• 생약학회지
• /
• 제18권3호
• /
• pp.168-176
• /
• 1987

Veronicastrum sibiricum (L.) Pennell (Scrophulariaceae) is a perennial herb growing in moist land. It has been used as a korean folk medicine in treating common cold, leucorrhea, cystitis and liver damage and as cholagogue. The present study dealt with the elucidation of the chemical components. From the roots of the plant, five iridoids were isolated and identified as minecoside $(mp\;142{\sim}3^{\circ})$, 6-O-veratryl catalpol ester $(mp\;216{\sim}8^{\circ})$, catalpol $(mp\;204{\sim}6^{\circ})$, aucubin $(mp\;180{\sim}2^{\circ})$ and 6-desoxy-8-isoferuloyl harpagide $(mp\;139{\sim}41^{\circ})$. Furthermore, ${\beta}-sitosteryl-3-O-D-glucoside$, campesteryl 3-O-D-glucoside, ${\beta}-sitosterol$, campesterol, stigmasterol and mannitol were also isolated.

• 한국자원식물학회지
• /
• 제14권1호
• /
• pp.8-14
• /
• 2001

역병균 (Phytophthora infestans)의 균사 신장 및 난포자 형성에 미치는 생리 화학적 영향을 알아보고자 국내에서 분리된 $A^2$형인 KM10, U6, MHB6, CDB6, JD1과 일본에서 분양 받은 $A^1$형인 F8l7, DNC303, $A^2$ 형인 IB908, DN107 균주를 이용하여 공시 배지별 및 V-8A 배지에 cholesterol, $\beta$-sitosterol및 lecithin을 첨가했을 때의 영향을 조사하고, 식물체상에서의 난포자 형성여부를 조사한 결과, 다음과 같은 결과를 얻을 수 있었다. 1. 균사 신장은 V-8A, RMA에서 양호하였고, 난포자 형성은 V-8A에서 가장 많았다. V-8A에 cholesterol, $\beta$-sitosterol 및 lecithin을 첨가하였을 때 접종 10일 후 균사 신장은 무처리 대비 각각 16.6, 8.3, 5.2% 더 신장하였으며, 난포자 형성수는 각각 76.0, 58.0, 34.6% 크게 증가하였다. 2. $A^1$형과 $A^2$형이 동시에 존재할 경우 식물체상에서 난포자를 형성하는지 알아보고자 식물체 조직편에 $A^1$, $A^2$형을 대치 배양하여 난포자 형성을 유도한 결과, 난포자의 형성률 및 수는 적었으나, 식물체 상에서도 난포자 형성이 가능한 것을 확인 할 수 있었는데, 금후 이에 대한 세심한 주의가 필요할 것으로 생각된다.

• Natural Product Sciences
• /
• 제1권1호
• /
• pp.55-60
• /
• 1995

In the course of evaluation of hepatoprotective components against alcohol-induced toxicity from Aloe spp., the methanol extract was found to cause a significant inhibition of rat liver cytosolic alcohol dehydrogenase activity. Systematic fractionation of active tractions monitored by bioassay led to isolation of four compounds; aloe-emodin, aloenin, ethylidene-aloenin and ${\beta}-sitosterol$, which were estimated as active principles for inhibition of c-ADH and c-ALDH activities in vitro.

• Natural Product Sciences
• /
• 제10권2호
• /
• pp.69-73
• /
• 2004

Continuation of a phytochemical study of Cichorium intybus L. (Astraceae) growing in Egypt, resulted in the isolation and identification of a new sesquiterpene lactone 3,4-dihydrolactucin, in addition to the eight known compounds; kaempferol, isoscutellarin, cichoriin, umbelliferone, lupeol, lupeol acetate, ${\beta}-sitosterol$, and ${\beta}-sitosterol-3-O-glucoside$. Chemical structures of the isolated compounds were assigned based on different physical, chemical, and spectroscopic techniques including IR, UV, MS, 1D- and 2D-NMR spectra. Furthermore, the antimicrobial, and spasmogenic activities of some fractions and isolates were also assessed.

• Natural Product Sciences
• /
• 제19권2호
• /
• pp.137-144
• /
• 2013

Phytochemical constituents were isolated from the seeds of tartary buckwheat (Fagopyrum tataricum) by open column chromatography. Their structures were elucidated as ${\beta}$-sitosterol (1), ${\beta}$-sitosterol-3-O-glucoside (2), oleanolic acid (3), kaempferol (4), quercetin (5), kaempferol-3-O-rutinoside (6), and quercetin-3-O-rutinoside (7) on the basis of spectroscopic analysis including $^1H$-, $^{13}C$-NMR, and MS. To our knowledge, oleanolic acid (3) has been isolated for the first time from the seeds of Fagopyrum species. The total contents of compounds 4 - 7 were 0.500 mg/g in Daesan maemil, 0.312 mg/g in Yangjul maemil, and 2.185 mg/g in tartary buckwheat.

• 한국약용작물학회:학술대회논문집
• /
• 한국약용작물학회 2011년도 춘계학술발표회
• /
• pp.382-383
• /
• 2011

• 생약학회지
• /
• 제31권1호
• /
• pp.1-6
• /
• 2000

Five compounds were isolated from the methanol extract of the tubers of Cyperus rotundus (Cyperaceae). They were identified as cyperol(1), ${\alpha}-cyperone(2)$, cyperotundone(3), sugetriol triacetate(4) and ${\beta}-sitosterol(5)$ on the basis of spectroscopic and physicochemical analysis. Among them, cyperol, ${\alpha}-cyperone$ and cyperotundone were shown inhibitroy effects on LPS-induced nitric oxide production in RAW 264.7 cells in a dose dependent manner.

• 생약학회지
• /
• 제18권3호
• /
• pp.180-183
• /
• 1987

Pericarp of Zanthoxylum coreanum Nakai have been used as a crude medicine for the treatment of ozena, rheumatoid, nasal sinusitis, meno-xenia, dyspepsia, toothache, sore throat, pains in the limbs, etc. in Korea. A sterol fraction and two compounds, compound I and II were isolated from the roots, stems, leaves of Zanthoxylum coreanum Nakai. The sterol fraction was identified as a mixture of ${\beta}-sitosterol$ and campesterol. Compound I, colorless prismatic crystals, $C_{13]H_{13}NO_4$, mp. $175{\sim}177^{\circ}$, was proved to be skimmianine which is one of the alkaloids and compound II, $C_{14}H_{28}O_2$, mp. $53{\sim}55^{\circ}$, white powdered crystals was identified as myristic acid.

• 생약학회지
• /
• 제19권4호
• /
• pp.233-238
• /
• 1988

Angelica flaccida Kom. is a herbal plant growing wild in the marsh of valley in Korea. It has been used for sedative and analgesic as a folk medicine, but its constituents have not been clarified yet. Five known coumarins such as isoimperatorin, decursidin, (-) anomalin, decursin, decursinol and two sterols such as ${\beta}-sitosterol$ and stigmasterol were isolated from the root of this plant, Their structures were identified by the UV, IR, NMR, mass data and the physico-chemical properties.

• 생약학회지
• /
• 제33권4호통권131호
• /
• pp.267-271
• /
• 2002

Prunasin and pomolic acid together with a mixture of ursolic and oleanolic acids, (-)-epicatechin and ${\beta}-sitosterol$ glucoside were isolated from the roots of Chaenomeles japonica. Among these compounds, the isolation of pomolic acid and prunasin is the first report from the genus Chaenomeles.