• 한국한의학연구원논문집
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• 제2권1호
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• pp.177-191
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• 1996

Chunggansan(淸肝散) was tested for the effects on detoxication mechanism of alcohol. Chunggansan was treated firstly into samples, and then ethanol intoxicated animal models were set with them. In vitro, the level of lipid peroxide in tissue of liver proportionally decreased with the level of concentration of extract prepared from Chunggansan. In vivo, after the extract was administered to the animal model for seven days, the level of lipid peroxide in liver dependently decreased in proportion of concentration. The glutathione percentage purposely induced acute ethanol intoxicated samples, followed by Chunggansan pre-medicating administration, increased in compare with the group treated with only ethanol. Also, the enzyme activities of ALT, AST, and ${gamma}-GTP$ in liver decreased.

• 설비공학논문집
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• 제19권7호
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• pp.500-511
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• 2007

The Optimal solutions of the design variables in internally finned tubes have been obtained for three-dimensional periodically fully developed turbulent flow and heat transfer. For a trapezoidal fin profile, performances of the heat exchanger are determined by considering the heat transfer rate and pressure drop, simultaneously, that are interdependent quantities. Therefore, Pareto frontier sets of a heat exchanger can be acquired by integrating CFD and a multi-objective optimization technique. The optimal values of fin widths $(d_1,\;d_2)$, fin height(h) and helix angle$(\gamma)$ are numerical1y obtained by minimizing the pressure loss and maximizing the heat transfer rate within ranges of $d_1=0.5\sim1.5mm$, $d_2=0.5\sim1.5mm$, $h=0.5\sim1.5mm$, and $\gamma=0\sim20^{\circ}$. For this, a general CFD code and a global genetic algorithm(GA) are used. The Pareto sets of the optimal solutions can be acquired after $30^{th}$ generation.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 추계학술대회 논문집 전기물성,응용부문
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• pp.147-149
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• 2002

Recently, the study on development of electrical and electronic device is done to set miniature, high degrees of integration and efficiency by using inorganic materials the study of Langmuir-Boldgett(LB) method that uses organic materials because of the limitation for the ultrasmall size. The structure of MIM(Metal-Insulator-Metal) device is Cr-Au/PBLG/ Al. the number of accumulated layers are 1, 3, 5, 7, 9. The I-V characteristic of the device is measured from 0[V] to 2[V] and the characteristic of current-time of the devices. We have investigated the capacitance because PBLG system have a accumulated layers the maximum value of measured current is increased as the number of accumulated layers are decreased. The capacitor properties of a thin film is better as the distance between electrodes is smaller. The results have shown the insulating materials and could control the conductivity by accumulated layers.

• Geomechanics and Engineering
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• 제6권2호
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• pp.99-115
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• 2014

Uncertainties in design variables and design equations have a significant impact on the safety of geotechnical structures like retaining walls and slopes. This paper presents a possible framework for obtaining the partial safety factors based on reliability approach for different random variables affecting the stability of a reinforced concrete cantilever retaining wall and a slope under static loading conditions. Reliability analysis is carried out by Mean First Order Second Moment Method, Point Estimate Method, Monte Carlo Simulation and Response Surface Methodology. A target reliability index ${\beta}$ = 3 is set and partial safety factors for each random variable are calculated based on different coefficient of variations of the random variables. The study shows that although deterministic analysis reveals a safety factor greater than 1.5 which is considered to be safe in conventional approach, reliability analysis indicates quite high failure probability due to variation of soil properties. The results also reveal that a higher factor of safety is required for internal friction angle ${\varphi}$, while almost negligible values of safety factors are required for soil unit weight ${\gamma}$ in case of cantilever retaining wall and soil unit weight ${\gamma}$ and cohesion c in case of slope. Importance of partial safety factors is shown by analyzing two simple geotechnical structures. However, it can be applied for any complex system to achieve economization.

• Current Optics and Photonics
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• 제2권6호
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• pp.576-581
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• 2018

A new approach for identification of a microwave frequency using an integrated optical waveguide chip, combined with a phase modulator (PM) and two microring resonators (MRRs), is proposed, theoretically deduced, and verified. By wavelength tuning to set the PM under the condition of a double side band (DSB), the measurement range can be started from the dc component, and the measurement range and response slope can be adjusted by designing the radius and transmission coefficient of the MRR. Simulations reveal that the amplitude comparison function (ACF) has a monotonic relationship from dc to 32.5 GHz, with a response slope of 5.15 dB under conditions of DSB modulation, when the radius values, transmission coefficients, and the loss factors are designed respectively as $R_1=400{\mu}m$, $R_2=600{\mu}m$, $t_1=t_2=0.63$, and ${\gamma}_1={\gamma}_2=0.66$. Theoretical calculations and simulation results both indicate that this new approach has the potential to be used for measuring microwave frequencies, with the advantages of compact structure and superior reconfigurability.

• Nuclear Engineering and Technology
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• 제50권7호
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• pp.1154-1159
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• 2018

Precise prediction of the radiation interaction position in scintillators plays an important role in medical and industrial imaging systems. In this research, the incident position of the gamma rays was predicted precisely in a plastic rod scintillator by using attenuation technique and multilayer perceptron (MLP) neural network, for the first time. Also, this procedure was performed using nonlinear regression (NLR) method. The experimental setup is comprised of a plastic rod scintillator (BC400) coupled with two PMTs at two sides, a $^{60}Co$ gamma source and two counters that record count rates. Using two proposed techniques (ANN and NLR), the radiation interaction position was predicted in a plastic rod scintillator with a mean relative error percentage less than 4.6% and 14.6%, respectively. The mean absolute error was measured less than 2.5 and 5.5. The correlation coefficient was calculated 0.998 and 0.984, respectively. Also, the ANN technique was confirmed by leave-one-out (LOO) method with 1% error. These results presented the superiority of the ANN method in comparison with NLR and the other methods. The technique and set up used are simpler and faster than other the previous position sensitive detectors. Thus, the time, cost and shielding and electronics requirements are minimized and optimized.

• Nuclear Engineering and Technology
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• 제54권11호
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• pp.4084-4094
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• 2022

The Advanced Fuels Campaign Fission Accelerated Steady-state Test (FAST) at Idaho National Laboratory (INL) completed its first irradiation cycle within the Advanced Test Reactor (ATR). The test focused on the irradiation of alloy fuel forms for use in sodium fast reactors. The first cycle of FAST testing was completed and four rodlets were removed for the initial post irradiation examination (PIE). The rodlet design and irradiation conditions were evaluated using Monte Carlo N-Particle (MCNP) for as-run power history and COMSOL for temperature analysis. These rodlets include a set of low burnups (~2.5 % fissions per initial metal atoms [%FIMA]), control rodlets, and a helium-bonded annular rodlet (4.7 %FIMA). Nondestructive PIE has been completed and includes visual inspection, neutron radiography and gamma scanning of the FAST capsules and rodlets. Radiography confirmed the integrity of the experiments, revealed that the annulus in the annular fuel was filled at a modest burnup (4.7 %FIMA), and indicated potential slumping of the cooler rodlets at lower burnup. Precision gamma scanning indicated mostly usual fission product behavior, except for cesium in the He-bonded annular fuel. Future destructive PIE will be necessary to fully interpret the effects of accelerated irradiation on U-Zr metallic fuel behavior.

• Nuclear Engineering and Technology
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• 제55권10호
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• pp.3700-3708
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• 2023

The stochastic origin ensembles method with resolution recovery (SOE-RR) has been proposed to reconstruct proton-induced prompt gammas (PGs), and the reconstructed PG image was used for range verification. However, due to low detection efficiency, the number of valid events is low. Such a low-count condition can degrade the accuracy of the SOE-RR method for proton range verification. In this study, we proposed two strategies to improve the reconstruction of the SOE-RR algorithm for low-count PG imaging. We also studied the number of iterations and repetitions required to achieve reliable range verification. We simulated a proton beam (10⁸ protons) irradiated on a water phantom and used a two-layer Compton camera to detect 4.44-MeV PGs. Our simulated results show that combining the SOE-RR algorithm with restricted volume (SOE-RR-RV) can reduce the error of the estimation of the Bragg peak position from 5.0 mm to 2.5 mm. We also found that the SOE-RR-RV algorithm initialized using a back-projection image could improve the convergence rate while maintaining accurate range verification. Finally, we observed that the improved SOE-RR algorithm set for 60,000 iterations and 25 repetitions could provide reliable PG images. Based on the proposed reconstruction strategies, the SOE-RR algorithm has the potential to achieve a positioning error of 2.5 mm for low-count PG imaging.

• 한방안이비인후피부과학회지
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• 제21권3호
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• pp.10-19
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• 2008

Objective : To investigate the effects of Radix Ophiopogon japonieus on atopic dermatitis, I prepared DNCB(2,4-dinitrochlorobenzen) induced atopic dermatitis NC/Nga mice and observed the mice by four ways; eye observation, the number of skin behavior times, histological changes of skin and cytokine(Total IgE, IL-4, $IFN-{\gamma}$). Methods : After prepare Radix Ophiopogon japonicus extract, DNCB induced atopic dermatitis NC/Nga mice were divided into three groups. The first is Control group which was intact group. The second is Medication group which was orally medicated Radix Ophiopogon japonicus extract one time a day for consecutive 5 days. The third group is Application group which was applied Radix Ophiopogon japonicus extract externally one time a day for consecutive 5 days. After that, the effect of Radix Ophiopogon japonicus on atopic dermatitis was observed. Statistical analysis was performed by using Kmskal-Wallis test and statistical significance was set at less than 5%. Results : 1. Radix Ophiopogon japonicus showed some in both Medication group and Application At observation of skin morphologic change, effects to prevent erythema reaction on skin group. 2. At the number of scratching behavior times, Radix Ophiopogon japonicus showed an effect to decrease scratching behavior times, but there was no statistical significance among three groups. 3. At skin tissue H-E stain, Radix Ophiopogon japonicus showed an effect to prevent skin epidermal tissue damages and also showed that it could keep the skin healthy in both Medication group and Application group. Especially in Application group, the skin of mouse showed almost normal recovery. 4. At cytokines, there was no statistical significance among three groups in IgE and IL-4. But Radix Ophiopogon japonicus showed an significant effect to suppress $IFN-{\gamma}$ in both Medication group and Application group. There was no significant difference between two groups. Conclusion : Radix Ophiopogon japonicus has some effects on atopic dermatitis in both internal medication and external application.

• 한국항해항만학회지
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• 제40권5호
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• pp.241-247
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• 2016

The tracking filter plays a key role in the accurate estimation and prediction of maneuvering a vessel's position and velocity when attempting to enhance safety by avoiding collision. Therefore, in order to achieve accurate estimation and prediction, many oceangoing vessels are equipped with the Automatic Radar Plotting Aid (ARPA) system. However, the accuracy of prediction depends on the tracking filter's ability to reduce noise and maintain a stable transient response. The purpose of this paper is to derive the optimal values of the gain parameters used in tracking a High Dynamic Warship. The algorithm employs a ${\alpha}-{\beta}-{\gamma}$ filter to provide accurate estimates and updates of the state variables, that is, positions, velocity and acceleration of the high dynamic warship based on previously observed values. In this study, the filtering coefficients ${\alpha}$, ${\beta}$ and ${\gamma}$ are determined from set values of the damping parameter, ${\xi}$. Optimization of the damping parameter, ${\xi}$, is achieved experimentally by plotting the residual error against different values of the damping parameter to determine the least value of the damping parameter that results in the optimum smoothing coefficients leading to a reduction in the noise corruption effect. Further investigation of the performance of the filter indicates that optimal smoothing coefficients depend on the initial and average velocity of the target.