• Archives of Plastic Surgery
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• v.41 no.5
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• pp.466-471
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• 2014

Background Bleeding can be a problem in wound debridement. In search for an effective hemostatic agent, we experimented with a chitosan film combined with the recombinant human epidermal growth factor (rh-EGF), hypothesizing that it would achieve effective hemostasis and simultaneously enhance arterial healing. Methods Forty-eight Sprague-Dawley rats were used, and 96 puncture wounds were made. The wounds were divided into the following four groups: treated with sterile gauze, treated with gelatin sponge, treated with chitosan, and treated with chitosan combined with rh-EGF. Immediate hemostasis was evaluated, and arterial healing was observed histologically. Results Groups B, C, and D showed a significant rate of immediate hemostasis as compared to group A (P<0.05), but there were no significant differences among groups B, C, and D. Histologically, only group D showed good continuity of the vessel wall after 1 week. It was the only group to show smooth muscle cell nuclei of the vessel wall. Conclusions We observed that chitosan has an effective hemostatic potential and the mix of rh-EGF and chitosan does not interfere with chitosan's hemostatic capabilities. We also identified enhanced healing of vessel walls when rh-EGF was added to chitosan. Further research based on these positive findings is needed to evaluate the potential use of this combination on difficult wounds like chronic diabetic ulcerations.

• The Korean Journal of Ecology
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• v.26 no.4
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• pp.173-180
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• 2003

To clarify whether the closely related species living in the same area is a population or populations ecologically, leaf morphology, specific leaf area, and fruit and seed production were studied in the natural group of sect. Pes-gallinaceua of Corydalis of Namhansansung area from 1999 to 2000. There were 352 plants in one square meter and total eight species or varieties were identified. Of the 352 plants, the number of C. turtschaninovii was the most with 103(29.3%), and that of C. ambigua was the next with 78(22.2%), and that of C. turtschaninovii var. fumariaefolia was the smallest with 9(2.6%). In the 28 plants having spotted leaves, central leaflet did not parted or again parted. The extent of partition with the plant was various from non-parted type to perfectly two-parted type (three leaflet). Between two extreme types, there were diverse types so that this character formed a gradient. The rate of length/breadth was in the range of 0.79~2.17. This character was related to the extent of leaflet partition but did not well expressed the distinguishing trait along a species. The number and the type of serration were diverse and there was no sharp borderline among the species or varieties. Ecological properties, specific leaf area, the number of fruit per plant, and the number of seed per fruit, varied with a wide range in a species or variety but differences between species or variety were not significant. Therefore, the Corydalis group studied was regarded as a population on the three criteria: (1) possibility of interbreeding, (2) continuity of leaf morphology, (3) irrelevance between character and species, (4) similarity of several ecological properties.

• Journal of Korean Society of Steel Construction
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• v.27 no.6
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• pp.513-523
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• 2015

In steel moment frames constructed of H-shapes, strong-axis moment connections should be used for maximum structural efficiency if possible. And most of cyclic seismic testing, domestic and international, has been conducted for strong-axis moment connections and cyclic test data for weak-axis connections is quite limited. However, when perpendicular moment frames meet, weak-axis moment connections are also needed at the intersecting locations. Especially, both strong- and weak-axis moment connections have been frequently used in domestic practice. In this study, cyclic seismic performance of RBS (reduced beam section) weak-axis welded moment connections was experimentally investigated. Test specimens, designed according to the procedure proposed by Gilton and Uang (2002), performed well and developed an excellent plastic rotation capacity of 0.03 rad or higher, although a simplified sizing procedure for attaching the beam web to the shear plate in the form of C-shaped fillet weld was used. The test results of this study showed that the sharp corner of C-shaped fillet weld tends to be the origin of crack propagation due to stress concentration there and needs to be trimmed for the better weld shape. Different from strong-axis moment connections, due to the presence of weld access hole, a kind of CJP butt joint is formed between the beam flange and the horizontal continuity plate in weak-axis moment connections. When weld access hole is large, this butt joint can experience cyclic local buckling and subsequent low cycle fatigue fracture as observed in this testing program. Thus the size of web access hole at the butt joint should be minimized if possible. The recommended seismic detailing such as stickout, trimming, and thicker continuity plate for construction tolerance should be followed for design and fabrication of weak-axis welded moment connections.

• Interaction and multiscale mechanics
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• v.2 no.2
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• pp.129-151
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• 2009

This paper presents a meshfree procedure using a convex generalized meshfree (GMF) approximation for the large deformation analysis of particle-reinforced rubber compounds on microscopic level. The convex GMF approximation possesses the weak-Kronecker-delta property that guarantees the continuity of displacement across the material interface in the rubber compounds. The convex approximation also ensures the positive mass in the discrete system and is less sensitive to the meshfree nodal support size and integration order effects. In this study, the convex approximation is generated in the GMF method by choosing the positive and monotonic increasing basis function. In order to impose the periodic boundary condition in the unit cell method for the microscopic analysis, a singular kernel is introduced on the periodic boundary nodes in the construction of GMF approximation. The periodic boundary condition is solved by the transformation method in both explicit and implicit analyses. To simulate the interface de-bonding phenomena in the rubber compound, the cohesive interface element method is employed in corporation with meshfree method in this study. Several numerical examples are presented to demonstrate the effectiveness of the proposed numerical procedure in the large deformation analysis.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.24 no.3
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• pp.105-110
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• 1998

In the make-up product, Eye-shadow products have several purposes of enhancing product quality such as providing the beauty (variation of shape, clean appearance), feeling, continuity and adhesion. In this paper, newly developed wet type back injection press process is introduced so as to increase higher value products which providing various the beauty. The solvent takes an essential role to provide the fluidity of the powder bulk during the pressed-process of wet type pressed product. In this study, the effect of solvent in the oil binder was investigated, And the higher quality condition of the wet type pressed product was built to apply cosmetic preparation. Firstly, the system was designed powder phase as non treated pigment. The oil binder phase is categorized as hydrocarbons(Mineral oil, Squalane), Silicones(Methicone, Dimethicone ), esters (Octyldodecanol, Octyl Dodecyl Myristate). The solvent phase used was C 7-8 isoparaffin and Isopropyl Alcohol. The interaction of oil binder and solvent is investigated by measuring mass of final oil binder and the each solubility parameter. It was found that the higher the solubility the higher the degree of change in the final composition of the oil binder. In order to maintain the quality of the final product, the solvent used in pressed-process should be hydrophobic with oil binder.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.39-39
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• 2017

In Asia, sweet potato (Ipomoea batatas) is a very important crop for starch production. Approximately 74.3% of the total sweet potato production quantity is produced in Asia (FAO, 2014) and China is the largest producer of sweet potato. Post-harvest management is particularly important because it is difficult to maintain the quality as well as quantity of sweet potatoes. Despite the importance of post-harvest management, researches on sweet potato have been focused on production-related study such as breeding of new variety, improved techniques of cultivation, so there is limited research on storage after harvest. Curing is a normal practice after sweet potato harvest to promote wound healing and extend postharvest storage life. In Korea, harvested sweet potatoes are usually cured for 4 to 7 days at $30-33^{\circ}C$ and 80-95% relative humidity within one week. Since the optimum storage temperature of sweet potato is regarded as $15-20^{\circ}C$, additional facilities and costs are required to raise the temperature for curing. However, the majority of small farmers do not have the capacity to provide additional facilities and costs. This study was initiated to suggest a new curing method to accelerate the wound healing by applying chemical oxidation to the wound surface of sweet potato. Oxidative stress is known to play an important role in the synthesis of secondary metabolites including lignin. In addition, chemical oxidation can be applied to prevent spoilage caused by microorganisms. Powerful gaseous oxidant with excellent penetration ability and superior sterilization effect was selected for this study. Lignification, weight loss, and spoilage rate of artificially wounded sweet potatoes were investigated after oxidant fumigation. There were clear differences in morphological analysis such as lignification pattern, lignin deposition color, and continuity of lignified cell layers between oxidant-fumigated sweet potatoes and control. These results show that gaseous oxidant can be used to supplement or replace the curing practice, to improve shelf-life as well as curing cost reduction.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.3
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• pp.706-712
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• 2014

This paper describes a determining method of weighting factors for two-point interpolation filters. The interpolation filters is implemented by applying modifying functions to the linear interpolation. Here, there is a problem of determining weights when modifying functions being engaged. The previous method determined the weights by imposing c1-continuity on the interpolation kernels. However, this approach is unable to use the property of individual modifying functions. In this paper, on the basis of spectral analyses of the modifying functions and image signals, we provide a determination method by experimental results. Thus, many experiments are carried out to do so. The results indicate that different weights are required for different modifying functions and also the proposed method outperforms than the previous method.

• Journal of the Korean Vacuum Society
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• v.20 no.6
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• pp.422-429
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• 2011

Dependence of radical and ion density on electron density and temperature is numerically investigated for $Cl_2$/Ar, $CF_4$, $CF_4/O_2$, $CF_4/H_2$, $C_2F_6$, $C_4F_8$ and $SF_6$ discharges which are widely used for etching process. We derived a governing equation set for radical and ion densities as functions of the electron density and temperature, which are easier to measure relatively, from continuity equations by assuming steady state condition. Used rate coefficients of reactions in numerical calculations are directly produced from collisional cross sections or collected from various papers. If the rate coefficients have different values for a same reaction, calculation results were compared with experimental results. Then, we selected rate coefficients which show better agreement with the experimental results.

• Journal of the korean academy of Pediatric Dentistry
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• v.32 no.3
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• pp.576-583
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• 2005

Tooth formation is a complex developmental process that is mediated through a series of reciprocal epithelial-mesenchymal interactions. Several signal pathways and transcription factors have been implicated in regulating molar crown development, but relatively little is known about the regulation of root development. It was reported that NFI-C knockout mice showed abnormal root formation with normal crown. The aims of this study are to elucidate how the NFI-C regulate the determine of root shape and odontoblasts differentiation. We carried out immunohistochemistry using cytokeratin to investigate the role of Hertwig's epithelial root sheath and DSPP mRNA in-situ hybridization to conform the nature of root dentin during root development in NFI-C knockout mice. Cytokeratin reacted with all the HERS cells and the continuity of cytokeratin positive cells between the HERS cells and enamel epithelium was lost in the cervical region both wild and K/O types. After root dentin deposition cytokeratin positive-HERS cells showed irregularity and loss of polarity in the cervical region in K/O type. DSPP mRNA was strongly expressed in odontoblasts of crown and root dentin in wild type mice, whereas expression of DSPP mRNA was restricted in odontoblast of crown dentin in the K/O type. During root formation in NFI-C knockout mice, HERS normally grow out of the crown but fail to induce odontoblast differentiation in root portion. These results suggest that NFI-C may play important roles in odontoblast differentiation during root dentin formation.

• Journal of the Korean Dietetic Association
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• v.17 no.4
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• pp.416-428
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• 2011

This study was carried out to investigate the effects of breakfast service on nutritional status, hematological status, and attentiveness of children in low-income families. The subjects were 19 boys and 13 girls between 7 and 11 years old. The subjects were divided into a control group and a breakfast service (BS) group, in which 12 boys and 5 girls received breakfast from February 1 to December 31, 2010. The results can be summarized as follows: intakes of energy, protein, carbohydrate, calcium, iron, zinc, vitamin A, vitamin $B_2$, niacin, and vitamin C in the BS group were significantly higher than those in the control group. In the BS group, the intakes of calcium, folic acid, and vitamin C were lower than 75% of recommended intake levels. There were no significant differences in the total blood protein level and total cholesterol level between the BS group and control group. A blood albumin level was significantly higher in the BS group than in the control group. Systolic blood pressure was higher in the BS group than in the control group, whereas the diastolic blood pressure showed no significant difference between the groups. A dietary attitude score increased according to breakfast service and nutritional education. No significant differences were found in the capacity value and continuity value between the two groups, but the control value was significantly higher in the BS group than in the control group. Therefore, to sustain the effect of breakfast service and improve nutritional status for children skipping breakfast in low-income families, nutrition intervention services, as well as legal and financial support by the government should be provided.