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Effects of natural eggshell membrane (NEM) on monosodium iodoacetate-induced arthritis in rats (MIA 유도 골관절염 랫드에 Natural Eggshell Membrane (NEM)이 미치는 영향)

  • Sim, Boo Yong;Bak, Ji Won;Lee, Hae Jin;Jun, Ji Ae;Choi, Hak Joo;Kwon, Chang Ju;Kim, Hwa Young;Ruff, Kevin J.;Brandt, Karsten;Kim, Dong Hee
    • Journal of Nutrition and Health
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    • v.48 no.4
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    • pp.310-318
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    • 2015
  • Purpose: The aim of this study is to investigate anti-arthritis activity using natural eggshell membrane (NEM). Methods: NEM was administered at 52 mg/kg, 200 mg/kg, and 400 mg/kg to SD-Rat, where arthritis was induced by monosodium iodoacetate (MIA) at 3 mg. NO production in serum was measured using Griess reagent. Cytokines including IL-$1{\beta}$, and IL-6 were measured by Luminex and $PGE_2$, MMP-2, MMP-9, TIMP-1, $LTB_4$, and hs-CRP were measured by ELISA. The cartilage of patella volume was examined and 3-D high-resolution reconstructions of the cartilage of patella were obtained using a Micro-CT system. Results: Production of NO, IL-$1{\beta}$, IL-6, $PGE_2$, MMP-2, MMP-9, TIMP-1, $LTB_4$, and hs-CRP in serum was decreased, respectively, in comparison with control. The cartilage of patella volume increased significantly. In addition, the NEM group showed a decrease in the cartilage of patella, synovial membrane, and transformation of fibrous tissue. Conclusion: The results for NEM showed significant anti-arthritis activity. These results may be developed as a raw material for new health food to ease the symptoms mentioned above.

A Study of the Real Conditions of the Management of Dental Hygienists' Self-Oral Health (치과위생사의 자기구강건강관리에 관한 연구)

  • Lee, Kyung-Ae
    • Journal of dental hygiene science
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    • v.5 no.2
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    • pp.45-49
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    • 2005
  • This study is designed to present basic materials necessary for offering the more effective way of dental hygienists, or those who are in charge of the education of Oral health, the treatment and prevention of dental problems, educating Oral health by stage by dint of determining the actual condition of the knowledge and management of dental hygiene, or prevention of the basic dental disease except the professional methods of dental management and evaluating their abilities to manage dental hygienes. In terms of the real conditions of the management of dental hygienes, the majority of the subjects said, "not bad" or "healthy". Most of them (62.1%) said that they brush their teeth three times a day, and most of them (85.2%) depend on rolling methods. 69.2% of them used brushes that are neither hard nor soft, and 28.4% of them use soft brushes and 49.7% of them brush their teeth for about 3 minutes. In terms of brushing time, 27.8% of them brush their teeth after lunch, while 23.8% of them brush their teeth after breakfast. 66.3% of them use fluoric tooth pastes while 19.5 percent of them said, "I have no idea." and 14.2% of them said, "No." In terms of complementary dental hygiene goods, dental goggles are used by 23% of them, and dental threads are used by 78.1% and tooth brushes are used by 78.1% of them, and 42.4% of the subjects use the instruments one to twice a day, and 53.8% of them use them for less than one minute a time. In terms of dental health care, 17.2% of them have a chew of gum and 8.3% of them pay a regular visit to dental clinics and 5.3% of them don't smoke.

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Moisturizing Effect and Durability of Sun Protection Factor (UVA/B) Activity with Multiple Emulsion (W/O/W) System (멀티플 에멀전(W/O/W) 시스템을 이용한 자외선차단성능(UVA/B)의 내수성과 보습효과)

  • Lee, Myoung-Hee;Kim, In-Young
    • Journal of the Korean Applied Science and Technology
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    • v.32 no.2
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    • pp.339-347
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    • 2015
  • This study is to evaluate moisturizing effect and durability of UV A/B blocking activity with multiple (W/O/W) emulsion system. Most of the sun protective products come to be hot issue having both high SPF and long-lasting activity as using special products when is going out, mountain climbing and sports. Also, many consumers prefer the products which have the excellent waterproofing activity of sun care cosmetics as well as the non-sticky feeling that carried out the study of the sensorial science and texture preference. Therefore, development of the specific formulation using this multiple (W/O/W) emulsion technology, it has O/W type hydro skin feel having soft and moist texture when it is treated on the skin. Finally, this formulation is instantly changed to W/O type feel after adsorbed into the skin. The purpose of this study is to get high SPF lasting effect having high water resistance tactivity with high functional multiple (W/O/W) emulsion cream. We used major ingredients, UV-B absorbers were selected with ethylhexyl methoxycinnamate, isoamyl-p-methoxycinnamate, ethylhexylsalicylate, and octocrylene, UV-A absorbers were selected with butylmethoxydibenzoylmethane, bis-ethylhexyloxyphenol methoxy phenyltriazine. SPF effect of O/W type cream was 34.1. SPF effect of W/O/W type cream was 40.6 (increased about 19%). Water resistance effect after 4 hours, SPF effect of O/W type cream was 3.6 (quickly drop down). SPF effect of W/O/W type cream having 81.0 % waterproofing effect was 32.7 (decreased about SPF 7.9). Moisturizing effect of O/W cream at first was superior comparing multiple emulsion. But after 3 hours quickly was drop-down. Moisturizing effect of multiple emulsion was high comparing O/W type and other sun block creams after 4 hours was constantly maintaining water-content.

The status of 「Logic and Writing in Home Economics Education」 course and the students' perception about the course (「가정과 논리 및 논술」 교과목의 운영 실태 및 가정교육과 학생의 인식)

  • Choi, Min-Ji;Chae, Jung-Hyun;Jun, Mi-Kyung
    • Journal of Korean Home Economics Education Association
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    • v.27 no.1
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    • pp.51-65
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    • 2015
  • The purpose of the study was to describe the operating status of "Logic and Writing in Home Economics Education(HEE)" course and the students' perception about the course. For this study, the syllabuses of "Logic and Writing" course in HE education department were reviewed. The survey method was used in this descriptive study. Respondents in this study were 116 students taking the "Logic and Writing in Home Economics Education" course. Questionnaires from the students were collected through on-line and off-line mail. The results of the study were as the follows: First, goals of the "Logic and Writing in HE Education" course were as the follows in order: to enhance writing skill about various subjects related to Home Economics; to foster HE teachers' professionalism through persuasive power logically; to foster writing skill logically; to prepare HE teacher recruitment exam; and to foster teaching skills to enhance students' writing. The student evaluation methods in the course were mainly attendance, examination, tasks, discussion and presentation, and class participation. Second, degree of satisfaction of students taking the course was higher than average. The student respondents perceived that the course was helpful to improve their logical thinking and critical analytical skill, writing skill related to HE education and education, ability to express one's opinion clearly and exactly, understanding of the fundamental concept of logic and the structure and method of the essay, comprehensive understanding of HE education, and ability to solve the problems specifically. However, they responded that it was difficult to practice writing, to discuss and debate frequently, to follow uncertain assessment criteria, and to present frequently. They wanted the instructor to give the feedback more frequently.

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The Study of Effect and Safety related to Dong-gi Acupuncture(DGA) and Complex therapy on Lumbago due to blood stasis and sprain (좌섬(挫閃)·어혈(瘀血) 요통(腰痛)에 동기침법(動氣鍼法) 및 복합치료(複合治療)의 유효성(有效性) 및 안정성(安定性) 연구(硏究))

  • Kim, Kee-Hyun;Lim, Hyung-Ho;Hwang, Hyeon-Seo;Song, Ho-Sueb;Song, Young-Sang;Kwon, Soon-Jung;Kim, Kyung-Nam;Ahn, Koang-Hyun;Lee, Seong-No;Kang, Mi-Suk;Gyun, Im-Jung
    • Journal of Acupuncture Research
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    • v.19 no.3
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    • pp.107-114
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    • 2002
  • Objective : This study was designed to find the most effective and safest way to overcome Lumbago due to blood stasis and sprain involved in a few Meridian Tendino-musculatures by evaluating the effect of two kinds of Dong-gi(Dong-qi) Acupuncture(DGA) and by reporting their side effects. Material : 97 patients of out and admission patients were selected, who were diagnosed with lumbar sprain caused by repetitive bending, heavy weight lifting, unsuitable posture, concussion and falling down and whose Lumbago due to blood stasis and sprain in the concept of oriental medicine. Methods : 97 patients were divided into three groups. One is exclusive DGA group to which DGA and the method retaining needles on the acupoints for about 20 minutes were applied, the other is DGA combined active exercise group in which patients stretched their Meridian Tendino-muscuIatures with their hips moving up and downward repeatedly during DGA, the third is DGA combined passive exercise group in which patients were made to flex or extend their bodies on the auto flexion-distraction table in a prone position, from 10 to 20 degree, during DGA. In each group, bed rest, physical therapy and herbal medicine were used according to symptoms, in addition to DGA. In DGA method, "Su(Shu)" points of the meridian related to the involved Meridian Tendino-musculature were mainly chosen, that is, Sokkol(Shugu, B65), Hugye(Houxi, SI3), ChungJo(Zhongzhu, TE3) were used, for most LBP belonged to Bladder and Gallbladder Meridian Tendino-musculature disorders. Pyong-Bo-Pyong-Sa(Ping-Bu-Ping-Xie) such as Dong-Gi and Yeom-Jeon(Nian-Zhuan) was applied as Bo-Sa method. For evaluation of effectiveness, new score system was devised by severity of pain and range of movement. the score was given twice at patients' first and last visit and the difference between first and last score was regarded as a evaluation scale, the effectiveness was classified into four grade by evaluation scale.(scale : 12-15; excellent, 8-11; good, 4-7; fair, 0-3; bad) Results : 1. Exclusive DGA, DGA combined active exercise and DGA combined passive exercise group showed 97, 87 and 89% in effectiveness. 2. Exclusive DGA, DGA combined active exercise and DGA combined passive exercise group showed no aggravation of pain, range of movement. 3. In blood test of 34 patients, only one patient showed abnormal rise of sGOT, sGPT and $\gamma$-GTP at his first visit and the others didn't show any detrimental change. DGA had no bad influence upon BUN and creatinine of patients. Conclusion : For complex theraphy combining DGA, exercise, physical therapy and Herbal medicine proved to be highly effective on treating lumbago due to blood stasis and sprain, this is expected to be available for clinical use.

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Synthesis of Artificial Zeolite from Fly Ash for Preparing Nursery Bed Soils and the Effects on the Growth of Chinese Cabbage (석탄회(石炭灰)를 이용한 육묘(育苗) 상토용(床土用) 인공(人工) 제올라이트의 제조와 배추 생육에 미치는 효과(效果))

  • Kim, Yong-Woong;Lee, Hyun-Hee;Yoon, Chung-Han;Shin, Bang-Sup;Kim, Kwang-Sik
    • Korean Journal of Soil Science and Fertilizer
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    • v.31 no.2
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    • pp.95-106
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    • 1998
  • To reduce the environmental contamination and to utilize fly ash massively produced from the coal power plant every year, we synthesized the artificial zeolite using fly ash treated with alkaline, and then analyzed the mineralogical and morphological properties by X-ray, IR, and SEM. The amount of $NH_4{^+}$, $K^+$, and $H_2PO_4{^-}$ adsorbed by the fly ash and the artificial zeolite were determined with reaction time, amount of adsorbate used, ion concentrations. The results obtained from the pot experiments packed with the top soil, amended with granulated artificial zeolite which was made by treatment of 4% polyvinylalcohol, showed that CEC of the artificial zeolite was $257.7cmol^+kg^{-1}$, that was almost 36 times greater than that of fly ash. The ratio of $SiO_2/Al_2O_3$ decreased but the amount of Na increased. The physico-chemical properties analyzed by X-ray, IT, and SEM represented that the artificial zeolite synthesized had a similar morphological structure to that of the natural zeolite. The structures of the artificial zeolite had a significantly enlarged surface having a lot of pores, while the fly ash looked like spherical smooth shape with having not pores on the surface. Thus, the artificial zeolite was successfully synthesized. The results of adsorption isotherms of fly ash and artificial zeolite showed that the amount of $NH_4{^+}$, $K^+$, and $H_2PO_4{^-}$ adsorbed increased as the equilibrium concentration increased, while $NH_4{^+}$ was strongly adsorbed on the surface of fly ash and artificial zeolite than that of $K^+$. The most distinctive growth of Chinese cabbage was found from the top soil(NPK + soils + 20% of granulated artificial zeolite + 5% of compost). Therefore, we concluded that one of the most effective methods to effectively recycle a fly ash was to make the artificial zeolite as we did in this experiment.

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Effect of Reduced N Application and Planting Density on Paddy Rice (수도에 대한 질소감량시비 및 재식밀도의 영향)

  • Hong, Ki-Chang;Shim, Jae-Han;Seo, Yong-Tack;Park, Ro-Dong;Kim, Kil-Yong;Shon, Boe-Kyun;Kim, Yong-Woong
    • Korean Journal of Soil Science and Fertilizer
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    • v.32 no.1
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    • pp.12-21
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    • 1999
  • This study was carried out to improve the cultivation method of paddy rice when the application amount of nitrogen decreased. We investigated the growth and the yield of paddy rice, the changes of nutrients in the soil solution, soil and paddy rice. The results are as follows. The yield at the N4 plot(N $73kg\;ha^{-1}$) was higher than that of control(N $110kg\;ha^{-1}$). N1(N $55kg\;ha^{-1}$), N2(N $55kg\;ha^{-1}$), and N3(N $73kg\;ha^{-1}$). The number of panicle per square meter at the N4 plot was larger than that of control plot. The increase in yield at the N4 plot was due to increased number of panicle where planting density was two times higher compared to the control plot. The availability of nitrogen at the N4 plot also was two times higher than that of control plot. The pH in soil solution was around 7 and did not change largely. The $K^+$ concentration in soil solution at all plots decreased gradually. The $Ca^{2+}$ concentration in soil solutions increased gradually, and decreased at the later stage slightly. The P concentration in soil solution decreased gradually, increased after the heading stage, and then decreased due to decrease of soil temperature. Leaching of $Ca^{2+}$ was higher, while that of $K^+$ and P was lower compared to other ions. Total content of nutrients in soil after harvest decreased. Contents of total N, total P, and O.M. at the N4 plot were higher than those of the other plots. The content of total N and O.M. was correlated to yield. Contents of N, P and K in rice straw and grain at the N4 plot were the highest among all plots. In conclusion, to decrease N application amount in paddy rice cultivation as well as to maintain yield, planting density should be twice of control and the amount of application of N fertilizer should be two-third of control where N fertilizer should be applied mainly at 20 and 10 day before heading.

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A Study of Sulfur Nutrition on the Flavour Components of Garlic (Allium sativum L.) (유황성분(硫黃成分)이 마늘의 향기성분(香氣成分)에 미치는 영향(影響))

  • Chang, Ki Woon;Hwang, Joon Young;Woo, In Shik
    • Korean Journal of Soil Science and Fertilizer
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    • v.21 no.2
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    • pp.183-193
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    • 1988
  • The relationship between the sulfur fertilization, and the quality and yield of garlic was investigated. The garlic was grown in pot and field at the five fertilization levels of sulfur. The growth characteristics, yield and flavour components of the garlic were studied. The results were summarized as follows; 1. The sulfur applications contributed to a weight and yield of the bulb in SP-10 (10kg/10a) and SF-20 (20kg/10a) significantly, respectively. 2. From the volatile oil obtained by steam distillation of garlic, fourteen organie sulfur components were separated, identified and quantified by GC and GC/MASS and the SP-10 and SF-20 were higher in the concentration of the flavour components in the volatile oil than other treatments. 3. It is considered that the organic sulfur components were synthesized in the top and transported to the bulb of the garlic. 4. In conclusion, SF-20, 20kg/sulfur per 10a, could be recommended to get maximum yield and a good quality of garlic in view of evaluation through the contents of organic sulfur components in the volatile oil and the yield of the bulb.

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Effect of Heat Insulation on Decomposition of Ricestraw Pile in the P.E.Film House during Winter Season (겨울철 비닐하우스내의 볏짚퇴비더미의 온도변화와 부숙효과)

  • Lee, Yun Hwan;Kim, Yong Yeon
    • Korean Journal of Soil Science and Fertilizer
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    • v.18 no.1
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    • pp.27-31
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    • 1985
  • To get well matured farm yard manure from ricestraw as quickly as possible during winter season, straw piles wrapped with polyethylene film and/or straw thatch were stored in the vinyl house or open air. Their maturities and changes of temperature in heap were investigated from the beginning of December 1983 to March of next year. Heat increment in vinyl house was high $2-5^{\circ}C$ than at open air at the lowest temperature but it didn't rise over the freezing point. However, the highest temperature was arisen over than $20^{\circ}C$ averagely at the vinylhouse compared to those of open air during three months. Temperature in piles of straw manure was reached to about $70^{\circ}C$ in maximum and rose again very rapidly after repiling in the vinyl house, whereas increment of temperature after repiling was delayed and took long times to reach the maximum temperature at open air. Wrapping with P.E. film also affected the insulation of decomposing heat of straw pile and promoted the repeat of piling even at open air. By these results, ricestraw would be decomposed rapidly by insulation with P.E. film in the vinyl house and could be reached to matured compost for application to field on next spring season. P.E. film covered for vinyl house was endured until May of next year without tear by weathering.

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A Study on Changes of Entrepreneurial Ecosystem on Women Entrepreneurial Intentions (창업생태계 변화가 여성창업의지에 미치는 영향)

  • Jeon, Hyejin;Park, JaeWhan
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.10 no.2
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    • pp.85-96
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    • 2015
  • Korea is one of low-ranked countries in women's economic participation rate among OECD nations because well-educated females are not participating in economic activities. Regardless of current state of our society, opening a business is being considered as a effective method for job creation. Also, increasing the number of female business founders can lead to female job creation which promotes even growth of foundation and job creation and augments women's economic activity rate. Therefore, this study suggests the direction of foundation and inspires foundation factors and aims at increasing social re-participation through vitalization of business foundation by women in career discontinuity. For this study, I carried out a survey targeting career interrupted women who have attained entrepreneurial education using five- point scale by Likert and analyzed with SPSS Windows 18.0. The analysis set up 3 hypotheses with independent variables of psychological traits, entrepreneurial education and entrepreneurial environment and the dependent variable of entrepreneurial intention of the career interrupted women. Also, I looked if there is the modify effect when psychological traits and entrepreneurial education affect the entrepreneurial intention with entrepreneurial environment as a moderating variable. To summarize the positive analysis result, Firstly, all psychological traits, entrepreneurial education and entrepreneurial environment had similar positive affects on career interrupted women's entrepreneurial intention. Secondly, when psychological traits and entrepreneurial education affect the entrepreneurial intention, entrepreneurial environment had similar effects as a moderating effect. This study implies that psychological traits, entrepreneurial education and entrepreneurial environment are all important for the career interrupted women's entrepreneurial intention. There are so many women who are going through both professional experience and personal network's severance. Therefore, optimized entrepre neurship education must be provided to help those women return to economic activity considering their psychological traits. Additionally, we should put emphasis on producing the entrepreneurial environment that can positively convert others' perceptions and construct those women's personal network. There seems to be more productive information for the strategies which can induce those women's actual business foundation if the social problems of the women who have highly willing to open a business are treated in the future. Also, considering that psychological traits, entrepreneurial education and entrepreneurial environment all have effect on entrepreneurial intentions, there should be more related follow-up study on this.

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