• The Journal of Korean Academy of Prosthodontics
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• v.36 no.4
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• pp.587-597
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• 1998

In this study, the Periotest value was measured with Periotest to evaluate precision fit of the 2-unit and 3-unit implant-supported prosthesis by modifying the size and location of ill-fitted conditions. The 2-unit prosthesis was fabricated with the right implant fitted incorrectly and the 3-unit prosthesis with the right and center implant fitted incorrectly. To evaluate the effects of the ill-fitted sizes, 4 groups were divided.:The control group being the accurately fabricated sample group fitted properly. Group 1 was constructed with $40{\mu}m$ ill-fitted conditions, group 2 with $70{\mu}m$ and group 3 with $100{\mu}m$ ill-fitted conditions. The Periotest value was measured at each implant site after tightening 10Ncm. The result was follows : 1. The PTV on the ill-fitted area in the 2-unit implant-supported prosthesis increased as the ill-fitted conditions increased. There was a statistically significant difference among groups(p<0.05). In the same ill-fitted sample, the PTV depending on the measured location demonstrated a statistically significant difference (p<0.05) 2. The PTV on the ill-fitted area of the 3-unit implant-supported with an ill-fitted condition in the right implant increased as the ill-fitted conditions increased. There was a significant difference among groups (p<0.05). In the same ill-fitted sample, the PTV depending on the measured location demonstrated a statistically significant difference (p<0.05). 3. In the 3-unit implant-supported prosthesis with ill fitting conditions in the center implant, the PTV on the ill-fitted area demonstrated a statistically significant difference between the control group, group 1 and group 2 (p<0.05). In the same ill-fitted sample, the PTV depending on the measured location demonstrated significant difference between the gap side and the adjacent side with over $70{\mu}m$ ill-fitted conditions (p<0.05). The results suggest that Periotest is a valuable objective method for evaluating the precision fit of an implant superstructure.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.12
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• pp.1087-1092
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• 2010

A micro 3D-PTV system has been constructed using a single camera system. Two viewing holes were created behind the object lens of the microscopic system to construct a stereoscopic viewing image. A hybrid recursive PTV algorithm was used. A concept of epipolar line was adopted to eliminate many spurious candidates. Three-dimensional velocity vector fields were obtained by calculating the three-dimensional displacements of particles that were identified as being identical. The system consists of a laser light source (Ar-ion, 500 mW), one high-definition camera ($1028{\times}1024$ pixels, 500 fps), a circular plate with two viewing holes, and a host computer. The performance of the developed algorithm was tested using artificial images. The characteristic of the vector recovery ratio was investigated for the particle numbers. A micro backward-facing step channel ($H{\times}h{\times}W:\;36{\mu}m{\times}70{\mu}m{\times}3000{\mu}m$) was measured using the developed measurement system. The results were in good qualitative agreement with other results.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.39 no.7
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• pp.549-555
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• 2015

A measurement technique of interfacial velocity in air-water separated flow by particle tracking velocimetry using an infrared camera (IR-PTV) was developed. As infrared light with wavelength in the range of 3-5 um could hardly penetrate water, IR-PTV can selectively visualize only the tracer particles existing in depths less than 20 um underneath the air-water interface. To validate the measurement accuracy of the IR-PTV technique, a measurement of the interfacial velocity of the air-water separated flow using Styrofoam particles floating in water was conducted. The interfacial velocity values obtained with the two different measurement techniques showed good agreement with errors less than 5%. It was found from the experimental results obtained using the developed technique that with increasing air velocity, the interfacial velocity proportionally increases, likely because of the increased interfacial stress.

• Radiation Oncology Journal
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• v.31 no.2
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• pp.104-110
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• 2013

Purpose: Intensity modulated arc therapy (IMAT) is a form of intensity modulated radiation therapy (IMRT) that delivers dose in single or multiple arcs. We compared IMRT plans versus single-arc field (1ARC) and multi-arc fields (3ARC) IMAT plans in high-risk prostate cancer. Materials and Methods: Sixteen patients were studied. Prostate ($PTV_P$), right pelvic ($PTV_{RtLN}$) and left pelvic lymph nodes ($PTV_{LtLN}$), and organs at risk were contoured. $PTV_P$, $PTV_{RtLN}$, and $PTV_{LtLN}$ received 50.40 Gy followed by a boost to $PTV_B$ of 28.80 Gy. Three plans were per patient generated: IMRT, 1ARC, and 3ARC. We recorded the dose to the PTV, the mean dose ($D_{MEAN}$) to the organs at risk, and volume covered by the 50% isodose. Efficiency was evaluated by monitor units (MU) and beam on time (BOT). Conformity index (CI), Paddick gradient index, and homogeneity index (HI) were also calculated. Results: Average Radiation Therapy Oncology Group CI was 1.17, 1.20, and 1.15 for IMRT, 1ARC, and 3ARC, respectively. The plans' HI were within 1% of each other. The $D_{MEAN}$ of bladder was within 2% of each other. The rectum $D_{MEAN}$ in IMRT plans was 10% lower dose than the arc plans (p < 0.0001). The GI of the 3ARC was superior to IMRT by 27.4% (p = 0.006). The average MU was highest in the IMRT plans (1686) versus 1ARC (575) versus 3ARC (1079). The average BOT was 6 minutes for IMRT compared to 1.3 and 2.9 for 1ARC and 3ARC IMAT (p < 0.05). Conclusion: For high-risk prostate cancer, IMAT may offer a favorable dose gradient profile, conformity, MU and BOT compared to IMRT.

• Journal of the Korean Society of Visualization
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• v.4 no.2
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• pp.69-75
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• 2006

The microbubbles were used in various fields, such as turbulent control, drag reduction, material science and life science. The X-ray PTV using X-ray micro-imaging technique was employed to mea-sure the size and velocity of micro-bubbles moving in an opaque tube simultaneously. Micro-bubbles of $10{\sim}60{\mu}m$ diameter moving upward in an opaque tube (${\phi}$=2.7mm) were tested. Due to the different refractive indices of water and air, phase contrast X-ray images clearly show the exact size and shape of over-lapped microbubbles. In all of the working fluids tested (deionized water, tap water, 0.01 and 0.10M NaCl solutions), the measured terminal velocity of the microbubbles rising through the solution was proportional to the square of the bubble diameter. The rising velocity was increased with increasing mole concentration. The microbubble can be useful as contrast agent or tracer in life science and biology. The X-ray PTV technique should be able to extract useful information on the behavior of various bio/microscale fluid flows that are not amenable to analysis using conventional methods.

• The Journal of Korean Society for Radiation Therapy
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• v.31 no.2
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• pp.33-41
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• 2019

Purpose: The purpose of this study is to improve the reduction of coverage of PTVs adjacent to organ at risk (OAR) by setting up overlapping Planning Target Volume (PTV) during Volumetric Modulated Arc Therapy(VMAT). Materials and Methods: In patients who received Whole Brain, Gall Bladder and Rectum radiation therapy, We compared the cover change, maximum dose, Homogenicity Index and Conformity Index of PTV and also compared the maximum dose and average dose change of Organ At Risk by organizing treatment plans that are not applied overlaped PTV and treatment plans that are applied overlaped PTV in areas where coverage is insufficient. Results: overage of treatment plans with overlapping PTVs was increased in all patients, and overall coverage was also increased in each of the four patients. The maximum dose for PTV was increased in five patients, and the Homogenicity Index and Conformity Index for all patients did not differ much. The maximum dose of the lens was increased by 1.12 times, and the maximum dose was decreased in two patients for brain stem. The mean dose of the eyeball was increased by a maximum of 1.15 times, and there was no significant difference between both parotid gland. In case of gallbladder cancer patients, the mean dose in the liver and colon was decreased, and the mean dose in the duodenum was increased. In the case of rectal cancer patients, the mean dose was reduced for both femur and bladder set as OARs. The overall MU was shown to be similar in four patients, excluding one. Conclusion: If the critical dose of OAR is considered and used properly, I think it is a useful way to improve coverage of PTV.

• The Journal of Korean Society for Radiation Therapy
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• v.33
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• pp.127-135
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• 2021

Purpose : The purpose of the study is to evaluate the efficiency of Vertical MLC VMAT plan(VMV plan) Using 273° and 350° collimator angle compare to Complemental MLC VMAT plan(CMV plan) using 20° and 340° collimator angle for nasopharyngeal carcinoma. Materials & Methods : Thirty patients treated for nasopharyngeal carcinoma with the VMAT technique were retrospectively selected. Those cases were planned by Eclipse, PO and AcurosXB Algorithm with two 6MV 360° arcs and Each arc has 273° and 350° of collimator angle. The Complemental MLC VMAT plans are based on existing treatment plans. Those plans have the same parameters of existing treatment plans but collimator angle. For dosimetric evaluation, the dose-volumetric(DV) parameters of the planning target volume (PTV) and organs at risk (OARs) were calculated for all VMAT plans. MCSv(Modulation complexity score of VMAT), MU and treatment time were also compared. In addition, Pearson's correlation analysis was performed to confirm whether there was a correlation between the difference in the MCSv and the difference in each evaluation index of the two treatment plans. Result : In the case of PTV evaluation index, the CI of PTV_67.5 was improved by 3.76% in the VMV Plan, then for OAR, the dose reduction effect of the spinal cord (-14.05%) and brain stem (-9.34%) was remarkable. In addition, the parotid glands (left parotid : -5.38%, right : -5.97%) and visual organs (left optic nerve: -4.88%, right optic nerve: -5.80%, optic chiasm : -6.12%, left lens: -6.12%, right lens: -5.26%), auditory organs (left: -11.74%, right: -12.31%) and thyroid gland (-2.02%) were also confirmed. The difference in MCSv of the two treatment plans showed a significant negative (-) correlation with the difference in CI (r=-0.55) of PTV_54 and the difference in CI (r=-0.43) of PTV_48. Spinal cord (r=0.40), brain stem (r=0.34), and both salivary glands (left: r=0.36, right: r=0.37) showed a positive (+) correlation. (For all the values, p<.05) Conclusion : Compared to the CMV plan, the VMV plan is considered to be helpful in improving the quality of the treatment plan by allowing the MLC to be modulated more efficiently

• The Journal of Korean Society for Radiation Therapy
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• v.27 no.1
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• pp.31-43
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• 2015

Purpose : Stereotactic body radiation therapy (SBRT) has proved its efficacy in several patient populations with primary and metastatic limited tumors. Because SBRT prescription is high dose level than Conventional radiation therapy. SBRT plan is necessary for effective Organ at risk (OAR) protection and sufficient Planning target volume (PTV) dose coverage. In particular, multi-target cases may result excessive doses to OAR and hot spot due to dose overlap. This study evaluate usefulness of Volumetric modulated arc therapy (VMAT) in dosimetric and technical considerations using Flattening filter free (FFF) beam. Materials and Methods : The treatment plans for five patients, being treated on TrueBeam STx(Varian$^{TM}$, USA) with VMAT using 10MV FFF beam and Standard conformal radiotherapy (CRT) using 15MV Flattening filter (FF) beam. PTV, liver, duodenum, bowel, spinal cord, esophagus, stomach dose were evaluated using the dose volume histogram(DVH). Conformity index(CI), homogeneity index(HI), Paddick's index(PCI) for the PTV was assessed. Total Monitor unit (MU) and beam on time was assessed. Results : Average value of CI, HI and PCI for PTV was $1.381{\pm}0.028$, $1.096{\pm}0.016$, $0.944{\pm}0.473$ in VMAT and $1.381{\pm}0.042$, $1.136{\pm}0.042$, $1.534{\pm}0.465$ in CRT respectively. OAR dose in CRT plans evaluated 1.8 times higher than VMAT. Total MU in VMAT evaluated 1.3 times increase than CRT. Average beam on time was 6.8 minute in VMAT and 21.3 minute in CRT. Conclusion : VMAT for SBRT in multi-target liver cancer using FFF beam is effective treatment techniqe in dosimetric and technical considerations. VMAT decrease intra-fraction error due to treatment time shortening using high dose rate of FFF beam.

• Progress in Medical Physics
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• v.17 no.1
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• pp.24-31
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• 2006

Automated analysis software was developed to measure the magnitude of the intrafractional and interfractional errors during breast radiation treatments. Error analysis results are important for determining suitable planning target volumes (PTV) prior to Implementing breast-conserving 3-D conformal radiation treatment (CRT). The electrical portal imaging device (EPID) used for this study was a Portal Vision LC250 liquid-filled ionization detector (fast frame-averaging mode, 1.4 frames per second, 256X256 pixels). Twelve patients were imaged for a minimum of 7 treatment days. During each treatment day, an average of 8 to 9 images per field were acquired (dose rate of 400 MU/minute). We developed automated image analysis software to quantitatively analyze 2,931 images (encompassing 720 measurements). Standard deviations ($\sigma$) of intrafractional (breathing motion) and intefractional (setup uncertainty) errors were calculated. The PTV margin to include the clinical target volume (CTV) with 95% confidence level was calculated as $2\;(1.96\;{\sigma})$. To compensate for intra-fractional error (mainly due to breathing motion) the required PTV margin ranged from 2 mm to 4 mm. However, PTV margins compensating for intefractional error ranged from 7 mm to 31 mm. The total average error observed for 12 patients was 17 mm. The intefractional setup error ranged from 2 to 15 times larger than intrafractional errors associated with breathing motion. Prior to 3-D conformal radiation treatment or IMRT breast treatment, the magnitude of setup errors must be measured and properly incorporated into the PTV. To reduce large PTVs for breast IMRT or 3-D CRT, an image-guided system would be extremely valuable, if not required. EPID systems should incorporate automated analysis software as described in this report to process and take advantage of the large numbers of EPID images available for error analysis which will help Individual clinics arrive at an appropriate PTV for their practice. Such systems can also provide valuable patient monitoring information with minimal effort.

• Proceedings of the KSME Conference
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• 2007.05b
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• pp.2579-2584
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• 2007

A digital micro holographic particle tracking velocimetry (HPTV) system consisting of a high-speed camera and a single laser with acoustic optical modulator (AOM) chopper was established. The digital micro HPTV system was applied to water flow in a micro curved-tube for measuring instantaneous 3-D velocity field data consecutively. The micro curved-tube is using to reproduce the dorsal aorta or utilize in various lap-on-a-chip. The temporal evolution of a three-dimensional water flow in the micro curved-tube (the curvature, ${\kappa}$=1/${\phi}$, 2/${\phi}$, 4/${\phi}$, 8/${\phi}$) of 100 ${\mu}m$ and 300 ${\mu}m$ inner diameters was obtained and mean velocity field distribution was obtained by statistical-averaging the instantaneous velocity fields.