• Title/Summary/Keyword: ${\mu}-CT$

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The evaluation of useful on the additional PET/CT Liver scan (PET/CT 검사에서 Gastrointestinal Cancer 환자의 Liver 추가촬영에 대한 유용성 평가)

  • Park, Se Youn;Lee, Hwa Jin;Lee, Mu Seok;Kim, Jung Uk;Ji, Hye In
    • The Korean Journal of Nuclear Medicine Technology
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    • v.20 no.2
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    • pp.46-48
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    • 2016
  • Purpose The liver one of the most common site for distant metastasis for a variety of tumor, especially of gastrointestinal origin. the purpose of this study was to analyze image quality between standard scan and additional liver scan. Materials and Methods From September 2015 to February 2016. 152 patients were examined undergo gastrointestinal cancer. 32 patients confirmed liver metastasis analyzed same liver ROI level and check the SNR, SUV and T/N ratio Results The $SNR_{mean}$ of standard was $17.7{\pm}10.3$; addition was $22.3{\pm}9.7$ (p<0.05). In $SUV_{max}$ of standard was $6.7{\pm}2.8$; addition was $7.6{\pm}3.2$ (P<0.05). and the T/N ratio of standard was $2.1{\pm}0.6$; addition was $2.5{\pm}0.8$ (P<0.05). Conclusion The $SNR_{mean}$, $SUV_{max}$ and T/N ratio were higher than those on the first scan (P<0.05). The SNRmean showed the highest change rate among the parameters. A additional liver scan is more favorable for the detection of gastrointestinal cancer patients.

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Development of Bladder Phantom and Image Evaluation of Lesion in the Vicinity according to Filling and Empty Bladder (방광 팬텀 제작을 통한 충만여부에 따른 방광 주변 병변에 대한 영상 평가)

  • Park, Chan-Rok;Kim, Jae-Il;Lee, Hong-Jae;Kim, Jin-Eui
    • The Korean Journal of Nuclear Medicine Technology
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    • v.20 no.1
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    • pp.24-27
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    • 2016
  • Purpose In this study, we evaluated image quality of lesion in the vicinity according filling and empty bladder developing bladder phantom. Materials and Methods Bladder phantom was developed by modifying NEMA IEC body phantom. Air-balloon was described as bladder and 6 insert were set as lesion in the vicinity bladder according to distance. The images were evaluated in terms of % BV, comparison of SUV and peak count rate (Single, Random and True count). Results % BV was decreased far away from bladder. There were different for SUV about $7.8{\pm}3.8%$ between filling and empty bladder. True count rate was decreased about 38 %. Single and random count were increased about 44, 61%. Conclusion When the lesion is close to bladder, noise is increased. That's why prior to PET-CT scan, It is important to urinate. and It helps patient to get the accurate result.

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The Effect of Microcurrent Electrical Stimulation on Muscle Atrophy Suppression in a Sciatic Nerve Injured Rat Model; Comparative Study by Current Intensity (좌골신경손상 쥐 모델을 이용한 미세전류 자극의 근위축 억제 효과 확인 및 자극 세기 별 비교)

  • Hwang, Donghyun;Kim, Seohyun;Lee, Hana;Jang, Seungjun;Kim, Sebin;kim, Tackjoong;Choi, Sooim;Kwak, Hoyoung;Kim, Han Sung
    • Journal of Biomedical Engineering Research
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    • v.38 no.4
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    • pp.175-182
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    • 2017
  • Microcurrent electrical stimulation(MES) has been used to accelerate recovery of atrophied skeletal muscle. However, convincing stimulation parameters for suppressing muscle atrophy due to injured sciatic nerve remains unclear. The objective of this study was to investigate the effective intensity of MES on restraining muscle atrophy with rat model underwent sciatic nerve injury(SNI). Twenty-5-week-old Sprague Dawley male rats were equally assigned to five groups : Control group(Control, CON, n = 4), Denervation group(Denervation, D, n = 4), Denervation with MES of $22{\mu}A$ group(Denervation + $22{\mu}A$, D+22, n = 4), Denervation with MES of $100{\mu}A$ group (Denervation + $100{\mu}A$, D+100 n = 4), Denervation with MES of $400{\mu}A$ group(Denervation + $400{\mu}A$, D+400, n = 4). To induce muscle atrophy, all rats in the D, D+22, D+100, and D+400 groups, were subjected to sciatic nerve injury on their right hindlimb and allowed to have 1 week of resting period. Following this period, rats underwent daily MES(60 min/ a day, 5times/1week) for 4 weeks. After that, we investigate morphological changes in muscle volume by using in vivo micro-computed tomography at week 0, 1, 3 and 5. After 5 weeks, the muscle volume had the highest value in D+400 group, and also noticeably increased in D+100 group compared to it in D group. The results of this study imply that MES with current intensities between $100-400{\mu}A$ can suppress muscle atrophy effectively.

Effects of Sayeok-tang on Papain-Induced Osteoarthritis in Mice (Papain으로 유도된 골관절염 생쥐 모델에서 사역탕(四逆湯)의 항골관절염 효능에 관한 연구)

  • Kung, Shyang En;Oh, Min Seok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.27 no.2
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    • pp.212-224
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    • 2013
  • This study intends to clarify how Sayeok-tang(here in after reffered to SYT) affect C57BL/10 mice whose osteoarthritis was induced by papain. Osteoarthritis was induced by injecting papain in the knee joint of 3 groups(n=6) of mice. Normal group was non-treatment group and was not injected papain, whereas control mice were orally administered with $200{\mu}{\ell}$ of physiological saline. Positive comparison group was medicated with 100 mg/kg of Joins$^{(R)}$ mixed with $200{\mu}{\ell}$ of physiological saline. Experimental group was medicated with 400 mg/kg of SYT mixed with $200{\mu}{\ell}$ of physiological saline. Both Positive and experimental comparison groups were orally medicated once per day for 4 weeks. After the experiment, the functions of liver and kidney, inflammation cytokine values within serum, degree of revelation for inflammation cytokine genes, immune cells within blood, metabolism of arachidonic acid and amount of cartilage were measured and histopathological changes in the knee joint structures were observed. As results, SYT had no significant effect on the liver and kidney functions. Interleukin-$1{\beta}$(IL-$1{\beta}$), interleukin-6(IL-6), monocyte chemo attractant protein-1(MCP-1) and tumor necrosis factor-${\alpha}$(TNF-${\alpha}$) were significantly decreased. Inflammation cytokines in joints were all significantly decreased. Prostaglandin $E_2(PGE_2)$, thromboxane $B_2(TXB_2)$ were significantly decreased. Destruction of cartilage on micro computed tomography(CT)-arthrography was meaningfully decreased. In terms of histopathology, infiltration of inflammation, proliferation of synovial membrane, subsidence of cartilage and bone due to penetration of excessive formation of synovial cell and destruction of cartilage were small. Based on all results mentioned above, Sayeok-tang(SYT) is believed to be meaningful for suppressing the progress of osteoarthritis and its treatments because of its anti-inflammatory effects and alleviation of pain with histopathological effective efficacy.

탄소와 질소 함량 변화에 따른 type 347 스테인리스강의 피로균열거동 연구

  • Min, Gi-Deuk;Kim, Dae-Hwan;Lee, Bong-Sang;Kim, Seon-Jin
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2009.05a
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    • pp.42.1-42.1
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    • 2009
  • 오스테나이트 스테인리스강은 우수한 내식성 및 기계적 특성으로 인해 구조용 재료로 널리 사용되고 있다. 표준원전 경수로의 경우 가압기 밀림관소재로 Nb 안정화 오스테나이트 스테인리스강인 type 347 스테인리스강이 사용되고 있다. 그러나 원전배관에서는 운전중 배관내 온도편차에 의한 열응역과 하중변화에 의한 기계적하중에 의해 피로손상을 받는다. 일반적으로 범용 오스테나이트 스테인리스강(AISI 304, 316)의 피로균열 성장거동에 대한 연구결과는 국내외적으로 다수 축적되어 있으나 type 347 탄소, 질소 함량에 따른 기계적 특성 및 피로균열성장 연구는 매우 미비하다. 따라서 본 연구에서는 탄소와 질소의 함량에 따른 기계적거동을 평가하고, 이에 따른 피로균열전파속도를 관찰하여 스테인리스강의 정확한 피로균열전파속도 곡선을 제시하고자 한다. 실험에 사용된 시편은 두께 5mm, 폭 25.4mm CT시편을 사용하였으며, 1mm의 예비균열을 주었다. 그리고 실험온도는 상온과 원전가동온도인 $316^{\circ}C$에서 실시하였으며, 주파수는 10Hz를 주었다. 실험결과 각 함량에 따른 type 347의 미세조직 관찰결과 기지내에 압연방향을 따라 조대한 석출물의 흐름이 관찰되었으며, 크기나 분포가 큰 차이를 보였다. C+N 함량이 낮은 시편은 주로 $0.1\;{\mu}m$ 이하의 미세한 입자들이 오스테나이트 기지조직의 입내와 입계에 고르게 분포되어 있었다. 그러나 C+N 함량이 높은 시편의 경우에는 $0.1\;{\mu}m$ 이하의 미세한 입자들과 함께 국부적으로 $1\sim10\;{\mu}m$의 조대한 입자들이 분포하고 있는 것이 관찰되었다. 그리고 질소의 함량이 높아짐에 따라 인장강도는 증가하였으며, 피로시험결과 고온에서 실험한 피로균열성장률 곡선이 상온보다 높게 나타남을 확인할 수 있었다. 그리고 질소가 적게 첨가되고 탄소의 함량이 많을수록 피로균열성장률은 ASME 곡선보다 낮게 나타났다.

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A 9 mW Highly-Digitized 802.15.4 Receiver Using Bandpass ∑Δ ADC and IF Level Detection

  • Kwon, Yong-Il;Park, Ta-Joon;Lee, Hai-Young
    • Journal of electromagnetic engineering and science
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    • v.8 no.2
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    • pp.76-83
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    • 2008
  • A low power(9 mW) highly-digitized 2.4 GHz receiver for sensor network applications(IEEE 802.15.4 LR-WPAN) is realized by a $0.18{\mu}m$ CMOS process. We adopted a novel receiver architecture adding an intermediate frequency (IF) level detection scheme to a low-power complex fifth-order continuous-time(CT) bandpass L:tl modulator in order to digitalize the receiver. By the continuous-time bandpass architecture, the proposed $\Sigma\Delta$ modulator requires no additional anti-aliasing filter in front of the modulator. Using the IF detector, the achieved dynamic range(DR) of the over-all system is 95 dB at a sampling rate of 64 MHz. This modulator has a bandwidth of 2 MHz centered at 2 MHz. The power consumption of this receiver is 9.0 mW with a 1.8 V power supply.

수소화물의 파괴가 압력관 재료들의 파괴인성에 미치는 영향

  • 오제용;김인섭;김영석
    • Proceedings of the Korean Nuclear Society Conference
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    • 1998.05b
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    • pp.105-110
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    • 1998
  • 본 연구에서는 수소화물의 파괴가 일어나는 조건과 수소화물의 파괴가 압력관 재료의 파괴인성에 미치는 영향에 대하여 알아보았다. 사용된 재료들은 상용 캐나다 압력관 재료와 러시아에서 개발된 E635, El25라는 재료로서 균열진전방향이 압력관의 축방향을 향하도록 CT 시편을 제작하여 파괴시험을 하였다 상온에서 파괴인성은 캐나다 압력관재료, El25, E635의 순서로 크게 나왔다. 100ppm의 수소를 장입한 경우 상온에서의 파괴인성은 크게 감소하여 세 재료들 모두 비슷한 평평한 J-R 커브를 보였으며, 캐나다 재료와 E63S의 파면에서 관찰되는 fissure의 간격은 150~200$\mu\textrm{m}$로 수소화물의 간격과 비슷하였으며 tunnelling 현상이 일어났다. El2S는 불규칙한 짧은 fissure들이 관찰되었다. 20$0^{\circ}C$에서는 수소화물의 파괴에 의한 fissure들이 관찰되지 않았으며 수소화물이 파괴인성에 영향을 미치지 않는 것으로 나타났다. El25는 상온과 20$0^{\circ}C$에서의 J-R커브가 비슷하게 나타났다.

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Analysis of Lightning Current Distribution for Reducing the Conductive EMI in a Structure (도전성 EMI 저감을 위한 구조체의 뇌격전류 분류율 분석)

  • Cho, Sung-Chul;Lee, Tae-Hyung;Eom, Ju-Hong;Lee, Bok-Hee
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.1630-1631
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    • 2011
  • Lightning current distribution in a building directly hit was studied by using a scaled steel frame structure model. As the test current source, impulse current with the rise time of 10 ${\mu}s$ and sinusoidal current with the frequency of 30 kHz were used to confirm the validity of test results. The current distributions at both horizontal and vertical pillars were measured by using CT. From the test results, the reduction effect for the conductive EMI was verified and a design method reducing the conductive EMI was proposed.

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Design of a Remote Automatic Earth Tester at Electric Pole in a Distribution Line (배전선로 변대주 원격자동 접지측정장치 설계)

  • Yoon, Gi-Gab;Yoon, Suk-Mu;Lee, Seung-Hak;Kim, Hong-Pil;Choi, Sang-Joon
    • Proceedings of the KIEE Conference
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    • 2000.07a
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    • pp.498-500
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    • 2000
  • Generally, the earth resistance of distribution lines are measured under the condition of the climbing pole. This paper proposed the design technique of a new concept type remotoe automatic measuring system without climbing electric distribution poles. The worker on the earth under pole, can measure by using the CT on the located at the top of COS operating Stick. The system is useful for safety of worker, and saving mans, times for measuring.

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The elastic and plastic behaviour of the micro-FE models for vertebral trabecular bones (척추 해면골에 대한 미세 유한요소모델의 탄성 및 소성특성에 관한 연구)

  • 우대곤;김한성;원예연;백명현;탁계래
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.1320-1323
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    • 2003
  • In this study, the micro-FE analyses were carried out for the plastic behaviour of vertebral trabecular bones. Many researchers have investigated the elastic behaviour of trabecular bones by using the micro-finite element models based on the micro-CT images. However, there was no micro-FE model to account for the plastic behaviour of trabecular bones. Ulrich et at. reported that best results at coarser model were obtained when using 'compensated hexahedron models' with the same relative density. This study indicates that, for the elastic and plastic analysis, 'the compensated hexahedron FE model' is likely to be limited to about 63$\mu\textrm{m}$ image resolution in the vertebra trabecular bones.

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