• Title/Summary/Keyword: $^{11}C$ Beam

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Pridiction of Case Depth in Laser Beam Hardening (레이저 표면경화에서 경화깊이 예측)

  • Kim, Jae-Do;Cho, Chong-du;Seo, Jung-Won;Cho, Yong-Moo
    • Journal of the Korean Society for Precision Engineering
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    • v.12 no.6
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    • pp.87-95
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    • 1995
  • In order to predict the case depth and case width in laser transformation hardening, a finite element method was used to analyze the temperature distribution on the material. Laser hardening of the specimens of SM45C and STE11steels was experimented by using the continuous wave CO$_{2}$ laser with the various travel speeds and the defocused Gaussian beam mode. Phosphate coating was adopted on the surface of SM45C to increase the absorption of 10.6 .mu. m laser energy. Experimental data show good agreement with the theoretical predictions. The maximum possible case depth can be predicted for the given laser hardening conditions, such as laser power, and travel speed.

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Improvement of Radiosynthesis Yield of [11C]acetate ([11C]아세트산의 방사화학적 수율 증가를 위한 연구)

  • Park, Jun Young;Son, Jeongmin
    • The Korean Journal of Nuclear Medicine Technology
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    • v.22 no.2
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    • pp.74-78
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    • 2018
  • Purpose $[^{11}C]$acetate has been proved useful in detecting the myocardial oxygen metabolism and various malignancies including prostate cancer, hepatocellular carcinoma, renal cell carcinoma and brain tumors. The purpose of study was to improve the radiosynthesis yield of $[^{11}C]$acetate on a automated radiosynthesis module. Materials and Methods $[^{11}C]$acetate was prepared by carboxylation of grignard reagent, methylmagnesium chloride, with $[^{11}C]$$CO_2$ gas, followed by hydrolysis with 1 mM acetic acid and purification using solid phase extraction cartridges. The effect of the reaction temperature ($0^{\circ}C$, $10^{\circ}C$, $-55^{\circ}C$) and cyclotron beam time (10 min, 15 min, 20 min, 25 min) on the radiosynthesis yield were investigated in the $[^{11}C]$acetate labeling reaction. Results The maximum radiosynthesis yield was obtained at $-10^{\circ}C$ of reaction temperature. The radioactivities of $[^{11}C]$acetate acquired at $-10^{\circ}C$ reaction temperature was 2.4 times higher than those of $[^{11}C]$acetate acquired at $-55^{\circ}C$. Radiosynthesis yield of $[^{11}C]$acetate increased with increasing cyclotron beam time. Conclusion This study shows that radiosynthesis yield of $[^{11}C]$acetate highly dependent on reaction temperature. The best radiosynthesis yield was obtained in reaction of grignard reagent with $[^{11}C]$$CO_2$ at $-10^{\circ}C$. This radiolabeling conditions will be ideal for routine clinical application.

Development and optimization of C-11 gas target system in KOTRON-13 cyclotron (KOTRON-13 사이클로트론의 고효율C-11 가스 표적장치)

  • Lee, Hong-Jin;Lee, Won-Kyeong;Park, Jun-Hyung;Moon, Byung-Seok;Lee, In-Won;Chae, Sung-Ki;Lee, Byung-Chul;Kim, Sang-Eun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.1
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    • pp.86-89
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    • 2011
  • Purpose: The KOTRON-13 cyclotron was developed in South Korea and was introduced to regional cyclotron centers to produce short-lifetime medical radioisotopes. However, this cyclotron has limited capacity to produce carbon-11 isotope so far. We herein study how to develop and optimize an effective carbon-11 target system in the KOTRON-13 cyclotron by changing cooling system, combing with fluorine-18 target and evaluating beam currents. Materials and Method: To develop the optimal carbon-11 target and an effective cooling system, we designed the carbon-11 target system by Stopping and Range of Ions in Matter (SRIM) simulation program and considered the cavity pressure during irradiation at target grid. In this investigation, we evaluated the yield of carbon-11 production at different beam currents and the stability of the operation of the KOTRON-13 cyclotron. Results: The production of carbon-11 was enhanced from about 1.700 mCi ($50{\mu}A$) to 2,000 mCi ($60{\mu}A$) on the carbon-11 target which developed by seoul national university bundang hospital (SNUBH) and Samyoung Unitech. Additionally, the cooling condition was showed stable to produce carbon-11 under high beam current. Conclude: The carbon-11 target system of the KOTRON-13 cyclotron was successfully developed and improved carbon-11 production. Consequently, the operation of carbon-11 target system was highly effective and stable compare with other commercial cyclotrons. Our results are believed that this optimal carbon-11 target system will be helpful for the routine carbon-11 production in the KOTRON-13 cyclotron.

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Performance Analysis of Beam Steering Algorithm According to the Signal Separation (신호 이격도에 따른 빔 제어 알고리즘 성능 분석)

  • Yun, Seonhui;Oh, Jongchan;Kim, Jun O;Nam, Juhun;Choi, Sangwook;Ahn, Jaemin
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.11
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    • pp.1023-1030
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    • 2014
  • Beam steering algorithms using array antenna are mainly used in such a manner as anti-jamming method. However, the performance is changed according to the position of signals despite the same number of signals and the same received power. In this paper, we analyzed the effect of the position relationship of the signals on the performance of the beam steering algorithms. Therefore, we defined 'signal separation' as the minimum angle of the interference signals and the desired signal, and analysed the relationship between the C/N0 performance of beam steering algorithms as LCMV/PM and the signal separation. For simulation, we set many GPS signals and jamming signals compared to the degrees of freedom. And changed the position and the height of the receiver in order to obtain various signal separation angles. In addition, we examined the effects of signal separation and JSR on the anti-jamming performance by applying the loss factors of the received power. Through the research, there is a tendency that the performance of beam steering algorithms is increased with the increase of the signal separation, and signal separation is more severely affecting on the anti-jamming performance compared to the number of signals and JSR.

Consecutive automated production of carbon-11 labeled radiopharmaceuticals by sharing 11C-methylation reagent from one 11C-synthetic module

  • Park, Hyun Sik;Lee, Hong Jin;An, Hyun Ho;Moon, Byung Seok;Lee, Byung Chul;Kim, Sang Eun
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.2 no.2
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    • pp.123-131
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    • 2016
  • Increasing clinical demand for carbon-11 labeled radiopharmaceuticals has triggered technological advances in fields of radiochemistry and automated modules. Even though carbon-11 has a short half-life ($t_{1/2}=20.4min$), the consecutive second production of carbon-11 labeled radiopharmaceutical in one $^{11}C$-synthetic module should be delayed at least over 4 h to avoid the high radiation exposure. We herein aimed to produce two different carbon-11 labeled radiopharmaceuticals ([$^{11}C$]PIB and [$^{11}C$]methionine) by sharing of [$^{11}C$]methylation source in one $^{11}C$-synthetic module. The synthesis of $^{11}C$-labeling reagents ($[^{11}C]CH_3I$ or $[^{11}C]CH_3OTf$) is fully automated using the commercial TRACERlab $FX_{C-pro}$ module and is readily adaptable to $^{11}C$-labeling reactor for [$^{11}C$]PIB as well as another $^{11}C$-labeling apparatus for [$^{11}C$]methionine via the three-way valve. After completing the [$^{11}C$]PIB production, the re-synthesized $[^{11}C]CH_3I$ was passed through the three-way valve connected the polyetheretherketone (PEEK) line and loaded into the C18 Sep-Pak cartridge including the methionine precursor. The labeled product [^${11}C$]methionine was purified by a simple cartridge separation and reformulated into saline. The radiochemical yield of [$^{11}C$]PIB and [$^{11}C$]methionine were $5.3{\pm}0.6%$ and $18.7{\pm}0.8%$ (n.d.c.), respectively, with over 97% of radiochemical purity. The specific activity of [$^{11}C$]PIB was over $110GBq/{\mu}mol$. Total production time of two radiopharmaceuticals needs about 2 h from $1^{st}$ beam irradiation including quality control tests. Final [$^{11}C$]PIB and [$^{11}C$]methionine were satisfied all quality control test standards.

Seismic Behavior of Slender Coupling Beams Constructed with High-Performance Fiber Reinforced Cementitious Composite (고성능 섬유 보강 시멘트 복합체(HPFRCC)를 적용한 세장한 연결보의 내진거동 평가)

  • Han, Sang Whan;Kwon, Hyun Wook;Shin, Myung Su;Lee, Ki Hak;Cho, Young Wook
    • Journal of the Earthquake Engineering Society of Korea
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    • v.17 no.6
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    • pp.271-278
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    • 2013
  • The hysteretic behavior of diagonal reinforced coupling beams is excellent during earthquakes. However, construction of the diagonal reinforced coupling beams is difficult due to complex reinforcement details required by current code procedures (ACI 318-11). Due to the detail requirement, reinforcement congestion and interference among transverse reinforcement always occur during construction field. When the aspect ratio of the beam is large, the interference of reinforcement becomes more serious. The objective of this paper is to simplify the reinforcement details of slender coupling beams by reducing transverse reinforcement around the beam perimeter. For this purpose, high- performance fiber reinforced cementitious composites are used for making coupling beams. Experiments were conducted using three specimens having aspect ratio 3.5. Test results showed that HPFRCC coupling beams with half the transverse reinforcement required by ACI 318-11 provided identical seismic capacities to the corresponding coupling beams having requirement satisfying the requirement specified in ACI 318-11.

Balanced Ratio of Concrete Beams Internally Prestressed with Unbonded CFRP Tendons

  • Lee, C.;Shin, S.;Lee, H.
    • International Journal of Concrete Structures and Materials
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    • v.11 no.1
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    • pp.1-16
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    • 2017
  • The compression or tension-controlled failure mode of concrete beams prestressed with unbonded FRP tendons is governed by the relative amount of prestressing tendon to the balanced one. Explicit assessment to determine the balanced reinforcement ratio of a beam with unbonded tendons (${\rho}^U_{pfb}$) is difficult because it requires a priori knowledge of the deformed beam geometry in order to evaluate the unbonded tendon strain. In this study, a theoretical evaluation of ${\rho}^U_{pfb}$ is presented based on a concept of three equivalent rectangular curvature blocks for simply supported concrete beams internally prestressed with unbonded carbon-fiber-reinforced polymer (CFRP) tendons. The equivalent curvature blocks were iteratively refined to closely simulate beam rotations at the supports, mid-span beam deflection, and member-dependent strain of the unbonded tendon at the ultimate state. The model was verified by comparing its predictions with the test results. Parametric studies were performed to examine the effects of various parameters on ${\rho}^U_{pfb}$.

Formulation Method for Solid-to-Beam Transition Finite Elements

  • Im, Jang-Gwon;Song, Dae-Han;Song, Byeong-Ho
    • Journal of Mechanical Science and Technology
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    • v.15 no.11
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    • pp.1499-1506
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    • 2001
  • Various transition elements are used in general for the effective finite element analysis of complicated mechanical structures. In this paper, a solid-to-beam transition finite element, which can b e used for connecting a C1-continuity beam element to a continuum solid element, is proposed. The shape functions of the transition finite element are derived to meet the compatibility condition, and a transition element equation is formulated by the conventional finite element procedure. In order to show the effectiveness and convergence characteristics of the proposed transition element, numerical tests are performed for various examples. As a result of this study, following conclusions are obtained. (1) The proposed transition element, which meets the compatibility of the primary variables, exhibits excellent accuracy. (2) In case of using the proposed transition element, the number of nodes in the finite element model may be considerably reduced and the model construction becomes more convenient. (3) This formulation method can be applied to the usage of higher order elements.

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Development of Optimum Design Program for Reinforced Concrete Continuous Beam Using Graphic User Interface System (GUI를 이용한 철근콘크리트 연속보의 최적설계프로그램 개발)

  • 조홍동;이상근;박중열;한상훈
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.13 no.1
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    • pp.1-11
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    • 2000
  • In this paper, optimum design problem of R.C. continuous beam is considered and GUI system is developed for using at the practical design. Objective function lot formulation of optimum design problem is made up of the costs of concrete, reinforcing steel and formwork. Design variables are width, effective depth of the beam and steel ratio and design constraints are considered on the strength, serviceability, durability and geometrical conditions. The optimum design problem is solved by using sequential linear programming(SLP), sequential convex programming(SCP) and compared their effectiveness. Also this paper shows the application at practical design work according to the development of GUI system using visual basic.

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AN EXPERIMENTAL STUDY ON THE TEMPERATURE CHANGE OF THE PULP CHAMBER INDECED BY THE CO2 LASER IRRADIATION (CO2레이저 조사에 따른 치수강내 온도변화에 관한 실험적 연구)

  • Lee, Jong-Man;Park, Dong-Soo;Lee, Chang-Young;Lee, Chung-Suck
    • Restorative Dentistry and Endodontics
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    • v.10 no.1
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    • pp.43-53
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    • 1984
  • The purpose of this study was to suggest the use of laser energy in the the field of operative dentistry without considerable pulpal damage and significant effects on the dental hard tissue, additionally to find out the methods which could control the temperature rise. The laser beam (CW $CO_2$ laser, output: 6W, beam diameter: 1.5mm) was focused on the center of the occlusal surface of extracted lower molars. A Ge lens (focal length 200mm) was used to focus the primary laser beam. In order to vary the total amount of the same irradiated energy, experimental subjects were devided into three groups: continuously irradiated group, intermittently irradiated group, and water-cooled group after continuous laser irradiation. Temperature changes in the pulp chamber after laser irradiation were measured and recorded by the digital thermometer and recorder. The following results were obtained: 1. Temperatures in the pulp chamber were raised up in the order of the continuously irradiated group, intermittently irradiated group, water-cooled group after continuous laser irradiation. 2. In the continuously irradiated group, the temperature was raised up $1.7^{\circ}C$, $3.8^{\circ}C$, $7.3^{\circ}C$, $17.2^{\circ}C$ after 2, 4, 8, 16 seconds of the irradiation of laser. In the intermittently irradiated group, the changes were $1.2^{\circ}C$, $3.4^{\circ}C$, $6.3^{\circ}C$, $11.1^{\circ}C$, respectively. In the water-cooled group after continuous laser irradiation, the changes were $0.0^{\circ}C$, $0.8^{\circ}C$, $1.6^{\circ}C$, $6.9^{\circ}C$, respectively. 3. The starting time of temperature rise in the pulp chamber had no connection with laser irradiation time.

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