• Title/Summary/Keyword: $CCI_4$

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A Study on the Changes of Advertising Appeals and Consumption Values of Cosmetic Advertisements in Adolescent′s Magazines (청소년잡지에 나타난 화장품광고의 소구유형 및 소비가치의 변화에 관한 연구)

  • 김희숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.26 no.3_4
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    • pp.492-502
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    • 2002
  • The purpose of this study was to investigate the advertising appeals and consumption values expressed on cosmetic advertisements in Adolescent's magazines from 1973 to 2000. The data for longitudinal content analysis were collected from Adolescent's magazine : Junior Joongang(1973.3∼1985.12), Highteen(1986.1∼1994.9), Cci(1994.l0∼2000.12). Collected data was consisted of 542 advertisements. 1. The product categories in cosmetics advertisements, the major were Base Make-up in the past but the number of Color Make-up, Functional Make-up, and Hair-related Products had increased in 1990s. Also, there were more increasing number of imported products than domestics. 2. The trend of appeals showed change according to time and society. Overall, a great many of cosmetic advertisements had emotional approach. Before the middle of the 1980's emotional approach had decreased, and mixed(rational and emotional) approach were dominated in 1990s. 3. The major consumption values in cosmetics advertisements were effective value. Especially, it had increased from 1990s. And esthetic value was dominated in the middle of the 1970s.

Studies on the Physiological Activities of Caragana chamlagu Roots -Effects on the Hyperlipemia, Hyperglycemia and Liver Damage- (골담초근의 생리활성 -고지질, 고혈당 및 간손상에 미치는 영향-)

  • Kim, Hak-Sun;Kim, Il-Hyuk
    • Korean Journal of Pharmacognosy
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    • v.23 no.2
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    • pp.96-105
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    • 1992
  • The studies were attempted to evaluated the therapeutic effects of various fractions(ether, methanol, butanol) of Caragana chamlagu roots on the hyperlipemia induced by feeding the diet containing 1%, cholesterol and 0.5%, cholic acid in rats, and on the hyperglycemia induced by streptozotocin in rats. Also the preventive effects of these fractions were studies on the liver damage in $CCl_4-intoxicated$ rats. The followings were obtained as the results: 1.The butanol fraction was significantly shown to down the serum lipid level in 1%, cholesterol and 0.5%, cholic acid diet-feeding rats and streptozotocin-induced hyperglycemic rats. Cholesterol level in $CCl_4-intoxicated$ rats was reduced in the case of all pre-treated groups. 2.The serum glucose level of streptozotocin-induced hyperglycemic rats was significantly decreased by the administration of various fractions of C. chamlagu roots, and the lipid-peroxidation of pancreas was significantly decreased in the case of administration of these fractions. 3.The activates of s-GOT and s-GPT were decreased by the administration of various fractions, especially in butanol fraction, of C. chamlagu roots in the $CCl_4-intoxicated$ rats. The liver lipid-peroxidation was decreased by administration of 200mg/kg of these fractions in the $CCl_4-intoxicated$ rats. In histological observation, hepatic cellular necrosis and fatty acid deposit were increased remarkably by $CCl_4-intoxication$, but the pretreatment of various fractions of C. chamlagu roots improved the pathological change of parenchymatous cell necrosis and fatty change around centrilobular area of the control.

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Health Risk Assessment of Aldehydes and VOCs in the Activities Space of Young Children -Focused on Child-care Facilities and Indoor Playgrounds- (어린이 주요 활동 공간의 휘발성 유기화합물 노출로 인한 건강 위해성 평가 -보육시설 및 실내놀이터 중심으로-)

  • Yang, Ji-Yeon;Kim, Ho-Hyun;Yang, Su-Hee;Kim, Sun-Duk;Jeon, Jun-Min;Shin, Dong-Chun;Lim, Young-Wook
    • Environmental Analysis Health and Toxicology
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    • v.25 no.1
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    • pp.57-68
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    • 2010
  • This study assessed the lifetime cancer and non-cancer risk of aldehydes and volatile organic compounds exposure of young children at child-care facilities and indoor playgrounds in Korea. The samples were collected at various children's facilities (40 day-care houses, 42 child-care centers, 44 kindergartens, and 42 indoor playgrounds) in summer (Jul~Sep, 2007), winter (Jan~Feb, 2008) and Spring (Mar~Apr, 2008) periods, and analyzed by GC-MS. We estimated the lifetime excess cancer risks (ECRs) of formaldehyde, acetaldehyde, benzene, chloroform, CCI4 and tetrachloroethylene, and the hazard quotients (HQs) of Non-carcinogens (toluene, xylene, benzaldehyde and formaldehyde). Formaldehyde evaluated both cancer and non-cancer risk. The average ECRs of formaldehyde for young children were $1\times10^{-4}{\sim}1\times10^{-5}$ level in all facilities. HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities.

Ensemble Downscaling of Soil Moisture Data Using BMA and ATPRK

  • Youn, Youjeong;Kim, Kwangjin;Chung, Chu-Yong;Park, No-Wook;Lee, Yangwon
    • Korean Journal of Remote Sensing
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    • v.36 no.4
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    • pp.587-607
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    • 2020
  • Soil moisture is essential information for meteorological and hydrological analyses. To date, many efforts have been made to achieve the two goals for soil moisture data, i.e., the improvement of accuracy and resolution, which is very challenging. We presented an ensemble downscaling method for quality improvement of gridded soil moisture data in terms of the accuracy and the spatial resolution by the integration of BMA (Bayesian model averaging) and ATPRK (area-to-point regression kriging). In the experiments, the BMA ensemble showed a 22% better accuracy than the data sets from ESA CCI (European Space Agency-Climate Change Initiative), ERA5 (ECMWF Reanalysis 5), and GLDAS (Global Land Data Assimilation System) in terms of RMSE (root mean square error). Also, the ATPRK downscaling could enhance the spatial resolution from 0.25° to 0.05° while preserving the improved accuracy and the spatial pattern of the BMA ensemble, without under- or over-estimation. The quality-improved data sets can contribute to a variety of local and regional applications related to soil moisture, such as agriculture, forest, hydrology, and meteorology. Because the ensemble downscaling method can be applied to the other land surface variables such as temperature, humidity, precipitation, and evapotranspiration, it can be a viable option to complement the accuracy and the spatial resolution of satellite images and numerical models.

Factors Influencing Treatment Result and Early Complication in Inpatients with Psychiatric Comorbidity (정신질환 동반 입원 환자의 치료결과와 조기합병증에 영향을 미치는 요인)

  • Kim, Sang-Mi;Lee, Hyun-Sook
    • Korea Journal of Hospital Management
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    • v.22 no.4
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    • pp.113-122
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    • 2017
  • The purpose of the study was to investigate the patient, disease and hospital characteristics which affect treatment result and early complication for inpatients with psychiatric comorbidity. We analyzed data on 19,806 patients of the Korea Centers for Disease Control and Prevention from 2012 to 2014, Korea National Hospital discharge in-depth data. Frequency, chi-square and logistic regression analysis was performed, using STATA 12.0. According to logistic regression analysis, gender(Odds ratio(OR)=0.776, 95% confidence interval(CI)=0.686-0.878), insurance type(OR=0.853, CI=0.731-0.995), operation(OR=0.424, CI=0.350-0.513), disposition(OR= 39.307, CI=34.394-44.923), beds(300-499, OR=0.470, CI=0.377-0.585; 500-999, OR=0.462, CI=0.395-0.541; 1000 over, OR=0.598, CI=0.480-0.745) were significant predictors of treatment result. And insurance type(OR=1.527, CI=1.241-1.879), CCI(3 over, OR=1.865, CI=1.534-2.266), operation(OR=5.399, CI=4.562-6.389), disposition(OR=1.279, CI=1.013-1.614), district(Metropolitan city, OR=0.519, CI=0.407-0.661; Non-metropolitan OR=0.469, CI=0.383-0.574), beds(500-999, OR=2.799, CI=1.986-3.944; 1000 over, OR=2.109, CI=1.429-3.113) were significant predictors of early complication. This research would be used as a basic data of high quality of medical care and efficient resource utilization in order to detect and minimize the negative medical treatment results of inpatients with psychiatric comorbidity.

Analysis of Influencing Factors on the Outpatient Prescription of Antipsychotic Drugs in the Elderly Patients (노인환자의 항정신병 약물 원외처방 내역에 미친 영향 요인 분석)

  • Dong, Jae Yong;Lee, Hyun Ji;Lee, Tae Hoon;Kim, Yujeong
    • Korean Journal of Clinical Pharmacy
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    • v.31 no.4
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    • pp.268-277
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    • 2021
  • Background: Most antipsychotic drugs studies have been mainly conducted on side effects, randomized clinical trials, utilization rates, and trends. But there have been few studies on the influencing factors in elderly patients. The purpose of this study was to analyze the influencing factors on the outpatient prescription of antipsychotic drugs in the elderly patients. Methods: Active ingredients of antipsychotic drugs in Korea were selected according to the Korean Pharmaceutical Information Center (KPIC)'s classification. Data source was Korean Health Insurance Review and Assessment Service (HIRA) claims data in 2020 and target patient group was the elderly patient group. We extracted patients who have been prescribed one or more antipsychotic drugs and visited only one medical institution. Data were analyzed using descriptive statistics, chi-square, t-test, negative binomial regression. Results: A number of outpatients were 245,197 and prescriptions were 1,379,092. Most characteristics of patients were 75-85 year's old, female, health insurance type, no disease (dementia, schizophrenia), atypical drugs, cci score (>2) and characteristics of medical institution were neurology in specialty, rural region, general hospitals. Results of regression showed that patient's characteristics and medical center characteristics had significant effect on the outpatient prescription of antipsychotic drugs in the elderly patients. Conclusion: This study suggests that national policy of antipsychotic drugs in the elderly patients, with the consideration of the patients' and medical institutions' characteristics, is needed.

Effects of Herbal-Acupuncture with Inzinsammultang on the Recovery of Liver Injury in Rats (인진삼물탕(茵蔯三物湯) 약침처리(藥針處理)가 백서(白鼠)의 간손상(肝損傷) 회부(回復)에 미치는 영향(影響))

  • Choi, Sung-Hoon;Park, Hee-Soo
    • Journal of Pharmacopuncture
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    • v.2 no.1 s.2
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    • pp.111-133
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    • 1999
  • These studies were carried out to investigate the effect of Herbal-acupuncture with Inzinsammultang extract on the recovery from liver injury of rats. The liver injury of rats induced with 0.3ml/ea carbon tetrachloride. The Herbal-acupunture with Inzinsam multang extract solution inserted into corresponding focus of Kansu(BL18) in rats. In this study, SD-Rats(Sprague-Dawley) were divided into 4 groups ; Normal group (None treated group), Control-group(The group not treated after $CCI_4$-intoxication), Treated group; Example I-group(Saline-injected groups after $CCl_4$-intoxication) and Example II-group(Inzinsammultang-injected groups after $CCl_4$-intoxication). Through histological observation, Example II-group sho-ws that liver injury is weaker than Control group.(p<0.05) Biochemical assays for each serum enzyme activities of AST, ALT and LDH, levels of albumin, ${\gamma}$-GT, TG, total cholesterol were performed. The results were summarized as follows 1. AST(Aspartate aminotransferase) activity in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication. Inzinsammultang-injected groups after $CCl_4$-intoxication showed significantly higher AST activities, compared with the Saline-injected groups after $CCl_4$-intoxication.(p<0.05) 2. ALT(Alanine aminotransferase) activity in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication. The Inzinsammultang-injected groups after $CCl_4$-intoxication showed significantly higher AST activities, compared with the Saline-injected groups after $CCl_4$-intoxication(p<0.05) 3. Level of Albumin in serum significantly increased in the Inzinsarnmultang-injected groups after $CCl_4$-intoxication. 4. LDH(Lactate dehydrogenase) activities in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication.(p<0.05) 5. ${\gamma}$-GT(Glutamyl transferase) in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication(p<0.05) 6. As for the TG(Triglyceride) levels in serum, Inzinsammultang-injected groups after $CCl_4$-intoxication is no significant differences compared with the Saline-injected groups after $CCl_4$-intoxication.(p<0.05) 7. Total cholesterol in serum significantly increased in the Inzinsarnmultang-injected groups after $CCl_4$-intoxication.(p<0.05) Those results indicate that the Inzinsammultang Herbal-acupuncture have significant effects on the liver injury induced by $CCl_4$. So it is expected that the Inzinsammultang Herbal-acupuncture can be used to cure inflammations and recover the functions of damaged liver cells.

Effect of Cassia tora Ethanol Extracts on Carbon Tetrachloride-Induced Liver Injury in Rats (흰쥐에 있어서 사염화탄소 유발 간손상에 미치는 결명자 에탄올 추출물의 영향)

  • Ha, Tae-Youl;Cho, Il-Jin;Lee, Hyun-Yu
    • Korean Journal of Food Science and Technology
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    • v.33 no.6
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    • pp.789-794
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    • 2001
  • This study was conducted to investigate the effect of Cassia tora ethanol extracts on carbon tetrachloride($CCl_4$)-induced hepatotoxicity in rats. Male Sprague-Dawley rats were divided into the following 4 groups: normal group, $CCl_4$, treated group, $CCl_4-0.25%$ Cassia tora ethanol extracts group and $CCl_4-0.5%$ Cassia tora ethanol extracts group. Rats were fed with each experimental diet and water for 5 weeks. Liver weights of rats treated only with $CCl_4$, were significantly increased compared to normal group, but not in rats fed diet containing Cassia tora ethanol extracts. Cholesterol and triglyceride contents in serum and liver were also not influenced by either $CCl_4$, treatment or the supplementation of Cassia tora ethanol extracts. $CCl_4$, treatment significantly increased ALP activities, however the supplementation of Cassia tora ethanol extracts significantly decreased the activities of serum ALT, AST, ${\gamma}-GTP$ in dose-dependent manner. Cassia tora ethanol extracts significantly reduced $CCl_4-induced$ elevation of liver TBARS contents. Activities of superoxide dismutase and catalase were decreased by $CCl_4$, treatment, however by the supplement of Cassia tora ethanol extracts slightly increased activities of SOD and catalase. The activity of glutathione peroxidase in groups fed diets containing Cassia tora ethanol extracts was significantly decreased compared to that of the control group. These results suggest that Cassia tora ethanol extracts may exert protective effect against $CCl_4-induced$ liver injury through the prevention of lipid peroxidation.

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An Adaptive Resource Allocation Scheme in Cognitive Radio Network Assisted Satellite (무선 인지 네트워크에서 위성을 이용한 적응적인 자원 할당 기법)

  • Lee, Seon-Yeong;Sohn, Sung-Hwan;Jang, Sung-Jin;Kim, Jae-Moung
    • Journal of Satellite, Information and Communications
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    • v.4 no.2
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    • pp.5-11
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    • 2009
  • In this paper, we propose our design of adaptive resource allocation in the cognitive radio network assisted by satellite to improve the performance of Cognitive Radio user. Most of today’s telecommunication network operates in a fixed, licensed frequency band using a specific spectrum access network. However, the spectrum is not always used all the time, all the band. It causes the inefficiency in the spectrum usage. Thus, cognitive radio network is proposed to solve these spectrum inefficiency problems. The cognitive radio users (secondary users) are coexistent with primary users (PUs) who are licensed. That cognitive radio network is considered as lower priority comparing with primary user. So, the operation of the cognitive radio network is limited to interference constraints. Especially, when the number of secondary users increases, CCI among SUs will increase as well as interference to PU. That motivates our objective to improve the performance even if cognitive radio users increase. To solve this problem, we suggest an adaptive resource allocation scheme to improve the performance of cognitive radio network assisted by satellite. Through this algorithm, we can improve the cognitive radio network performance. And the simulation results confirm the effectiveness of our proposed algorithm.

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The Association between having a Usual Source of Care and Adherence to Medicines in Patients with Chronic Diseases (만성질환자의 상용치료원 이용과 복약순응도 간의 관계)

  • Jung, Youn;Byeon, Jinok
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.2
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    • pp.128-136
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    • 2016
  • Objective: This study was to explore the association between having a usual source of care and adherence to medicines in patient with chronic diseases. Methods: The 2012 Korea Health Panel was used as a data source. We analyzed 4,418 respondents that were diagnosed with chronic diseases and utilized health care services. Non-adherence to medication, a dependent variable, was defined as "not taking the medicines that were prescribed for treating chronic disease" or "not following the direction for medication". Whether having a usual source of care or not was used as a key independent variable, which was defined as having a regular site or a regular doctor for medical test, treatment, and consultation. Sex, age, education level, marital status, income, the type of health insurance, the number of chronic disease and CCI (Charlson Comorbidity Index) were included as covariates in the analysis. We conducted a multivariate logistic regression. Results: Totally, 30 percent of respondents reported to experience non-adherence to medication. Having a usual source of care was significantly associated with lower non-adherence to medication regardless its type, which is a regular doctor (OR=0.61, 95% CI=0.53-0.70) or a regular site (OR=0.67, 95% CI=0.58-0.78). Furthermore, having a usual source of care was associated with both of medication persistence (OR=0.66, 95% CI=0.54-0.81) and compliance (OR=0.65, 95% CI=0.56-0.76). Conclusion: Our results showed the possibility that usual source of care is able to conduct a positive role in improving adherence to medication with better management of chronic disease.