• The Journal of Korean Society for Radiation Therapy
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• v.4 no.1
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• pp.71-77
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• 1990

The present study was undertaken to investigate effects of ionizing radiation on DNA synthesis and chromosomal abnormality in cultured submandibular gland(SG) cells. SG cells from C57BL/6N Crj mice were cultured in Dulbecco's modified Eagle's medium (DME) supplemented with $10\%$ fetal bovine serum, antibiotics and fungizone. The cultured SG cells were irradiated with graded doses of gamma ray ($^{60}Co$) at a dose rate of 58.4rad/min. The effect of irradiation of $^{60}Co$ on DNA synthesis in cultured cells was evaluated by measuring the incorporation of 3H-TdR. Using conventional chromosome techniques and Giemsa staining methods, chromosomal abnormalities in cultured SG cells, induced by irradiation of $^{60}Co$ werw examined. Cytological observations were carried out by a light microscope with high resolving power. The results obtained were as follows : 1. DNA synthesis of SG cells was quantitatively dependent on a radiation dose compare to control. 2. A polyploids and few chromosome-type break, such as single and double breaks, deltions and triradial figures were more predominantly in irradiated SG cells than in control. This increase of chromosomal abnormality was in the proposition to the irradiation doses.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.12
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• pp.2310-2316
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• 2016

We studied the effect of $Co^{60}$ gamma-radiation on the fiber Bragg gratings (FBGs) by irradiation time of UV Krypton fluoride (KrF) excimer laser among grating processing parameters. The FBGs were fabricated in a different UV laser irradiation time at 30, 60, 90, and 120 seconds using the same commercial Ge-doped silica core fiber (SMF-28e). It was exposed to gamma-radiation up to a high dose of 34.3 kGy at the dose rate of 106 Gy/min, and then it was analyzed radiation effects by measuring the radiation-induced change in the temperature sensitivity coefficient and Bragg wavelength shift. According to the experimental results, We confirmed that the UV laser irradiation period for grating inscription has a highly effect on the radiation sensitivity of the FBGs. The radiation-induced Bragg wavelength shift by the change of laser irradiation conditions showed a difference more than about 50 %.

• Plant Biotechnology Reports
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• v.3 no.3
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• pp.191-197
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• 2009

Four-leaf white clover is not found easily in nature due to its low appearance rate (1 in 10,000). Because people believe that it brings good luck and like to either keep it or present it to a loved one, it has commercial and ornamental value. To breed four-leaf clover, we exposed its flowers to ${\gamma}-rays$ at the pollination stage. The $M_1$ seeds produced following doses at 25-100 Gy showed an approximately 74% germination rate, with seedling survival at 46%. In the $M_1$ generation of plants irradiated within that dose range, we found an increased frequency of four leaflets. One of them, Jeju Lucky-1 (JL-1), had a frequency of about 60%. To see whether that mutation was somaclonal or genetic, we observed its $M_2$ generation and found that such a phenotype reappeared. Although our results demonstrated that the irradiation of fully mature flowers led to a higher frequency of 4-leaflets, we could not clearly explain the genetic mechanism involved. We suggest that JL-1 is valuable as a new variety, without further genetic fixation, because white clover can be propagated vegetatively by stolons.

• Macromolecular Research
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• v.16 no.2
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• pp.139-148
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• 2008

Biodegradable and elastic poly(L-lactide-co-$\varepsilon$-caprolactone) (PLCL) was electrospun to prepare nanofibers, and N-isopropylacrylamide (NIPAAm) was then grafted onto their surfaces under aqueous conditions using $^{60}Co-{\gamma}$ irradiation. The graft yield increased with increasing irradiation dose from 5 to 10 kGy and the nanofibers showed a greater graft yield compared with the firms. SEM confirmed that the PLCL nanofibers maintained an interconnected pore structure after grafting with NIPAAm. However, overdoses of irradiation led to the excessive formation of homopolymer gels on the surface of thc PLCL nanofibers. The equilibrium swelling and deswelling ratio of the PNIPAAm-g-PLCL nanofibers (prepared with 10 kGy) was the highest among the samples, which was consistent with the graft yield results. The phase-separation characteristics of PNIPAAm in aqueous conditions conferred a unique temperature-responsive swelling behavior of PNIPAAm-g-PLCL nanofibers, showing the ability to absorb a large amount of water at < $32^{\circ}C$, and abrupt collapse when the temperature was increased to $40^{\circ}C$. In accordance with the temperature-dependent changes in swelling behavior, the release rate of indomethacin and FITC-BSA loaded in PNIPAAm-g-PLCL nanofibers by a diffusion-mediated process was regulated by the change in temperature. Both model drugs demonstrated greater release rate at $40^{\circ}C$ relative to that at $25^{\circ}C$. This approach of the temperature-controlled release of drugs from PNIPAAm-g-PLCL nanofibers using gamma-ray irradiation may be used to design drugs and protein delivery carriers in various biomedical applications.

• Nuclear Engineering and Technology
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• v.7 no.4
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• pp.285-293
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• 1975

A result of the study to determine the depth-dose distribution along the central axis of a polyethylene sphere in diameter of 30cm is described. Depth-dose distribution in the polyethylene sphere for broad beam of monoenergetic photons has been experimentally determined with thermoluminescent dosimeter as a cavity dosimeter. The conversion of dose absorbed in the LiF TLD to dose in the surrounding medium was carried out on the basis of Burlin's generalized cavity theory. Presented in graphical forms are the results obtained. The maximum absorbed doses in the sphere were observed at the depth of about 0.3cm and 0.5cm from the surface of the sphere for the gamma-rays of $^{137}$ Cs and $^{60}$ Co, respectively.

• Radiation Oncology Journal
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• v.1 no.1
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• pp.21-24
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• 1983

The thickness of the part being irradiated is finite. Percent depth dose tables being used routinely are generally obtained from dosimetry in a phantom much thickner than usual patient. At or close to exit surface, the dose should be less than that obtained from the percent depth dose tables, because of insufficient volume for backscattering. To know the difference between the true absorbed dose and the dose obtained from percent depth dose table, the doses at or close to the exit surface were measured with plate type ionization chamber with volume of 0.5ml. The results are as follows; 1. In the case of $^{60}Co$, percent depth dose at a given depth increases with underlying phantom thickness up to the 5cm. 2. In the case of $^{60}Co$, the dose correction factor at exit surface which is less than 1, increases with part thickness and decreases with field size. 3. Exposure time may not be corrected when the part above 10cm in thickness is treated by $^{60}Co$. 4. In the case of 10MV x-ray, the dose correction factor is nearly 1 and constant for the underlying phantom thickness and field size, so the correction of monitor unit is not necessary for part thickness.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7521-7526
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• 2014

Radioprotective effects of amentoflavone were investigated by examining cell viability, apoptosis, cell cycling concentrations of intracellular ROS (reactive oxygen species), and relative mitochondrial mass by flow cytometry after $^{60}Co$ irradiation. Pretreatment with amentoflavone 24 hours prior to 8 Gy $^{60}Co$ ${\gamma}$-ray irradiation significantly inhibited apoptosis, promoted the G2 phase, decreased the concentration of ROS and mitochondrial mass. These results collectively indicate that amentoflavone is an effective radioprotective agent.

• 전기의세계
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• v.20 no.3
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• pp.27-31
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• 1971

The main focus of this paper is on the study of the radiation effect upon the electrical property of a A-Kind insulator which is one of the organic insulators. The varnished cloth is so typical of the A-Kind insulators as to be selected for a sample. AC and Impluse voltage is applied to the variable Gamma ray irradiated dose samples with the constant time duration and the dielectric breakdown voltage are measured from the sample. The experimental data of the dielectric breakdown voltage are considerably decreased. The above conclusion is useful for the selection and application of the orgainc insulators under the irradiation effects.

• Nuclear Engineering and Technology
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• v.4 no.2
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• pp.90-101
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• 1972

Radiation grafting of acrylic acid to Polyester fabric has been studied by an impregnation method to render its surface more hydrophilic. Impregnated fabric was irradiated under nitrogen with gamma-ray from Co-60. The homopolymer formed usually could be extracted with water at 10$0^{\circ}C$. Graft-fabric exhibited a good acceptability to acid, basic or disperse dyes in conventional aqueous dye bath at moderate temperature.

• Nuclear Engineering and Technology
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• v.50 no.6
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• pp.957-962
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• 2018

The gamma radiation shielding capability (GRSC) of two clay-materials (Ball clay and Kaolin)of Southwestern Nigeria ($7.49^{\circ}N$, $4.55^{\circ}E$) have been investigated by determine theoretically and experimentally the mass attenuation coefficient, ${\mu}/{\rho}(cm^2g^{-1})$ of the clay materials at photon energies of 609.31, 1120.29, 1173.20, 1238.11, 1332.50 and 1764.49 keV emitted from $^{214}Bi$ ore and $^{60}Co$ point source. The mass attenuation coefficients were theoretically evaluated using the elemental compositions of the clay-materials obtained by Particle-Induced X-ray Emission (PIXE) elemental analysis technique as input data for WinXCom software. While gamma ray transmission experiment using Hyper Pure Germanium (HPGe) spectrometer detector to experimentally determine the mass attenuation coefficients, ${\mu}/{\rho}(cm^2g^{-1})$ of the samples. The experimental results are in good agreement with the theoretical calculations of WinXCom software. Linear attenuation coefficient (${\mu}$), half value layer (HVL) and mean free path (MFP) were also evaluated using the obtained ${\mu}/{\rho}$ values for the investigated samples. The GRSC of the selected clay-materials have been compared with other studied shielding materials. The cognizance of various factors such as availability, thermo-chemical stability and water retaining ability by the clay-samples can be analyzed for efficacy of the material for their GRSC.