• Title/Summary/Keyword: $^{15}N$ recovery

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Nitric Oxide Impairs the Recovery from Hemorrhagic Hypotension in Conscious Rats

  • Park, Yoon-Yub;Lee, Young-Man
    • The Korean Journal of Physiology and Pharmacology
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    • v.2 no.3
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    • pp.345-351
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    • 1998
  • The role of nitric oxide (NO) in the hemorrhagic hypotension was examined using a NO synthase inhibitor, $N^{\omega}-nitro-L-arginine$ methyl ester (L-NAME), in conscious rats. The rats were bled at a constant rate (2 ml/kg/min) through a femoral arterial catheter until the mean arterial pressure (MAP) was reduced by 50 mmHg. We studied the responses to hemorrhage under normal condition (Control) and after the pretreatment with 3 doses of L-NAME (1.6, 8, 40 mg/kg i.v. of NOX1.6, NOX8, and NOX40, respectively). Intravenous bolus injection of L-NAME produced a sustained increase in MAP and decrease in heart rate (HR). During hemorrhage, the MAP fell faster in the NOX8 and NOX40-treated groups than in Control group, but the control group showed same response to NOX1.6. HR greatly increased in NOX groups. The recovery from hemorrhagic hypotension was slowed in the control group, which was not treated with L-NAME. In comparison with the control group, NOX8 and NOX1.6-treated groups registered a significant recovery in MAP during the 15 min recovery period, but NOX40 brought about only a slight increase in MAP. NO precursor, L-arginine (150 mg/kg i.v.), produced significant bradycardic responses before and after hemorrhage and significant depressor response only after hemorrhagic hypotension regardless of pretreatment with L-NAME. These data suggest that the role of NO in blood pressure regulation is greater after hemorrhagic hypotension than basal condition, but the effect of NO can be detrimental to the recovery from hemorrhagic hypotension. In addition, the bradycardic response of L-arginine provides indirect evidence that NO may inhibit sympathetic activity, especially after hemorrhagic hypotension.

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Comparison of Recovery Rate and Fatty Acid Composition of Dried Sea Cucumbers Apostichopus japonicus Dried by Hybrid Heat Pump Decompression and by Hot Air (2종류의 건조기로 제조한 돌기해삼(Apostichopus japonicus)의 복원율과 지방산조성 비교)

  • Jeong, U-Cheol;Jin, Feng;Anisuzzaman, Md;Choi, Byeong-Dae;Jung, Hyun-Chol;Lee, Sang-Ro;Kang, Seok-Joong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.52 no.3
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    • pp.232-240
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    • 2019
  • Approximately 80% of the world's sea cucumbers Apostichopus japonicas are processed into dried sea cucumbers. The hot air-drying method is currently used in industry, but it has many problems, such as a short drying time, severe browning, high nutrition loss, and low recovery. In this study, the moisture absorption rate, dry recovery rate, and lipid nutrient composition of sea cucumber dried by heat pump decompression and with a hybrid dryer were investigated. The moisture absorption rates for hybrid-dried sea cucumbers at 24, 48, 72, 96, and 120 h were 241.3%, 427.7%, 652.0%, 721.0%, and 742.2%, respectively. The moisture absorption rates for hot air-dried sea cucumbers were 155.8%, 240.0%, 390.3%, 655.5%, and 667.4%, respectively. Thus, moisture absorption was faster and greater with hybrid drying than with hot air drying. The dry recovery rate at 24 h was greater for hybrid-dried sea cucumber (70.7%) than for hot air-dried sea cucumber (59.8%). Saturated fatty acid contents of the hybrid- and hot air-dried sea cucumbers were 30.0% and 37.5%, respectively. Moreover, greater ${\Sigma}n-3$ polyunsaturated fatty acid content was found in hybrid-dried sea cucumber (15.8%) than in hot air-dried sea cucumber (11.7%).

The Change of the Important Blood Factors According to the Recovery of Motor Function with Ischemic Stroke Patients (허혈성 뇌졸중 환자의 운동기능회복에 따른 중요 혈액인자들의 변화)

  • Kim, Myung-Chul
    • Journal of Korean Physical Therapy Science
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    • v.15 no.2
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    • pp.1-13
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    • 2008
  • Background: This study had been carried out with 18 ischemic stroke patients as its object for about eight months from October, 2006 to May, 2007 in order to observe the recovery of motor function and the change of important blood factors according to the different quantitative exercises. Methods: Subjects were assigned randomly either experimental group (n=19) or the control group (n=19), when the study began the halfway on this study dropout 20 patients, and final subjects remained experimental group's 9 patients and control group's 9 patients. Both groups received thermotherapy and functional electrical stimulation (FES), also taken different quantitative exercise therapy (experimental group 180 minutes, control group 80 minutes). Subjects were assessed for upper and lower extremities motor function Fugl-Meyer Scale; FMS), blood test (white blood count; WBC, low density lipoprotein -cholesterol; LDL-C, high density lipoprotein-cholesterol; HDL-C, Troponin) during pretest, after 2 months, after 3 months. Results: The results of this study were as follows; 1. FMS has no statistically significant difference with intergroup(p>.05). But there was a statistically significant difference with each groups (p<.05). 2. WBC has no statistically significant difference with intergroup (p>.05). But there was a statistically significant difference in control group (p<.05), without experimental group (p>.05). 3. LDL-C has no statistically significant difference with intergroup (p>.05). But there was a statistically significant difference in control group (p<.05), without experimental group (p>.05). 4. HDL-C has no statistically significant difference with intergroup (p<.05). But there was a statistically significant difference with each groups (p>.05). 5. Troponin Ⅰ has no statistically significant difference with intergroup (p>.05). Also there was no statistically significant difference with each groups (p>.05). Conclusion: These findings suggest that different quantitative exercises has no effect on FMS, LDL-C, HDL-C, WBC, Troponin Ⅰ with ischemic stroke patients. But the treatment period that there's less correlation between the recovery of motor function and the different quantitative exercise, also less correlation between the change of important blood factors and the different quantitative exercises with ischemic stroke patients.

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Glucose recovery from different corn stover fractions using dilute acid and alkaline pretreatment techniques

  • Aboagye, D.;Banadda, N.;Kambugu, R.;Seay, J.;Kiggundu, N.;Zziwa, A.;Kabenge, I.
    • Journal of Ecology and Environment
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    • v.41 no.7
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    • pp.191-201
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    • 2017
  • Background: Limited availability of corn stover due to the competing uses (organic manure, animal feed, bio-materials, and bioenergy) presents a major concern for its future in the bio-economy. Furthermore, biomass research has exhibited different results due to the differences in the supply of enzymes and dissimilar analytical methods. The effect of the two leading pretreatment techniques (dilute acid and alkaline) on glucose yield from three corn stover fractions (cob, stalk, and leaf) sourced from a single harvest in Uganda were studied at temperatures 100, 120, 140, and $160^{\circ}C$ over reaction times of 5, 10, 30, and 60 min. Results: From this study, the highest glucose concentrations obtained from the dilute acid (DA) pretreated cobs, stalks, and leaves were 18.4 g/L (66.8% glucose yield), 16.2 g/L (64.1% glucose yield), and 11.0 g/L (49.5% glucose yield), respectively. The optimal pretreatment settings needed to obtain these yields from the DA pretreated samples were at a temperature of $160^{\circ}C$ over an incubation time of 30 min. The highest glucose concentrations obtained from the alkaline (AL) pretreated cobs, stalks, and leaves were 24.7 g/L (81.73% glucose yield), 21.3 g/L (81.23% glucose yield), and 15.0 g/L (51.92% glucose yield), respectively. To be able to achieve these yields, the optimal pretreatment settings for the cobs and stalks were $140^{\circ}C$ and for a retention time of 30 min, while the leaves require optimal conditions of $140^{\circ}C$ and for a retention time of 60 min. Conclusions: The study recommends that the leaves could be left on the field during harvesting since the recovery of glucose from the pretreated cobs and stalks is higher.

Acupuncture Treatment about Medial Meniscus Posterior Horn Rupture : A Case Report

  • Lee, Hey-Jin;Lee, Nam-Heon;Son, Chang-Gue;Cho, Jung-Hyo
    • Journal of Haehwa Medicine
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    • v.29 no.2
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    • pp.30-37
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    • 2020
  • Objectives : In this case, the knee joint inconvenience with deteriorating pain has been relieved by acupuncture treatment for a patient was 51-year-old male with a left medial meniscal posterior horn rupture in 2012. Methods : Twenty-four times of acupuncture treatments were performed for Twelve weeks from July 2016 to improve the disease. SP8(Jigi; 地機), BL63(Geummun; 金門), KI3(Taegye; 太谿), LI4(Hapgok; 合谷) were chosen for treatment by principles of Traditional Korean Medicine. Results : Numeric Rating Scales, which means subjective pain, decreased from 6 points to 3 points out of 10 points in total. Pressure Pain Threshold, which means sensitivity to pressure applied to the affected area, increased from 21N to 47N on the lateral-inferior side and from 19N to 50N on the lateral side. K-WOMAC, which indicates discomfort of knee-related activity, was 56 points out of 96 points in total before treatment and 4 points after treatment, 13 points after two years, and 15 points after four years. However, MRI tests conducted before and after treatment did not identify any significant changes. As a result, we confirmed that a total of 24 acupuncture treatments had resulted in the relief objective and subjective pain and functional recovery, especially in the case of the knee function, maintained until after four years later. There was no significant substrate recovery in meniscal rupture.

The Fabrication of Packaged 4H-SiC 2kV power PiN diode and Its Electrical Characterization (탄화규소 (4H-SiC) 기반 패키지 된 2kV PiN 파워 다이오드 제작과 전기적 특성 분석)

  • Song, Jae-Yeol;Kang, In-Ho;Bahng, Wook;Joo, Sung-Jae;Kim, Sang-Cheol;Kim, Nam-Kyun;Lee, Yong-Jae
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.67-68
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    • 2008
  • In this study we have developed a packaged silicon carbide power diode with blocking voltage of 2kV. PiN diodes with 7 field limiting rings (FLRs) as an edge termination were fabricated on a 4H-SiC wafer with $30{\mu}m$-thick n-epilayer with donor concentration of $1.6\times10^{15}cm^{-3}$. From packaged PiN diode testing, we obtained reverse blocking voltage of 2kV, forward voltage drop of 4.35V at 100A/$cm^2$, on-resistance of $6.6m{\Omega}cm^2$, and about 8 nanosec reverse recovery time. These properties give a potential for the power system application.

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Studies on the Grassland Management in Late-Autumn and Early-Spring V. Effect of fertilizer application time in early spring on growth, yield and nutritive value of grasses for hay (월동전후 초지관리에 관한 연구 VI. 봄철 건초이용초지에서 이른 봄 추비시용시기가 목초의 생육과 수량 및 사료가치에 미치는 영향)

  • Kim, Jae-Kyu;Seo, Sung
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.9 no.3
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    • pp.148-152
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    • 1989
  • This field experiment was carried out to determine the effects of fertilizer application time in early spring on growth, dry matter (DM) yield, crude protein (CP) content, crude protein yield (CPY), N recovery, acid detergent fibej (ADF) content and DM digestibility (DMD) of grasses for hay. Application times of fertilizer were March 10, 20, 30, April 9. 19, and control (non-fertilized) plot was involved. The fust harvesting data for hay was May 9 (early heading stage) and the regrowth yields were investigated for soiling, 1989. In all fertilized plots, the growth, DM yield, CP, CPY and N recovery of grasses were significantly increased compared with control, and the best grass growth, DM yield, CP, CPY, N recovery and DMD were observed on March 20 and 30 among all fertilized plots. On March 20 and 30 in this experiment, the accumulated temperature was 200 and 280^{\circ}C.$, and the subsoil temperature at 10 cm depth was 8 and 10^{\circ}C.$. Considering the average meteorological condition in Suwon area, the optimum application time of early spring for hay may be recommended from April 10 to 15. i\ulcornerfW3U% (L. westock Experiment Station, RDA. Suwon 440 - 350. Korea)

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A Continuous Process for Phosphorus Recovery from Swine Slurry with Forming Struvite (양돈액비에서 Struvite 형성으로 연속적 인의 회수기술)

  • Oh I.H.;Lee J.H.;Choi B.H.;Burns R.T.
    • Journal of Animal Environmental Science
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    • v.12 no.2
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    • pp.95-100
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    • 2006
  • This study was carried out to develop a continuous process for recovering phosphorus in swine slurry. Magnesium chloride ($MgCl_2$) was used in the test as a magnesium source and the pH was regulated by adding NaOH and aerating. The results showed that the recovery rate of soluble phosphorus (SP) has increased with the molar ratios increased. In case of pH regulated with NaOH, the recovery rates of SP with molar ratio of 1:1.5 were over 95% from both farms. The removal of ammonia-nitrogen was at levels of $4{\sim}9%$. With aeration treatment, the SP recovery rate was 66% and the removal rate of ammonia-nitrogen was 15%. The treatment of NaOH to increase pH showed better SP recovery efficiency than the aeation treatment. However, in case of ammonia-nitrogen removal, the treatment of aeration showed better results than the NaOH treatment.

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Comparison Solid Phase Microextraction with Purge & Trap on the GC/MS Analysis of Volatile Organic Compounds in Biota Samples (Solid Phase Microextraction 및 Purge & Trap을 이용한 생물시료 중 휘발성 유기화합물의 GC/MS 분석비교)

  • Ahn, Yun-Gyong;Seo, Jong-Bok;Hong, Jongki
    • Analytical Science and Technology
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    • v.14 no.5
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    • pp.392-399
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    • 2001
  • The analysis of n-butylbenzene and 1,2-dibromo-3-chloropropane (DBCP) as volatile organic compounds in biota samples was performed by gas chromatography/mass spectrometry-selected ion monitoring mode. The target compounds, n-butylbenzene and DBCP, in biota samples were extracted by headspace solid phase microextraction (SPME) with $100{\mu}m$ polydimethyl siloxane (PDMS) fiber and purge & trap method. The extraction recoveries of these compounds obtained by SPME was 85.8% for n-butylbenzene and 92.4% for DBCP, respectively. Each value of method detection limit were $0.15{\mu}g/kg$ and $0.05{\mu}g/kg$, respectively. While in the case of purge & trap method, the extraction recovery was 115.2% for n-butylbenzene, 80.9% for DBCP and method detection limit were $0.04{\mu}g/kg$ and $0.70{\mu}g/kg$, respectively. The extraction yields and detection limits of these compounds obtained by purge & trap were equivalent to those by SPME.

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The Evaluation of Mechanical Properties for Alumina Ceramics (알루미나 세라믹스의 기계적 특성 평가)

  • 임헌진;조덕호;김무경;한상미;이와사미키오
    • Journal of the Korean Ceramic Society
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    • v.33 no.3
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    • pp.339-347
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    • 1996
  • Mechanical properties(flexural strength hardness fracture toughness) of alumina ceramics were evaluated. Alumina products of four companies were selected and three of those were made in Korea and one of those was made in Japan. The large differences according to manufacturing companies had resulted from flexural strength and weibull modulus which had a wide ranges of 300 to 400 MPa and 5 to 15 respectively. Critical indenstation load which could be neglected the effect of elastic recovery was about 9.8N and Vickers' hardness were about 15 GPa. Fracture toughnesses were evaluated by IF and ISB method. It was more preferable to the average at one indentation load that fracture toughness were obtained from the slope of the relationship between indentation load and crack length in IF method and between indentation load and fracture load in ISB method and fracture toughness was about 4 MPa·m1/2.

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