• Title/Summary/Keyword: $^{123}In$

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On the Optical Activity of Critical Fluid

  • Lee, Dong-Jae;Kim, Shoon-Kyung
    • Bulletin of the Korean Chemical Society
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    • v.6 no.3
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    • pp.123-124
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    • 1985
  • The optical activity of a fluid in the extreme critical region, where the Ornstein-Zernike theory does not hold, is explicitly obtained. We suggest new experimental methods to measure the critical exponent for correlation function by using the results of circular dichroism and optical rotation given in this paper.

A Study of 123 prescriptions in high-chepter from Bang-Yak-Hap-Pyun (Mainly Basic-prescriptions) (방약합편(方藥合編) 상통(上統) 처방(處方)에 대한 방제학적(方劑學的) 고찰(考察))

  • Lee, Sang-Hyun
    • Herbal Formula Science
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    • v.17 no.1
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    • pp.1-16
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    • 2009
  • This report describes the studies as follows through the research of Basic-prescriptions about 123 prescriptions in high-chepter(上統) from Bang-Yak-Hap-Pyun(方藥合編). There are 24 Basic-prescriptions including Sagunja-tang(四君子湯), Samul-tang(四物湯), Sogeonjung-tang(小建中湯), lijung-tang(理中湯), Dangguibohyul-tang(當歸補血湯), Yijin-tang(二陳湯), Gauwon-chun(擧元煎), Jeongweon-eum(貞元飮), and Yukmichiwhang-won(六味地黃元), etc. about 123 prescriptions in high-chepter(上統) from Bang-Yak-Hap-Pyun(方藥合編). There were many cases compounding the Basic-prescriptions each other. So I investigated those cases. The results were the other typed (blended) Basic-prescriptions including Palmul-tang(八物湯), Sipjeondaebo-tang(十全大補湯), Yukgunja-tang(六君子湯), Bojungyikkee-tang(補中益氣湯), SsangHwa-tang(雙和湯), and Gwibitang(歸脾湯). And I investigated about pathologies in connection with these Basic-prescriptions. Oriental Medical Pathology applied with these Basic-prescriptions were Giheo(氣虛), hyulheo(血虛), Gihyulguheo(氣血俱虛), Biheohan(脾虛寒), Giheo-dameum(氣虛痰飮), Giheohaham(氣虛下陷), Sineumheo(腎陰虛), etc. These results indicated that 123 prescriptions in high-chepter from Bang-Yak-Hap-Pyun are composed of Bojei(補劑) to treatment against many kinds of Infirmity and promote physiological function.

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Forced Convective Boiling of Refrigerant-Oil Mixtures in a Bundle of Enhanced Tubes Having Pores and Connecting Gaps

  • Park, Ji-Hoon;Kim, Nae-Hyun;Kim, Do-Young;Byun, Ho-Won;Choi, Yong-Min;Kim, Soo-Hwan
    • International Journal of Air-Conditioning and Refrigeration
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    • v.17 no.3
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    • pp.81-87
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    • 2009
  • The effect of oil on convective boiling of R-123 in an enhanced tube bundle is experimentally investigated at $26.7^{\circ}C$ saturation temperature. The enhanced tube had pores (0.23 mm diameter) and connecting gaps (0.07 mm width), which had been optimized using pure R-123. The effects of oil concentration (0 to 5%), heat flux (10 to $40\;kW/m^2$), mass velocity (8 to $26\;kg/m2^s$) and vapor quality are investigated. The oil significantly reduces the bundle boiling heat transfer coefficient. With 1% oil, the reduction is approximately 35%. Further addition of oil further reduces the heat transfer coefficient. The data are also compared with the pool boiling counterpart. The reduction in the heat transfer coefficient is smaller in a bundle (convective boiling) than in a pool (single-tube pool boiling), with larger difference at a smaller heat flux. Similar to pure R-123 case, the effects of mass velocity and vapor quality are negligible for the convective boiling of R-123/oil mixture.

Screening of Differentially Expressed Genes between PC12 Cells and A123.7 Cells (PC12 세포와 A123.7 세포에서 차별적으로 발현되는 유전자의 검색)

  • Baik, Seung-Youn;Yang, Byung-Hwan;Chai, Young-Gyu
    • Korean Journal of Biological Psychiatry
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    • v.6 no.1
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    • pp.67-73
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    • 1999
  • The cAMP-dependent protein kinase(PKA) is an intracellular enzyme with serine-threonine kinase activity that plays a key role in cell growth, differentiation, and apoptosis in eukaryotes. In order to understand the PKA signal transduction pathway regulating cell life cycle and identify its role, we focused on the characterization of up-/down-regulated genes by PKA using the differential display polymerase chain reaction. Seven differentially expressed sequence tags(DEST) have been obtained. Among these DESTs, 2 DESTs were homologous to the sequence of genes from BLAST search result. KC1-5 DEST that was up-regulated in A123.7 cells was highly corresponded to mouse apoptosis-related gene(MA-3) or mouse mRNA for topoisomerase inhibitor suppressed(TIS). MA-3 was induced in various types of apoptosis, specially in NGF-deprived apoptotic PC12 cells. TIS was down-regulated in the RVC lymphoma cells incubated with topoisomerase inhibitor that induces DNA strand breakages. PG1-1 DEST that was highly expressed in PC12 cells was corresponded to transposon Tn10 3'-end. Tnansposon Tn10 was up-regulated in differentiated myeloblastic ML-1 cells by 12-O-tetradecanoylphorbol-13-acetate. This study illuminates that MA-3/TIS was down-regulated by PKA activity, and transposon Tn10 was up-regulated by it.

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Molecular Imaging of Arthritis in the Angiogenic Vasculature Using A 123I-Vascular Endothelial Growth Factor Receptor Antibody

  • Kim, Sung-Min;Choi, Na-Eun;Song, Young-Kyu;Cho, Gyung-Goo;Bang, Jeong-Kyu;Kim, Sang-Mi;Lee, Sang-Hoon;Ryu, Eun-Kyoung
    • Bulletin of the Korean Chemical Society
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    • v.33 no.6
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    • pp.1890-1894
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    • 2012
  • Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been implicated in the pathogenesis of rheumatoid arthritis, which is angiogenesis dependent. Antibody-based molecular imaging improves targeting, and antibody radiolabeling is useful for monitoring biological events $in$ $vivo$ $via$ PET or SPECT. We investigated the potential of molecular imaging to diagnose arthritis with VEGFR-2 $in$ $vivo$. The $^{123}I$-VEGFR-2 antibody was prepared by the iodogen tube method. The radioligand was injected into arthritic mice, and micro SPECT/CT was performed. The arthritic mice were examined by 4.7-T MRI and immunohistochemistry. The $^{123}I$-VEGFR-2 antibody showed high uptake in the arthritic region at 1 h postinjection on SPECT/CT but no uptake in the control animals after radioligand injection. In MR images, the arthritic tissue of the mice was correlated with regions labeled by the $^{123}I$-VEGFR-2 antibody. Immunohistochemical localization showed markedly increased expression of VEGFR-2 in the endothelial cells, fibroblasts, and macrophages of the arthritic mice.

A Proposal of Educational 3D Modelling Software Development Type Via User Experience Analysis of Open Source 3D Modelling Software (무료공개 3D모델링 소프트웨어 사용자 경험 분석을 통한 교육용 3D모델링 소프트웨어 개발유형 제안)

  • Lee, Guk-Hee;Cho, Jaekyung
    • Science of Emotion and Sensibility
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    • v.20 no.2
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    • pp.87-102
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    • 2017
  • With increasing interest in 3D printing, the interest in the 3D modelling training that should precede the 3D printing is increasing. However, the existing 3D modelling software is developed mostly by foreign brands. Thus, the interfaces are all in English. 3D modelling software training for Korean novices who are not familiar with these terms has constraints. This study aims to explore what to consider when developing a Korean model for 3D modelling educational software for 3D printing in the face of such reality. For this goal, after having novices with no experience in 3D modeling to perform a house building task using either 12D Design or Tinker CAD, we conducted a survey. It was found in the result that more users favored Tinker CAD over 123D Design, and the errors involved while working with the Tinker CAD were less than those with the 123D Design, and the ratio of people who completed the task with the Tinker CAD was higher than that with the 123D Design. In general discussion, an introductory level educational 3D modeling software development is proposed which utilize characteristics of Tinker CAD (easy modelling is possible by three-dimensional figures) and web-based method. Also, a beginner/intermediate level educational 3D modeling software development is proposed which utilize characteristics of 123D Design (with finer measurement manipulations and figure alignment) and Windows-based method.