκBα) and inducible nitric oxide synthase (iNOS) were significantly decreased at all concentrations treated with CCM. Conclusion : Our findings show that CCM exhibited excellent antioxidant activity and exhibited superior anti-inflammatory effect through the MAPKs and NF-κB pathways in LPS-stimulated RAW 264.7 macrophages.

• 한국항공우주학회지
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• 제45권3호
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• pp.241-251
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• 2017

EFD-CFD 워크샵 중 Case3인 RAE Wing A 형상에 대해 전산유체역학 해석을 수행하였다. 해석자로 3개의 상용 CFD 해석 코드(Star-CCM+, Fluent, CFX)와 오픈 소스 CFD 코드(SU2)를 사용하였다. 격자는 상용 격자 생성 코드인 Pointwise를 이용하여 격자의 수에 따라 4가지를 생성하였다. 마하수 0.4, 0.8에서 는 받음각 2도, 마하수 0.9에서 받음각 1도에서 해석하였다. coarse격자부터 fine 격자까지는 압력계수 곡선과 수직력 계수는 비슷한 결과를 보였으나 항력 계수에서는 차이가 있었다. Star-CCM+과 Fluent의 해석에서 차분법의 차수가 높을수록 충격파의 위치를 앞으로 예측하였다. 수렴에 다다르는 계산시간은 Fluent, Star-CCM+, CFX의 순으로 나타났고 SU2는 이에 비해 수렴하는데 많은 시간이 들었다.

• Clinical and Experimental Pediatrics
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• 제59권6호
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• pp.280-284
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• 2016

Cerebral cavernous malformation (CCM) is a vascular malformation characterized by abnormally enlarged capillary cavities without any intervening neural tissue. We report 2 cases of familial CCMs diagnosed with the CCM1 mutation by using a genetic assay. A 5-year-old boy presented with headache, vomiting, and seizure-like movements. Brain magnetic resonance imaging (MRI) revealed multiple CCM lesions in the cerebral hemispheres. Subsequent mutation analysis of his father and other family members revealed c.940_943 del (p.Val314 Asn315delinsThrfsX3) mutations of the CCM1 gene. A 10-month-old boy who presented with seizure-like movements was reported to have had no perinatal event. His aunt was diagnosed with cerebral angioma. Brain and spine MRI revealed multiple angiomas in the cerebral hemisphere and thoracic spinal cord. Mutation analysis of his father was normal, although that of the patient and his mother revealed c.535C>T (p.Arg179X) mutations of the CCM1 gene. Based on these studies, we suggest that when a child with a familial history of CCMs exhibits neurological symptoms, the physician should suspect familial CCMs and consider brain imaging or a genetic assay.

• Mass Spectrometry Letters
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• 제5권3호
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• pp.63-69
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• 2014

In this study, we present a new isotope-coded carbamidomethylation (iCCM)-based quantitative proteomics, as a complementary strategy for conventional isotope labeling strategies, with providing the simplicity, ease of use, and robustness. In iCCM-based quantification, two proteome samples can be separately isotope-labeled by means of covalently reaction of all cysteinyl residues in proteins with iodoacetamide (IAA) and its isotope (IAA-$^{13}C_2$, $D_2$), denoted as CM and iCCM, respectively, leading to a mass shift of all cysteinyl residues to be + 4 Da. To evaluate iCCM-based isotope labeling in proteomic quantification, 6 protein standards (i.e., bovine serum albumin, serotransferrin, lysozyme, beta-lactoglobulin, beta-galactosidase, and alpha-lactalbumin) isotopically labeled with IAA and its isotope, mixed equally, and followed by proteolytic digestion. The resulting CM-/iCCM-labeled peptide mixtures were analyzed using a nLC-ESI-FT orbitrap-MS/MS. From our experimental results, we found that the efficiency of iCCM-based quantification is more superior to that of mTRAQ, as a conventional nonisobaric labeling method, in which both of a number of identified peptides from 6 protein standards and the less quantitative variations in the relative abundance ratios of heavy-/light-labeled corresponding peptide pairs. Finally, we applied the developed iCCM-based quantitative method to lung cancer serum proteome in order to evaluate the potential in biomarker discovery study.

• 한국항공우주학회지
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• 제32권10호
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• pp.46-52
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• 2004

본 논문은 2중으로 다중화된 무인 비행체의 다중화 관리 설계 방법에 대하여 논의한다. CCM(Cross Channel Monitor) 기법의 두 주요 인자, 즉 두 채널간의 편차 허용한도인 문 턱값(threshold) 및 지속시간(persistence count)을 어떻게 설계하여야 하는 가에 관한 문제를 통계학적인 해석을 사용하여 그 해결법을 제시하였다. 또한, 무인 비행체의 생존확률을 증대시킬 수 있는 해석적 다중화 가법에 대한 문제를 칼만 필터링 (Kalman filtering)을 적용하여 접근하였다. 여기서 제시된 방법으로 설계된 CCM 및 칼만 필터링을 이용한 해석적 다중화의 설계 결과들은 XV-15 틸트 로터 비행체에 적용되어, 그 설계의 타당성이 시뮬레이션을 통하여 검증되었다.

• 신재생에너지
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• 제3권1호
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• pp.60-67
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• 2007

Catalyst coated membrane [CCM] type and catalyst coated substrate [CCS] type of membrane electrode assembly [MEA] were manufactured and evaluated their performance. Degradation test were conducted to find the difference of long term stability in two types of MEA and the factor for performance degradation problem occurred. Performance degradation test of single cell in two different types of MEA were carried out when current density was $200mA/cm^{2}$. The degradation test had proceeded for 230 hours and performance degradation was checked by I-V curve and impedance measurement at regular intervals. Also, MEA before/after operation and changes of catalyst layer were characterized by SEM, TEM, and XRD. Maximum power density of CCM type was higher than that of CCS type. Meanwhile, an increase of particle size of catalyst and an increase of impedance resistance after long term operation were observed. In the case of using CCM type MEA, the performance was deteriorated 38% of initial performance. In the case of using CCS type MEA, the performance was deteriorated 43% of initial performance. In consideration of difference of initial performance, performance of CCM type is higher than that of CCS type but both types had similar problems during degradation test.

• 대한조선학회논문집
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• 제51권4호
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• pp.321-327
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• 2014

A wide scope of numerical simulations was performed to predict model-ship resistances by using STAR-CCM+ and OpenFOAM. The numerical results were compared with experimental measurements in towing tank to analyze statistical reliability of the present simulations. Based on the normal distribution of resistance errors in 113 cases of container carriers, tankers and very large crude-oil carriers, the confidence intervals of numerical error were estimated as [-2.64%,+2.32%] and [-1.82%, +1.87%] with 95% confidence in STAR-CCM+ and OpenFOAM, respectively. The resistance errors of liquefied natural gas carriers with single- and twin-skeg were confident in the ranges of [-2.51%,+2.64%] and [-2.29%, +1.46%], respectively. The grid uncertainty of resistance coefficients for KCS was also quantitatively analyzed by using a grid verification procedure. The grid uncertainty of OpenFOAM (5.1%) was larger than 4.4% uncertainty of STAR-CCM+ although OpenFOAM provided statistically more confident results than those of STAR-CCM+. It means that a grid system verified under a specific condition does not automatically lead to statistical reliability in general cases.

• 건축역사연구
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• 제8권1호
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• pp.41-52
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• 1999

This study aims to infer the plan and location of the government office building in Chongju Castle in the Late Yi-dynasty. The conclusion is as follows: 1. The Chongju Castle Map(淸州邑城圖, late in the 18th century, hereinafter referred to CCM) provides the detail arrangement and location of Government Office Building in Chongju Castle. And the road structure and plan of the CCM is almost same with the present time. 2. As compared with CCM and a Chongju-land Registration Map(淸州面地籍原圖, 1913, CRM) to infer the location of the traditional government office building in Chongju Castle, the building locations of Gaek-Sa(客舍) Donghun(東軒)'s region in CCM are almost accordance with today's. But those of Byungyoung(兵營) Group's region are represented by a little error. So the locations of Byungyoung(兵營) Group's region rearranged, moved down to be in accordance with the approach circulation of Main Gate(閉門樓) which is shown in CRM. 3. The records, on the plan of the traditional government office building in Chongju Castle, have proved that the plan of Gaek-Sa was a width of 11 bay and a depth of 2 bay. A width of 3 bay drawn in CCM, the present plan of Donghun is a width of 7 bay and a depth of 4 bay. The main building and especially the double-storied Main Gate($4{\times}3$) of Byungyoung Group are exactly in keeping with the present road structure.