• Journal of Contemporary Eastern Asia
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• v.15 no.1
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• pp.78-97
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• 2016

Living labs are an increasingly popular methodology to enhance innovation. Living labs aim to span boundaries between different organizations, among others Triple helix actors, by acting as a network organization typically in a real-life environment to foster co-creation by user-groups. This paper presents critical factors of Living labs in boundary-spanning between Triple Helix actors. Derived from a mixed-method approach and applications in the healthcare sector, the three main critical factors turn out to be 1) an adequate user-group selection and involvement, specifically a rich interaction and absorption of its results, 2) a balanced involvement of all relevant actors, and 3) a sufficient (early) attention for values, both values of user-groups and values of the management. People-oriented Living labs tend to differ from institution-oriented Living labs regarding these critical factors. Further, universities tend to take on diverse roles and strength of involvement, while the business sector tends to be actively involved only if this has been set as an explicit aim at start. The paper closes with a summary and future research paths.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.23 no.6
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• pp.569-575
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• 2014

In this study, the effect of cutting edge geometry, such as helix and rake angles, on surface roughness in ball-end milling is investigated by using the Taguchi method. A set of experiments adopting the $L_{27}(3^{13})$ design with an orthogonal array are conducted with special WC ball-end mills having different helix and rake angles. Analysis of variance (ANOVA) is performed to analyze the effects of tool geometry and machining parameters, such as cutting speed, feed per tooth, and depth of cut, on surface roughness. The ANOVA results reveal that helix and rake angles are critical factors affecting surface roughness; the interaction of helix angle and cutting speed is also important. This research can contribute to novel cutting edge designs of ball-end mills and optimization of cutting parameters.

• Honam Mathematical Journal
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• v.34 no.3
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• pp.381-390
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• 2012

In this paper, we give some characterizations for a quaternionic general helix by means of curvatures of a curve in a 4-dimensional Euclidean space.

• Communications of the Korean Mathematical Society
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• v.35 no.4
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• pp.1269-1281
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• 2020

In this article, we show that a pseudo-Hermitian magnetic curve in a normal almost contact metric 3-manifold equipped with the canonical affine connection ${\hat{\nabla}}^t$ is a slant helix with pseudo-Hermitian curvature ${\hat{\kappa}}={\mid}q{\mid}\;sin\;{\theta}$ and pseudo-Hermitian torsion ${\hat{\tau}}=q\;cos\;{\theta}$. Moreover, we prove that every pseudo-Hermitian magnetic curve in normal almost contact metric 3-manifolds except quasi-Sasakian 3-manifolds is a slant helix as a Riemannian geometric sense. On the other hand we will show that a pseudo-Hermitian magnetic curve γ in a quasi-Sasakian 3-manifold M is a slant curve with curvature κ = |(t - α) cos θ + q| sin θ and torsion τ = α + {(t - α) cos θ + q} cos θ. These curves are not helices, in general. Note that if the ambient space M is an α-Sasakian 3-manifold, then γ is a slant helix.

• The Korean Journal of Health Service Management
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• v.13 no.3
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• pp.81-92
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• 2019

Objectives: This study aimed to investigate the effects of auricular acupressure on anxiety and sleep among patients undergoing chemotherapy for breast cancer. Methods: A nonequivalent control group nonsynchronized design was employed. The experimental group received auricular acupressure on specific acupoints (shenmen, heart, kidney, subcortex), and the control group received auricular acupressure on helix 1, helix 2, helix 3, and helix 4 three times a day for three weeks. A total of 60 women were divided into an experimental (n=30) and control (n=30) group. Patient recruitment occurred between May and August 2019. The collected data were analyzed by a chi-square test, paired t-test, and independent t-tests using the SPSS 21.0 program. Results: There was a significant decrease in anxiety(t=4.61, p=<.001) and increase in sleep(t=3.81, p=<.001) in the experimental group compared to the control group. Conclusions: The findings confirm that auricular acupressure is an effective nursing intervention to decrease anxiety felt by patients undergoing chemotherapy and to increase the quality of their sleep.

• Nonlinear Functional Analysis and Applications
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• v.26 no.2
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• pp.225-236
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• 2021

In this paper, we determine position vector of a line of curvature of a regular surface which is relatively normal-slant helix, with respect to Darboux frame. Then, a vector differential equation is established by means Darboux formulas, in the case of the geodesic torsion is vanishes. In terms of solution, we determine the parametric representation of a line of curvature which is relatively normal-slant helix, with respect to standard frame in Euclidean 3-space. Thereafter, we apply this result to find the position vector of a line of curvature which is isophote curve.

• FLOWER RESEARCH JOURNAL
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• v.16 no.1
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• pp.28-35
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• 2008

Eleven accessions of Hedera helix, three accessions of Hedera rhombea, one accession of Fatshedera lizei, and one accession of Fatsia japonica were collected and their genetic diversity was measured by using 10 RAPD primers. Approximately ninety seven percentage of polymorphism was detected, because broad germplasm, three genus, was used. Total 97 bands were scored and a dendrogram was constructed by using an UPGMA method. Accessions belonging to Hedera helix tightly clustered in one group: eight accessions showed extremely narrow genetic differences and the other three accessions also showed significant similarity. Despite of their genetic similarity, they showed morphological variations. The morphological variation with a narrow genetic differences indicated that the ivy cultivars have been indeed developed from a mutation breeding program. Genetically most unrelated Fatsia japonica showed a genetic distance of 0.63 on the average between other species. An accession from Fatshedera lizei developed by crossing between two genus, Hedera helix and Fatsia japonica, was allocated together with accessions from Hedera rhombea.

• Honam Mathematical Journal
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• v.36 no.1
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• pp.113-129
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• 2014

In this study, we have investigated the possibility of whether any Frenet plane of a given space curve in a 3-dimensional Euclidean space $\mathbb{E}_3$ also is any Frenet plane of another space curve in the same space. We have obtained some characterizations of a given space curve by considering nine possible case.

• Biomolecules & Therapeutics
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• v.22 no.1
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• pp.41-46
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• 2014

Enterovirus 71 (EV71) is the predominant cause of hand, foot and mouth disease (HFMD). The antiviral activity of hederasaponin B from Hedera helix against EV71 subgenotypes C3 and C4a was evaluated in vero cells. In the current study, the antiviral activity of hederasaponin B against EV71 C3 and C4a was determined by cytopathic effect (CPE) reduction method and western blot assay. Our results demonstrated that hederasaponin B and 30% ethanol extract of Hedera helix containing hederasaponin B showed significant antiviral activity against EV71 subgenotypes C3 and C4a by reducing the formation of a visible CPE. Hederasaponin B also inhibited the viral VP2 protein expression, suggesting the inhibition of viral capsid protein synthesis.These results suggest that hederasaponin B and Hedera helix extract containing hederasaponin B can be novel drug candidates with broad-spectrum antiviral activity against various subgenotypes of EV71.

• Journal of the Korean Magnetic Resonance Society
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• v.19 no.3
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• pp.149-155
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• 2015

Acyl carrier protein is related with fatty acid biosynthesis in which specific enzymes are involved. Especially, acyl carrier protein (ACP) is the key component in the growing of fatty acid chain. ACP is the small, very acidic protein that covalently binds various intermediates of fatty acyl chain. Acylation of ACP is mediated by holo-acyl carrier protein synthase (ACPS), which transfers the 4'PP-moiety of CoA to the 36th residue Ser of apo ACP. Acyl carrier protein P (ACPP) is one of ACPs from Helicobacter plyori. The NMR structure of ACPP consists of four helices, which were reported previously. Here we show how acylation of ACPP can affect the overall structure of ACPP and figured out the contact surface of ACPP to acyl chain attached during expression of ACPP in E. coli. Based on the chemical shift perturbation data, the acylation of ACCP seems to affect the conformation of the long loop connecting helix I and helix II as well as the second short loop connecting helix II and helix III. The significant chemical shift change of Ile 54 upon acylation supports the contact of acyl chain and the second loop.