• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.515-519
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• 2005

We hypothesized that the IL10 gene is important candidate in the development of Bell's palsy and specific genotypic and allelic variations should be associated with Bell's palsy in the Korean population. In this study, we assessed the SNP (single-nucleotide polymorphism) of IL10 in patients with Bell's palsy. 62 patients with Bell's palsy were selected from the subjects who visited for the Bell's palsy service of the department of acupuncture & moxibustion, college of Oriental Medicine, Daegu Haany University from May 2002 to May 2003. Pyrosequencing was performed for genetic analyses. There was no statistically significant genotypic distribution difference between control and Bell's palsy group And there was not statistically significant allelic frequency difference between control and Bell's palsy group. In this study the IL10 genotypemight not be the risk factor of Bell's palsy patients in Korean. studies will be necessary for the exact genetic markers. Establishment of more systemic approach and high quality of prospective cohorts will be necessary for the good prediction of genetic markers.

• The Pure and Applied Mathematics
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• v.28 no.3
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• pp.217-234
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• 2021

In this paper, first we introduce the new class of HV-BE-algebra as a generalization of a (hyper) BE-algebra and prove some basic results and present several examples. Then, we construct the HV-BE-algebra associated to a BE-algebra (namely BL-BE-algebra) based on "Begins lemma" and investigate it.

• Journal of Sensor Science and Technology
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• v.21 no.1
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• pp.34-38
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• 2012

We have developed a cost effective test socket for ball grid array(BGA) integrated circuit(IC) packages using BeCu metal sheet as a test probe. The BeCu furnishes the best combination of electrical conductivity and corrosion resistance. The probe of the test socket was designed with a BeCu cantilever. The cantilever was designed with a length of 450 ${\mu}m$, a width of 200 ${\mu}m$, a thickness of 10 ${\mu}m$, and a pitch of 650 ${\mu}m$ for $11{\times}11$ BGA. The fabrication of the test socket used techniques such as through-silicon-via filling, bonding silicon wafer and BeCu metal sheet with dry film resist(DFR). The test socket is applicable for BGA IC chip.

• Journal of the Optical Society of Korea
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• v.8 no.2
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• pp.55-58
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• 2004

Several internal wavelength locker schemes for 10 Gbps electro-absorption modulated laser EML) module were reviewed. 10 Gbps EML modules with simple and robust internal wavelength ockers for metro dense WDM application were successfully demonstrated. The wavelength aging ver 2000 hours was done at elevated temperature of 7$0^{\circ}C$. The average wavelength drift of 10 modules was measured to be about $\pm$ 5 pm. These modules can be successfully applied to the 0 Gbps DWDM systems with 50 ㎓ channel spacing.

• Korean Journal of Materials Research
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• v.25 no.9
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• pp.487-491
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• 2015

In photovoltaic power generation where minority carrier generation via light absorption is competing against minority carrier recombination, the substrate thickness and material quality are interdependent, and appropriate combination of the two variables is important in obtaining the maximum output power generation. Medici, a two-dimensional semiconductor device simulation tool, is used to investigate the interdependency in relation to the maximum power output in front-lit Si solar cells. Qualitatively, the results indicate that a high quality substrate must be thick and that a low quality substrate must be thin in order to achieve the maximum power generation in the respective materials. The dividing point is $70{\mu}m/5{\times}10^{-6}sec$. That is, for materials with a minority carrier recombination lifetime longer than $5{\times}10^{-6}sec$, the substrate must be thicker than $70{\mu}m$, while for materials with a lifetime shorter than $5{\times}10^{-6}sec$, the substrate must be thinner than $70{\mu}m$. In substrate fabrication, the thinner the wafer, the lower the cost of material, but the higher the cost of wafer fabrication. Thus, the optimum thickness/lifetime combinations are defined in this study along with the substrate cost considerations as part of the factors to be considered in material selection.

• Journal of radiological science and technology
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• v.46 no.6
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• pp.493-499
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• 2023

This study developed education contents of measuring spatial dose with virtual reality simulation and applied to students majoring radiological science. The virtual reality(VR) contents with measuring spatial dose rate in the radiation controlled area was developed based on the simulation from pilot study. In this simulation, the tube voltage and tube current can be set from 60 to 120 kVp in 10 kVp steps and 10 to 40 mAs in 10 mAs increments, and the distance from source can be set from 30 to 400 cm continuously. Iron and lead shields can be placed between the source and the detector, and shielding thickness can be set by 1 mm increments ranging from 1 to 20 mm. We surveyed to students for evaluating improvement of understanding spatial dose rate between before and after education by VR simulation. The survey was conducted with 5 questions(X-ray exposure factors, effects by distance from the source, effects from using shield, depending on material and thickness of shield, concept and measuring of spatial dose rate) and all answers showed significant improvement. Therefore, this VR simulation content will be well used in education for spatial dose rate and radiation safety environments.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2006.11a
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• pp.127-130
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• 2006

Coenzyme Q10(CoQ10) is a biological quinine compound that is widely found in living organisms including yeast, plants, and animals. CoQ10 has two major physiological activities:(a)mitochondrial electron-transport activity and (b )antioxidant activity. Various clinical applications are also available: Parkinson's disease, Heart disease, diabetes. Because of its various application filed, the market size of CoQ10 is continuously expanding all over the world. A Japanese company, Nisshin Pharma Inc. is the first industrial producer of CoQ10(1974). CoQ10 can be produced by fermentation and chemical synthesis. In several companies, these two methods are used for the production of CoQ10:chemical synthesis - Yungjin, Daewoong, Nishin Parma; fermentation - Kaneka, Kyowa, Yungjin, etc. Researchs in microbial production of CoQ10 have several steps: screening of producing microorganisms, strain development, fermentation process, purification process, scale-up process, plant production. Several strategies are available for the strain development : Random mutation and screening, directed metabolic engineering. For the optimization of fermentation process, various conditions (nutrient, aeration, temperature, culture type, etc.) are considered. Purification is one of the most important step because the quality of final products entirely depends on its purity. The production cost will be reduced and the quality of the CoQ10 will be impoved by continuous researches in strain development, fermentation process, purification process.

• 한국약용작물학회:학술대회논문집
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• 2006.11a
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• pp.127-130
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• 2006

Coenzyme Q10(CoQ10) is a biological quinine compound that is widely found in living organisms including yeast, plants, and animals. CoQ10 has two major physiological activities:(a)mitochondrial electron-transport activity and (b)antioxidant activity. Various clinical applications are also available : Parkinson's disease, Heart disease, diabetes. Because of its various application filed, the market size of CoQ 10 is continuously expanding all over the world. A Japanese company, Nisshin Pharma Inc. is the first industrial producer of CoQ10(1974). CoQ10 can be produced by fermentation and chemical synthesis. In several companies, these two methods are used for the production of CoQ10:chemical synthesis - Yungjin, Daewoong, Nishin Parma; fermentation - Kaneka, Kyowa, Yungjin, etc. Researchs in microbial production of CoQ10 have several steps: screening of producing microorganisms, strain development, fermentation process, purification process, scale-up process, plant production. Several strategies are available for the strain development : Random mutation and screening, directed metabolic engineering. For the optimization of fermentation process, various conditions (nutrient, aeration, temperature, culture type, etc.) are considered. Purification is one of the most important step because the quality of final products entirely depends on its purity. The production cost will be reduced and the quality of the CoQ10 will be impoved by continuous researches in strain development, fermentation process, purification process.

• Journal of Intelligence and Information Systems
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• v.24 no.2
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• pp.21-35
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• 2018

Since the introduction of MP3 players, CD recordings have gradually been vanishing, and the music consuming environment of music users is shifting to mobile devices. The introduction of smart devices has increased the utilization of music through music playback, mass storage, and search functions that are integrated into smartphones and tablets. At the time of initial MP3 player supply, the bitrate of the compressed music contents generally was 128 Kbps. However, as increasing of the demand for high quality music, sound quality of 384 Kbps appeared. Recently, music content of FLAC (Free License Audio Codec) format using lossless compression method is becoming popular. The download service of many music sites in Korea has classified by unlimited download with technical protection and limited download without technical protection. Digital Rights Management (DRM) technology is used as a technical protection measure for unlimited download, but it can only be used with authenticated devices that have DRM installed. Even if music purchased by the user, it cannot be used by other devices. On the contrary, in the case of music that is limited in quantity but not technically protected, there is no way to enforce anyone who distributes it, and in the case of high quality music such as FLAC, the loss is greater. In this paper, the author proposes an audio watermarking technology for copyright protection of high quality stereo music. Two kinds of information, "Copyright" and "Copy_free", are generated by using the turbo code. The two watermarks are composed of 9 bytes (72 bits). If turbo code is applied for error correction, the amount of information to be inserted as 222 bits increases. The 222-bit watermark was expanded to 1024 bits to be robust against additional errors and finally used as a watermark to insert into stereo music. Turbo code is a way to recover raw data if the damaged amount is less than 15% even if part of the code is damaged due to attack of watermarked content. It can be extended to 1024 bits or it can find 222 bits from some damaged contents by increasing the probability, the watermark itself has made it more resistant to attack. The proposed algorithm uses quantization in DCT so that watermark can be detected efficiently and SNR can be improved when stereo music is converted into mono. As a result, on average SNR exceeded 40dB, resulting in sound quality improvements of over 10dB over traditional quantization methods. This is a very significant result because it means relatively 10 times improvement in sound quality. In addition, the sample length required for extracting the watermark can be extracted sufficiently if the length is shorter than 1 second, and the watermark can be completely extracted from music samples of less than one second in all of the MP3 compression having a bit rate of 128 Kbps. The conventional quantization method can extract the watermark with a length of only 1/10 compared to the case where the sampling of the 10-second length largely fails to extract the watermark. In this study, since the length of the watermark embedded into music is 72 bits, it provides sufficient capacity to embed necessary information for music. It is enough bits to identify the music distributed all over the world. 272 can identify $4*10^{21}$, so it can be used as an identifier and it can be used for copyright protection of high quality music service. The proposed algorithm can be used not only for high quality audio but also for development of watermarking algorithm in multimedia such as UHD (Ultra High Definition) TV and high-resolution image. In addition, with the development of digital devices, users are demanding high quality music in the music industry, and artificial intelligence assistant is coming along with high quality music and streaming service. The results of this study can be used to protect the rights of copyright holders in these industries.

• Nuclear Engineering and Technology
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• v.43 no.6
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• pp.583-592
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• 2011

The radiological characteristics for waste classification were assessed for neutron-activated decommissioning wastes from a CANDU reactor. The MCNP/ORIGEN2 code system was used for the source term analysis. The neutron flux and activation cross-section library for each structural component generated by MCNP simulation were used in the radionuclide buildup calculation in ORIGEN2. The specific activities of the relevant radionuclides in the activated metal waste were compared with the specified limits of the specific activities listed in the Korean standard and 10 CFR 61. The time-average full-core model of Wolsong Unit 1 was used as the neutron source for activation of in-core and ex-core structural components. The approximated levels of the neutron flux and cross-section, irradiated fuel composition, and a geometry simplification revealing good reliability in a previous study were used in the source term calculation as well. The results revealed the radioactivity, decay heat, hazard index, mass, and solid volume for the activated decommissioning waste to be $1.04{\times}10^{16}$ Bq, $2.09{\times}10^3$ W, $5.31{\times}10^{14}\;m^3$-water, $4.69{\times}10^5$ kg, and $7.38{\times}10^1\;m^3$, respectively. According to both Korean and US standards, the activated waste of the pressure tubes, calandria tubes, reactivity devices, and reactivity device supporters was greater than Class C, which should be disposed of in a deep geological disposal repository, whereas the side structural components were classified as low- and intermediate-level waste, which can be disposed of in a land disposal repository. Finally, this study confirmed that, regardless of the cooling time of the waste, 15% of the decommissioning waste cannot be disposed of in a land disposal repository. It is expected that the source terms and waste classification evaluated through this study can be widely used to establish a decommissioning/disposal strategy and fuel cycle analysis for CANDU reactors.